Orthogroup:group_1913


Homologs in group_1913

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7 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Source Gene Product
FBDBKF_14250 FBDBKF_14250 Morganella morganii S1 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
EHELCC_08030 EHELCC_08030 Morganella morganii S2 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
NLDBIP_08355 NLDBIP_08355 Morganella morganii S4 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
LHKJJB_05910 LHKJJB_05910 Morganella morganii S3 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
HKOGLL_05005 HKOGLL_05005 Morganella morganii S5 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
F4V73_RS02660 F4V73_RS02660 Morganella psychrotolerans folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
PMI_RS08760 PMI_RS08760 Proteus mirabilis HI4320 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase

Distribution of group_1913 homologs

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Number of homologs in each genome (first column and blue bar chart)

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Phylogeny of group_1913 (midpoint rooted)


Phylogeny of the RefSeq best hits of group_1913

Orthogroup content: 7 members

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This page summarizes the annotation of all members of the orthologous group group_1913.
Gene name(s), gene product(s), a summary of protein lenght, and annotations (when available) are provided. Additionally, the number of times (occurence) an annotation is observed in the orthogroup is reported for each annotation.

Orthologs were identified with OrthoFinder. The annotation of orthologous proteins can differ depending the approach used to annotate the source genomes. Automated annotations are also subject to errors. Spurious clustering of non-orthologous proteins can also happen. This page allows to check for eventual inconsistencies.

Gene

# Gene name Occurence
1 folC 7

Product

# Product Occurence
1 bifunctional tetrahydrofolate synthase/dihydrofolate synthase 7

COG entry Annotation(s)

ID Occurences Function(s) cat. Function(s) descr. Description
COG0285 7 H Coenzyme transport and metabolism (H) Folylpolyglutamate synthase/Dihydropteroate synthase

Kegg Ortholog Annotation(s)

KO Occurences Description Pathways Modules
K11754 7 dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] Folate biosynthesis
Metabolic pathways
Biosynthesis of cofactors		 Tetrahydrofolate biosynthesis, GTP => THF
Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF

Pfam domain Annotation(s)

Domain ID Occurences Description
PF02875 7 Mur ligase, glutamate ligase domain
PF08245 7 Mur ligase middle domain

Annotations of the 57 SwissProt hits

Annotation Number of occurrences
Dihydrofolate synthase/folylpolyglutamate synthase 7
Dihydrofolate synthetase 2
Folylpolyglutamate synthase 16
Folylpolyglutamate synthase, mitochondrial 4
Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase 2
Probable dihydrofolate synthetase 1
Probable folylpolyglutamate synthase 1
Putative folylpolyglutamate synthase 2
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase 17
UDP-N-acetylmuramoylalanine--D-glutamate ligase 3
UDP-N-acetylmuramyl-tripeptide synthetase 2

Protein length

Min length 432
Max length 450
Mean length (sd) 445.0 (8.5)
Median length 450.0

Protein length distribution