Homologs in group_1141

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_06530 FBDBKF_06530 78.9 Morganella morganii S1 thrA bifunctional aspartate kinase/homoserine dehydrogenase I
EHELCC_09575 EHELCC_09575 78.9 Morganella morganii S2 thrA bifunctional aspartate kinase/homoserine dehydrogenase I
NLDBIP_09955 NLDBIP_09955 78.9 Morganella morganii S4 thrA bifunctional aspartate kinase/homoserine dehydrogenase I
LHKJJB_07800 LHKJJB_07800 78.9 Morganella morganii S3 thrA bifunctional aspartate kinase/homoserine dehydrogenase I
HKOGLL_07350 HKOGLL_07350 78.9 Morganella morganii S5 thrA bifunctional aspartate kinase/homoserine dehydrogenase I
F4V73_RS15400 F4V73_RS15400 78.4 Morganella psychrotolerans thrA bifunctional aspartate kinase/homoserine dehydrogenase I

Distribution of the homologs in the orthogroup group_1141

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1141

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P27725 0.0 1320 78 0 819 3 thrA Bifunctional aspartokinase/homoserine dehydrogenase 1 Serratia marcescens
P00561 0.0 1296 76 1 820 1 thrA Bifunctional aspartokinase/homoserine dehydrogenase 1 Escherichia coli (strain K12)
P44505 0.0 1010 62 0 813 3 thrA Bifunctional aspartokinase/homoserine dehydrogenase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P57290 0.0 914 54 3 817 3 thrA Bifunctional aspartokinase/homoserine dehydrogenase Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Q8K9U9 0.0 891 52 2 814 3 thrA Bifunctional aspartokinase/homoserine dehydrogenase Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Q89AR4 0.0 849 50 2 815 3 thrA Bifunctional aspartokinase/homoserine dehydrogenase Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
P49079 0.0 575 37 8 829 2 AKHSDH1 Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic Zea mays
O81852 0.0 569 37 9 825 1 AKHSDH2 Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic Arabidopsis thaliana
Q9SA18 0.0 567 39 13 834 1 AKHSDH1 Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic Arabidopsis thaliana
P37142 0.0 546 37 11 837 1 None Bifunctional aspartokinase/homoserine dehydrogenase, chloroplastic (Fragment) Daucus carota
P49080 3.54e-178 539 36 9 829 2 AKHSDH2 Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic Zea mays
P00562 6.56e-99 328 29 17 823 1 metL Bifunctional aspartokinase/homoserine dehydrogenase 2 Escherichia coli (strain K12)
Q57991 9.17e-84 278 37 9 472 1 MJ0571 Probable aspartokinase Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q57991 9.1e-07 55 36 0 66 1 MJ0571 Probable aspartokinase Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q5B998 4.05e-60 211 41 5 276 1 AN2882 Homoserine dehydrogenase Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
O94671 3.33e-57 203 37 7 335 1 hom6 Homoserine dehydrogenase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
C1G1C3 4.39e-50 184 37 4 275 1 PADG_00663 Homoserine dehydrogenase Paracoccidioides brasiliensis (strain Pb18)
Q9LYU8 2.05e-49 187 30 12 490 1 AK1 Aspartokinase 1, chloroplastic Arabidopsis thaliana
Q9S702 4.28e-46 177 29 12 475 1 AK3 Aspartokinase 3, chloroplastic Arabidopsis thaliana
O23653 1.48e-44 172 28 13 474 1 AK2 Aspartokinase 2, chloroplastic Arabidopsis thaliana
O60163 2.48e-44 171 29 11 496 1 SPBC19F5.04 Probable aspartokinase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P31116 1.48e-41 159 31 11 338 1 HOM6 Homoserine dehydrogenase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q9ZJZ7 2.41e-41 159 31 10 344 3 lysC Aspartokinase Helicobacter pylori (strain J99 / ATCC 700824)
O25827 4.38e-41 159 31 10 344 3 lysC Aspartokinase Helicobacter pylori (strain ATCC 700392 / 26695)
P08660 7.9e-41 159 29 15 464 1 lysC Lysine-sensitive aspartokinase 3 Escherichia coli (strain K12)
P10869 1.88e-40 160 27 13 503 1 HOM3 Aspartokinase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
O69077 4.1e-39 153 28 14 464 1 lysC Aspartokinase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
A4VJB4 1.07e-38 152 28 15 466 1 lysC Aspartate kinase Ask_LysC Stutzerimonas stutzeri (strain A1501)
Q88EI9 4.32e-38 150 29 16 464 1 PP_4473 Aspartate kinase Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
C3JXY0 1.25e-37 149 28 15 463 1 PFLU_4747 Aspartate kinase Pseudomonas fluorescens (strain SBW25)
P94417 6.9e-36 145 26 10 474 1 yclM Aspartokinase 3 Bacillus subtilis (strain 168)
W7MS01 6.25e-34 140 26 20 516 1 FUB3 Aspartate kinase FUB3 Gibberella moniliformis (strain M3125 / FGSC 7600)
P08495 2.88e-33 136 29 9 339 1 lysC Aspartokinase 2 Bacillus subtilis (strain 168)
S0DVT6 1.04e-32 136 26 19 519 1 FUB3 Aspartate kinase FUB3 Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831)
P53553 2.18e-31 130 27 14 463 3 lysC Aspartokinase Geobacillus stearothermophilus
A0A0D2YG09 2.19e-31 133 28 12 382 1 FUB3 Aspartate kinase FUB3 Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)
P61488 2.95e-30 127 30 12 351 3 ask Aspartokinase Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
P26512 3.39e-30 127 28 14 467 1 lysC Aspartokinase Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
P61489 3.87e-30 127 30 12 351 1 ask Aspartokinase Thermus thermophilus
