Homologs in group_1020

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_05695 FBDBKF_05695 88.9 Morganella morganii S1 gloA lactoylglutathione lyase
EHELCC_11895 EHELCC_11895 88.9 Morganella morganii S2 gloA lactoylglutathione lyase
NLDBIP_12235 NLDBIP_12235 88.9 Morganella morganii S4 gloA lactoylglutathione lyase
LHKJJB_12095 LHKJJB_12095 88.9 Morganella morganii S3 gloA lactoylglutathione lyase
HKOGLL_10710 HKOGLL_10710 88.9 Morganella morganii S5 gloA lactoylglutathione lyase
F4V73_RS03610 F4V73_RS03610 85.2 Morganella psychrotolerans gloA lactoylglutathione lyase

Distribution of the homologs in the orthogroup group_1020

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1020

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0AC83 8.18e-79 231 80 0 135 3 gloA Lactoylglutathione lyase Shigella flexneri
P0AC81 8.18e-79 231 80 0 135 1 gloA Lactoylglutathione lyase Escherichia coli (strain K12)
P0AC82 8.18e-79 231 80 0 135 3 gloA Lactoylglutathione lyase Escherichia coli O157:H7
P0A1Q2 3.41e-76 225 79 0 135 3 gloA Lactoylglutathione lyase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P0A1Q3 3.41e-76 225 79 0 135 3 gloA Lactoylglutathione lyase Salmonella typhi
P46235 3.2e-75 223 77 0 132 3 gloA Probable lactoylglutathione lyase Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
P44638 1.49e-73 218 74 0 135 1 gloA Lactoylglutathione lyase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q9KT93 2.84e-69 207 71 0 132 3 gloA Probable lactoylglutathione lyase Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
P0A0T3 1.03e-57 178 57 0 133 3 gloA Lactoylglutathione lyase Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
P0A0T2 1.03e-57 178 57 0 133 3 gloA Lactoylglutathione lyase Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)
Q55595 8.53e-57 176 60 0 131 3 gloA Probable lactoylglutathione lyase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q8W593 1.11e-49 164 56 0 132 1 At1g67280 Probable lactoylglutathione lyase, chloroplastic Arabidopsis thaliana
Q8W593 1.1e-40 141 51 0 124 1 At1g67280 Probable lactoylglutathione lyase, chloroplastic Arabidopsis thaliana
O65398 2.41e-49 162 56 0 132 1 GLX1 Lactoylglutathione lyase GLX1 Arabidopsis thaliana
O65398 7.29e-37 130 48 3 134 1 GLX1 Lactoylglutathione lyase GLX1 Arabidopsis thaliana
Q39366 2.58e-49 162 56 0 132 2 None Putative lactoylglutathione lyase Brassica oleracea var. gemmifera
Q39366 5.2e-32 117 44 4 136 2 None Putative lactoylglutathione lyase Brassica oleracea var. gemmifera
Q948T6 4.9e-40 138 48 1 133 1 GLYI-11 Lactoylglutathione lyase Oryza sativa subsp. japonica
Q948T6 2.15e-37 131 48 1 128 1 GLYI-11 Lactoylglutathione lyase Oryza sativa subsp. japonica
O04885 1.64e-27 103 39 4 156 2 GLY Lactoylglutathione lyase Brassica juncea I
P50107 7.07e-26 102 39 4 138 1 GLO1 Glyoxalase I Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P50107 1.19e-18 82 34 3 143 1 GLO1 Glyoxalase I Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q9HU72 7.53e-26 99 38 5 144 3 gloA Lactoylglutathione lyase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q42891 1.58e-25 98 36 4 156 2 GLX1 Lactoylglutathione lyase Solanum lycopersicum
O49818 6.1e-25 96 37 4 149 2 None Lactoylglutathione lyase Cicer arietinum
Q4R5F2 3.87e-24 94 35 5 151 2 GLO1 Lactoylglutathione lyase Macaca fascicularis
Q9ZS21 4.32e-24 94 36 4 149 1 GLXI Lactoylglutathione lyase Glycine max
Q8H0V3 9.48e-24 93 37 4 149 2 At1g08110 Lactoylglutathione lyase Arabidopsis thaliana
Q04760 1.29e-23 93 35 5 151 1 GLO1 Lactoylglutathione lyase Homo sapiens
Q6P7Q4 2.78e-23 92 35 5 151 1 Glo1 Lactoylglutathione lyase Rattus norvegicus
Q9CPU0 3.79e-23 92 35 5 151 1 Glo1 Lactoylglutathione lyase Mus musculus
P16635 6.58e-20 83 35 4 145 1 gloA Lactoylglutathione lyase Pseudomonas putida
Q09751 5.31e-18 80 34 4 143 1 glo1 Lactoylglutathione lyase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q09751 9.14e-16 74 32 5 141 1 glo1 Lactoylglutathione lyase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q5I0D1 9.67e-14 69 34 4 142 1 Glod4 Glyoxalase domain-containing protein 4 Rattus norvegicus
A8XX92 2.47e-13 68 29 3 143 3 glod-4 Glyoxalase 1 Caenorhabditis briggsae
Q09253 3.21e-13 67 29 3 133 2 glod-4 Glyoxalase 1 Caenorhabditis elegans
Q9CPV4 8.96e-13 66 33 4 142 1 Glod4 Glyoxalase domain-containing protein 4 Mus musculus
Q9HC38 1.06e-07 52 28 4 157 1 GLOD4 Glyoxalase domain-containing protein 4 Homo sapiens
P39586 8.01e-06 45 32 4 125 3 ywbC Uncharacterized protein YwbC Bacillus subtilis (strain 168)
O34689 0.000415 42 35 1 57 2 mhqA Putative ring-cleaving dioxygenase MhqA Bacillus subtilis (strain 168)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS06725
Feature type CDS
Gene gloA
Product lactoylglutathione lyase
Location 1469714 - 1470121 (strand: 1)
Length 408 (nucleotides) / 135 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_1020
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0346 Secondary metabolites biosynthesis, transport and catabolism (Q) Q Catechol 2,3-dioxygenase or related enzyme, vicinal oxygen chelate (VOC) family

