Homologs in group_2223

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_16990 FBDBKF_16990 100.0 Morganella morganii S1 nhaP Na+/H+ antiporter
NLDBIP_16810 NLDBIP_16810 100.0 Morganella morganii S4 nhaP Na+/H+ antiporter
LHKJJB_16660 LHKJJB_16660 100.0 Morganella morganii S3 nhaP Na+/H+ antiporter
HKOGLL_17625 HKOGLL_17625 100.0 Morganella morganii S5 nhaP Na+/H+ antiporter
F4V73_RS18450 F4V73_RS18450 96.5 Morganella psychrotolerans - Na+/H+ antiporter
PMI_RS17525 PMI_RS17525 82.1 Proteus mirabilis HI4320 - Na+/H+ antiporter

Distribution of the homologs in the orthogroup group_2223

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2223

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P32703 0.0 780 70 0 548 3 yjcE Uncharacterized Na(+)/H(+) exchanger YjcE Escherichia coli (strain K12)
O32212 6.23e-96 309 36 13 552 1 nhaK Sodium, potassium, lithium and rubidium/H(+) antiporter Bacillus subtilis (strain 168)
A7Z8R4 1.37e-95 308 36 12 549 3 nhaK Sodium, potassium, lithium and rubidium/H(+) antiporter Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)
A8FHE3 1.49e-95 308 37 13 553 3 nhaK Sodium, potassium, lithium and rubidium/H(+) antiporter Bacillus pumilus (strain SAFR-032)
P65527 4.71e-34 139 28 12 509 3 BQ2027_MB2309 Uncharacterized Na(+)/H(+) exchanger Mb2309 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P9WJI3 4.71e-34 139 28 12 509 1 Rv2287 Uncharacterized Na(+)/H(+) exchanger Rv2287 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WJI2 4.71e-34 139 28 12 509 3 MT2345 Uncharacterized Na(+)/H(+) exchanger MT2345 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Q9LCB5 6.35e-28 120 25 22 546 1 nhaG Na(+)/H(+) antiporter NhaG Bacillus atrophaeus
Q93HU4 7.11e-27 117 25 11 399 1 apnhaP Na(+)/H(+) antiporter ApNhaP Aphanothece halophytica
Q2XWL3 8.45e-25 110 27 8 366 1 nhaH Na(+)/H(+) antiporter NhaH Halobacillus dabanensis
B0LJC9 2.48e-21 99 26 8 353 1 nhaH Na(+)/H(+) antiporter NhaH Halobacillus aidingensis
P73863 5.03e-21 100 26 17 514 1 nhaS1 Low-affinity Na(+)/H(+) antiporter NhaS1 Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q3ZAS0 7.85e-20 97 26 15 467 1 Slc9a2 Sodium/hydrogen exchanger 2 Mus musculus
P48763 9.52e-20 97 26 15 467 1 Slc9a2 Sodium/hydrogen exchanger 2 Rattus norvegicus
Q9UBY0 2.34e-19 95 26 15 464 1 SLC9A2 Sodium/hydrogen exchanger 2 Homo sapiens
Q8BUE1 4.35e-19 94 24 15 457 1 Slc9a4 Sodium/hydrogen exchanger 4 Mus musculus
P26434 4.72e-19 94 25 16 457 1 Slc9a4 Sodium/hydrogen exchanger 4 Rattus norvegicus
P50482 4.98e-19 94 26 15 466 2 SLC9A2 Sodium/hydrogen exchanger 2 Oryctolagus cuniculus
Q6AI14 4.98e-18 91 23 12 455 1 SLC9A4 Sodium/hydrogen exchanger 4 Homo sapiens
Q552S0 3.61e-17 88 24 16 398 2 nhe1 Sodium/hydrogen exchanger 1 Dictyostelium discoideum
F7B113 1.43e-15 83 23 10 348 1 SLC9A9 Sodium/hydrogen exchanger 9 Equus caballus
A3RL54 1.8e-15 83 24 14 428 1 SLC9C1 Sperm-specific sodium:proton exchanger Strongylocentrotus purpuratus
D4A7H1 1.38e-14 80 23 13 345 1 Slc9a9 Sodium/hydrogen exchanger 9 Rattus norvegicus
Q8IVB4 1.38e-14 80 23 10 348 1 SLC9A9 Sodium/hydrogen exchanger 9 Homo sapiens
Q8BZ00 1.4e-14 80 23 13 345 1 Slc9a9 Sodium/hydrogen exchanger 9 Mus musculus
Q4L208 1.71e-14 80 21 18 545 1 Slc9a8 Sodium/hydrogen exchanger 8 Rattus norvegicus
Q8R4D1 1.73e-14 80 21 18 545 1 Slc9a8 Sodium/hydrogen exchanger 8 Mus musculus
Q8S397 2.11e-14 79 23 14 429 2 NHX4 Sodium/hydrogen exchanger 4 Arabidopsis thaliana
Q04121 2.27e-14 79 24 13 362 1 NHX1 Endosomal/prevacuolar sodium/hydrogen exchanger Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q9Y2E8 6.75e-14 78 22 17 500 1 SLC9A8 Sodium/hydrogen exchanger 8 Homo sapiens