P41398 6.87e-30 126 28 14 467 1 lysC Aspartokinase Corynebacterium flavescens
Q9Z6L0 7.25e-30 127 30 7 297 3 lysC Aspartokinase Chlamydia pneumoniae
O67221 9.97e-30 126 31 11 354 3 lysC Aspartokinase Aquifex aeolicus (strain VF5)
Q8RQN1 1.58e-28 122 27 13 467 3 lysC Aspartokinase Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Q4UK84 3.32e-28 121 25 10 452 3 lysC Aspartokinase Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Q92GF9 1.78e-26 116 26 10 429 3 lysC Aspartokinase Rickettsia conorii (strain ATCC VR-613 / Malish 7)
O84367 2.61e-26 116 24 13 470 3 lysC Aspartokinase Chlamydia trachomatis serovar D (strain ATCC VR-885 / DSM 19411 / UW-3/Cx)
P41403 2.07e-25 113 30 8 284 3 ask Aspartokinase Mycolicibacterium smegmatis
Q59229 2.55e-25 112 27 8 341 1 lysC Aspartokinase Bacillus sp. (strain MGA3)
Q04795 3.64e-24 109 30 8 293 3 dapG Aspartokinase 1 Bacillus subtilis (strain 168)
Q9PK32 7.01e-22 102 25 4 294 3 lysC Aspartokinase Chlamydia muridarum (strain MoPn / Nigg)
P9WPX3 2.84e-21 100 27 8 293 1 ask Aspartokinase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WPX2 2.84e-21 100 27 8 293 3 ask Aspartokinase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P0A4Z9 2.84e-21 100 27 8 293 3 ask Aspartokinase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Q9ZCI7 1.8e-20 99 41 1 121 3 lysC Aspartokinase Rickettsia prowazekii (strain Madrid E)
Q68VZ7 2.49e-20 98 41 1 121 3 lysC Aspartokinase Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Q1RGM9 1.03e-19 95 29 5 246 3 lysC Aspartokinase Rickettsia bellii (strain RML369-C)
Q58997 3.67e-18 90 23 10 360 3 hom Homoserine dehydrogenase Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
O58802 7.23e-18 89 25 11 358 1 PH1075 Homoserine dehydrogenase Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
F9VNG5 9.89e-18 88 25 12 353 1 hom Homoserine dehydrogenase Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
P0DXC5 6.97e-16 83 24 12 365 1 JFQ02_09240 NAD(+)-dependent homoserine dehydrogenase Pseudomonas canavaninivorans
P52985 6.98e-13 75 27 8 249 3 hom Homoserine dehydrogenase Lactococcus lactis subsp. cremoris
P19582 2.82e-12 73 25 12 276 1 hom Homoserine dehydrogenase Bacillus subtilis (strain 168)
Q9CGD8 4.1e-12 72 27 9 249 3 hom Homoserine dehydrogenase Lactococcus lactis subsp. lactis (strain IL1403)
A4VFY3 4.25e-11 69 23 17 484 1 ask Aspartate kinase Ask_Ect Stutzerimonas stutzeri (strain A1501)
P56429 3.25e-10 66 24 14 367 3 hom Homoserine dehydrogenase Helicobacter pylori (strain ATCC 700392 / 26695)
Q9ZL20 1.32e-09 64 27 10 254 3 hom Homoserine dehydrogenase Helicobacter pylori (strain J99 / ATCC 700824)
P46806 2.39e-09 64 25 7 224 3 hom Homoserine dehydrogenase Mycobacterium leprae (strain TN)
P52986 1.41e-08 61 32 3 116 3 hom Homoserine dehydrogenase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q5F8J4 5.74e-07 56 28 3 121 1 NGO_0779 Homoserine dehydrogenase Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
P29365 7.77e-07 56 27 4 140 3 hom Homoserine dehydrogenase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P9WPX1 4.61e-06 53 32 3 112 1 hom Homoserine dehydrogenase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WPX0 4.61e-06 53 32 3 112 3 hom Homoserine dehydrogenase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P63630 4.61e-06 53 32 3 112 3 hom Homoserine dehydrogenase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P08499 4.77e-06 53 25 9 253 1 hom Homoserine dehydrogenase Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
Q3SRH4 5.59e-06 52 26 9 232 3 pyrH Uridylate kinase Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)
O66929 0.000214 47 28 8 203 3 pyrH Uridylate kinase Aquifex aeolicus (strain VF5)
P74457 0.000341 47 27 10 225 3 pyrH Uridylate kinase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
P37144 0.000391 47 26 5 141 3 hom Homoserine dehydrogenase Methylobacillus glycogenes
A4FMD5 0.000433 46 28 8 201 3 pyrH Uridylate kinase Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)
A4YVG4 0.000633 45 29 2 94 3 pyrH Uridylate kinase Bradyrhizobium sp. (strain ORS 278)
A6VM31 0.000719 45 31 2 101 3 pyrH Uridylate kinase Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z)
Q136A6 0.000846 45 24 5 186 3 pyrH Uridylate kinase Rhodopseudomonas palustris (strain BisB5)
Q65R73 0.000863 45 32 4 115 3 pyrH Uridylate kinase Mannheimia succiniciproducens (strain KCTC 0769BP / MBEL55E)
Q1QMN5 0.000886 45 29 1 89 3 pyrH Uridylate kinase Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)
P43890 0.001 45 31 2 101 1 pyrH Uridylate kinase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS00005
Feature type CDS
Gene thrA
Product bifunctional aspartate kinase/homoserine dehydrogenase I
Location 337 - 2796 (strand: 1)
Length 2460 (nucleotides) / 819 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_1141
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00696 Amino acid kinase family
PF00742 Homoserine dehydrogenase
PF03447 Homoserine dehydrogenase, NAD binding domain
PF22468 ACT domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0527 Amino acid transport and metabolism (E) E Aspartate kinase