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01759 lactoylglutathione lyase [EC:4.4.1.5] Pyruvate metabolism
Metabolic pathways		 -

Protein Sequence

MRVLHTMIRVGDLQRSIDFYTKVLGMQLLRTSENEEYKYSLAFVGYGDESSGAVIELTYNWGVTSYEMGTAFGHVALGVDDVAATCEAIRQAGGNVTREAGPVKGGTTIIAFVEDPDGYKIELIENKSASQALGN

Flanking regions ( +/- flanking 50bp)

CATCAGTTTATACTGTCGGGTGTCATATTTAACAAACACGAGAGGTTTATATGCGAGTACTTCATACCATGATCCGTGTAGGCGATTTACAACGCTCTATCGATTTTTATACCAAAGTTTTAGGTATGCAACTTCTACGCACCAGTGAGAATGAGGAATATAAATACTCGTTGGCTTTTGTTGGCTATGGTGATGAAAGTAGCGGTGCTGTTATTGAATTAACCTATAACTGGGGTGTGACTAGCTACGAAATGGGGACTGCATTTGGCCATGTTGCATTAGGGGTTGATGATGTAGCTGCAACTTGTGAGGCTATCCGTCAAGCGGGGGGTAACGTTACCCGTGAAGCAGGCCCTGTTAAAGGTGGTACAACAATTATCGCCTTTGTAGAAGATCCTGATGGATATAAAATTGAATTAATCGAAAACAAAAGTGCCAGTCAAGCTCTGGGTAACTAAATATTAGTAAAACCAGAAAGGCATTGTATTGCTTTTCTGGTTCCTGATTA