Homologs in group_1423

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_08465 FBDBKF_08465 100.0 Morganella morganii S1 hflK FtsH protease activity modulator HflK
NLDBIP_13400 NLDBIP_13400 100.0 Morganella morganii S4 hflK FtsH protease activity modulator HflK
LHKJJB_13155 LHKJJB_13155 100.0 Morganella morganii S3 hflK FtsH protease activity modulator HflK
HKOGLL_11875 HKOGLL_11875 100.0 Morganella morganii S5 hflK FtsH protease activity modulator HflK
F4V73_RS09685 F4V73_RS09685 93.0 Morganella psychrotolerans hflK FtsH protease activity modulator HflK
PMI_RS16760 PMI_RS16760 67.6 Proteus mirabilis HI4320 hflK FtsH protease activity modulator HflK

Distribution of the homologs in the orthogroup group_1423

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1423

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0ABC7 8.84e-163 467 68 3 363 1 hflK Modulator of FtsH protease HflK Escherichia coli (strain K12)
P0ABC8 8.84e-163 467 68 3 363 3 hflK Protein HflK Escherichia coli O157:H7
P57631 8.63e-131 385 46 5 426 3 hflK Protein HflK Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Q8K914 2.78e-129 382 51 4 370 3 hflK Protein HflK Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
P44546 9.47e-127 375 48 8 410 3 hflK Protein HflK Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P40605 1.79e-111 336 47 4 381 3 hflK Protein HflK Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Q9KV09 1.8e-109 330 49 5 381 3 hflK Protein HflK Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q89A39 1.07e-79 255 36 3 353 3 hflK Protein HflK Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
O83151 1.41e-37 142 29 2 283 3 hflK Protein HflK Treponema pallidum (strain Nichols)
O51221 9.18e-30 120 27 3 279 3 hflK Protein HflK Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
P63694 1.35e-14 78 26 5 246 3 BQ2027_MB1524 Uncharacterized protein Mb1524 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P9WPR9 1.35e-14 78 26 5 246 1 Rv1488 Uncharacterized protein Rv1488 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WPR8 1.35e-14 78 26 5 246 3 MT1533.2 Uncharacterized protein MT1533.2 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
O26788 9.68e-14 75 27 4 195 3 MTH_692 Uncharacterized protein MTH_692 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
P0DKS0 5e-13 73 25 4 205 3 qmcA Protein QmcA Wigglesworthia glossinidia brevipalpis
P0AA56 1.05e-11 68 23 8 284 3 qmcA Protein QmcA Shigella flexneri
P0AA53 1.05e-11 68 23 8 284 1 qmcA Protein QmcA Escherichia coli (strain K12)
P0AA54 1.05e-11 68 23 8 284 3 qmcA Protein QmcA Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P0AA55 1.05e-11 68 23 8 284 3 qmcA Protein QmcA Escherichia coli O157:H7
Q99JB2 1.03e-08 60 20 3 213 1 Stoml2 Stomatin-like protein 2, mitochondrial Mus musculus
P72655 1.12e-08 60 21 5 278 3 slr1128 Uncharacterized protein slr1128 Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q5UP73 1.12e-08 59 25 7 211 3 MIMI_R614 Putative band 7 family protein R614 Acanthamoeba polyphaga mimivirus
Q4FZT0 1.14e-08 60 20 3 213 1 Stoml2 Stomatin-like protein 2, mitochondrial Rattus norvegicus
Q9UJZ1 1.37e-08 60 20 4 213 1 STOML2 Stomatin-like protein 2, mitochondrial Homo sapiens
O28852 1.68e-08 58 26 2 149 3 AF_1420 Uncharacterized protein AF_1420 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
H2FLJ1 2.97e-08 58 22 5 209 2 stl-1 Stomatin-like protein stl-1 Caenorhabditis elegans
Q32LL2 3.04e-08 58 20 4 213 2 STOML2 Stomatin-like protein 2, mitochondrial Bos taurus
Q9SRH6 5.24e-08 57 22 6 261 1 HIR3 Hypersensitive-induced response protein 3 Arabidopsis thaliana
O59180 6.31e-08 57 28 4 156 1 PH1511 Stomatin homolog PH1511 Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Q9V0Y1 8.31e-08 56 28 4 156 3 PYRAB06580 Stomatin homolog PYRAB06580 Pyrococcus abyssi (strain GE5 / Orsay)
Q58237 1.14e-07 55 23 5 190 3 MJ0827 Uncharacterized protein MJ0827 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q19200 1.82e-07 56 24 4 172 3 sto-1 Stomatin-1 Caenorhabditis elegans
Q19958 3.38e-07 55 23 4 179 3 sto-2 Stomatin-2 Caenorhabditis elegans
P57630 7.91e-07 54 24 12 293 3 hflC Protein HflC Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
O60121 4.49e-06 52 20 4 207 3 SPBC16G5.07c Uncharacterized protein C16G5.07c Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q8K915 4.6e-06 52 22 9 263 3 hflC Protein HflC Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Q9FHM7 4.66e-06 51 21 5 190 1 HIR4 Hypersensitive-induced response protein 4 Arabidopsis thaliana
Q27433 3.7e-05 49 22 3 168 1 mec-2 Mechanosensory protein 2 Caenorhabditis elegans
Q8TAV4 6.92e-05 48 25 5 192 1 STOML3 Stomatin-like protein 3 Homo sapiens
Q9CAR7 0.000127 47 22 8 268 1 HIR2 Hypersensitive-induced response protein 2 Arabidopsis thaliana
P27105 0.000156 47 23 5 165 1 STOM Stomatin Homo sapiens
Q6ZIV7 0.000306 46 22 8 269 1 HIR1 Hypersensitive-induced response protein 1 Oryza sativa subsp. japonica
Q6K550 0.000385 45 22 8 268 3 HIRL2 Hypersensitive-induced response protein-like protein 2 Oryza sativa subsp. japonica
Q9KV08 0.000476 45 24 5 144 3 hflC Protein HflC Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q6PE84 0.000734 45 25 4 163 1 Stoml3 Stomatin-like protein 3 Mus musculus