Kegg Ortholog Annotation(s)

Protein Sequence

MRVLKFGGTSVANAERVLNVADIAEKKREQGQVALVLSAPAKITNYLVAMIEKTAEGEEPLTQVREAEQIFANLLQGLRENQPGFDYQGLKDKVEREFAEIKHILHGISLLGQCPDSINAAMICRGEKLSIAIMESVLQARGYNVTVIDPVKNLLAQGHYLESTVDIPESTRRISALNIPKDHMILMAGFTAGNEKNELVVLGRNGSDYSAAVLAACLRAQCCEIWTDVDGVYTCDPRLVPDAHLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPEAPGTLIGDGQKDDSTPVKGITNLNNMAMINVSGPGMKGMVGMAARVFSVMSRAGISVVLITQSSSEYSISFCVPQKELIRAQKALSEEFYLELKDGVLDPLDIMNNVAIISVVGDGMRTLKGISARFFSALTRGNINIVAIAQGSSERSISAVITNDAATNAVRLCHQMLFNTNQIVEVFIVGVGGVGSALIEQIHRQQAWLKNKHIDLRVCGIANSRAMLTNMQGIDLDNWQQALQAAKEPFSFSQLIRLEKEYHFLNPVIVDCTSNEMIAQQYANFLQNGFNVVTPNKKANTMSMDYYHQIRQSAEASRRKFLYDTNVGAGLPVIENLQNLLNAGDELVQFNGILSGSLSYIFGQLDEGKSLSEATLSAKEKGFTEPDPRDDLSGMDVARKLLILAREAGYQLELSDIDVEPVLPSSFDSTGDVESFLNRLPQVDVEFDAKVEEAQKSAKVLRYVGIINEGKCQVKIMAVDANDPLFKVKNGENALAFYTRYYQPIPLVLRGYGAGNDVTAAGVFADVLRTLSWKLGV

Flanking regions ( +/- flanking 50bp)