P35449 1.04e-13 77 23 15 452 2 nhx-9 Probable Na(+)/H(+) antiporter nhx-9 Caenorhabditis elegans
Q8T5S1 1.4e-13 77 22 14 410 2 nhx-2 Na(+)/H(+) exchanger protein 2 Caenorhabditis elegans
Q8BLV3 4.61e-13 75 25 7 265 1 Slc9a7 Sodium/hydrogen exchanger 7 Mus musculus
O13726 1.84e-12 73 23 5 261 1 SPAC15A10.06 Uncharacterized Na(+)/H(+) antiporter C15A10.06 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q96T83 4.66e-12 72 24 11 309 1 SLC9A7 Sodium/hydrogen exchanger 7 Homo sapiens
Q01345 2.94e-11 70 23 8 333 2 None Na(+)/H(+) exchanger beta Oncorhynchus mykiss
A1L3P4 7.31e-11 68 23 4 264 1 Slc9a6 Sodium/hydrogen exchanger 6 Mus musculus
Q92581 7.5e-11 68 23 4 264 1 SLC9A6 Sodium/hydrogen exchanger 6 Homo sapiens
Q5ZJ75 1.02e-10 68 21 17 540 2 None Sodium/hydrogen exchanger 8 Gallus gallus
Q9LKW9 1.3e-10 68 26 11 289 1 NHX7 Sodium/hydrogen exchanger 7 Arabidopsis thaliana
D3ZJ86 1.58e-10 67 23 4 264 1 Slc9a6 Sodium/hydrogen exchanger 6 Rattus norvegicus
Q56XP4 2.22e-10 67 22 11 340 2 NHX2 Sodium/hydrogen exchanger 2 Arabidopsis thaliana
Q8RWU6 2.63e-09 63 20 9 365 1 NHX6 Sodium/hydrogen exchanger 6 Arabidopsis thaliana
P48764 3.36e-09 63 23 20 495 1 SLC9A3 Sodium/hydrogen exchanger 3 Homo sapiens
O16452 6.2e-09 62 23 16 427 2 nhx-3 Probable Na(+)/H(+) antiporter nhx-3 Caenorhabditis elegans
Q9SXJ8 8.1e-09 62 21 9 264 2 NHX1 Sodium/hydrogen exchanger 1 Oryza sativa subsp. japonica
Q68KI4 8.5e-09 61 21 11 342 1 NHX1 Sodium/hydrogen exchanger 1 Arabidopsis thaliana
Q4R8V4 2.08e-08 60 22 7 280 2 SLC9A8 Sodium/hydrogen exchanger 8 Macaca fascicularis
Q84WG1 2.35e-08 60 23 11 268 1 NHX3 Sodium/hydrogen exchanger 3 Arabidopsis thaliana
P26433 3.33e-08 60 22 18 492 1 Slc9a3 Sodium/hydrogen exchanger 3 Rattus norvegicus
G3XD29 3.9e-08 59 23 6 376 1 nhaP Na(+)/H(+) antiporter NhaP Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P26432 6.15e-08 59 23 15 413 1 SLC9A3 Sodium/hydrogen exchanger 3 Oryctolagus cuniculus
G3X939 1.2e-07 58 22 18 492 1 Slc9a3 Sodium/hydrogen exchanger 3 Mus musculus
Q14940 1.55e-07 58 24 15 361 1 SLC9A5 Sodium/hydrogen exchanger 5 Homo sapiens
Q3YL57 1.6e-07 58 26 10 286 2 NHX8 Sodium/hydrogen exchanger 8 Arabidopsis thaliana
P74393 2.31e-07 57 23 17 531 1 nhaS2 Na(+)/H(+) antiporter NhaS2 Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q28362 4.14e-07 56 22 19 508 1 SLC9A3 Sodium/hydrogen exchanger 3 Didelphis virginiana
B2RXE2 4.2e-07 56 23 12 359 1 Slc9a5 Sodium/hydrogen exchanger 5 Mus musculus
Q9Z0X2 1.07e-06 55 25 6 217 1 Slc9a5 Sodium/hydrogen exchanger 5 Rattus norvegicus
Q6UJY2 2.24e-06 54 22 14 358 1 Slc9c1 Solute carrier family 9 member C1 Mus musculus
O14123 3.99e-06 53 23 6 248 1 sod22 Probable Na(+)/H(+) antiporter C3A11.09 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q8S396 1.23e-05 51 21 12 346 2 NHX5 Sodium/hydrogen exchanger 5 Arabidopsis thaliana
G5EBK1 1.26e-05 52 23 8 271 1 pbo-4 Na(+)/H(+) exchanger protein 7 Caenorhabditis elegans
M5A7P9 3.03e-05 50 21 12 351 1 slc9a3 Sodium/hydrogen exchanger 3 Triakis scyllium
P23791 8.16e-05 49 24 10 394 1 SLC9A1 Sodium/hydrogen exchanger 1 Oryctolagus cuniculus
Q28036 0.000156 48 24 10 394 2 SLC9A1 Sodium/hydrogen exchanger 1 Bos taurus
P48762 0.000194 48 24 10 395 2 SLC9A1 Sodium/hydrogen exchanger 1 Sus scrofa
Q61165 0.000277 47 24 10 394 1 Slc9a1 Sodium/hydrogen exchanger 1 Mus musculus
P26431 0.00032 47 23 10 394 1 Slc9a1 Sodium/hydrogen exchanger 1 Rattus norvegicus
P19634 0.000483 47 24 10 394 1 SLC9A1 Sodium/hydrogen exchanger 1 Homo sapiens

