Homologs in group_2223

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_16990 FBDBKF_16990 82.1 Morganella morganii S1 nhaP Na+/H+ antiporter
EHELCC_16600 EHELCC_16600 82.1 Morganella morganii S2 nhaP Na+/H+ antiporter
NLDBIP_16810 NLDBIP_16810 82.1 Morganella morganii S4 nhaP Na+/H+ antiporter
LHKJJB_16660 LHKJJB_16660 82.1 Morganella morganii S3 nhaP Na+/H+ antiporter
HKOGLL_17625 HKOGLL_17625 82.1 Morganella morganii S5 nhaP Na+/H+ antiporter
F4V73_RS18450 F4V73_RS18450 82.7 Morganella psychrotolerans - Na+/H+ antiporter

Distribution of the homologs in the orthogroup group_2223

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2223

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P32703 0.0 770 69 0 549 3 yjcE Uncharacterized Na(+)/H(+) exchanger YjcE Escherichia coli (strain K12)
A7Z8R4 3.46e-101 322 38 13 556 3 nhaK Sodium, potassium, lithium and rubidium/H(+) antiporter Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)
O32212 8.04e-97 311 36 12 554 1 nhaK Sodium, potassium, lithium and rubidium/H(+) antiporter Bacillus subtilis (strain 168)
A8FHE3 4.13e-96 309 39 11 545 3 nhaK Sodium, potassium, lithium and rubidium/H(+) antiporter Bacillus pumilus (strain SAFR-032)
P65527 1.56e-34 140 29 12 511 3 BQ2027_MB2309 Uncharacterized Na(+)/H(+) exchanger Mb2309 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P9WJI3 1.56e-34 140 29 12 511 1 Rv2287 Uncharacterized Na(+)/H(+) exchanger Rv2287 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WJI2 1.56e-34 140 29 12 511 3 MT2345 Uncharacterized Na(+)/H(+) exchanger MT2345 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Q93HU4 1.4e-29 125 24 10 457 1 apnhaP Na(+)/H(+) antiporter ApNhaP Aphanothece halophytica
Q9LCB5 1.34e-28 122 26 20 547 1 nhaG Na(+)/H(+) antiporter NhaG Bacillus atrophaeus
Q2XWL3 4.67e-27 116 26 6 365 1 nhaH Na(+)/H(+) antiporter NhaH Halobacillus dabanensis
B0LJC9 2.23e-24 108 25 7 367 1 nhaH Na(+)/H(+) antiporter NhaH Halobacillus aidingensis
P73863 2.18e-22 104 26 17 516 1 nhaS1 Low-affinity Na(+)/H(+) antiporter NhaS1 Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q3ZAS0 1.34e-18 93 24 13 432 1 Slc9a2 Sodium/hydrogen exchanger 2 Mus musculus
Q6AI14 1.6e-18 93 24 15 457 1 SLC9A4 Sodium/hydrogen exchanger 4 Homo sapiens
Q9UBY0 1.89e-18 92 24 14 458 1 SLC9A2 Sodium/hydrogen exchanger 2 Homo sapiens
P48763 1.99e-18 92 22 19 614 1 Slc9a2 Sodium/hydrogen exchanger 2 Rattus norvegicus
P50482 2.41e-18 92 24 13 432 2 SLC9A2 Sodium/hydrogen exchanger 2 Oryctolagus cuniculus
Q8BUE1 7.79e-18 90 23 15 463 1 Slc9a4 Sodium/hydrogen exchanger 4 Mus musculus
P26434 2.47e-17 89 23 14 458 1 Slc9a4 Sodium/hydrogen exchanger 4 Rattus norvegicus
Q4L208 1.2e-16 86 22 14 524 1 Slc9a8 Sodium/hydrogen exchanger 8 Rattus norvegicus
Q9Y2E8 1.47e-16 86 22 14 524 1 SLC9A8 Sodium/hydrogen exchanger 8 Homo sapiens
Q8R4D1 2.25e-16 85 22 14 524 1 Slc9a8 Sodium/hydrogen exchanger 8 Mus musculus
Q552S0 3.14e-16 85 25 6 252 2 nhe1 Sodium/hydrogen exchanger 1 Dictyostelium discoideum
Q8T5S1 3.39e-16 85 22 17 483 2 nhx-2 Na(+)/H(+) exchanger protein 2 Caenorhabditis elegans
Q5ZJ75 5.99e-15 81 22 16 528 2 None Sodium/hydrogen exchanger 8 Gallus gallus
Q8S397 2.21e-14 79 26 8 250 2 NHX4 Sodium/hydrogen exchanger 4 Arabidopsis thaliana
Q8BLV3 2.98e-14 79 25 7 266 1 Slc9a7 Sodium/hydrogen exchanger 7 Mus musculus
A3RL54 3.45e-14 79 23 17 434 1 SLC9C1 Sperm-specific sodium:proton exchanger Strongylocentrotus purpuratus
Q96T83 6.1e-14 78 25 8 265 1 SLC9A7 Sodium/hydrogen exchanger 7 Homo sapiens
F7B113 9.13e-14 77 22 13 351 1 SLC9A9 Sodium/hydrogen exchanger 9 Equus caballus
