blaNDM-1


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected AMR genes blaNDM-1, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the AMR genes within the database. 4 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the AMR gene(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported AMR genes has been clustered.
In red the AMR genes with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and AMR genes prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered AMR genes.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or AMR genes prediction.

Description

Gene blaNDM-1
Description subclass B1 metallo-beta-lactamase NDM-1
Scope core
Type AMR
Class BETA-LACTAM
Subclass CARBAPENEM
HMM NF000259 

Occurence in the database

blaNDM-1 is associated with 4 different proteins (see tab "Protein list" and "Profile")
The 4 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_3667 FBDBKF_20150 2244 3056 -1 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1 Morganella morganii S1
1 group_3667 NLDBIP_19595 4559 5371 1 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1 Morganella morganii S4
2 group_3667 LHKJJB_19560 4559 5371 1 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1 Morganella morganii S3
3 group_3667 HKOGLL_19475 4559 5371 1 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1 Morganella morganii S5