  • Number of RefSeq hits:

General

Source Morganella morganii S2
Locus tag EHELCC_16600
Feature type CDS
Gene nhaP
Product Na+/H+ antiporter
Location 40214 - 41863 (strand: 1)
Length 1650 (nucleotides) / 549 (amino acids)

Contig

Accession ZDB_229
Length 57314 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_2223
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00999 Sodium/hydrogen exchanger family

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0025 Inorganic ion transport and metabolism (P) P NhaP-type Na+/H+ or K+/H+ antiporter

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K24163 monovalent cation/hydrogen antiporter - -

Protein Sequence

MEIFFTILILILVVSVSGVLTKMIPYRIPLPIIQIAMGALLAFPQFGLHVTFDPELFLVLLIPPLLFVDGWKTPTREFMQKGREIFILVLFLVLVTVIGIGYLIYWLMPGIELIPAFALAAVLSPTDAVALSSIVGKGRIPKQMMGILEGEALMNDASGLVALKFAVAIVMGTMIFSVTGVTLEFFKVAIGGLLAGVAVTWLYSKSLRLMSRWSGDDPATQIVFMLLLPFASYLIAEHIGVSGILAAVAAGMTISKSGVIRNAPLAMRLRADNVWGMLEFVFNGLVFIMLGLQLPGIWQVSVIEAELDPTVETWMLFTAVIVIYFALLVLRFCWLWMMKTVSRLTLKRKPLDFTFYTTRELWLASFAGVRGAITLAGVLSIPLFLPDGTPFPARYQMVFIAAGVIIFSLFMGVVSLPFLLKGMHVGDKQADANEIRAAKAAMAEVAIVSIGKMEERLSASSDEALDAEAISEVASRVAGHLRRRTAGDDEMEYNLQVEDLERRFRLTALRAERGELYHQRATRNISNETLQLLLHDLDLLEALLVEKET

