Homologs in group_302

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7 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_07975 FBDBKF_07975 57.9 Morganella morganii S1 - Ca2+-binding protein, RTX toxin-related
EHELCC_13805 EHELCC_13805 57.9 Morganella morganii S2 - Ca2+-binding protein, RTX toxin-related
NLDBIP_14250 NLDBIP_14250 57.9 Morganella morganii S4 - Ca2+-binding protein, RTX toxin-related
LHKJJB_08600 LHKJJB_08600 57.9 Morganella morganii S3 - Ca2+-binding protein, RTX toxin-related
HKOGLL_08150 HKOGLL_08150 57.9 Morganella morganii S5 - Ca2+-binding protein, RTX toxin-related
F4V73_RS13010 F4V73_RS13010 58.7 Morganella psychrotolerans - serralysin family metalloprotease
F4V73_RS16265 F4V73_RS16265 30.3 Morganella psychrotolerans - calcium-binding protein

Distribution of the homologs in the orthogroup group_302

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_302

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q11137 0.0 991 99 0 491 3 zapA Serralysin Proteus mirabilis
P23694 5.95e-143 422 50 7 463 1 None Serralysin Serratia marcescens
P07268 1.05e-142 421 50 7 463 1 None Serralysin Serratia marcescens (strain ATCC 21074 / E-15)
P19144 4.01e-132 394 47 10 463 1 prtC Serralysin C Dickeya chrysanthemi
Q07295 7.67e-128 383 47 10 463 1 prtA Serralysin A Dickeya chrysanthemi
P16317 8.49e-124 372 48 12 463 1 prtC Serralysin C Dickeya chrysanthemi
Q03023 1.34e-122 370 46 12 475 1 aprA Serralysin Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q1ID47 4.43e-122 369 47 11 464 1 aprA Metalloprotease AprA Pseudomonas entomophila (strain L48)
P16316 1.28e-120 365 46 14 471 1 prtB Serralysin B Dickeya chrysanthemi
Q07162 1.22e-116 354 45 11 464 1 prtG Serralysin G Dickeya chrysanthemi
A0A0C5CJR8 8.9e-110 337 44 11 482 1 aprA Metallopeptidase AprA Pseudomonas marginalis
Q84F70 2.45e-108 333 50 8 409 3 prtA1 Serralysin Photorhabdus luminescens
Q7N8R3 1.08e-107 331 50 8 409 3 prtA Serralysin Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
P82115 1.28e-105 326 46 10 459 1 prtA Serralysin Photorhabdus sp. (strain Az29)
Q44494 3.66e-11 69 43 1 94 1 algE1 Mannuronan C5-epimerase AlgE1 Azotobacter vinelandii
Q44494 1.26e-08 61 42 2 97 1 algE1 Mannuronan C5-epimerase AlgE1 Azotobacter vinelandii
Q44494 2.52e-08 60 38 1 92 1 algE1 Mannuronan C5-epimerase AlgE1 Azotobacter vinelandii
Q44494 5.56e-08 59 42 1 85 1 algE1 Mannuronan C5-epimerase AlgE1 Azotobacter vinelandii
Q44496 6.89e-11 68 38 4 136 3 algE3 Mannuronan C5-epimerase AlgE3 Azotobacter vinelandii
Q44496 1.06e-09 65 43 1 90 3 algE3 Mannuronan C5-epimerase AlgE3 Azotobacter vinelandii
Q44496 5.06e-09 62 41 1 87 3 algE3 Mannuronan C5-epimerase AlgE3 Azotobacter vinelandii
Q44496 2.63e-08 60 34 3 134 3 algE3 Mannuronan C5-epimerase AlgE3 Azotobacter vinelandii
Q44496 6.79e-08 59 38 3 116 3 algE3 Mannuronan C5-epimerase AlgE3 Azotobacter vinelandii
Q44496 5.54e-06 53 33 2 110 3 algE3 Mannuronan C5-epimerase AlgE3 Azotobacter vinelandii
Q44496 1.22e-05 52 43 1 72 3 algE3 Mannuronan C5-epimerase AlgE3 Azotobacter vinelandii
Q44492 3.12e-10 66 41 2 104 2 algE5 Mannuronan C5-epimerase AlgE5 Azotobacter vinelandii
Q44492 1.12e-07 58 36 2 100 2 algE5 Mannuronan C5-epimerase AlgE5 Azotobacter vinelandii
Q44492 2.75e-07 57 34 4 135 2 algE5 Mannuronan C5-epimerase AlgE5 Azotobacter vinelandii
Q44492 9.68e-06 52 41 1 72 2 algE5 Mannuronan C5-epimerase AlgE5 Azotobacter vinelandii
Q44495 7.59e-09 62 43 1 90 1 algE2 Mannuronan C5-epimerase AlgE2 Azotobacter vinelandii
Q44495 1.49e-07 57 41 2 97 1 algE2 Mannuronan C5-epimerase AlgE2 Azotobacter vinelandii
Q44495 1.12e-06 55 35 1 87 1 algE2 Mannuronan C5-epimerase AlgE2 Azotobacter vinelandii
Q44495 1.09e-05 52 43 1 71 1 algE2 Mannuronan C5-epimerase AlgE2 Azotobacter vinelandii