CCGCATTGAGAAATGCGGGCTTTTTTTTGGCGAAAAATCAGGAGAGCTGTATGCGAGTGTTAAAATTTGGGGGAACTTCAGTTGCCAATGCAGAAAGGGTGCTGAATGTTGCTGATATCGCTGAGAAAAAACGAGAGCAGGGACAAGTCGCTCTGGTATTATCAGCACCTGCCAAGATAACGAATTACTTGGTGGCAATGATTGAAAAAACGGCAGAAGGAGAAGAACCTCTCACTCAAGTACGAGAAGCAGAGCAAATCTTCGCTAATCTATTGCAAGGTTTACGAGAAAATCAACCTGGTTTTGATTACCAAGGTTTAAAAGACAAAGTTGAGCGTGAGTTTGCTGAGATTAAACATATCCTGCATGGTATCTCCCTATTAGGGCAATGTCCTGATAGCATCAATGCTGCGATGATTTGTCGTGGTGAAAAGCTTTCGATTGCCATTATGGAGTCGGTGTTACAAGCTAGAGGATATAACGTTACCGTCATTGATCCGGTTAAAAATCTCCTTGCTCAAGGTCATTATCTCGAATCGACAGTGGATATTCCTGAATCAACTCGCCGTATTTCCGCCCTTAATATTCCGAAAGATCATATGATCTTGATGGCAGGTTTCACTGCCGGTAATGAAAAAAATGAGCTTGTGGTTCTCGGTCGTAATGGCTCAGATTATTCAGCCGCCGTATTAGCCGCGTGTTTACGTGCACAATGTTGTGAAATTTGGACGGATGTTGATGGTGTTTACACCTGTGATCCACGCCTCGTCCCAGATGCACACCTATTAAAAGGCATGTCCTATCAAGAGGCGATGGAACTTTCTTACTTTGGTGCCAAAGTCCTTCATCCACGCACTATTGCACCTATTGCTCAATTTCAAATCCCTTGTTTAATTAAAAATACGGGCAATCCAGAAGCACCGGGTACGTTAATAGGTGATGGTCAAAAAGATGACAGCACGCCGGTAAAAGGGATCACTAACCTGAATAATATGGCAATGATCAATGTATCAGGGCCAGGTATGAAGGGAATGGTGGGTATGGCGGCTCGTGTCTTTTCTGTGATGTCGCGTGCAGGAATATCGGTAGTATTAATTACTCAATCTTCATCTGAATACAGTATTAGCTTTTGTGTACCGCAAAAAGAGCTAATTAGAGCGCAAAAAGCACTGTCAGAAGAATTCTATCTAGAGTTAAAAGATGGCGTACTTGATCCGTTAGATATTATGAACAATGTTGCTATCATCTCGGTTGTCGGTGATGGTATGCGCACCCTTAAAGGGATCTCAGCCCGTTTCTTCTCTGCTTTAACTCGAGGCAATATTAATATTGTTGCTATTGCTCAAGGCTCTTCTGAACGCTCTATCTCTGCAGTTATTACTAATGATGCAGCGACGAATGCGGTGCGTTTATGTCACCAAATGCTCTTTAACACTAACCAAATCGTAGAAGTCTTTATTGTCGGTGTCGGTGGTGTTGGCAGCGCGCTAATCGAGCAGATCCATCGTCAACAAGCATGGCTAAAAAACAAACATATCGACCTACGTGTTTGTGGGATTGCCAATTCACGTGCGATGCTAACCAATATGCAAGGTATCGATTTAGATAATTGGCAACAAGCGCTACAAGCAGCTAAAGAGCCTTTTAGCTTTAGTCAGCTTATTCGCTTAGAAAAAGAGTACCACTTCCTCAATCCTGTGATTGTTGATTGCACTTCAAACGAAATGATTGCACAGCAATACGCCAATTTCTTACAAAATGGCTTTAACGTTGTTACGCCTAATAAAAAAGCCAATACGATGTCGATGGATTACTATCATCAAATTCGCCAATCAGCGGAAGCATCACGTCGTAAATTCTTATATGACACTAATGTTGGTGCGGGTTTACCTGTTATTGAAAACTTACAGAACTTGCTTAATGCTGGCGATGAGTTGGTGCAATTTAATGGTATTCTTTCTGGCTCACTCTCTTATATTTTTGGTCAGCTAGATGAAGGAAAAAGCTTGTCTGAAGCGACACTTTCTGCGAAAGAAAAAGGCTTTACAGAGCCAGATCCAAGAGATGATCTCTCGGGAATGGATGTTGCACGTAAACTGCTTATTCTCGCTCGTGAAGCGGGCTATCAATTAGAGTTGAGTGATATTGATGTAGAGCCTGTTTTACCTAGCTCATTTGATAGTACAGGTGATGTCGAGAGTTTCTTAAACCGCTTACCTCAAGTAGATGTTGAGTTTGATGCTAAAGTCGAAGAAGCCCAAAAGTCAGCGAAGGTATTACGTTATGTGGGGATCATCAATGAAGGGAAATGCCAAGTCAAAATAATGGCCGTTGATGCTAACGATCCTCTCTTTAAAGTAAAAAATGGTGAAAATGCGCTAGCTTTCTACACTCGCTACTATCAACCAATTCCTTTAGTTTTACGTGGATATGGTGCAGGAAATGATGTCACTGCTGCTGGGGTATTTGCAGATGTATTACGTACACTATCATGGAAATTAGGAGTTTAAAGGTGGTTAAAGTTTATGCACCGGCGTCAATTGGCAATGTGAGTGTCGGT