  • Number of RefSeq hits:

General

Source Morganella morganii S2
Locus tag EHELCC_13060
Feature type CDS
Gene hflK
Product FtsH protease activity modulator HflK
Location 89158 - 90435 (strand: -1)
Length 1278 (nucleotides) / 425 (amino acids)
In genomic island -

Contig

Accession ZDB_222
Length 162442 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_1423
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF01145 SPFH domain / Band 7 family
PF12221 Bacterial membrane protein N terminal

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0330 Posttranslational modification, protein turnover, chaperones (O) O Regulator of protease activity HflC, stomatin/prohibitin superfamily

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K04088 modulator of FtsH protease HflK - -

Protein Sequence

MAWNQPGNNGQDRDPWGSSNKGGNSDGNKGGRNRGASDLDDLFRKMSRKLGGLGGGKGGNNNGQSGGNNRPPVQFAGGRIISLAIAAVVVVWAATGFYTIKETERGVVTRFGKFSHVVQPGLNWRPTFIDRVTAVDVATVQDLATNGMMLTADENVVRVNMNVQFQVVNPEDYLFSVTNPNNSLRQAMDSAVRGVIGKFTMEKILTANRTVVRNETQKVLEETIKPYKMGIAIVDVNFQEARPPAEVQASFDDVIAARENEQQSIREAEAYSNEVLPLAKGNAQSMIESAQAYKASIVLKARGEVASFSKMLPEYRAAPDITRERLYIETMERVLSNTRKVIANDKSNSMMVLPLDQIMREQRAASQAAPAKAAATPSSAPATQAPAGRQAQNSSQNPNVPAEYNNTYDLSSSGIRGNTERTGRQ

Flanking regions ( +/- flanking 50bp)

TTTGTGCTCTTAGCCCTGAAAAACCGATCATAAAAGAGTGGAGCGAAGGCATGGCGTGGAATCAGCCCGGTAATAACGGACAGGACCGCGACCCGTGGGGGAGCAGCAATAAAGGCGGCAACTCCGACGGTAACAAAGGCGGCCGGAACCGTGGGGCATCTGATCTCGACGATCTGTTCCGGAAAATGAGCAGAAAACTCGGTGGTCTGGGTGGCGGTAAAGGCGGAAACAATAACGGGCAGTCCGGCGGGAACAATCGTCCTCCGGTACAGTTCGCGGGCGGACGTATTATCAGTCTCGCTATTGCCGCCGTTGTTGTTGTCTGGGCCGCAACCGGCTTCTATACGATTAAAGAAACGGAGCGCGGCGTGGTTACGCGTTTCGGTAAATTCAGTCATGTGGTTCAGCCGGGTCTGAACTGGAGACCGACCTTTATTGATCGCGTTACTGCGGTCGATGTGGCGACTGTCCAGGATCTGGCCACCAACGGTATGATGCTGACCGCTGACGAGAACGTGGTCCGCGTTAACATGAACGTGCAGTTCCAGGTAGTGAACCCGGAAGATTACCTCTTCAGCGTCACTAACCCGAACAACAGTCTGCGTCAGGCGATGGACAGCGCGGTGCGCGGGGTTATCGGTAAGTTCACCATGGAGAAAATCCTGACGGCGAACCGTACCGTGGTCCGTAACGAAACCCAGAAAGTCCTCGAAGAGACAATCAAGCCTTATAAAATGGGGATAGCGATTGTCGATGTCAACTTCCAGGAAGCGCGTCCGCCGGCTGAAGTTCAGGCTTCATTCGATGACGTGATTGCCGCGCGTGAAAACGAACAGCAGTCCATCCGTGAAGCGGAAGCTTACTCGAACGAAGTTCTGCCGCTGGCAAAAGGTAATGCGCAAAGTATGATCGAAAGCGCCCAGGCGTATAAAGCCAGTATCGTGCTGAAAGCGCGCGGTGAAGTGGCAAGCTTCTCGAAAATGCTGCCGGAATACCGTGCGGCACCGGATATCACCCGTGAACGTCTGTACATTGAGACAATGGAACGTGTGCTGAGCAATACCCGTAAAGTGATTGCCAATGATAAAAGCAACAGCATGATGGTGCTGCCGCTGGATCAGATTATGCGTGAGCAGAGAGCCGCCTCTCAGGCTGCACCGGCGAAAGCCGCTGCCACACCATCATCCGCCCCGGCAACACAGGCACCGGCAGGCCGTCAGGCACAAAACAGCAGCCAGAATCCGAATGTACCCGCTGAATACAACAACACGTATGATCTCAGCAGTTCGGGTATCCGTGGCAACACTGAACGCACAGGGAGACAATAATCATGCGTAAGTATTTAGCCGTTATTGTTATTCTGGTTTTAGGCGTTCTG