Homologs in group_3098

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5 homologs were identified in 5 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_19305 FBDBKF_19305 100.0 Morganella morganii S1 blaDHA-1 extended-spectrum class C beta-lactamase DHA-1
EHELCC_07590 EHELCC_07590 100.0 Morganella morganii S2 blaDHA-1 extended-spectrum class C beta-lactamase DHA-1
NLDBIP_07915 NLDBIP_07915 100.0 Morganella morganii S4 blaDHA-1 extended-spectrum class C beta-lactamase DHA-1
HKOGLL_03480 HKOGLL_03480 100.0 Morganella morganii S5 blaDHA-1 extended-spectrum class C beta-lactamase DHA-1
F4V73_RS12065 F4V73_RS12065 76.8 Morganella psychrotolerans ampC class C beta-lactamase

Distribution of the homologs in the orthogroup group_3098

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_3098

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P94958 0.0 768 98 0 379 3 ampC Beta-lactamase Morganella morganii
P00811 1.23e-154 443 57 1 376 1 ampC Beta-lactamase Escherichia coli (strain K12)
Q48434 5.59e-151 434 57 3 383 1 blaCMY-2 Beta-lactamase CMY-2 Klebsiella pneumoniae
O53044 2.31e-150 432 57 3 383 3 blaCMY-4 Beta-lactamase CMY-4 Klebsiella pneumoniae
P05193 3.11e-150 432 56 3 383 1 ampC Beta-lactamase Citrobacter freundii
P05364 3.67e-148 427 54 1 380 1 ampC Beta-lactamase Enterobacter cloacae
P45460 7.88e-132 385 53 4 388 3 ampC Beta-lactamase Yersinia enterocolitica
P85302 4.42e-127 372 51 4 360 1 ampC Beta-lactamase Pseudomonas fluorescens
P24735 7.6e-119 353 47 5 382 1 ampC Beta-lactamase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P71420 6.93e-104 314 44 6 378 1 blaCMY-1 Beta-lactamase CMY-1 Klebsiella pneumoniae
Q99QC1 1.68e-102 310 44 6 378 1 blaCMY-10 Beta-lactamase CMY-10 Klebsiella aerogenes
O05465 2.24e-98 301 42 4 379 1 ampC Beta-lactamase Psychrobacter immobilis
P18539 1.69e-89 277 40 6 381 3 ampC Beta-lactamase Serratia marcescens
Q48743 2.23e-79 251 36 5 377 3 None Beta-lactamase Lysobacter lactamgenus
O69773 2.72e-78 248 37 5 369 3 ampC Beta-lactamase Providencia stuartii
P0AD70 3.02e-16 82 24 12 386 1 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH Escherichia coli (strain K12)
P0AD71 3.02e-16 82 24 12 386 3 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH Escherichia coli O157:H7
Q8NUZ4 8.71e-14 76 26 9 244 3 flp Protein flp Staphylococcus aureus (strain MW2)
Q6G6M9 9.88e-14 75 26 9 244 3 flp Protein flp Staphylococcus aureus (strain MSSA476)
Q5HDB2 1.9e-13 75 25 9 244 4 flp Protein flp Staphylococcus aureus (strain COL)
Q7A3Q5 1.91e-13 75 25 9 244 1 flp Protein flp Staphylococcus aureus (strain N315)
Q99RJ0 1.91e-13 75 25 9 244 3 flp Protein flp Staphylococcus aureus (strain Mu50 / ATCC 700699)
Q9KJ74 2.38e-13 74 25 9 244 4 flp Protein flp Staphylococcus aureus
Q2FVH6 2.38e-13 74 25 9 244 4 flp Protein flp Staphylococcus aureus (strain NCTC 8325 / PS 47)
Q6GDZ1 2.38e-13 74 25 9 244 3 flp Protein flp Staphylococcus aureus (strain MRSA252)
P32959 2.28e-12 71 22 12 315 1 pbpE Penicillin-binding protein 4* Bacillus subtilis (strain 168)
P9WLZ3 5.98e-10 63 25 6 235 1 Rv1367c Protein Rv1367c Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WLZ2 5.98e-10 63 25 6 235 4 MT1414 Uncharacterized protein MT1414 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Q06317 8.12e-09 60 23 7 281 3 pbp Penicillin-binding protein 4 Amycolatopsis lactamdurans
Q9KX40 1.44e-06 53 26 7 231 1 estB Esterase EstB Burkholderia gladioli
O31773 5.02e-06 51 25 3 205 2 pbpX Putative penicillin-binding protein PbpX Bacillus subtilis (strain 168)
P15555 5.87e-06 51 26 5 196 1 None D-alanyl-D-alanine carboxypeptidase Streptomyces sp. (strain R61)
Q6GI27 3.31e-05 49 26 3 167 3 fmtA Teichoic acid D-alanine hydrolase Staphylococcus aureus (strain MRSA252)
A6WYS5 5.69e-05 48 26 10 267 3 dap D-aminopeptidase Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37)
Q54VJ1 9.45e-05 48 27 6 155 3 DDB_G0280307 Beta-lactamase-like protein 2 Dictyostelium discoideum
Q5HH27 0.000201 46 26 3 167 2 fmtA Teichoic acid D-alanine hydrolase Staphylococcus aureus (strain COL)
Q2FZK3 0.000201 46 26 3 167 2 fmtA Teichoic acid D-alanine hydrolase Staphylococcus aureus (strain NCTC 8325 / PS 47)
Q7A185 0.000205 46 27 3 151 3 fmtA Teichoic acid D-alanine hydrolase Staphylococcus aureus (strain MW2)
O50608 0.000205 46 27 3 151 1 fmtA Teichoic acid D-alanine hydrolase Staphylococcus aureus
Q6GAF6 0.000205 46 27 3 151 3 fmtA Teichoic acid D-alanine hydrolase Staphylococcus aureus (strain MSSA476)
Q7A6A2 0.000205 46 27 3 151 1 fmtA Teichoic acid D-alanine hydrolase Staphylococcus aureus (strain N315)
Q7A2T0 0.000205 46 27 3 151 1 fmtA Teichoic acid D-alanine hydrolase Staphylococcus aureus (strain Mu50 / ATCC 700699)
P83095 0.000701 45 29 2 101 1 LACTB Serine beta-lactamase-like protein LACTB, mitochondrial Bos taurus