D4A7H1 1.56e-13 77 22 12 356 1 Slc9a9 Sodium/hydrogen exchanger 9 Rattus norvegicus
Q8BZ00 1.99e-13 76 22 12 356 1 Slc9a9 Sodium/hydrogen exchanger 9 Mus musculus
O13726 2.98e-13 75 22 5 261 1 SPAC15A10.06 Uncharacterized Na(+)/H(+) antiporter C15A10.06 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q8IVB4 6.04e-13 75 22 12 350 1 SLC9A9 Sodium/hydrogen exchanger 9 Homo sapiens
P35449 7.45e-13 75 22 13 445 2 nhx-9 Probable Na(+)/H(+) antiporter nhx-9 Caenorhabditis elegans
Q04121 8.21e-13 74 26 7 256 1 NHX1 Endosomal/prevacuolar sodium/hydrogen exchanger Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D3ZJ86 1.74e-11 70 24 6 262 1 Slc9a6 Sodium/hydrogen exchanger 6 Rattus norvegicus
A1L3P4 3.81e-11 69 22 5 269 1 Slc9a6 Sodium/hydrogen exchanger 6 Mus musculus
Q92581 4.49e-11 69 22 5 269 1 SLC9A6 Sodium/hydrogen exchanger 6 Homo sapiens
Q9LKW9 4.57e-11 69 22 20 494 1 NHX7 Sodium/hydrogen exchanger 7 Arabidopsis thaliana
P48764 7.74e-11 68 22 14 409 1 SLC9A3 Sodium/hydrogen exchanger 3 Homo sapiens
Q8RWU6 1.13e-10 67 22 11 376 1 NHX6 Sodium/hydrogen exchanger 6 Arabidopsis thaliana
Q56XP4 2.65e-10 66 22 8 253 2 NHX2 Sodium/hydrogen exchanger 2 Arabidopsis thaliana
Q3YL57 3.99e-10 66 22 22 556 2 NHX8 Sodium/hydrogen exchanger 8 Arabidopsis thaliana
Q01345 5.23e-10 65 22 8 336 2 None Na(+)/H(+) exchanger beta Oncorhynchus mykiss
P26433 9.58e-10 65 23 11 344 1 Slc9a3 Sodium/hydrogen exchanger 3 Rattus norvegicus
Q9SXJ8 1.5e-09 64 22 8 262 2 NHX1 Sodium/hydrogen exchanger 1 Oryza sativa subsp. japonica
Q84WG1 2.79e-09 63 21 17 435 1 NHX3 Sodium/hydrogen exchanger 3 Arabidopsis thaliana
P26432 3.33e-09 63 24 8 266 1 SLC9A3 Sodium/hydrogen exchanger 3 Oryctolagus cuniculus
G3X939 3.62e-09 63 23 11 344 1 Slc9a3 Sodium/hydrogen exchanger 3 Mus musculus
P74393 5.46e-09 62 23 15 531 1 nhaS2 Na(+)/H(+) antiporter NhaS2 Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
G3XD29 5.98e-09 62 24 7 384 1 nhaP Na(+)/H(+) antiporter NhaP Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q4R8V4 8.93e-09 61 20 15 524 2 SLC9A8 Sodium/hydrogen exchanger 8 Macaca fascicularis
Q28362 1.19e-08 61 23 12 344 1 SLC9A3 Sodium/hydrogen exchanger 3 Didelphis virginiana
Q68KI4 1.23e-08 61 22 8 253 1 NHX1 Sodium/hydrogen exchanger 1 Arabidopsis thaliana
O16452 2.01e-08 60 24 10 355 2 nhx-3 Probable Na(+)/H(+) antiporter nhx-3 Caenorhabditis elegans
Q8S396 2.01e-07 57 23 13 370 2 NHX5 Sodium/hydrogen exchanger 5 Arabidopsis thaliana
G5EBK1 2.86e-07 57 24 8 308 1 pbo-4 Na(+)/H(+) exchanger protein 7 Caenorhabditis elegans
B2RXE2 6.03e-07 56 24 8 257 1 Slc9a5 Sodium/hydrogen exchanger 5 Mus musculus
Q14940 6.97e-07 55 23 12 343 1 SLC9A5 Sodium/hydrogen exchanger 5 Homo sapiens
O14123 1.17e-06 55 23 7 249 1 sod22 Probable Na(+)/H(+) antiporter C3A11.09 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q9Z0X2 1.34e-06 55 24 8 257 1 Slc9a5 Sodium/hydrogen exchanger 5 Rattus norvegicus
M5A7P9 1.65e-06 54 23 9 271 1 slc9a3 Sodium/hydrogen exchanger 3 Triakis scyllium
P23791 5.2e-06 53 23 13 394 1 SLC9A1 Sodium/hydrogen exchanger 1 Oryctolagus cuniculus
Q6UJY2 8.34e-06 52 21 19 463 1 Slc9c1 Solute carrier family 9 member C1 Mus musculus
Q28036 1.29e-05 52 23 13 414 2 SLC9A1 Sodium/hydrogen exchanger 1 Bos taurus
P48762 1.49e-05 51 23 13 394 2 SLC9A1 Sodium/hydrogen exchanger 1 Sus scrofa
Q61165 1.65e-05 51 23 13 394 1 Slc9a1 Sodium/hydrogen exchanger 1 Mus musculus
P19634 1.97e-05 51 23 13 394 1 SLC9A1 Sodium/hydrogen exchanger 1 Homo sapiens
P26431 3.49e-05 50 22 13 394 1 Slc9a1 Sodium/hydrogen exchanger 1 Rattus norvegicus

