Homologs in group_181

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8 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_06330 FBDBKF_06330 26.7 Morganella morganii S1 tolC outer membrane channel protein TolC
EHELCC_09375 EHELCC_09375 26.7 Morganella morganii S2 tolC outer membrane channel protein TolC
NLDBIP_09755 NLDBIP_09755 26.7 Morganella morganii S4 tolC outer membrane channel protein TolC
LHKJJB_08000 LHKJJB_08000 26.7 Morganella morganii S3 tolC outer membrane channel protein TolC
HKOGLL_07550 HKOGLL_07550 26.7 Morganella morganii S5 tolC outer membrane channel protein TolC
F4V73_RS09460 F4V73_RS09460 16.8 Morganella psychrotolerans - TolC family protein
F4V73_RS15590 F4V73_RS15590 26.2 Morganella psychrotolerans tolC outer membrane channel protein TolC
PMI_RS11620 PMI_RS11620 26.6 Proteus mirabilis HI4320 tolC outer membrane channel protein TolC

Distribution of the homologs in the orthogroup group_181

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_181

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q51397 7.38e-16 83 25 10 420 1 oprJ Outer membrane protein OprJ Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P02930 3.24e-10 65 24 9 413 1 tolC Outer membrane protein TolC Escherichia coli (strain K12)
Q9KWV3 5.55e-10 65 23 9 481 2 ttgF Toluene efflux pump outer membrane protein TtgF Pseudomonas putida (strain DOT-T1E)
Q849R1 5.55e-10 65 23 9 481 3 sepC Probable efflux pump outer membrane protein SepC Pseudomonas putida (strain ATCC 700007 / DSM 6899 / JCM 31910 / BCRC 17059 / LMG 24140 / F1)
Q9ZHD2 9.01e-10 64 21 11 427 3 silC Probable outer membrane lipoprotein SilC Salmonella typhimurium
Q2EHL7 9.15e-09 61 21 3 246 1 tdeA Toxin and drug export protein A Aggregatibacter actinomycetemcomitans
Q93PU3 1.08e-08 60 23 12 468 2 ttgI Toluene efflux pump outer membrane protein TtgI Pseudomonas putida (strain DOT-T1E)
O31101 1.08e-08 60 23 12 468 2 srpC Solvent efflux pump outer membrane protein SrpC Pseudomonas putida
Q9WWZ8 8.22e-08 58 22 15 490 2 ttgC Toluene efflux pump outer membrane protein TtgC Pseudomonas putida (strain DOT-T1E)
Q88N32 1.17e-07 57 22 15 490 1 ttgC Probable efflux pump outer membrane protein TtgC Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
P0C071 1.17e-07 57 22 15 490 1 mepC Multidrug/solvent efflux pump outer membrane protein MepC Pseudomonas putida
Q9KJC1 1.17e-07 57 22 15 490 2 arpC Antibiotic efflux pump outer membrane protein ArpC Pseudomonas putida
Q54001 2.24e-07 57 23 9 410 1 tolC Outer membrane protein TolC Salmonella enteritidis
P0DKY0 1.75e-06 53 20 5 399 3 cyaE Protein CyaE Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
J7RET5 1.75e-06 53 20 5 399 3 cyaE Protein CyaE Bordetella pertussis (strain ATCC 9797 / DSM 5571 / CCUG 30873 / LMG 14455 / NCTC 10739 / 18323)
Q8X5R9 1.77e-06 53 20 6 309 3 mdtP Multidrug resistance outer membrane protein MdtP Escherichia coli O157:H7
Q8XBY3 1.85e-06 53 20 12 481 3 cusC Cation efflux system protein CusC Escherichia coli O157:H7
Q8CVH8 2.03e-06 53 20 6 309 3 mdtP Multidrug resistance outer membrane protein MdtP Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P77211 4.41e-06 52 21 8 332 1 cusC Cation efflux system protein CusC Escherichia coli (strain K12)
Q83P87 6.44e-06 52 19 6 309 3 mdtP Multidrug resistance outer membrane protein MdtP Shigella flexneri
Q8CWA4 9.82e-06 51 21 8 332 3 cusC Cation efflux system protein CusC Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P32714 1.15e-05 51 20 6 309 3 mdtP Multidrug resistance outer membrane protein MdtP Escherichia coli (strain K12)
P45217 1.78e-05 50 19 11 397 3 HI_1462 Uncharacterized protein HI_1462 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q51487 4.81e-05 49 23 16 487 1 oprM Outer membrane protein OprM Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9K2Y1 8.6e-05 48 22 12 423 1 tolC Outer membrane protein TolC Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS06115
Feature type CDS
Gene -
Product TolC family protein
Location 1341296 - 1342771 (strand: 1)
Length 1476 (nucleotides) / 491 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_181
Orthogroup size 9
N. genomes 7

