Homologs in group_899

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_04175 FBDBKF_04175 59.7 Morganella morganii S1 - 5-formyltetrahydrofolate cyclo-ligase
EHELCC_05465 EHELCC_05465 59.7 Morganella morganii S2 - 5-formyltetrahydrofolate cyclo-ligase
NLDBIP_05785 NLDBIP_05785 59.7 Morganella morganii S4 - 5-formyltetrahydrofolate cyclo-ligase
LHKJJB_02665 LHKJJB_02665 59.7 Morganella morganii S3 - 5-formyltetrahydrofolate cyclo-ligase
HKOGLL_06140 HKOGLL_06140 59.7 Morganella morganii S5 - 5-formyltetrahydrofolate cyclo-ligase
F4V73_RS08620 F4V73_RS08620 59.2 Morganella psychrotolerans - 5-formyltetrahydrofolate cyclo-ligase

Distribution of the homologs in the orthogroup group_899

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_899

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P44905 4.5e-74 224 56 0 183 1 HI_0858 5-formyltetrahydrofolate cyclo-ligase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P0AC28 6.89e-74 224 56 0 181 1 ygfA 5-formyltetrahydrofolate cyclo-ligase Escherichia coli (strain K12)
P0AC29 6.89e-74 224 56 0 181 3 ygfA 5-formyltetrahydrofolate cyclo-ligase Escherichia coli O157:H7
Q89AD6 1.51e-57 182 46 1 191 3 bbp_370 Uncharacterized protein bbp_370 Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Q8K9E3 3.35e-54 174 44 0 187 3 BUsg_396 Uncharacterized protein BUsg_396 Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
P54491 1.02e-22 93 30 2 185 1 yqgN Uncharacterized protein YqgN Bacillus subtilis (strain 168)
P49914 1.27e-17 80 26 4 200 1 MTHFS 5-formyltetrahydrofolate cyclo-ligase Homo sapiens
Q9D110 1.43e-17 80 25 4 200 2 Mthfs 5-formyltetrahydrofolate cyclo-ligase Mus musculus
P80405 9.38e-17 78 26 4 188 1 MTHFS 5-formyltetrahydrofolate cyclo-ligase Oryctolagus cuniculus
A0R3H2 8.79e-14 70 28 5 189 1 MSMEG_5472 5-formyltetrahydrofolate cyclo-ligase Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
Q9P7W2 6.08e-11 62 25 5 200 3 SPBC1703.08c Probable 5-formyltetrahydrofolate cyclo-ligase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P75430 9.26e-09 55 25 7 186 1 MPN_348 5-formyltetrahydrofolate cyclo-ligase Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)
Q9XWE6 1.55e-08 55 21 3 199 3 Y106G6E.4 Probable 5-formyltetrahydrofolate cyclo-ligase Caenorhabditis elegans
P47487 8.05e-08 53 24 6 183 3 MG245 5-formyltetrahydrofolate cyclo-ligase Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
P40099 1.51e-07 53 25 9 206 1 FAU1 5-formyltetrahydrofolate cyclo-ligase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q8L539 7.96e-05 45 25 11 214 1 5FCL 5-formyltetrahydrofolate cyclo-ligase, mitochondrial Arabidopsis thaliana

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS09995
Feature type CDS
Gene -
Product 5-formyltetrahydrofolate cyclo-ligase
Location 2167349 - 2167966 (strand: 1)
Length 618 (nucleotides) / 205 (amino acids)
In genomic island -

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_899
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF01812 5-formyltetrahydrofolate cyclo-ligase family

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0212 Coenzyme transport and metabolism (H) H 5-formyltetrahydrofolate cyclo-ligase

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01934 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] One carbon pool by folate
Metabolic pathways
Folate transport and metabolism		 -

Protein Sequence

MTQPPVFQQRDQIRKAIRQKRRQLTVAQQQDAAHKLSERVLHHPKVKQAKTIALFLSFDGEIDTAPLITHLWDLNKQVCLPVLHPFHRHHLLFLRYAPTTQLVKNRFNIFEPPLNVNNIIPISDIDIIFTPLVAFDESGQRLGMGGGFYDRTLENWQRQSFYPMGLAHTCQQVHSLPSADWDIPLPEIITPDKVWRFDERLIQRN

Flanking regions ( +/- flanking 50bp)

TAGAAGTGATATATTTTTATTCATACTAATTCCTTGCTGATGGATTAATCATGACACAACCCCCTGTTTTCCAGCAAAGAGATCAGATACGTAAAGCTATCCGCCAAAAACGCCGTCAACTTACTGTGGCACAACAGCAAGATGCTGCACATAAACTCTCTGAACGGGTACTCCATCATCCCAAAGTCAAGCAAGCTAAAACAATTGCCTTATTTCTCTCTTTTGACGGCGAGATTGATACCGCTCCTCTAATCACTCATTTATGGGATTTAAATAAACAGGTTTGTCTGCCTGTATTACACCCTTTTCATCGCCATCATTTACTTTTTTTACGTTACGCTCCCACCACGCAGTTAGTGAAAAATCGTTTTAATATTTTTGAGCCTCCACTCAATGTGAATAATATTATTCCAATATCTGATATTGATATTATCTTTACGCCACTGGTTGCCTTCGATGAAAGCGGTCAGCGACTCGGTATGGGCGGAGGTTTTTATGATAGAACATTAGAAAACTGGCAACGGCAGTCATTTTATCCTATGGGGCTTGCTCATACATGCCAACAAGTTCATTCGTTACCGAGCGCAGATTGGGATATACCGTTACCTGAAATTATTACACCTGATAAAGTATGGCGTTTTGATGAACGACTGATACAGAGAAATTAAGACGAGCTTTTAACGCTATCTTTGTTTTTTTATATTATTATCTTATTTTA