Homologs in group_2406

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_19280 FBDBKF_19280 100.0 Morganella morganii S1 hybC hydrogenase 2 large subunit
EHELCC_07565 EHELCC_07565 100.0 Morganella morganii S2 hybC hydrogenase 2 large subunit
NLDBIP_07890 NLDBIP_07890 100.0 Morganella morganii S4 hybC hydrogenase 2 large subunit
HKOGLL_03505 HKOGLL_03505 100.0 Morganella morganii S5 hybC hydrogenase 2 large subunit
F4V73_RS12040 F4V73_RS12040 92.8 Morganella psychrotolerans hybC hydrogenase 2 large subunit
PMI_RS00165 PMI_RS00165 70.0 Proteus mirabilis HI4320 hybC hydrogenase 2 large subunit

Distribution of the homologs in the orthogroup group_2406

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2406

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0ACE2 0.0 999 82 0 567 3 hybC Hydrogenase-2 large chain Shigella flexneri
P0ACE0 0.0 999 82 0 567 1 hybC Hydrogenase-2 large chain Escherichia coli (strain K12)
P0ACE1 0.0 999 82 0 567 3 hybC Hydrogenase-2 large chain Escherichia coli O157:H7
P12636 1.28e-168 494 45 11 593 3 hupB Uptake hydrogenase large subunit Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
P18636 8.31e-168 492 45 13 591 3 hupB Uptake hydrogenase large subunit Rhizobium leguminosarum bv. viciae
P15284 1.52e-164 484 44 16 595 3 hupB Uptake hydrogenase large subunit Rhodobacter capsulatus
P0ACD9 5.21e-163 480 43 12 591 3 hyaB Hydrogenase-1 large chain Shigella flexneri
P0ACD8 5.21e-163 480 43 12 591 1 hyaB Hydrogenase-1 large chain Escherichia coli (strain K12)
P12944 2.68e-162 476 44 11 568 1 hydB Periplasmic [NiFe] hydrogenase large subunit Megalodesulfovibrio gigas
P21949 1.01e-160 474 44 13 594 3 hoxG Uptake hydrogenase large subunit Azotobacter vinelandii
P31891 5.82e-159 470 44 15 607 1 hoxG Uptake hydrogenase large subunit Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)
P21852 1.82e-157 465 44 12 570 1 hydB Periplasmic [NiFe] hydrogenase large subunit Nitratidesulfovibrio vulgaris (strain DSM 19637 / Miyazaki F)
Q46046 5.08e-157 464 41 11 591 3 hyaB Hydrogenase-1 large chain Citrobacter freundii
P17632 3.5e-154 458 43 15 607 3 hupB Uptake hydrogenase large subunit Rubrivivax gelatinosus
P18188 5.71e-153 453 43 10 571 1 hydB Periplasmic [NiFe] hydrogenase large subunit Solidesulfovibrio fructosivorans
O33406 1.18e-149 446 42 13 592 1 hoxL Uptake hydrogenase large subunit Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5)
P33374 2.94e-145 435 41 13 611 3 hupL Uptake hydrogenase large subunit Alcaligenes hydrogenophilus
P31883 6.4e-144 430 40 10 588 1 hydB Quinone-reactive Ni/Fe-hydrogenase large chain Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / CCUG 13145 / JCM 31913 / LMG 7466 / NCTC 11488 / FDC 602W)
P18191 1.16e-139 420 41 11 591 3 hupL Uptake hydrogenase large subunit Azotobacter chroococcum mcd 1
P13065 2.48e-89 288 33 13 566 1 None Periplasmic [NiFeSe] hydrogenase large subunit Desulfomicrobium baculatum
Q50249 1.25e-52 192 28 22 631 2 vhoA F420 non-reducing hydrogenase I large subunit Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
F1SVF8 9.96e-52 189 28 22 631 2 vhtA F420 non-reducing hydrogenase II large subunit Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
P19496 9.09e-23 104 47 3 119 1 frhA Coenzyme F420 hydrogenase subunit alpha Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
P19496 1.13e-08 61 23 15 377 1 frhA Coenzyme F420 hydrogenase subunit alpha Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Q49179 1.03e-21 102 24 22 565 3 mvhA F420-non-reducing hydrogenase subunit A Methanothermus fervidus
Q00404 4.32e-17 87 36 1 115 2 vhcA F420-non-reducing hydrogenase vhc subunit A Methanococcus voltae