  • Number of RefSeq hits:

General

Source Morganella morganii S3
Locus tag LHKJJB_07450
Feature type CDS
Gene blaDHA-1
Product extended-spectrum class C beta-lactamase DHA-1
Location 218524 - 219663 (strand: 1)
Length 1140 (nucleotides) / 379 (amino acids)

Contig

Accession ZDB_363
Length 233386 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_3098
Orthogroup size 6
N. genomes 6

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Genomic region

Domains

PF00144 Beta-lactamase

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG1680 Defense mechanisms (V) V CubicO group peptidase, beta-lactamase class C family

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K19100 beta-lactamase class C DHA [EC:3.5.2.6] beta-Lactam resistance -

AMR gene Annotation(s)

Gene Description Scope Type Class Subclass HMM
blaDHA-1 extended-spectrum class C beta-lactamase DHA-1 core AMR BETA-LACTAM CEPHALOSPORIN NF012102 

Protein Sequence

MKKSLSATLISALLAFSAPGFSAADNVAAVVDSTIKPLMAQQDIPGMAVAVSVKGKPYYFNYGFADIQAKQPVTENTLFELGSVSKTFTGVLGAVSVAKKEMALNDPAAKYQPELALPQWKGITLLDLATYTAGGLPLQVPDAVKSRADLLNFYQQWQPSRKPGDMRLYANSSIGLFGALTANAAGMPYEQLLTARILAPLGLSHTFITVPESAQSQYAYGYKNKKPVRVSPGQLDAESYGVKSASKDMLRWAEMNMEPSRAGNADLEMAMYLAQTRYYKTAAINQGLGWEMYDWPQQKDMIINGVTNEVALQPHPVTDNQVQPYNRASWVHKTGATTGFGAYVAFIPEKQVAIVILANKNYPNTERVKAAQAILSALE

Flanking regions ( +/- flanking 50bp)

GAATCTGACGATACTTGCCGCCGTTACTCACACACGGAAGGTTAATTCTGATGAAAAAATCGTTATCTGCAACACTGATTTCCGCTCTGCTGGCGTTTTCCGCCCCGGGGTTTTCTGCCGCTGATAATGTCGCGGCGGTGGTGGACAGCACCATTAAACCGCTGATGGCACAGCAGGATATTCCCGGGATGGCGGTTGCCGTCTCCGTAAAGGGTAAGCCCTATTATTTCAATTATGGTTTTGCCGATATTCAGGCAAAACAGCCGGTCACTGAAAATACACTATTTGAGCTCGGATCTGTAAGTAAAACTTTCACAGGTGTGCTGGGTGCGGTTTCTGTGGCGAAAAAAGAGATGGCGCTGAATGATCCGGCGGCAAAATACCAGCCGGAGCTGGCTCTGCCGCAGTGGAAGGGGATCACATTGCTGGATCTGGCTACCTATACCGCAGGCGGACTGCCGTTACAGGTGCCGGATGCGGTAAAAAGCCGTGCGGATCTGCTGAATTTCTATCAGCAGTGGCAGCCGTCCCGGAAACCGGGCGATATGCGTCTGTATGCAAACAGCAGTATCGGCCTGTTTGGTGCTCTGACCGCAAACGCGGCGGGGATGCCGTATGAGCAGTTGCTGACTGCACGGATCCTGGCACCGCTGGGGTTATCTCACACCTTTATTACTGTGCCGGAAAGTGCGCAAAGCCAGTATGCGTACGGTTATAAAAACAAAAAACCGGTCCGCGTGTCGCCGGGACAGCTTGATGCGGAATCTTACGGCGTGAAATCCGCCTCAAAAGATATGCTGCGCTGGGCGGAAATGAATATGGAGCCGTCACGGGCCGGTAATGCGGATCTGGAAATGGCAATGTATCTCGCCCAGACCCGCTACTATAAAACCGCCGCGATTAACCAGGGGCTGGGCTGGGAAATGTATGACTGGCCGCAGCAGAAAGATATGATCATTAACGGTGTGACCAACGAGGTCGCATTGCAGCCGCATCCGGTAACAGACAACCAGGTTCAGCCGTATAACCGTGCTTCCTGGGTGCATAAAACGGGCGCAACAACTGGTTTCGGCGCCTATGTCGCCTTTATTCCGGAAAAACAGGTGGCGATTGTGATTCTGGCGAATAAAAACTACCCGAATACCGAAAGAGTCAAAGCTGCACAGGCTATTTTGAGTGCACTGGAATAATTTTTTTCCTGAACAGGCCCCTGCGGATACGCCGGGGCCGTAATTTAAGA