Homologs in group_2188

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_16490 FBDBKF_16490 59.5 Morganella morganii S1 acrA MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit
EHELCC_08355 EHELCC_08355 59.5 Morganella morganii S2 acrA MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit
NLDBIP_08680 NLDBIP_08680 59.5 Morganella morganii S4 acrA MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit
LHKJJB_05585 LHKJJB_05585 59.5 Morganella morganii S3 acrA MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit
HKOGLL_05330 HKOGLL_05330 59.5 Morganella morganii S5 acrA MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit
F4V73_RS03005 F4V73_RS03005 55.8 Morganella psychrotolerans - MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit

Distribution of the homologs in the orthogroup group_2188

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2188

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
B4EY99 0.0 827 100 0 411 3 mdtA Multidrug resistance protein MdtA Proteus mirabilis (strain HI4320)
Q7N3E3 2.61e-174 495 69 0 345 3 mdtA Multidrug resistance protein MdtA Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
A1JKX1 7.98e-172 490 59 3 416 3 mdtA Multidrug resistance protein MdtA Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
A4TMR2 2.47e-169 484 60 1 399 3 mdtA Multidrug resistance protein MdtA Yersinia pestis (strain Pestoides F)
Q1CK59 2.47e-169 484 60 1 399 3 mdtA Multidrug resistance protein MdtA Yersinia pestis bv. Antiqua (strain Nepal516)
Q8ZCW1 2.47e-169 484 60 1 399 3 mdtA Multidrug resistance protein MdtA Yersinia pestis
Q1C5M1 2.47e-169 484 60 1 399 3 mdtA Multidrug resistance protein MdtA Yersinia pestis bv. Antiqua (strain Antiqua)
B1JSD5 7.28e-169 483 59 1 406 3 mdtA Multidrug resistance protein MdtA Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
A7FG18 1.16e-168 483 60 1 399 3 mdtA Multidrug resistance protein MdtA Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Q668C7 8.49e-168 480 58 1 406 3 mdtA Multidrug resistance protein MdtA Yersinia pseudotuberculosis serotype I (strain IP32953)
B2K9L9 8.49e-168 480 58 1 406 3 mdtA Multidrug resistance protein MdtA Yersinia pseudotuberculosis serotype IB (strain PB1/+)
F2EYD8 4.92e-156 449 55 1 403 3 mdtA Multidrug resistance protein MdtA Pantoea ananatis (strain AJ13355)
C9XVZ5 5.91e-156 449 58 3 387 3 mdtA Multidrug resistance protein MdtA Cronobacter turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827 / z3032)
B7MWY7 6.89e-156 449 59 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli O81 (strain ED1a)
B7LV38 8.48e-156 449 59 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)
B7M457 9.98e-156 449 59 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli O8 (strain IAI1)
B2TYA9 1.11e-155 448 59 3 390 3 mdtA Multidrug resistance protein MdtA Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
B5YUD2 1.11e-155 448 59 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli O157:H7 (strain EC4115 / EHEC)
Q8X7J5 1.11e-155 448 59 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli O157:H7
Q0TG16 1.27e-155 448 59 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Q8CVX8 1.51e-155 448 59 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
A7ZNP7 2.34e-155 447 61 2 369 3 mdtA Multidrug resistance protein MdtA Escherichia coli O139:H28 (strain E24377A / ETEC)
B7ME86 3.24e-155 447 58 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli O45:K1 (strain S88 / ExPEC)
P76397 5.3e-155 447 58 3 390 2 mdtA Multidrug resistance protein MdtA Escherichia coli (strain K12)
A8A1U6 5.3e-155 447 58 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli O9:H4 (strain HS)
B1X7H0 5.3e-155 447 58 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain K12 / DH10B)
C4ZSG2 5.3e-155 447 58 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain K12 / MC4100 / BW2952)
B7UTB2 5.3e-155 447 58 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli O127:H6 (strain E2348/69 / EPEC)
B7NQB2 5.36e-155 447 61 2 369 3 mdtA Multidrug resistance protein MdtA Escherichia coli O7:K1 (strain IAI39 / ExPEC)
B7L9U7 8.2e-155 446 58 3 390 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain 55989 / EAEC)
D3V7P2 1.2e-154 446 56 3 403 3 mdtA Multidrug resistance protein MdtA Xenorhabdus bovienii (strain SS-2004)
B7NCB0 8.95e-154 444 60 2 369 3 mdtA Multidrug resistance protein MdtA Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
