Orthogroup:group_660



Homologs in group_660

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7 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Source Gene Product
FBDBKF_02340 FBDBKF_02340 Morganella morganii S1 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase
EHELCC_02810 EHELCC_02810 Morganella morganii S2 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase
NLDBIP_00650 NLDBIP_00650 Morganella morganii S4 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase
LHKJJB_01385 LHKJJB_01385 Morganella morganii S3 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase
HKOGLL_01425 HKOGLL_01425 Morganella morganii S5 ldhA Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase
F4V73_RS04720 F4V73_RS04720 Morganella psychrotolerans - 2-hydroxyacid dehydrogenase
PMI_RS05700 PMI_RS05700 Proteus mirabilis HI4320 - 2-hydroxyacid dehydrogenase

Distribution of group_660 homologs

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Number of homologs in each genome (first column and blue bar chart)

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Phylogeny of group_660 (midpoint rooted)


Phylogeny of the RefSeq best hits of group_660

Orthogroup content: 7 members

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This page summarizes the annotation of all members of the orthologous group group_660.
Gene name(s), gene product(s), a summary of protein lenght, and annotations (when available) are provided. Additionally, the number of times (occurence) an annotation is observed in the orthogroup is reported for each annotation.

Orthologs were identified with OrthoFinder. The annotation of orthologous proteins can differ depending the approach used to annotate the source genomes. Automated annotations are also subject to errors. Spurious clustering of non-orthologous proteins can also happen. This page allows to check for eventual inconsistencies.

Gene

# Gene name Occurence
1 ldhA 5
2 - 2

Product

# Product Occurence
1 Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase 5
2 2-hydroxyacid dehydrogenase 2

COG entry Annotation(s)

ID Occurences Function(s) cat. Function(s) descr. Description
COG1052 7 CHR Energy production and conversion (C)
Coenzyme transport and metabolism (H)
General function prediction only (R)
Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase

Kegg Ortholog Annotation(s)

KO Occurences Description Pathways Modules
K03778 7 D-lactate dehydrogenase [EC:1.1.1.28] Pyruvate metabolism
Metabolic pathways
Microbial metabolism in diverse environments
-

Pfam domain Annotation(s)

Domain ID Occurences Description
PF00389 7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PF02826 7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain

Annotations of the 405 SwissProt hits

Annotation Number of occurrences
(R)-2-hydroxyglutarate dehydrogenase 1
(S)-sulfolactate dehydrogenase 1
2-hydroxyacid dehydrogenase A 1
2-hydroxyacid dehydrogenase homolog 2
2-hydroxyacid dehydrogenase homolog 1 1
2-hydroxyacid dehydrogenase homolog 2 1
2-ketogluconate reductase 1
4-methyl-2-oxopentanoate reductase A 1
Aromatic 2-oxoacid reductase 2
C-terminal binding protein AN 1
C-terminal-binding protein 1
C-terminal-binding protein 1 5
C-terminal-binding protein 2 5
D-2-hydroxyacid dehydrogenase 1
D-2-hydroxyacid dehydrogenase (NAD(+)) 1
D-2-hydroxyacid dehydrogenase (NAD+) 1
D-3-phosphoglycerate dehydrogenase 23
D-3-phosphoglycerate dehydrogenase 1 1
D-3-phosphoglycerate dehydrogenase 1, chloroplastic 1
D-3-phosphoglycerate dehydrogenase 2 1
D-3-phosphoglycerate dehydrogenase 2, chloroplastic 1
D-3-phosphoglycerate dehydrogenase 3, chloroplastic 1
D-lactate dehydrogenase 19
D-lactate dehydrogenase kk1H 1
D-lactate/D-glycerate dehydrogenase 1
D-specific alpha-keto acid dehydrogenase 2
Dehydrogenase efuE 1
Erythronate-4-phosphate dehydrogenase 152
Erythronate-4-phosphate dehydrogenase (Fragment) 1
Formate dehydrogenase 6
Formate dehydrogenase 1 4
Formate dehydrogenase 1, mitochondrial 1
Formate dehydrogenase 2 1
Formate dehydrogenase 2, mitochondrial 1
Formate dehydrogenase, chloroplastic/mitochondrial 1
Formate dehydrogenase, mitochondrial 2
Glycerate dehydrogenase 3
Glycerate dehydrogenase HPR, peroxisomal 1
Glyoxylate reductase 10
Glyoxylate reductase 1 1
Glyoxylate reductase/hydroxypyruvate reductase 2
Glyoxylate/hydroxypyruvate reductase A 46
Glyoxylate/hydroxypyruvate reductase A HPR2 1
Glyoxylate/hydroxypyruvate reductase B 62
Glyoxylate/hydroxypyruvate reductase HPR3 1
Glyoxylate/hydroxypyruvate/pyruvate reductase 2KGR 1
Hydroxyphenylpyruvate reductase 1
Hydroxypyruvate reductase 2
Phosphonate dehydrogenase 1
Probable 2-ketogluconate reductase 2
Putative 2-hydroxyacid dehydrogenase C1773.17c 1
Putative 2-hydroxyacid dehydrogenase HI_1556 1
Putative 2-hydroxyacid dehydrogenase MW2224 1
Putative 2-hydroxyacid dehydrogenase SA2098 1
Putative 2-hydroxyacid dehydrogenase SAB2178 1
Putative 2-hydroxyacid dehydrogenase SACOL2296 1
Putative 2-hydroxyacid dehydrogenase SAOUHSC_02577 1
Putative 2-hydroxyacid dehydrogenase SAR2389 1
Putative 2-hydroxyacid dehydrogenase SAS2196 1
Putative 2-hydroxyacid dehydrogenase SAUSA300_2254 1
Putative 2-hydroxyacid dehydrogenase SAV2305 1
Putative 2-hydroxyacid dehydrogenase SERP1888 1
Putative 2-hydroxyacid dehydrogenase SE_1879 1
Putative 2-hydroxyacid dehydrogenase SH0752 1
Putative 2-hydroxyacid dehydrogenase SSP0606 1
Putative 2-hydroxyacid dehydrogenase UNK4.10 1
Putative 2-hydroxyacid dehydrogenase YGL185C 1
Putative 2-hydroxyacid dehydrogenase YPL113C 1
Putative 2-hydroxyacid dehydrogenase YoaD 1
Putative D-3-phosphoglycerate dehydrogenase 1
Putative D-lactate dehydrogenase 1
Truncated formate dehydrogenase 2 1
Uncharacterized protein Cgl2355/cg2587 1
Uncharacterized protein in proB 3'region 1

Protein length

Min length 332
Max length 334
Mean length (sd) 333.0 (0.6)
Median length 333.0

Protein length distribution