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS17525
Feature type CDS
Gene -
Product Na+/H+ antiporter
Location 3846850 - 3848499 (strand: 1)
Length 1650 (nucleotides) / 549 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_2223
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00999 Sodium/hydrogen exchanger family

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0025 Inorganic ion transport and metabolism (P) P NhaP-type Na+/H+ or K+/H+ antiporter

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K24163 monovalent cation/hydrogen antiporter - -

Protein Sequence

MEIFFTILILILVVSVSGVITKVIPFRIPLPLIQIVIGALLAWPQFGLHVTFDPELFLVLLIPPLLFVDGWKTPTREFIQNGREIFILVLVLVMVTVVGIGYLIYWIMPSIPLISAFALAAVLSPTDAVALSSIVGKGRIPKRIMGVLEGEALMNDASGLVALKFAVAVAMGTMIFTVGGATFEFFKVAIGGLLAGIAVTLVYSKSLRLMSRWSGDDPATQIVFMLLLPFASYLIAEHIGFSGILAAVAAGMTISKSGVIRNAPLAMRLRADSVWSMLEFVFNGLVFIMLGLQLPVIWTSSVIQADLDPEVEVWMLFAAVFVIYFALLILRFTWLWLMKKISHLFMKKHPLDFATYTTRELWLSSFAGVRGAITLAGALSIPLFLTDGSTFPGRYQIIFIAAGVILLSILVGIISLPFLLKGIKATDKEADKNEVRYAKKVMAEVAIVSLNKMEERLAASTEEQLDAEEINEVASRVAGYLRRRTADQDEMMHNMLVEDLERRFRLTALRAERGELYHLRATRKISNETLQLLLHELDLMEALLVEKDS