B1LNW7 9.76e-154 443 60 2 369 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain SMS-3-5 / SECEC)
A4WCC0 4.28e-153 442 55 1 402 3 mdtA Multidrug resistance protein MdtA Enterobacter sp. (strain 638)
A6TBH3 3.56e-152 439 58 0 379 3 mdtA Multidrug resistance protein MdtA Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
D2BTK6 1.77e-150 436 53 3 401 3 mdtA Multidrug resistance protein MdtA Dickeya zeae (strain Ech586)
Q6D2B2 2.34e-148 430 55 5 407 3 mdtA Multidrug resistance protein MdtA Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
Q8ZNQ3 3.24e-146 424 58 2 381 3 mdtA Multidrug resistance protein MdtA Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
B4T9U0 3.35e-146 424 58 2 383 3 mdtA Multidrug resistance protein MdtA Salmonella heidelberg (strain SL476)
C6DBC6 3.86e-146 424 55 5 409 3 mdtA Multidrug resistance protein MdtA Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Q83KI5 3.94e-146 422 62 1 339 3 mdtA Putative multidrug resistance protein MdtA Shigella flexneri
D4I6V2 6.37e-146 423 55 4 398 3 mdtA Multidrug resistance protein MdtA Erwinia amylovora (strain ATCC 49946 / CCPPB 0273 / Ea273 / 27-3)
Q8Z5F8 1.49e-145 422 58 2 383 3 mdtA Multidrug resistance protein MdtA Salmonella typhi
C0Q1F4 1.49e-145 422 58 2 383 3 mdtA Multidrug resistance protein MdtA Salmonella paratyphi C (strain RKS4594)
C5BHN6 7.18e-127 375 50 3 380 3 mdtA Multidrug resistance protein MdtA Edwardsiella ictaluri (strain 93-146)
Q8X4L0 2.16e-40 150 30 4 319 3 mdtE Multidrug resistance protein MdtE Escherichia coli O157:H7
P37636 7.22e-40 149 29 4 319 1 mdtE Multidrug resistance protein MdtE Escherichia coli (strain K12)
Q8CVL1 8.25e-40 149 29 4 319 3 mdtE Multidrug resistance protein MdtE Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Q8FWV8 4.97e-38 145 31 5 344 1 bepF Efflux pump periplasmic linker BepF Brucella suis biovar 1 (strain 1330)
P24180 1.45e-37 143 31 2 320 1 acrE Multidrug export protein AcrE Escherichia coli (strain K12)
P0AE06 2.14e-36 140 33 7 341 1 acrA Multidrug efflux pump subunit AcrA Escherichia coli (strain K12)
P0AE07 2.14e-36 140 33 7 341 3 acrA Multidrug efflux pump subunit AcrA Escherichia coli O157:H7
P43505 2.71e-36 140 30 3 335 3 mtrC Membrane fusion protein MtrC Neisseria gonorrhoeae
O31099 1.72e-32 129 29 6 322 2 srpA Solvent efflux pump periplasmic linker SrpA Pseudomonas putida
Q93PU5 2e-32 129 29 6 322 2 ttgG Toluene efflux pump periplasmic linker protein TtgG Pseudomonas putida (strain DOT-T1E)
Q8G2M7 1.43e-31 127 29 2 328 1 bepD Efflux pump periplasmic linker BepD Brucella suis biovar 1 (strain 1330)
Q9WWZ9 2.53e-31 126 30 5 319 2 ttgA Toluene efflux pump periplasmic linker protein TtgA Pseudomonas putida (strain DOT-T1E)
Q88N30 7.34e-31 125 29 6 322 1 ttgA Probable efflux pump periplasmic linker TtgA Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
P0C069 7.34e-31 125 29 6 322 1 mepA Multidrug/solvent efflux pump periplasmic linker protein MepA Pseudomonas putida
Q9KJC3 2.59e-30 123 30 5 308 2 arpA Antibiotic efflux pump periplasmic linker protein ArpA Pseudomonas putida
Q9KWV5 7.22e-30 122 28 7 327 2 ttgD Toluene efflux pump periplasmic linker protein TtgD Pseudomonas putida (strain DOT-T1E)
Q849Q9 7.22e-30 122 28 7 327 3 sepA Probable efflux pump periplasmic linker protein SepA Pseudomonas putida (strain ATCC 700007 / DSM 6899 / JCM 31910 / BCRC 17059 / LMG 24140 / F1)
P52477 7.55e-27 114 27 6 321 1 mexA Multidrug resistance protein MexA Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P75830 1.29e-17 87 26 10 396 1 macA Macrolide export protein MacA Escherichia coli (strain K12)
P64177 1.21e-16 84 26 10 396 3 macA Macrolide export protein MacA Shigella flexneri
P64176 1.21e-16 84 26 10 396 3 macA Macrolide export protein MacA Escherichia coli O157:H7
Q57500 3.18e-16 83 24 11 377 3 HI_0894 Uncharacterized protein HI_0894 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P76185 3.81e-16 81 36 2 141 3 ydhJ Uncharacterized protein YdhJ Escherichia coli (strain K12)
P58411 3.03e-15 80 28 9 343 3 macA Macrolide export protein MacA Yersinia pestis
Q88F89 1.91e-13 74 28 3 203 1 pvdR Pyoverdine export membrane fusion protein PvdR Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Q9I191 4.27e-09 61 28 3 188 1 pvdR Pyoverdine export membrane fusion protein PvdR Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9L9D4 5.04e-08 57 23 7 299 3 None UPF0194 membrane protein in asrC 5'region (Fragment) Acidithiobacillus ferridurans
