Homologs in group_1399

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_08635 FBDBKF_08635 91.5 Morganella morganii S1 folP dihydropteroate synthase
EHELCC_12890 EHELCC_12890 91.5 Morganella morganii S2 folP dihydropteroate synthase
NLDBIP_13230 NLDBIP_13230 91.5 Morganella morganii S4 folP dihydropteroate synthase
LHKJJB_13325 LHKJJB_13325 91.5 Morganella morganii S3 folP dihydropteroate synthase
HKOGLL_11705 HKOGLL_11705 91.5 Morganella morganii S5 folP dihydropteroate synthase
PMI_RS16990 PMI_RS16990 72.5 Proteus mirabilis HI4320 folP dihydropteroate synthase

Distribution of the homologs in the orthogroup group_1399

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1399

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0AC15 3.47e-143 406 69 0 282 3 folP Dihydropteroate synthase Shigella flexneri
P0AC13 3.47e-143 406 69 0 282 1 folP Dihydropteroate synthase Escherichia coli (strain K12)
P0AC14 3.47e-143 406 69 0 282 3 folP Dihydropteroate synthase Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P43776 9.76e-115 334 58 0 272 3 folP-A Dihydropteroate synthase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P73248 5.93e-74 231 47 2 257 3 folP Dihydropteroate synthase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q51161 2.88e-72 226 50 7 269 3 folP Dihydropteroate synthase Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
P28822 4.94e-71 223 48 2 256 3 sul Dihydropteroate synthase Bacillus subtilis (strain 168)
Q9JT70 3.14e-70 221 50 6 267 3 folP Dihydropteroate synthase Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)
P57696 1.65e-69 219 49 6 267 3 folP Dihydropteroate synthase Neisseria meningitidis serogroup C
P0DB09 6.62e-64 204 45 3 247 3 folP Dihydropteroate synthase Streptococcus pyogenes serotype M3 (strain SSI-1)
P0DB08 6.62e-64 204 45 3 247 3 folP Dihydropteroate synthase Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
Q05621 2.16e-63 203 43 3 256 3 Cbei_0206 Dihydropteroate synthase Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)
Q5XCA8 2.23e-63 203 45 3 247 1 folP Dihydropteroate synthase Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
Q8P152 2.71e-63 202 45 3 247 3 folP Dihydropteroate synthase Streptococcus pyogenes serotype M18 (strain MGAS8232)
P0C0G1 2.86e-63 202 45 3 247 3 folP Dihydropteroate synthase Streptococcus pyogenes serotype M1
P0C0G0 1.21e-62 201 44 3 256 3 folP Dihydropteroate synthase Streptococcus pyogenes
P0C0X1 2.38e-62 201 41 5 274 1 folP1 Dihydropteroate synthase Mycobacterium leprae (strain TN)
Q9HS44 3.53e-58 202 50 2 257 3 folP Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
P9WND1 2.46e-54 180 41 4 270 1 folP1 Dihydropteroate synthase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WND0 2.46e-54 180 41 4 270 3 folP1 Dihydropteroate synthase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P0A579 2.46e-54 180 41 4 270 3 folP1 Dihydropteroate synthase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
D4GW05 1.88e-53 189 49 2 257 3 folCP Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)
Q1ENB6 7.65e-53 182 40 7 280 1 CytHPPK/DHPS Folate synthesis bifunctional protein Arabidopsis thaliana
Q4LB35 6.36e-52 184 41 7 265 1 fol1 Folic acid synthesis protein fol1 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
O04862 2.07e-51 179 40 6 271 1 MitHPPK/DHPS Folate synthesis bifunctional protein, mitochondrial Pisum sativum
Q59919 2.53e-51 172 41 5 256 3 folP Dihydropteroate synthase Staphylococcus haemolyticus
Q9SZV3 2.75e-51 179 40 6 272 2 MitHPPK/DHPS Folate synthesis bifunctional protein, mitochondrial Arabidopsis thaliana
P29251 1.88e-50 179 38 6 267 1 fol1 Folic acid synthesis protein fol1 Pneumocystis carinii
Q5HRP0 8.64e-45 155 40 6 252 3 folP Dihydropteroate synthase Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
Q8NXZ2 1.58e-44 154 40 5 252 3 folP Dihydropteroate synthase Staphylococcus aureus (strain MW2)
O05701 3.57e-44 154 40 5 252 1 folP Dihydropteroate synthase Staphylococcus aureus
Q6GJF7 3.57e-44 154 40 5 252 3 folP Dihydropteroate synthase Staphylococcus aureus (strain MRSA252)
P64142 4.72e-44 153 40 5 252 3 folP Dihydropteroate synthase Staphylococcus aureus (strain N315)
P64141 4.72e-44 153 40 5 252 1 folP Dihydropteroate synthase Staphylococcus aureus (strain Mu50 / ATCC 700699)
Q6GBX4 6.36e-44 153 40 5 252 3 folP Dihydropteroate synthase Staphylococcus aureus (strain MSSA476)
Q5HIG1 1.6e-43 152 40 5 252 3 folP Dihydropteroate synthase Staphylococcus aureus (strain COL)
Q8CMT7 2.26e-43 152 39 6 252 3 folP Dihydropteroate synthase Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
P05382 4.6e-43 152 39 7 294 1 sulA Dihydropteroate synthase Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
P59655 3.78e-42 150 37 5 293 1 sulA Dihydropteroate synthase Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
O25830 3.84e-36 135 30 5 262 1 folP Bifunctional dihydropteroate synthase/dihydropteroate reductase Helicobacter pylori (strain ATCC 700392 / 26695)
P0AC12 7.39e-36 132 33 3 260 3 sulII Dihydropteroate synthase type-2 Shigella flexneri
P0AC11 7.39e-36 132 33 3 260 1 sulII Dihydropteroate synthase type-2 Escherichia coli
P53848 4.91e-32 128 27 8 331 1 FOL1 Folic acid synthesis protein FOL1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P0C0X2 1.5e-31 121 36 4 259 3 folP2 Inactive dihydropteroate synthase 2 Mycobacterium leprae (strain TN)
P82602 6.92e-30 120 33 9 263 3 folKP Folate synthesis bifunctional protein Chlamydia muridarum (strain MoPn / Nigg)
Q9Z7E8 2.06e-29 119 30 5 260 3 folKP Folate synthesis bifunctional protein Chlamydia pneumoniae
Q821E2 1.13e-28 116 30 6 255 3 folKP Folate synthesis bifunctional protein Chlamydia caviae (strain ATCC VR-813 / DSM 19441 / 03DC25 / GPIC)
P0C003 1.11e-27 110 30 5 268 3 sulI Dihydropteroate synthase type-1 Pseudomonas aeruginosa
P0C002 1.11e-27 110 30 5 268 1 sulI Dihydropteroate synthase type-1 Escherichia coli
P0C004 1.11e-27 110 30 5 268 3 sulI Dihydropteroate synthase type-1 Corynebacterium glutamicum
Q49184 1.23e-27 110 30 5 268 3 sulI Dihydropteroate synthase type-1 Mycolicibacterium fortuitum
O84619 2.53e-24 104 31 9 261 3 folKP Folate synthesis bifunctional protein Chlamydia trachomatis serovar D (strain ATCC VR-885 / DSM 19411 / UW-3/Cx)
Q54YD9 3.41e-23 102 43 4 137 3 fol1 Folic acid synthesis protein FOL1 Dictyostelium discoideum
Q54YD9 2.34e-16 82 36 2 116 3 fol1 Folic acid synthesis protein FOL1 Dictyostelium discoideum
P9WNC9 1.42e-20 92 32 4 259 1 folP2 Inactive dihydropteroate synthase 2 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WNC8 1.42e-20 92 32 4 259 3 folP2 Inactive dihydropteroate synthase 2 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P64140 1.42e-20 92 32 4 259 3 folP2 Inactive dihydropteroate synthase 2 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)

