Homologs in group_2554

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5 homologs were identified in 5 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_02600 FBDBKF_02600 100.0 Morganella morganii S1 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
NLDBIP_00390 NLDBIP_00390 100.0 Morganella morganii S4 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
LHKJJB_01645 LHKJJB_01645 100.0 Morganella morganii S3 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
HKOGLL_01685 HKOGLL_01685 100.0 Morganella morganii S5 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
F4V73_RS05040 F4V73_RS05040 67.7 Morganella psychrotolerans - efflux RND transporter periplasmic adaptor subunit

Distribution of the homologs in the orthogroup group_2554

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2554

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P94176 4.21e-07 55 25 9 288 3 czcB Cation efflux system protein CzcB Alcaligenes sp. (strain CT14)
P13510 3.26e-06 52 25 9 288 1 czcB Cobalt-zinc-cadmium resistance protein CzcB Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)
B4T9U0 5.01e-06 51 30 3 140 3 mdtA Multidrug resistance protein MdtA Salmonella heidelberg (strain SL476)
Q8Z5F8 5.52e-06 51 30 3 140 3 mdtA Multidrug resistance protein MdtA Salmonella typhi
C0Q1F4 5.52e-06 51 30 3 140 3 mdtA Multidrug resistance protein MdtA Salmonella paratyphi C (strain RKS4594)
Q8ZNQ3 6.26e-06 51 30 3 140 3 mdtA Multidrug resistance protein MdtA Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q88F89 3.11e-05 49 22 9 353 1 pvdR Pyoverdine export membrane fusion protein PvdR Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Q83KI5 3.51e-05 48 29 3 147 3 mdtA Putative multidrug resistance protein MdtA Shigella flexneri
B7L9U7 4.12e-05 48 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain 55989 / EAEC)
B7ME86 6.96e-05 48 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O45:K1 (strain S88 / ExPEC)
P76397 7.08e-05 48 29 3 144 2 mdtA Multidrug resistance protein MdtA Escherichia coli (strain K12)
A8A1U6 7.08e-05 48 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O9:H4 (strain HS)
B1X7H0 7.08e-05 48 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain K12 / DH10B)
C4ZSG2 7.08e-05 48 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain K12 / MC4100 / BW2952)
B7UTB2 7.08e-05 48 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Q7N3E3 7.69e-05 48 29 3 140 3 mdtA Multidrug resistance protein MdtA Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
A7ZNP7 0.00011 47 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O139:H28 (strain E24377A / ETEC)
Q8CVX8 0.000115 47 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
B7MWY7 0.000115 47 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O81 (strain ED1a)
B7M457 0.000117 47 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O8 (strain IAI1)
Q0TG16 0.000136 47 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O6:K15:H31 (strain 536 / UPEC)
A4WCC0 0.000152 47 23 9 341 3 mdtA Multidrug resistance protein MdtA Enterobacter sp. (strain 638)
B7LV38 0.000156 47 29 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)
B7NCB0 0.000249 46 28 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
B7NQB2 0.000405 45 28 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O7:K1 (strain IAI39 / ExPEC)
B2TYA9 0.000442 45 28 3 144 3 mdtA Multidrug resistance protein MdtA Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
B5YUD2 0.000442 45 28 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O157:H7 (strain EC4115 / EHEC)
Q8X7J5 0.000442 45 28 3 144 3 mdtA Multidrug resistance protein MdtA Escherichia coli O157:H7
Q9I191 0.000486 45 22 8 323 1 pvdR Pyoverdine export membrane fusion protein PvdR Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
C5BHN6 0.000504 45 24 12 342 3 mdtA Multidrug resistance protein MdtA Edwardsiella ictaluri (strain 93-146)
C9XVZ5 0.00085 44 22 7 337 3 mdtA Multidrug resistance protein MdtA Cronobacter turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827 / z3032)

  • Number of RefSeq hits:

General

Source Morganella morganii S2
Locus tag EHELCC_03070
Feature type CDS
Gene acrA
Product Multidrug efflux pump subunit AcrA (membrane-fusion protein)
Location 604223 - 605311 (strand: 1)
Length 1089 (nucleotides) / 362 (amino acids)