Q8FAX1 2.6e-07 55 26 5 217 3 mdtN Multidrug resistance protein MdtN Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P32716 4.49e-07 55 26 5 217 2 mdtN Multidrug resistance protein MdtN Escherichia coli (strain K12)
Q83P86 5.77e-07 54 26 5 217 3 mdtN Multidrug resistance protein MdtN Shigella flexneri
Q8X5R2 1.05e-06 53 26 5 217 3 mdtN Multidrug resistance protein MdtN Escherichia coli O157:H7
Q93AA7 1.11e-06 53 26 5 226 3 YP_0975 UPF0194 membrane protein YP_0975 Yersinia pestis
B1JSP3 1.11e-06 53 26 5 226 3 YPK_2900 UPF0194 membrane protein YPK_2900 Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Q1CFT7 1.11e-06 53 26 5 226 3 YPN_2816 UPF0194 membrane protein YPN_2816 Yersinia pestis bv. Antiqua (strain Nepal516)
A7FKJ7 1.11e-06 53 26 5 226 3 YpsIP31758_2812 UPF0194 membrane protein YpsIP31758_2812 Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Q1C912 1.11e-06 53 26 5 226 3 YPA_1093 UPF0194 membrane protein YPA_1093 Yersinia pestis bv. Antiqua (strain Antiqua)
B2K8W1 1.31e-06 53 26 5 226 3 YPTS_1292 UPF0194 membrane protein YPTS_1292 Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Q66D37 1.31e-06 53 26 5 226 3 YPTB1212 UPF0194 membrane protein YPTB1212 Yersinia pseudotuberculosis serotype I (strain IP32953)
P44928 3.42e-06 52 25 7 284 3 emrA Multidrug export protein EmrA Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
A1JSL8 3.44e-06 52 24 5 226 3 YE2891 UPF0194 membrane protein YE2891 Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
C6DIM2 4.54e-06 52 26 2 161 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Q6DAH5 5.94e-06 51 26 2 161 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
B5R785 3.08e-05 49 28 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella gallinarum (strain 287/91 / NCTC 13346)
A8AIZ1 7.52e-05 48 25 7 230 3 CKO_02332 UPF0194 membrane protein CKO_02332 Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Q8ZQP0 8.3e-05 48 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q8Z879 8.3e-05 48 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella typhi
C0PX06 8.3e-05 48 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella paratyphi C (strain RKS4594)
B5QXS4 8.3e-05 48 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella enteritidis PT4 (strain P125109)
B5FP83 8.3e-05 48 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella dublin (strain CT_02021853)
Q57RE0 8.3e-05 48 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella choleraesuis (strain SC-B67)
B5F095 8.3e-05 48 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella agona (strain SL483)
B5BC09 8.83e-05 47 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella paratyphi A (strain AKU_12601)
Q5PG34 8.83e-05 47 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella paratyphi A (strain ATCC 9150 / SARB42)
A9MIT3 8.91e-05 47 27 7 230 3 ybhG UPF0194 membrane protein YbhG Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
B4TQW1 9.32e-05 47 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella schwarzengrund (strain CVM19633)
A9MSW1 9.32e-05 47 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
B4T074 9.32e-05 47 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella newport (strain SL254)
B4TC72 9.32e-05 47 27 7 224 3 ybhG UPF0194 membrane protein YbhG Salmonella heidelberg (strain SL476)
P25196 0.00013 47 21 8 323 3 nolF Nodulation protein NolF Rhizobium meliloti (strain 1021)
A7FDT5 0.000135 47 26 2 161 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
P52599 0.000278 46 22 11 366 2 emrK Probable multidrug resistance protein EmrK Escherichia coli (strain K12)
A8GK45 0.000818 44 27 1 134 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Serratia proteamaculans (strain 568)
Q0TJQ3 0.000823 44 26 7 230 3 ybhG UPF0194 membrane protein YbhG Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Q8FJN6 0.001 44 26 7 230 3 ybhG UPF0194 membrane protein YbhG Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS07730
Feature type CDS
Gene -
Product MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit
Location 1688243 - 1689478 (strand: 1)
Length 1236 (nucleotides) / 411 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_2188
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF13437 HlyD family secretion protein
PF13533 Biotin-lipoyl like

