Homologs in group_1423

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_08465 FBDBKF_08465 67.6 Morganella morganii S1 hflK FtsH protease activity modulator HflK
EHELCC_13060 EHELCC_13060 67.6 Morganella morganii S2 hflK FtsH protease activity modulator HflK
NLDBIP_13400 NLDBIP_13400 67.6 Morganella morganii S4 hflK FtsH protease activity modulator HflK
LHKJJB_13155 LHKJJB_13155 67.6 Morganella morganii S3 hflK FtsH protease activity modulator HflK
HKOGLL_11875 HKOGLL_11875 67.6 Morganella morganii S5 hflK FtsH protease activity modulator HflK
F4V73_RS09685 F4V73_RS09685 69.2 Morganella psychrotolerans hflK FtsH protease activity modulator HflK

Distribution of the homologs in the orthogroup group_1423

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1423

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0ABC7 7.15e-156 449 67 3 364 1 hflK Modulator of FtsH protease HflK Escherichia coli (strain K12)
P0ABC8 7.15e-156 449 67 3 364 3 hflK Protein HflK Escherichia coli O157:H7
Q8K914 4.4e-128 379 52 5 363 3 hflK Protein HflK Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
P57631 3.1e-124 369 49 3 361 3 hflK Protein HflK Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
P44546 8.26e-124 368 49 6 400 3 hflK Protein HflK Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P40605 8.73e-112 337 48 5 413 3 hflK Protein HflK Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Q9KV09 3.07e-110 332 50 7 406 3 hflK Protein HflK Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q89A39 1.83e-77 249 36 4 354 3 hflK Protein HflK Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
O83151 1.03e-38 145 31 2 280 3 hflK Protein HflK Treponema pallidum (strain Nichols)
O51221 2.41e-32 127 29 3 282 3 hflK Protein HflK Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
O26788 7e-13 72 29 2 198 3 MTH_692 Uncharacterized protein MTH_692 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
P63694 7.2e-12 70 25 5 231 3 BQ2027_MB1524 Uncharacterized protein Mb1524 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P9WPR9 7.2e-12 70 25 5 231 1 Rv1488 Uncharacterized protein Rv1488 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WPR8 7.2e-12 70 25 5 231 3 MT1533.2 Uncharacterized protein MT1533.2 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P0DKS0 2.89e-09 61 25 7 208 3 qmcA Protein QmcA Wigglesworthia glossinidia brevipalpis
P72655 3.58e-08 58 23 4 208 3 slr1128 Uncharacterized protein slr1128 Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
P0AA56 3.17e-07 55 24 7 222 3 qmcA Protein QmcA Shigella flexneri
P0AA53 3.17e-07 55 24 7 222 1 qmcA Protein QmcA Escherichia coli (strain K12)
P0AA54 3.17e-07 55 24 7 222 3 qmcA Protein QmcA Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P0AA55 3.17e-07 55 24 7 222 3 qmcA Protein QmcA Escherichia coli O157:H7
O28852 3.28e-07 54 25 2 172 3 AF_1420 Uncharacterized protein AF_1420 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
Q58237 2.71e-06 51 24 4 193 3 MJ0827 Uncharacterized protein MJ0827 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q9UJZ1 3.73e-06 52 22 3 209 1 STOML2 Stomatin-like protein 2, mitochondrial Homo sapiens
Q99JB2 6.83e-06 51 22 3 209 1 Stoml2 Stomatin-like protein 2, mitochondrial Mus musculus
Q20657 7.32e-06 50 25 5 191 3 sto-3 Stomatin-3 Caenorhabditis elegans
Q4FZT0 7.54e-06 51 22 3 209 1 Stoml2 Stomatin-like protein 2, mitochondrial Rattus norvegicus
Q8K915 1.19e-05 50 22 8 262 3 hflC Protein HflC Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Q32LL2 1.2e-05 50 22 3 209 2 STOML2 Stomatin-like protein 2, mitochondrial Bos taurus
H2FLJ1 1.22e-05 50 24 7 229 2 stl-1 Stomatin-like protein stl-1 Caenorhabditis elegans
P57630 1.43e-05 50 22 6 244 3 hflC Protein HflC Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Q9SRH6 1.54e-05 50 24 6 189 1 HIR3 Hypersensitive-induced response protein 3 Arabidopsis thaliana
Q5UP73 2.03e-05 49 22 6 211 3 MIMI_R614 Putative band 7 family protein R614 Acanthamoeba polyphaga mimivirus
O60121 4.93e-05 48 23 3 202 3 SPBC16G5.07c Uncharacterized protein C16G5.07c Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q9FHM7 0.000107 47 25 6 190 1 HIR4 Hypersensitive-induced response protein 4 Arabidopsis thaliana
Q9UBI4 0.000356 46 22 7 227 1 STOML1 Stomatin-like protein 1 Homo sapiens
P44545 0.000359 45 23 10 264 3 hflC Protein HflC Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q9KV08 0.000491 45 24 11 287 3 hflC Protein HflC Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
P0ABC6 0.000579 45 22 2 135 3 hflC Modulator of FtsH protease HflC Shigella flexneri
P0ABC3 0.000579 45 22 2 135 1 hflC Modulator of FtsH protease HflC Escherichia coli (strain K12)
P0ABC4 0.000579 45 22 2 135 3 hflC Modulator of FtsH protease HflC Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P0ABC5 0.000579 45 22 2 135 3 hflC Modulator of FtsH protease HflC Escherichia coli O157:H7