Q00404 0.001 45 32 2 86 2 vhcA F420-non-reducing hydrogenase vhc subunit A Methanococcus voltae
Q00407 1.84e-16 85 38 2 126 3 vhuA F420-non-reducing hydrogenase vhu subunit A Methanococcus voltae
Q58592 5.76e-16 84 29 4 178 3 vhuA F420-non-reducing hydrogenase vhu subunit A Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
P80489 5.14e-14 78 35 2 109 1 frhA Coenzyme F420 hydrogenase subunit alpha Methanosarcina barkeri (strain Fusaro / DSM 804)
P80489 0.000104 48 24 11 249 1 frhA Coenzyme F420 hydrogenase subunit alpha Methanosarcina barkeri (strain Fusaro / DSM 804)
Q60338 1.24e-13 76 40 2 97 3 frhA Coenzyme F420 hydrogenase subunit alpha Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q60338 0.000803 45 29 5 100 3 frhA Coenzyme F420 hydrogenase subunit alpha Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q50783 1.48e-13 76 36 2 118 3 mvhA F420-non-reducing hydrogenase subunit A Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
P60227 1.61e-13 76 36 2 118 1 mvhA F420-non-reducing hydrogenase subunit A Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)
P60227 0.000361 47 24 19 379 1 mvhA F420-non-reducing hydrogenase subunit A Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)
P84625 1.31e-11 70 32 2 128 1 mvhA F420-non-reducing hydrogenase iron-sulfur subunit A Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)
Q00390 7.53e-11 67 32 3 119 3 frhA Coenzyme F420 hydrogenase subunit alpha Methanococcus voltae
P22320 2.42e-10 66 35 3 113 1 hoxH NAD-reducing hydrogenase HoxS subunit beta Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)
Q58433 4.04e-09 62 32 3 107 3 MJ1027 Uncharacterized protein MJ1027 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
P77329 1.77e-08 60 32 2 95 1 hyfG Hydrogenase-4 component G Escherichia coli (strain K12)
P16431 5.66e-08 59 31 2 95 1 hycE Formate hydrogenlyase subunit 5 Escherichia coli (strain K12)
E7FI44 6.23e-08 58 30 1 121 1 hydA Sulfhydrogenase 1 subunit alpha Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
E7FHC4 8.78e-08 58 35 1 93 1 shyA Sulfhydrogenase 2 subunit alpha Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
E7FHC4 9.1e-05 48 32 3 88 1 shyA Sulfhydrogenase 2 subunit alpha Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Q57935 1.4e-06 54 27 1 91 3 MJ0515 Uncharacterized protein MJ0515 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
P40597 1.15e-05 51 32 1 85 4 hoxV Hydrogenase expression/formation protein HoxV Azotobacter vinelandii
P31878 1.21e-05 51 32 1 85 3 hupK Hydrogenase expression/formation protein HupK Azotobacter vinelandii
Q43959 1.39e-05 51 28 3 103 3 hupV Hydrogenase expression/formation protein HupV Azotobacter chroococcum mcd 1
Q8U0Z6 4.86e-05 49 29 0 85 1 mbhL Membrane-bound hydrogenase subunit alpha Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
B2UV27 0.000122 48 31 2 102 3 nuoD NADH-quinone oxidoreductase subunit D Helicobacter pylori (strain Shi470)
Q9ZJW4 0.000167 47 31 2 102 3 nuoD NADH-quinone oxidoreductase subunit D Helicobacter pylori (strain J99 / ATCC 700824)
B6JNA3 0.000167 47 31 2 102 3 nuoD NADH-quinone oxidoreductase subunit D Helicobacter pylori (strain P12)
B5Z8Q8 0.000173 47 31 2 102 3 nuoD NADH-quinone oxidoreductase subunit D Helicobacter pylori (strain G27)
Q1CRZ8 0.000177 47 31 2 102 3 nuoD NADH-quinone oxidoreductase subunit D Helicobacter pylori (strain HPAG1)
O25853 0.000184 47 31 2 102 3 nuoD NADH-quinone oxidoreductase subunit D Helicobacter pylori (strain ATCC 700392 / 26695)
Q58137 0.000647 45 30 1 97 4 MJ0727 Uncharacterized protein MJ0727 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q17Z55 0.000685 45 30 2 102 3 nuoD NADH-quinone oxidoreductase subunit D Helicobacter acinonychis (strain Sheeba)

