Orthogroup:group_3671


Homologs in group_3671

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4 homologs were identified in 4 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Source Gene Product
FBDBKF_20545 FBDBKF_20545 Morganella morganii S1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12
NLDBIP_19860 NLDBIP_19860 Morganella morganii S4 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12
LHKJJB_19825 LHKJJB_19825 Morganella morganii S3 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12
HKOGLL_19695 HKOGLL_19695 Morganella morganii S5 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12

Distribution of group_3671 homologs

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Number of homologs in each genome (first column and blue bar chart)

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Phylogeny of group_3671 (midpoint rooted)


Phylogeny of the RefSeq best hits of group_3671

Orthogroup content: 4 members

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This page summarizes the annotation of all members of the orthologous group group_3671.
Gene name(s), gene product(s), a summary of protein lenght, and annotations (when available) are provided. Additionally, the number of times (occurence) an annotation is observed in the orthogroup is reported for each annotation.

Orthologs were identified with OrthoFinder. The annotation of orthologous proteins can differ depending the approach used to annotate the source genomes. Automated annotations are also subject to errors. Spurious clustering of non-orthologous proteins can also happen. This page allows to check for eventual inconsistencies.

Gene

# Gene name Occurence
1 dfrA12 4

Product

# Product Occurence
1 trimethoprim-resistant dihydrofolate reductase DfrA12 4

COG entry Annotation(s)

ID Occurences Function(s) cat. Function(s) descr. Description
COG0262 4 H Coenzyme transport and metabolism (H) Dihydrofolate reductase

Kegg Ortholog Annotation(s)

KO Occurences Description Pathways Modules
K18590 4 dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] One carbon pool by folate
Folate biosynthesis
Metabolic pathways		 -

Pfam domain Annotation(s)

Domain ID Occurences Description
PF00186 4 Dihydrofolate reductase

AMR gene Annotation(s)

Gene Occurences Description Scope Type Class Subclass HMM
dfrA12 4 trimethoprim-resistant dihydrofolate reductase DfrA12 core AMR TRIMETHOPRIM TRIMETHOPRIM NF000053 

Annotations of the 90 SwissProt hits

Annotation Number of occurrences
Bifunctional dihydrofolate reductase-thymidylate synthase 10
Bifunctional dihydrofolate reductase-thymidylate synthase 1 1
Bifunctional dihydrofolate reductase-thymidylate synthase 2 1
Dihydrofolate reductase 55
Dihydrofolate reductase 1 1
Dihydrofolate reductase 2 1
Dihydrofolate reductase 2, mitochondrial 1
Dihydrofolate reductase HdrA 1
Dihydrofolate reductase HdrB 1
Dihydrofolate reductase type 1 1
Dihydrofolate reductase type 1 from Tn4003 1
Dihydrofolate reductase type 15 1
Dihydrofolate reductase type 3 1
Dihydrofolate reductase type 5 1
Dihydrofolate reductase type 6 1
Dihydrofolate reductase type 7 1
Dihydrofolate reductase type 8 2
Dihydrofolate reductase type 9 1
Dihydrofolate reductase type A10 1
Dihydrofolate reductase type A13 1
Putative bifunctional dihydrofolate reductase-thymidylate synthase 1
Putative dihydrofolate reductase 1
Segregation and condensation protein A 2
Viral dihydrofolate reductase 2

Protein length

Unique protein length 165

Protein length distribution