PF00186


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Pfam domain PF00186
Protein list: lists the 17 occurences of the Pfam domain within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Pfam domain of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Pfam domain has been clustered.
Orthogroups are shown in red if they are annotated with that particular Pfam domain in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Pfam domain prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Pfam domain.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Pfam domain prediction.

Description

External link PF00186
Description Dihydrofolate reductase

Occurence in the database

PF00186 is associated with 17 different proteins
The 17 proteins are classified into 3 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_258 FBDBKF_06280 88639 89133 -1 folA type 3 dihydrofolate reductase Morganella morganii S1
1 group_3668 FBDBKF_20545 1833 2330 -1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S1
2 group_3640 FBDBKF_20645 216 689 -1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S1
3 group_258 EHELCC_09325 89211 89705 -1 folA type 3 dihydrofolate reductase Morganella morganii S2
4 group_3640 EHELCC_19890 671 1144 -1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S2
5 group_258 NLDBIP_09705 89211 89705 -1 folA type 3 dihydrofolate reductase Morganella morganii S4
6 group_3668 NLDBIP_19860 155 652 1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S4
7 group_3640 NLDBIP_19925 145 618 1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S4
8 group_258 LHKJJB_08050 127533 128027 1 folA type 3 dihydrofolate reductase Morganella morganii S3
9 group_3668 LHKJJB_19825 387 884 1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S3
10 group_3640 LHKJJB_19885 216 689 -1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S3
11 group_258 HKOGLL_07600 127533 128027 1 folA type 3 dihydrofolate reductase Morganella morganii S5
12 group_3668 HKOGLL_19695 1833 2330 -1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S5
13 group_3640 HKOGLL_19725 216 689 -1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S5
14 group_258 F4V73_RS15640 124958 125452 1 folA type 3 dihydrofolate reductase Morganella psychrotolerans
15 group_258 F4V73_RS17885 19299 19784 -1 dihydrofolate reductase Morganella psychrotolerans
16 group_258 PMI_RS11560 2549655 2550140 -1 folA type 3 dihydrofolate reductase Proteus mirabilis HI4320