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Genomic region

Domains

PF02321 Outer membrane efflux protein

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG1538 Cell wall/membrane/envelope biogenesis (M) M Outer membrane protein TolC

Protein Sequence

MMIKSAINHKKYILSSWLSLLLVGCIDTSDYGKYSAQQPMPYNNTNYMAASEQYLATPQQEQTTKTSYGLAELIDLGQQNNPETRIAWLLAKKSATDIGMVESTYLPIITATALAGYQRGKVDLPANPIVDDIKTSNSAFIPALTFRWLIFDFGKRGALADAAKHASLATNLNFNLMHQKIIHDVSVAYFSYGAALKKVTLTQEALQRSKDILYAIEQKRARGLATVLDVALAKQQVAQVELQHVLAKGHEKDQYQLLLSAIGVSPFEKIKVNYDNDARLPDDISPLTHDVIKKALSQRPDILAHYELEQAALKTARSVESDYFPKVYLAGALAGGSGHFDVQGLPEISQRTSSSNILIGVSIPLYEGGMRQSRMSNAQSDIQLAQENLRKSQDTAIKEISLSENALRSALEANKAAKNLVDTAQLSYTASVDFFNNGLGTVTEINTAEIALLNAQLSHIDAYTGSLIAAVDLAFALGDIDQGLPNIHLDK

Flanking regions ( +/- flanking 50bp)

CCCATCAATGAAAGAGAACAAGTATTTAAACAGTTAATAAGAGAAAATAGATGATGATAAAATCGGCCATTAATCATAAAAAATATATTCTATCATCGTGGTTAAGTTTATTACTTGTTGGATGTATTGATACTAGCGATTATGGGAAATACTCAGCACAACAACCGATGCCTTATAATAATACAAACTATATGGCAGCTTCTGAGCAATACCTCGCCACACCTCAGCAAGAGCAAACCACTAAAACGAGCTATGGATTGGCCGAGCTTATCGATCTTGGTCAGCAAAATAATCCTGAAACACGGATTGCTTGGTTATTAGCGAAAAAATCAGCCACCGATATTGGTATGGTAGAAAGCACTTATTTGCCGATTATTACCGCAACGGCATTGGCAGGCTATCAAAGAGGAAAAGTAGATTTACCCGCCAATCCAATTGTTGATGATATTAAAACATCAAACAGTGCTTTTATTCCAGCGTTAACCTTTAGATGGCTTATTTTTGACTTCGGCAAACGAGGAGCTTTAGCCGATGCCGCTAAACATGCTTCTTTGGCAACAAACCTTAATTTTAATCTGATGCATCAAAAAATAATTCATGATGTTTCTGTTGCCTATTTTAGTTATGGTGCGGCCCTTAAAAAAGTCACTCTTACCCAAGAGGCACTGCAAAGAAGCAAAGATATTTTATATGCCATAGAGCAAAAACGTGCGCGGGGATTAGCAACCGTATTAGATGTTGCTTTAGCCAAACAACAAGTTGCCCAAGTAGAATTACAACATGTGTTAGCTAAAGGTCATGAAAAAGATCAATATCAGTTATTACTGTCTGCAATAGGTGTCTCTCCCTTTGAAAAGATAAAAGTGAATTATGATAATGACGCGCGCTTACCTGATGATATTTCCCCATTGACTCACGATGTGATAAAAAAAGCGTTATCACAACGCCCTGATATTTTAGCTCACTATGAATTAGAGCAAGCGGCATTAAAAACGGCACGCTCTGTTGAATCTGACTATTTTCCTAAAGTGTATCTCGCCGGTGCTCTTGCTGGTGGTTCGGGGCATTTTGATGTTCAGGGGTTACCTGAAATTAGCCAACGAACTTCATCGTCGAATATTTTAATTGGCGTGAGTATTCCCTTATATGAAGGGGGCATGCGTCAGTCGCGAATGAGCAATGCTCAATCAGATATCCAATTAGCACAAGAAAATTTGCGCAAAAGCCAAGATACGGCAATCAAAGAGATCTCTCTCAGTGAGAATGCGTTAAGATCGGCCCTTGAAGCAAACAAAGCGGCTAAAAATCTCGTTGATACCGCACAATTAAGTTATACCGCCAGTGTCGATTTTTTTAACAATGGACTAGGTACAGTAACGGAGATTAATACCGCAGAAATTGCACTATTAAATGCACAACTCTCACATATAGATGCTTATACAGGCTCATTAATTGCCGCAGTAGATTTAGCCTTTGCTTTAGGGGATATTGATCAGGGCTTACCTAATATACACCTTGATAAATAGAGATAATCACCTTATAAAAAGGGCTGCCTATCAAATAATAAAGCAATAGA