Flanking regions ( +/- flanking 50bp)

GTATCTTTTTGTCAGCGGGCTGATGAAGCCCTAAGTTCAGTAAGGGTAATATGGAAATATTCTTTACGATTCTTATTTTGATTCTGGTCGTGTCGGTGTCCGGTGTTCTCACCAAAATGATCCCGTATCGTATTCCGTTACCCATCATTCAGATCGCGATGGGGGCTCTGCTTGCCTTCCCGCAGTTTGGTCTGCATGTCACGTTCGACCCTGAACTGTTTCTCGTCCTGCTGATACCGCCGTTGCTGTTTGTTGACGGCTGGAAAACCCCGACCCGGGAATTTATGCAGAAAGGGCGGGAAATTTTCATCCTGGTGCTGTTCCTGGTGCTGGTCACTGTTATCGGTATCGGGTATCTGATCTACTGGCTGATGCCGGGGATTGAGCTGATCCCGGCCTTTGCCCTTGCGGCGGTGTTGTCTCCGACAGATGCCGTGGCGTTGTCGTCGATTGTCGGCAAAGGGCGCATTCCGAAACAGATGATGGGCATTCTGGAAGGGGAGGCGCTGATGAATGACGCCTCCGGCCTGGTCGCGCTGAAATTTGCCGTGGCGATTGTCATGGGCACGATGATTTTCTCCGTCACCGGTGTCACGCTGGAATTCTTCAAAGTCGCAATCGGCGGCCTGCTGGCGGGGGTGGCAGTTACCTGGCTGTACAGTAAGTCGCTGCGCCTGATGAGCCGCTGGAGCGGGGATGACCCGGCCACGCAAATCGTCTTTATGTTACTGCTGCCGTTCGCCTCTTATCTGATTGCGGAACACATCGGTGTGTCCGGTATCCTGGCGGCCGTGGCGGCGGGGATGACCATCAGTAAATCCGGGGTTATCCGCAATGCGCCGCTGGCGATGCGTCTGCGGGCGGATAATGTCTGGGGAATGCTGGAATTCGTCTTTAACGGTCTGGTCTTTATTATGCTCGGCCTGCAGTTGCCGGGGATTTGGCAGGTGTCGGTGATTGAGGCGGAGCTGGATCCGACCGTCGAAACCTGGATGCTGTTTACCGCGGTTATCGTTATCTATTTTGCCCTGCTGGTGCTGCGTTTCTGCTGGCTGTGGATGATGAAAACCGTCAGCCGCCTGACCTTAAAACGCAAGCCGCTGGATTTCACCTTCTACACCACCCGTGAATTGTGGCTGGCATCATTTGCCGGGGTGCGCGGGGCGATAACTCTGGCGGGTGTGCTCTCTATCCCGCTGTTCCTGCCGGACGGCACACCGTTCCCGGCGCGTTATCAGATGGTGTTTATCGCCGCCGGGGTGATTATCTTCTCGCTCTTTATGGGAGTGGTATCGCTGCCGTTCCTGCTCAAAGGGATGCATGTCGGGGATAAACAGGCGGATGCCAATGAAATCCGTGCGGCGAAAGCGGCGATGGCGGAAGTGGCAATTGTCAGTATCGGCAAGATGGAAGAGCGTCTGTCCGCCAGTTCAGATGAGGCACTGGATGCGGAAGCTATCAGTGAAGTGGCCTCCAGGGTGGCCGGGCATCTCAGGCGGCGTACTGCCGGTGATGATGAGATGGAATATAATCTCCAGGTGGAAGATCTGGAACGCCGTTTCCGTCTGACTGCACTGCGTGCCGAGCGCGGGGAGCTGTATCACCAGCGTGCGACCCGTAATATCAGCAATGAAACCCTGCAACTGCTGCTGCATGACCTGGATCTGCTGGAAGCCCTGCTGGTTGAGAAAGAAACATAACCGATGCCGTTACTGATTATTACCACAATTCTGTGGGCCGCATCGTTCAG