Homologs in group_2309

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_17485 FBDBKF_17485 77.6 Morganella morganii S1 hypE hydrogenase expression/formation protein HypE
EHELCC_17380 EHELCC_17380 77.6 Morganella morganii S2 hypE hydrogenase expression/formation protein HypE
NLDBIP_17815 NLDBIP_17815 77.6 Morganella morganii S4 hypE hydrogenase expression/formation protein HypE
LHKJJB_17735 LHKJJB_17735 77.6 Morganella morganii S3 hypE hydrogenase expression/formation protein HypE
HKOGLL_17745 HKOGLL_17745 77.6 Morganella morganii S5 hypE hydrogenase expression/formation protein HypE
F4V73_RS16660 F4V73_RS16660 78.5 Morganella psychrotolerans hypE hydrogenase expression/formation protein HypE

Distribution of the homologs in the orthogroup group_2309

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2309

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P24193 1.68e-167 472 66 0 335 1 hypE Carbamoyl dehydratase HypE Escherichia coli (strain K12)
P26412 1.22e-101 305 47 3 338 3 hypE Carbamoyl dehydratase HypE Rhodobacter capsulatus
P40599 1.65e-101 305 45 3 338 3 hypE Carbamoyl dehydratase HypE Rhizobium leguminosarum bv. viciae
P31906 3.7e-101 304 44 3 337 3 hypE Carbamoyl dehydratase HypE Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
P40595 1.85e-97 295 44 3 336 3 hypE Carbamoyl dehydratase HypE Azotobacter vinelandii
P42034 2.49e-95 289 43 3 336 3 hupE Hydrogenase expression/formation protein HupE Azotobacter chroococcum mcd 1
P31905 2.26e-85 264 44 3 323 1 hypE Carbamoyl dehydratase HypE Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)
Q58089 3.1e-73 233 37 5 342 3 MJ0676 Putative hydrogenase expression/formation protein MJ0676 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
O27447 4.55e-08 57 25 9 248 3 thiL Thiamine-monophosphate kinase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
O59497 3.45e-06 51 24 7 245 3 thiL Thiamine-monophosphate kinase Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
P57532 1.47e-05 49 23 9 241 3 thiL Thiamine-monophosphate kinase Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
O67883 0.000168 46 19 4 205 1 thiL Thiamine-monophosphate kinase Aquifex aeolicus (strain VF5)
Q5WJ84 0.000279 45 27 12 276 3 purM Phosphoribosylformylglycinamidine cyclo-ligase Shouchella clausii (strain KSM-K16)
Q60BU2 0.000305 45 24 9 258 3 purM Phosphoribosylformylglycinamidine cyclo-ligase Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
C0ZKC8 0.000707 44 24 14 319 3 purM Phosphoribosylformylglycinamidine cyclo-ligase Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)
Q8XE87 0.000811 44 25 8 268 3 thiL Thiamine-monophosphate kinase Escherichia coli O157:H7
P0AGG0 0.001 44 25 9 270 1 thiL Thiamine-monophosphate kinase Escherichia coli (strain K12)
P0AGG1 0.001 44 25 9 270 3 thiL Thiamine-monophosphate kinase Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS00195
Feature type CDS
Gene hypE
Product hydrogenase expression/formation protein HypE
Location 61992 - 63011 (strand: 1)
Length 1020 (nucleotides) / 339 (amino acids)
In genomic island -

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_2309
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00586 AIR synthase related protein, N-terminal domain
PF02769 AIR synthase related protein, C-terminal domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0309 Posttranslational modification, protein turnover, chaperones (O) O Carbamoyl dehydratase HypE (hydrogenase maturation factor)

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K04655 hydrogenase expression/formation protein HypE - -

Protein Sequence

MKQPDEITLAQGNGGQGMQQLIEGLFLKAFDNPLLNEKEDQARIALADLTAQGDRLAFSTDSYVIDPIIFPGGNIGKLSVCGTANDLSVGGAVPRYLSCGFILEEGLAFETLETLVMAMAKAAQQAGIQIVTGDTKVVPRGAADKIFINTAGIGVIPSKIDWAASHIKAGDKIIVSGTIGDHGATILNLRENLGLEADLQSDCAVLEPMIAPLRQIDGIRALRDATRGGVTAILHEFSQACGCGMNVYENKLPMKQSVRGVCELLGLEALNFANEGKIVLVVSPQAEKQVLEALHQHTLGQDACTIGEVTEERYIRLTGIFGTSRILDLPYNEPLPRIC

Flanking regions ( +/- flanking 50bp)

TCAGAAGGTGCATGTGCGGCTTATTATCAGTATCGCCGTGAAGGTAATATATGAAACAACCTGATGAAATCACCTTAGCTCAAGGAAATGGTGGGCAAGGTATGCAACAACTTATCGAAGGGCTATTTTTGAAAGCATTCGATAATCCATTATTGAATGAAAAAGAAGATCAGGCTCGTATTGCATTAGCCGATCTCACAGCACAGGGCGATCGTCTGGCATTTAGTACCGACAGTTATGTGATTGATCCGATCATTTTCCCAGGTGGAAATATTGGTAAATTATCTGTTTGCGGAACCGCGAACGATCTTTCTGTAGGTGGAGCTGTACCTCGCTATCTCTCTTGTGGTTTTATTTTAGAAGAGGGACTTGCTTTTGAAACGCTAGAAACATTGGTGATGGCGATGGCAAAAGCCGCACAACAAGCAGGTATTCAGATTGTAACGGGGGATACCAAAGTGGTTCCTCGTGGTGCTGCGGATAAGATCTTCATTAATACTGCGGGTATTGGGGTGATCCCAAGTAAAATTGATTGGGCAGCAAGTCACATTAAAGCCGGCGATAAGATCATCGTCAGCGGTACAATAGGCGATCATGGTGCCACTATCTTAAATTTACGTGAAAATTTAGGATTGGAAGCTGATCTGCAAAGTGACTGTGCCGTGCTTGAACCAATGATCGCGCCTTTACGTCAAATTGACGGTATTCGTGCATTACGTGATGCAACTCGTGGTGGCGTGACCGCTATTTTACATGAGTTTTCTCAAGCCTGTGGCTGTGGCATGAATGTATATGAAAACAAACTGCCAATGAAACAGTCTGTACGTGGTGTGTGTGAATTATTAGGGCTGGAAGCACTCAATTTTGCTAACGAAGGTAAAATTGTATTAGTCGTGTCACCGCAAGCAGAAAAACAAGTTCTTGAGGCTTTGCATCAACATACTTTAGGTCAAGATGCTTGTACCATTGGTGAAGTAACTGAAGAGCGTTATATTCGTTTAACGGGAATTTTTGGCACAAGTCGTATTTTAGATCTCCCTTATAACGAGCCATTACCCCGTATTTGTTAATTAAATCAAATCACTCAACTGATCTTTTAAATACTCATAAGTTATTTCTC