Homologs in group_168

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9 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_16725 FBDBKF_16725 90.7 Morganella morganii S1 hcp Type VI protein secretion system component Hcp (secreted cytotoxin)
EHELCC_10735 EHELCC_10735 90.7 Morganella morganii S2 hcp Type VI protein secretion system component Hcp (secreted cytotoxin)
NLDBIP_11080 NLDBIP_11080 90.7 Morganella morganii S4 hcp Type VI protein secretion system component Hcp (secreted cytotoxin)
LHKJJB_10275 LHKJJB_10275 90.7 Morganella morganii S3 hcp Type VI protein secretion system component Hcp (secreted cytotoxin)
HKOGLL_16440 HKOGLL_16440 90.7 Morganella morganii S5 hcp Type VI protein secretion system component Hcp (secreted cytotoxin)
F4V73_RS05140 F4V73_RS05140 89.0 Morganella psychrotolerans - Hcp family type VI secretion system effector
PMI_RS00995 PMI_RS00995 91.9 Proteus mirabilis HI4320 - Hcp family type VI secretion system effector
PMI_RS03690 PMI_RS03690 98.3 Proteus mirabilis HI4320 - Hcp family type VI secretion system effector
PMI_RS05420 PMI_RS05420 98.8 Proteus mirabilis HI4320 - Hcp family type VI secretion system effector

Distribution of the homologs in the orthogroup group_168

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_168

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q9HI36 2.64e-74 223 60 0 170 1 hcpA Major exported protein Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P80693 2.58e-16 72 62 0 56 1 None Major exported protein (Fragment) Pseudomonas syringae pv. ribicola
P46855 5.35e-09 57 25 4 160 3 yhhZ Uncharacterized protein YhhZ Escherichia coli (strain K12)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS14785
Feature type CDS
Gene -
Product Hcp family type VI secretion system effector
Location 3278930 - 3279448 (strand: 1)
Length 519 (nucleotides) / 172 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_168
Orthogroup size 10
N. genomes 7

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Genomic region

Domains

PF05638 Type VI secretion system effector, Hcp

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG3157 Intracellular trafficking, secretion, and vesicular transport (U) U Type VI protein secretion system component Hcp (secreted cytotoxin)

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K11903 type VI secretion system secreted protein Hcp Biofilm formation - Pseudomonas aeruginosa
Bacterial secretion system		 -

Virulence factor Annotation(s)

VF gene ID Protein VF ID Category
VFG038370 hemolysin co-regulated protein VF0480 Effector delivery system

Protein Sequence

MPTPCYISIEGKTQGNITAGAFTADSVGNIYVQGHEDQMLVQAFSHVVTVPTDPQSGQPSGQRAHKPFRFTVALNKAVPLLYNALASGEMLPKVELKWYRTSVEGKQEHFFTTTLTDATIVNIDCQMPHCQDPAKADFTQLIEVSLSYRKVDWEHTVAGTSGADDWRAPLEA

Flanking regions ( +/- flanking 50bp)

TAAGACAATCATTTAATTTAATTTGTCATTTTTAATAAAAGGATCTCATTATGCCAACTCCTTGCTATATTTCCATTGAAGGAAAAACTCAGGGCAACATCACTGCAGGCGCGTTTACTGCAGATTCTGTCGGCAACATTTATGTACAAGGTCATGAAGACCAAATGTTGGTGCAAGCATTTTCTCATGTGGTGACAGTACCGACCGATCCGCAATCAGGACAACCTTCCGGCCAACGTGCGCATAAACCATTTCGTTTTACCGTGGCATTAAATAAAGCGGTTCCCCTGCTATATAACGCATTGGCTTCCGGCGAAATGTTGCCAAAAGTTGAGCTAAAATGGTATCGCACCTCGGTAGAAGGTAAACAAGAGCACTTCTTTACCACCACACTGACTGACGCGACTATCGTGAACATCGATTGCCAAATGCCTCATTGCCAAGATCCGGCTAAAGCCGACTTCACGCAACTTATCGAAGTCTCCCTCTCTTACCGCAAAGTTGACTGGGAGCATACTGTTGCCGGGACTTCAGGTGCAGATGACTGGCGTGCACCACTCGAAGCATAAGTCATGGGTTAAACGAGTCCTTAGGGGCTCGTTTACCGTTTTAGTCTCCT