K00088


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00088, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00088
KO K00088
Description IMP dehydrogenase [EC:1.1.1.205]

KO part of 5 pathways

Purine metabolism
Drug metabolism - other enzymes
Metabolic pathways
Biosynthesis of secondary metabolites
Nucleotide metabolism

KO part of 1 modules

M00050 Purine metabolism Guanine ribonucleotide biosynthesis, IMP => GDP,GTP

Occurence in the database

K00088 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_2232 PMI_RS07525 1639689 1641155 -1 guaB IMP dehydrogenase Proteus mirabilis HI4320
1 group_2232 FBDBKF_17105 4819 6285 -1 guaB IMP dehydrogenase Morganella morganii S1
2 group_2232 EHELCC_01785 349216 350682 1 guaB IMP dehydrogenase Morganella morganii S2
3 group_2232 NLDBIP_01675 329454 330920 -1 guaB IMP dehydrogenase Morganella morganii S4
4 group_2232 LHKJJB_00360 61765 63231 1 guaB IMP dehydrogenase Morganella morganii S3
5 group_2232 HKOGLL_00400 67276 68742 1 guaB IMP dehydrogenase Morganella morganii S5
6 group_2232 F4V73_RS05865 1249233 1250699 -1 guaB IMP dehydrogenase Morganella psychrotolerans