  • Number of RefSeq hits:

General

Source Morganella psychrotolerans
Locus tag F4V73_RS09860
Feature type CDS
Gene folP
Product dihydropteroate synthase
Location 76267 - 77115 (strand: 1)
Length 849 (nucleotides) / 282 (amino acids)

Contig

Accession term accessions NZ_VXKB01000002 accessions NZ_VXKB01000000 Name: value, dtype: object
Length 573139 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_1399
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00809 Pterin binding enzyme

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0294 Coenzyme transport and metabolism (H) H Dihydropteroate synthase

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K00796 dihydropteroate synthase [EC:2.5.1.15] Folate biosynthesis
Metabolic pathways
Biosynthesis of cofactors
Tetrahydrofolate biosynthesis, GTP => THF

Protein Sequence

MKLTARGQTLSLATPQVMGILNVTPDSFSDGGTHNTPVQALAHARRMIMEGAAIIDIGGESTRPGAAEVSPEQEAERVIPVVEAIARESDVWISVDTSKALVIREAAKAGAHIINDIRSLTEPGALQAAAVSGLPVCVMHMQGEPRTMQQAPHYADVVRDVYAYLDAQVARCMAAGIEKNHIILDPGFGFGKSLAHNYQLLDKLDEFHKLGLPVLAGMSRKSMIGQLMDLPPDERVAGSVACAVIAAMKGAHIIRVHDVKETVQAMKVVEATRLAKEKNDNE

Flanking regions ( +/- flanking 50bp)

GCATTACAATCTGTTTATGTATTGATTAAAAATAGTAAGAAGGCCGGATTATGAAACTTACCGCACGCGGTCAGACTCTCTCCCTGGCAACACCACAGGTGATGGGGATCCTCAATGTGACTCCTGATTCATTCTCTGACGGCGGCACACACAACACGCCTGTACAAGCACTTGCACATGCCCGCCGGATGATTATGGAAGGTGCTGCAATTATTGATATCGGTGGTGAATCAACCCGCCCGGGAGCGGCAGAAGTCAGCCCTGAGCAGGAAGCAGAACGCGTAATACCTGTTGTTGAAGCGATTGCCCGCGAATCTGATGTCTGGATTTCAGTCGATACCTCTAAAGCACTGGTTATCCGTGAAGCCGCGAAAGCCGGTGCGCATATTATCAATGATATCCGCTCATTAACAGAGCCCGGAGCCCTTCAGGCAGCAGCTGTAAGCGGTTTGCCTGTCTGTGTCATGCACATGCAGGGCGAACCCCGTACAATGCAGCAGGCACCGCATTACGCGGATGTGGTGCGTGATGTTTATGCGTATCTTGATGCACAGGTGGCACGCTGCATGGCCGCCGGTATTGAAAAAAATCACATAATTCTCGATCCGGGCTTCGGTTTTGGTAAATCTTTAGCGCATAATTATCAACTGTTAGATAAATTAGACGAATTTCATAAACTGGGATTACCGGTTCTCGCCGGAATGTCACGTAAATCAATGATTGGTCAGCTGATGGATCTTCCCCCTGATGAACGGGTTGCCGGCAGTGTGGCTTGTGCGGTGATTGCCGCAATGAAAGGGGCACACATTATTCGTGTCCATGATGTAAAAGAGACTGTTCAGGCCATGAAAGTGGTGGAAGCGACCCGTTTAGCAAAGGAAAAAAACGACAATGAGTGAGCGCAAATATTTTGGTACTGATGGTATCCGCGGAAAAGTGGGCGACAGCC