Homologs in group_1020

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_05695 FBDBKF_05695 100.0 Morganella morganii S1 gloA lactoylglutathione lyase
NLDBIP_12235 NLDBIP_12235 100.0 Morganella morganii S4 gloA lactoylglutathione lyase
LHKJJB_12095 LHKJJB_12095 100.0 Morganella morganii S3 gloA lactoylglutathione lyase
HKOGLL_10710 HKOGLL_10710 100.0 Morganella morganii S5 gloA lactoylglutathione lyase
F4V73_RS03610 F4V73_RS03610 91.1 Morganella psychrotolerans gloA lactoylglutathione lyase
PMI_RS06725 PMI_RS06725 88.9 Proteus mirabilis HI4320 gloA lactoylglutathione lyase

Distribution of the homologs in the orthogroup group_1020

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1020

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0AC83 3.18e-79 233 80 0 135 3 gloA Lactoylglutathione lyase Shigella flexneri
P0AC81 3.18e-79 233 80 0 135 1 gloA Lactoylglutathione lyase Escherichia coli (strain K12)
P0AC82 3.18e-79 233 80 0 135 3 gloA Lactoylglutathione lyase Escherichia coli O157:H7
P0A1Q2 7.43e-76 224 77 0 135 3 gloA Lactoylglutathione lyase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P0A1Q3 7.43e-76 224 77 0 135 3 gloA Lactoylglutathione lyase Salmonella typhi
P44638 1.81e-74 220 74 0 135 1 gloA Lactoylglutathione lyase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P46235 3e-73 218 75 0 132 3 gloA Probable lactoylglutathione lyase Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Q9KT93 2.81e-68 205 71 0 132 3 gloA Probable lactoylglutathione lyase Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
P0A0T3 5.99e-59 181 60 0 128 3 gloA Lactoylglutathione lyase Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
P0A0T2 5.99e-59 181 60 0 128 3 gloA Lactoylglutathione lyase Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)
Q55595 1.14e-58 180 63 0 128 3 gloA Probable lactoylglutathione lyase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q8W593 2.92e-48 161 57 0 125 1 At1g67280 Probable lactoylglutathione lyase, chloroplastic Arabidopsis thaliana
Q8W593 5.47e-38 134 49 0 124 1 At1g67280 Probable lactoylglutathione lyase, chloroplastic Arabidopsis thaliana
O65398 1.34e-46 155 55 0 124 1 GLX1 Lactoylglutathione lyase GLX1 Arabidopsis thaliana
O65398 8.03e-37 129 50 3 128 1 GLX1 Lactoylglutathione lyase GLX1 Arabidopsis thaliana
Q39366 3.73e-46 154 54 0 124 2 None Putative lactoylglutathione lyase Brassica oleracea var. gemmifera
Q39366 1.38e-32 119 46 4 130 2 None Putative lactoylglutathione lyase Brassica oleracea var. gemmifera
Q948T6 1.76e-38 134 47 1 126 1 GLYI-11 Lactoylglutathione lyase Oryza sativa subsp. japonica
Q948T6 3.1e-36 128 45 1 128 1 GLYI-11 Lactoylglutathione lyase Oryza sativa subsp. japonica
O49818 1.5e-27 103 39 4 151 2 None Lactoylglutathione lyase Cicer arietinum
O04885 1.75e-27 103 39 4 156 2 GLY Lactoylglutathione lyase Brassica juncea I
Q42891 3.28e-27 102 38 4 156 2 GLX1 Lactoylglutathione lyase Solanum lycopersicum
Q9HU72 1.73e-26 100 39 5 144 3 gloA Lactoylglutathione lyase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9ZS21 1.99e-26 100 37 4 151 1 GLXI Lactoylglutathione lyase Glycine max
Q4R5F2 1.59e-25 98 38 5 150 2 GLO1 Lactoylglutathione lyase Macaca fascicularis
P50107 3.32e-25 100 41 4 136 1 GLO1 Glyoxalase I Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P50107 1.45e-18 82 35 3 143 1 GLO1 Glyoxalase I Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q04760 5.39e-25 96 38 5 150 1 GLO1 Lactoylglutathione lyase Homo sapiens
Q6P7Q4 1.06e-24 96 38 5 150 1 Glo1 Lactoylglutathione lyase Rattus norvegicus
Q9CPU0 1.29e-24 95 36 4 144 1 Glo1 Lactoylglutathione lyase Mus musculus
Q8H0V3 1.54e-24 95 37 4 156 2 At1g08110 Lactoylglutathione lyase Arabidopsis thaliana
P16635 1.31e-20 85 36 4 145 1 gloA Lactoylglutathione lyase Pseudomonas putida
Q09751 3.7e-17 78 33 6 142 1 glo1 Lactoylglutathione lyase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q09751 4.18e-17 78 32 4 144 1 glo1 Lactoylglutathione lyase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A8XX92 4.23e-12 64 30 3 133 3 glod-4 Glyoxalase 1 Caenorhabditis briggsae
Q09253 8.99e-12 63 28 3 133 2 glod-4 Glyoxalase 1 Caenorhabditis elegans
Q09253 0.000751 41 26 5 129 2 glod-4 Glyoxalase 1 Caenorhabditis elegans
Q5I0D1 8.98e-10 58 32 3 133 1 Glod4 Glyoxalase domain-containing protein 4 Rattus norvegicus
Q9CPV4 5.34e-09 56 32 3 133 1 Glod4 Glyoxalase domain-containing protein 4 Mus musculus
P39586 8.93e-08 50 31 2 124 3 ywbC Uncharacterized protein YwbC Bacillus subtilis (strain 168)
Q9HC38 1.01e-05 47 28 4 153 1 GLOD4 Glyoxalase domain-containing protein 4 Homo sapiens