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS16760
Feature type CDS
Gene hflK
Product FtsH protease activity modulator HflK
Location 3694376 - 3695650 (strand: 1)
Length 1275 (nucleotides) / 424 (amino acids)
In genomic island -

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_1423
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF01145 SPFH domain / Band 7 family
PF12221 Bacterial membrane protein N terminal

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0330 Posttranslational modification, protein turnover, chaperones (O) O Regulator of protease activity HflC, stomatin/prohibitin superfamily

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K04088 modulator of FtsH protease HflK - -

Protein Sequence

MAWNQPGNNGQDRDPWGNRNGGNNNGDGNSNGNQGGRDRKASDLDDLFRKLSAKLGGFGGKKGGNSSSGQNGGPRGNAGNVLVSLALGAVVVVWAASGFYTIKEAEQGVVTRFGKFYQIVEPGLNWKPTFIDEVQPVNVKTIRDLTTGGMMLTSDENMVQVEINVQYVVSDPEAFLFNVTTPMNSLGQATDSAVRGVIGRSEMEKILTSNRSEIRDQTRQELEETIRPYKMGISIVDVNFQVARPPEAVKAAFDDVIAAREEEQKTIRQAEAYKNEVLPLAKGNAQRMIEEATAYKTSVVMKAEGEVASFAKILPEYRAAPEITRERLYIETMEKVLSKTRKVIANDKGNSMLVLPLEQMLRQQPKAPTSVNSVTEAPARISTPTPSTNTTPTQKPATTYGNGGYGSNNSGGYGQPYGSNQGGQ

Flanking regions ( +/- flanking 50bp)

AAATCGGCTCTTAAGCCTGATAAATCTAATCATAATAATGGAGCTAGAACATGGCGTGGAATCAGCCCGGTAACAACGGACAAGACCGCGACCCGTGGGGGAACCGAAACGGCGGTAATAATAACGGCGACGGGAACTCTAACGGTAATCAAGGAGGTCGGGATCGTAAAGCATCAGATCTCGATGATTTGTTCCGGAAACTGAGTGCAAAACTTGGCGGTTTCGGTGGTAAAAAAGGAGGAAACTCCTCTTCTGGGCAAAATGGCGGACCTCGTGGTAATGCTGGAAACGTATTAGTTTCTCTTGCATTAGGTGCTGTGGTTGTCGTTTGGGCTGCCAGTGGTTTTTATACCATTAAAGAAGCCGAACAAGGTGTTGTGACTCGTTTCGGTAAATTTTACCAAATCGTCGAGCCTGGTTTAAACTGGAAACCGACTTTCATTGATGAAGTTCAGCCTGTCAACGTAAAAACCATCCGTGATTTAACTACGGGTGGCATGATGTTGACATCAGATGAAAACATGGTTCAAGTTGAGATAAACGTTCAATATGTTGTCTCAGATCCAGAAGCATTTCTCTTTAATGTCACAACGCCAATGAATAGCCTAGGACAAGCGACAGACAGTGCCGTCCGTGGTGTCATTGGTCGTTCAGAAATGGAAAAGATCCTGACATCGAACCGCTCAGAAATTCGTGATCAAACCCGTCAAGAATTAGAAGAGACGATCCGCCCTTATAAAATGGGGATCTCCATTGTGGACGTCAACTTCCAAGTTGCTCGCCCACCAGAAGCGGTCAAAGCGGCATTCGATGACGTAATTGCGGCACGAGAAGAAGAGCAGAAAACCATTCGTCAGGCTGAGGCTTATAAAAACGAAGTGTTACCATTAGCGAAAGGTAACGCACAACGTATGATTGAAGAAGCAACCGCTTATAAAACGAGTGTGGTGATGAAAGCAGAAGGTGAGGTGGCGAGTTTCGCCAAAATCTTACCTGAATATCGCGCAGCACCGGAAATTACTCGTGAGCGTCTGTATATTGAAACAATGGAAAAAGTGTTGTCGAAAACACGTAAAGTCATTGCCAATGACAAAGGTAACAGTATGTTGGTTCTGCCTTTAGAGCAAATGTTACGCCAGCAACCAAAAGCGCCAACGTCAGTTAATAGTGTCACAGAGGCACCTGCGCGTATTTCAACCCCTACGCCAAGTACCAACACAACACCTACTCAGAAACCAGCAACAACTTATGGTAACGGTGGATATGGTAGCAATAATAGTGGTGGTTATGGTCAGCCTTATGGCTCTAATCAAGGAGGACAATAATCATGCGTAAAGTTATCGCTGTTGTTGCAGTTATTATTTTAGCGTTGTTG