Flanking regions ( +/- flanking 50bp)

ATCAGGAAAGATGGCAGATTCTTAGATAAAAATAAGCATGTAAGGGTAGCATGGAAATTTTCTTTACTATTTTAATTTTAATATTGGTAGTTTCTGTTTCAGGTGTCATTACCAAAGTTATTCCTTTTCGCATTCCATTACCATTAATCCAGATTGTGATCGGGGCACTTTTGGCTTGGCCTCAGTTTGGTTTACATGTCACCTTTGATCCTGAACTCTTCTTAGTTTTACTGATCCCTCCTTTACTTTTTGTTGATGGATGGAAAACCCCCACACGTGAATTTATCCAAAATGGTCGAGAGATCTTTATCCTTGTGCTGGTTTTGGTGATGGTGACAGTAGTAGGTATTGGTTACCTTATTTACTGGATAATGCCTAGTATTCCACTTATTTCTGCTTTCGCGCTCGCCGCGGTTCTCTCGCCAACTGATGCGGTGGCATTATCCTCGATTGTCGGTAAGGGGCGAATACCGAAGCGGATCATGGGGGTTTTAGAAGGCGAAGCCTTAATGAATGATGCTTCGGGTCTGGTGGCGCTGAAATTTGCCGTTGCTGTGGCTATGGGCACGATGATATTTACCGTGGGTGGCGCAACCTTTGAGTTTTTTAAAGTGGCAATAGGCGGTTTATTAGCGGGTATTGCGGTAACGTTAGTCTATAGTAAATCTCTGCGATTGATGAGCCGTTGGAGTGGTGATGATCCTGCCACTCAAATTGTCTTTATGTTGCTGTTGCCTTTTGCTTCTTATTTGATTGCTGAACATATTGGCTTTTCCGGGATCCTTGCTGCCGTGGCCGCAGGTATGACTATCAGTAAATCAGGTGTGATCCGCAATGCACCATTGGCGATGCGCTTGCGTGCAGATAGTGTCTGGTCAATGTTAGAGTTTGTCTTTAACGGACTGGTCTTTATTATGCTGGGTTTACAGCTTCCTGTTATTTGGACAAGCTCGGTTATTCAAGCTGATCTCGATCCTGAAGTTGAAGTATGGATGCTGTTTGCCGCCGTCTTTGTTATCTATTTTGCGTTACTGATTTTACGTTTTACATGGTTATGGCTAATGAAGAAAATCAGCCATCTCTTTATGAAAAAACATCCCCTTGATTTCGCCACTTATACGACGAGAGAATTATGGCTATCTTCTTTTGCCGGGGTACGTGGTGCTATCACCTTAGCCGGTGCGCTCTCTATACCGCTATTTTTAACTGATGGCAGTACTTTCCCTGGGCGCTATCAGATAATCTTTATTGCGGCAGGGGTGATCCTGTTATCCATTTTGGTCGGTATTATTTCATTACCTTTCTTACTAAAAGGGATTAAAGCTACCGATAAAGAAGCGGATAAAAATGAAGTACGTTATGCCAAGAAAGTCATGGCAGAAGTCGCTATTGTTAGCCTCAATAAAATGGAAGAGCGTTTAGCTGCAAGTACAGAAGAGCAACTAGATGCGGAAGAAATTAATGAAGTAGCTTCTCGAGTTGCCGGCTATTTAAGACGACGTACCGCGGATCAGGACGAGATGATGCACAATATGTTGGTGGAAGATCTGGAAAGACGTTTTCGCCTAACGGCATTGCGTGCAGAGCGTGGTGAGCTTTATCACTTACGTGCAACGCGTAAAATTAGTAACGAAACACTACAACTTTTGCTTCATGAATTAGATTTAATGGAAGCGCTGTTAGTTGAGAAAGACAGTTAATTATGTGGCTACTGGTTATTACAACGTTGTTATGGGCGGCTTCTTTTAGT