Contig

Accession ZDB_213
Length 680219 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_2554
Orthogroup size 6
N. genomes 6

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Genomic region

Domains

PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0845 Cell wall/membrane/envelope biogenesis (M)
Defense mechanisms (V)		 MV Multidrug efflux pump subunit AcrA (membrane-fusion protein)

Protein Sequence

MKNRILIVTTLFLFSVSPAGLADDVRVSVTHPQIIRSAPVITLPGKFVARNEIAIGSPLQQQTVTAVFAEEGQPVEKNQLLATLESPLQSAAVRQLQAETEKAAAYIRQQSVLAAQSQRDLTRMTKLARSGVISTSEFEKAKSDTQAQRALVDAGQAELRQLQAQLAREKSQEDKSKIYAPAAGIISERHAVQGMLSDNTLLFKLIENGEIEFEATAGADELAQMQETSAVTMKTANNRQLNGTVRFISPVLSSLTQSGRVRVTVTDGADLRQGQTGVLTYTAAPREYQSLPYSAVRTGAKGERTVFIVKNNKVMQQPVQTGAIDNGQITVLSPLPPDADVVVNAQAFLTDNDTVTPVKAAQ

Flanking regions ( +/- flanking 50bp)

TATTTAGTTTATTTTAGCGGGCAATGCTTCCGGACGGAAATTGTACCACGATGAAAAACCGTATTTTGATAGTAACCACACTCTTTTTATTTTCTGTATCACCTGCCGGCCTGGCAGATGATGTGCGGGTCAGTGTGACGCATCCGCAAATAATCCGCTCTGCACCGGTCATTACCTTGCCGGGAAAATTTGTGGCCAGAAATGAAATTGCTATCGGCTCGCCGCTGCAGCAACAGACGGTGACGGCAGTATTTGCTGAGGAAGGTCAGCCGGTGGAGAAAAATCAGTTGCTGGCAACCCTGGAATCCCCTTTGCAAAGTGCCGCTGTCCGGCAGTTGCAGGCAGAAACGGAAAAAGCAGCCGCGTATATCCGGCAGCAAAGTGTGCTGGCGGCGCAATCTCAGCGTGATCTGACCCGGATGACAAAACTCGCCCGCAGCGGCGTTATTTCCACCAGTGAATTTGAAAAAGCCAAATCAGACACCCAGGCCCAGCGGGCACTGGTTGATGCCGGGCAGGCAGAACTGCGTCAGTTACAGGCGCAACTGGCACGGGAAAAAAGCCAGGAGGATAAATCAAAAATCTATGCTCCGGCCGCCGGGATTATCAGTGAGCGCCACGCGGTACAGGGCATGCTGTCTGATAACACCCTGCTGTTTAAGCTGATCGAAAACGGTGAGATCGAATTTGAGGCTACTGCGGGGGCTGATGAACTGGCGCAAATGCAGGAAACGTCGGCAGTCACGATGAAAACGGCCAACAACCGGCAACTGAACGGCACTGTCCGGTTTATTTCACCGGTACTTTCCTCTCTGACACAGTCCGGCCGTGTACGGGTCACTGTTACGGACGGCGCTGATTTACGGCAGGGACAGACCGGCGTACTGACATACACGGCCGCGCCCCGTGAGTATCAAAGCCTGCCTTACAGTGCGGTACGCACCGGTGCGAAAGGTGAACGCACAGTGTTTATCGTGAAAAATAACAAAGTGATGCAGCAGCCGGTGCAGACCGGCGCTATTGATAACGGGCAGATTACTGTCCTCAGCCCGCTTCCGCCGGATGCGGATGTGGTGGTCAATGCGCAGGCATTTTTAACTGATAATGACACCGTCACACCGGTGAAGGCCGCACAATGAAATTACAGCTTTCCTCATGGGCTATCACCCGTCCGGTTCCGGTCATTGTT