  • Number of RefSeq hits:

General

Source Morganella morganii S2
Locus tag EHELCC_11895
Feature type CDS
Gene gloA
Product lactoylglutathione lyase
Location 35454 - 35861 (strand: -1)
Length 408 (nucleotides) / 135 (amino acids)

Contig

Accession ZDB_221
Length 181491 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_1020
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0346 Secondary metabolites biosynthesis, transport and catabolism (Q) Q Catechol 2,3-dioxygenase or related enzyme, vicinal oxygen chelate (VOC) family

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01759 lactoylglutathione lyase [EC:4.4.1.5] Pyruvate metabolism
Metabolic pathways		 -

Protein Sequence

MRVLHTMLRVGDMQRSVDFYTKVLGMRLLRTSENPEYKYSLAFVGYSDESEGSVIELTYNWGTDSYEMGTAFGHIALGVDDVAATCDAIRKAGGNVTREAGPVKGGTTIIAFVEDPDGYKIELIENKSAGAALGN

Flanking regions ( +/- flanking 50bp)

GTGTGAGCCATTACTGATAAATAACTGAAAGCACTCTGAGAGGTTACTTTATGCGTGTACTCCATACCATGCTCCGCGTGGGTGATATGCAACGTTCTGTCGATTTTTACACTAAGGTTCTCGGCATGCGTTTACTGCGCACCAGTGAAAACCCGGAATATAAATATTCTCTGGCTTTCGTGGGTTACAGTGACGAAAGTGAAGGCTCTGTTATCGAACTGACGTATAACTGGGGCACGGATTCCTATGAGATGGGAACGGCATTCGGCCATATCGCACTCGGCGTGGATGATGTCGCGGCGACCTGTGATGCTATCCGCAAAGCGGGCGGCAATGTGACCCGTGAAGCCGGCCCGGTTAAGGGCGGTACCACCATTATCGCTTTTGTGGAAGACCCGGACGGCTATAAGATTGAATTAATTGAAAATAAAAGTGCCGGGGCTGCTCTCGGTAACTGAGTGACTCCGTAAGAAGGATCCGAACGATCCTTCTTTTCCGGCTCAGCCCT