  • Number of RefSeq hits:

General

Source Morganella morganii S3
Locus tag LHKJJB_07425
Feature type CDS
Gene hybC
Product hydrogenase 2 large subunit
Location 214519 - 216222 (strand: 1)
Length 1704 (nucleotides) / 567 (amino acids)

Contig

Accession ZDB_363
Length 233386 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_2406
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00374 Nickel-dependent hydrogenase

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0374 Energy production and conversion (C) C Ni,Fe-hydrogenase I large subunit

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K06281 hydrogenase large subunit [EC:1.12.99.6] Nitrotoluene degradation
Microbial metabolism in diverse environments
Two-component system		 -

Protein Sequence

MSQRITIDPVTRIEGHLRIDCEIGDGVVTKAWASGTMWRGMEKIVKGKDPRDAWMILQRICGVCTTTHALASVRAVENALNLDVPVNAQYIRNIILAAHTTHDHIVHFYQLSALDWVDITSALKADPAKASAMLNGVSDWPLNSTQEFVRVQDKIKALVESGQLGIFANGYWGHPAMQLPPEVNLIAVAHYLQALECQRDANRIVALLGGKTPHIQNLAVGGVANPINLDGIGVLNLERLMYIKSFIDKLNDFVEQVYKIDTAVIAAFYPQWFETGQGAVNYLSTPEFPTDGKNGSFLFPGGYIENADLATFRPIDSQTDAFLLEGIQESSPHSWYQDEAPQKPWEGTTEPKYTGWDPDGKYSWVKSPTLYGKTVEVGPLANMFCKLAAKHPGTAEKLNEIIAVYQTLTGNTPEVKQLHSTLGRIIGRTVHCCELQAVLQNQYAALIANIGTGDHITYVKPEFPATGVIKGVGFLEAPRGMLSHWVVIKDGVIENYQAVVPSTWNCGPRNHDNVAGPYEQSLVGLKIADPEKPLEVVRTIHSFDPCMACAVHIVDVDGRETVSVKVL

Flanking regions ( +/- flanking 50bp)

CCTGCAGTCAATAAAACCGCAGCTCACCCTTATCATGAGGCAAGCAAGTCATGAGCCAGAGAATTACGATTGATCCGGTTACCCGTATCGAAGGACATTTACGCATTGACTGTGAAATCGGCGATGGTGTGGTCACCAAAGCCTGGGCGTCAGGCACCATGTGGCGCGGAATGGAAAAAATCGTCAAAGGGAAAGATCCGCGTGATGCGTGGATGATCCTCCAGCGCATCTGCGGCGTCTGCACCACCACACACGCGCTGGCATCGGTGCGTGCCGTGGAAAATGCCCTGAACCTGGATGTGCCGGTTAATGCGCAGTATATCCGCAATATCATTCTGGCGGCACACACCACCCATGACCATATCGTCCACTTTTATCAGCTCTCCGCGCTGGACTGGGTGGATATCACCTCCGCGCTGAAAGCGGATCCGGCAAAAGCCTCTGCCATGCTGAACGGCGTTTCTGACTGGCCGCTCAACAGCACGCAGGAATTCGTCAGAGTGCAGGATAAAATCAAAGCACTGGTGGAAAGCGGGCAACTGGGGATTTTTGCCAACGGCTACTGGGGACACCCGGCGATGCAGTTGCCGCCGGAAGTGAACCTGATTGCCGTCGCACACTATTTACAGGCGCTGGAATGCCAGCGCGATGCTAACCGTATTGTGGCGCTGCTGGGTGGCAAAACGCCGCACATTCAGAACCTGGCGGTCGGCGGCGTGGCAAACCCGATTAACCTCGACGGTATCGGTGTGCTGAACCTGGAACGCCTGATGTATATCAAATCATTTATCGACAAGCTGAATGATTTCGTTGAGCAGGTTTATAAAATTGATACTGCGGTCATTGCTGCATTTTACCCGCAGTGGTTTGAAACCGGGCAGGGCGCAGTGAACTACCTGAGCACCCCGGAATTCCCGACCGACGGCAAAAACGGCAGTTTCCTGTTCCCGGGCGGCTACATTGAAAACGCTGACTTAGCGACTTTCCGCCCGATCGATTCCCAGACGGATGCTTTCCTGCTGGAAGGGATTCAGGAAAGTTCTCCGCACTCCTGGTATCAGGATGAAGCGCCGCAGAAACCGTGGGAAGGCACAACTGAGCCGAAATACACCGGCTGGGATCCGGACGGTAAATACTCGTGGGTGAAATCGCCGACTCTGTACGGCAAAACCGTGGAAGTCGGCCCGCTGGCCAATATGTTCTGTAAACTGGCGGCGAAACACCCCGGCACAGCCGAAAAACTGAATGAAATTATCGCTGTTTATCAGACCCTGACCGGCAACACCCCGGAGGTAAAACAGCTGCATTCCACACTCGGGCGGATTATCGGCCGTACGGTGCACTGCTGTGAATTACAGGCGGTGTTGCAGAACCAGTATGCCGCGCTGATCGCCAATATCGGTACCGGGGATCATATCACTTATGTGAAACCGGAATTCCCGGCCACCGGCGTGATAAAAGGCGTGGGTTTCCTGGAAGCACCACGCGGCATGTTATCGCACTGGGTGGTGATCAAAGACGGCGTGATTGAGAACTATCAGGCGGTGGTACCGTCCACCTGGAACTGCGGGCCGCGCAATCACGATAATGTGGCGGGGCCGTATGAGCAGTCGCTGGTCGGGCTGAAAATTGCTGATCCGGAAAAACCGCTGGAAGTGGTGCGCACTATCCACTCATTCGACCCGTGTATGGCATGTGCGGTTCATATTGTTGATGTTGATGGCCGTGAAACGGTATCAGTGAAGGTGCTGTAATGCGGATTCTGGTATTAGGTGTCGGCAATATTCTGCTGACTGACGAAGCT