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0845 Cell wall/membrane/envelope biogenesis (M)
Defense mechanisms (V)		 MV Multidrug efflux pump subunit AcrA (membrane-fusion protein)

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K07799 membrane fusion protein, multidrug efflux system Two-component system -

Protein Sequence

MNNNKKTKKRFSLIIILLIVIAGAIAYWQYSSNNSAPPVSKDTPTANTPNRSTAGSRRPPMPPVQVATSAQEDVPQFLTALGTVKAVNSVTVTSRVEGQLMALHFTEGQQVNQGDLLAEIDPRPFEVQLAQAKGQLAKDQATLANARLDLARYQKLAKTHLVSQQELDNQAALVKQSEASISIDKAAINNAQLQLTYSKITAPISGRVGLKQVDVGNYISGGSSTPIVVINQMDPVDVLFTLPEQDLSQVILARKNNPTLPVIALDRNNKIELAQGALFSVDNQIDATTGTIKLKARFPQQESTLFPNQFVNIRLYVTTLEKAVVIPNAALQMGNEGHFVWVVDEENKVSKLAVEVASQNADKVVIASGLSANQRVVTDGVDRLTQGAKVEIVTPLAPKAKTTDPVVAEKA

Flanking regions ( +/- flanking 50bp)

TCATTTCATTTTTTCTCAATTAGCGAGTTGTCAGTAGGATCACCAACGCAATGAATAACAACAAAAAGACCAAAAAAAGATTTTCTCTTATTATCATCCTGCTTATTGTTATCGCTGGCGCTATCGCCTATTGGCAATACTCTTCAAACAACAGCGCACCTCCTGTGAGTAAAGATACCCCTACTGCGAATACACCAAATAGAAGTACAGCTGGCTCAAGACGACCACCGATGCCTCCTGTACAAGTGGCGACATCTGCACAAGAAGATGTGCCGCAATTTTTAACTGCTTTAGGTACAGTGAAAGCCGTCAATAGTGTGACCGTGACAAGCCGTGTGGAAGGGCAATTAATGGCGTTGCATTTCACCGAAGGCCAACAAGTGAATCAAGGCGATTTGTTAGCAGAAATCGACCCACGTCCTTTTGAAGTGCAATTAGCGCAAGCTAAAGGGCAATTGGCAAAAGATCAGGCCACACTGGCAAATGCGCGCCTTGATTTAGCTCGCTACCAAAAACTGGCAAAGACCCATTTGGTTTCACAACAAGAATTAGACAACCAAGCGGCTTTAGTCAAACAGTCTGAAGCCAGTATTAGTATCGATAAAGCAGCAATTAATAATGCACAATTACAATTAACCTATAGCAAAATAACGGCCCCTATTTCAGGACGGGTTGGATTAAAGCAGGTTGATGTCGGTAACTATATTTCTGGTGGCTCATCTACGCCAATTGTCGTTATTAATCAGATGGATCCTGTTGATGTGCTCTTTACATTACCAGAGCAAGATCTATCACAGGTTATCTTAGCCCGTAAAAATAACCCTACATTACCGGTTATTGCATTAGACAGAAATAATAAAATTGAATTAGCACAAGGGGCACTATTTAGTGTTGATAATCAAATTGATGCCACTACAGGGACTATCAAATTAAAAGCCCGTTTTCCTCAACAAGAAAGTACGCTATTTCCCAATCAATTTGTCAATATTCGTTTATATGTCACTACATTAGAAAAAGCGGTAGTGATCCCCAATGCAGCATTACAAATGGGAAATGAAGGACACTTTGTTTGGGTTGTTGATGAGGAAAACAAAGTCAGCAAACTCGCTGTTGAGGTTGCATCACAAAATGCAGATAAAGTTGTCATTGCCTCAGGGTTATCCGCTAATCAACGTGTTGTCACCGATGGTGTGGATAGATTAACGCAAGGTGCCAAAGTCGAGATTGTAACACCGCTGGCACCTAAAGCTAAAACCACTGATCCCGTTGTTGCGGAGAAAGCATAATGAGCGAAAAAATCCCCGCTACAGGTGGTGGGCCATCTCGTTTATTTATT