Q9ZFG9 8.72e-09 62 38 1 88 1 algE7 Alginate lyase 7 Azotobacter vinelandii
Q9ZFG9 3.4e-08 60 36 2 108 1 algE7 Alginate lyase 7 Azotobacter vinelandii
Q9ZFG9 2.53e-06 53 38 1 85 1 algE7 Alginate lyase 7 Azotobacter vinelandii
Q9ZFH0 4.22e-08 59 35 3 108 1 algE6 Mannuronan C5-epimerase AlgE6 Azotobacter vinelandii
Q9ZFH0 8.14e-08 58 41 1 85 1 algE6 Mannuronan C5-epimerase AlgE6 Azotobacter vinelandii
P0C085 4.85e-08 59 50 0 57 3 lktA Leukotoxin Mannheimia haemolytica
Q9EV27 4.85e-08 59 50 0 57 3 lktA Leukotoxin Mannheimia haemolytica
Q9EV33 5.07e-08 59 50 0 57 3 lktA Leukotoxin Mannheimia haemolytica
Q9EV31 5.07e-08 59 50 0 57 3 lktA Leukotoxin Mannheimia haemolytica
P55117 5.16e-08 59 50 0 57 3 lktA Leukotoxin Bibersteinia trehalosi
Q9ETX2 5.2e-08 59 50 0 57 3 lktA Leukotoxin Mannheimia glucosida
Q9EV32 5.34e-08 59 50 0 57 3 lktA Leukotoxin Mannheimia haemolytica
P0DKX7 7.13e-08 59 50 0 59 1 cya Bifunctional hemolysin/adenylate cyclase Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
P0DKX7 8.84e-08 58 50 0 54 1 cya Bifunctional hemolysin/adenylate cyclase Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
P0DKX7 3.96e-06 53 37 5 130 1 cya Bifunctional hemolysin/adenylate cyclase Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
J7QLC0 7.13e-08 59 50 0 59 1 cya Bifunctional hemolysin/adenylate cyclase Bordetella pertussis (strain ATCC 9797 / DSM 5571 / CCUG 30873 / LMG 14455 / NCTC 10739 / 18323)
J7QLC0 8.84e-08 58 50 0 54 1 cya Bifunctional hemolysin/adenylate cyclase Bordetella pertussis (strain ATCC 9797 / DSM 5571 / CCUG 30873 / LMG 14455 / NCTC 10739 / 18323)
J7QLC0 3.96e-06 53 37 5 130 1 cya Bifunctional hemolysin/adenylate cyclase Bordetella pertussis (strain ATCC 9797 / DSM 5571 / CCUG 30873 / LMG 14455 / NCTC 10739 / 18323)
Q9EV30 7.54e-08 58 50 0 57 3 lktA Leukotoxin Mannheimia haemolytica
Q57506 8.92e-08 58 50 0 54 3 cya Bifunctional hemolysin/adenylate cyclase Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Q57506 3.42e-07 57 49 0 59 3 cya Bifunctional hemolysin/adenylate cyclase Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Q57506 7.48e-06 52 41 3 91 3 cya Bifunctional hemolysin/adenylate cyclase Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Q57506 0.001 45 38 0 59 3 cya Bifunctional hemolysin/adenylate cyclase Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Q9EV29 1.55e-07 57 49 0 57 3 lktA Leukotoxin Mannheimia haemolytica
Q9EV34 1.57e-07 57 49 0 57 3 lktA Leukotoxin Mannheimia haemolytica
P0C083 1.61e-07 57 49 0 57 3 lktA Leukotoxin Mannheimia haemolytica
P0C084 1.61e-07 57 49 0 57 3 lktA Leukotoxin Mannheimia haemolytica
Q7BHI8 1.67e-07 57 49 0 57 1 lktA Leukotoxin Mannheimia haemolytica
P16535 1.67e-07 57 49 0 57 3 lktA Leukotoxin Mannheimia haemolytica
P55118 2.22e-07 57 49 0 57 3 lktA Leukotoxin Mannheimia haemolytica
A1YKW7 2.6e-07 57 45 0 57 1 rtxA Cytolysin RtxA Kingella kingae
A1YKW7 0.000354 47 45 0 48 1 rtxA Cytolysin RtxA Kingella kingae
Q44493 4.66e-07 55 34 1 106 1 algE4 Mannuronan C5-epimerase AlgE4 Azotobacter vinelandii
P55126 5.35e-07 56 28 6 201 3 frpA Iron-regulated protein FrpA Neisseria meningitidis serogroup C
Q9K0K9 1.39e-06 55 47 0 57 3 frpA Iron-regulated protein FrpA Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
Q9K0K9 3.64e-06 53 47 0 55 3 frpA Iron-regulated protein FrpA Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
Q9JYV5 1.88e-06 54 47 0 57 3 frpC Iron-regulated protein FrpC Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
Q9JYV5 5e-06 53 47 0 55 3 frpC Iron-regulated protein FrpC Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
Q9JYV5 5e-06 53 47 0 55 3 frpC Iron-regulated protein FrpC Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
Q9JYV5 5e-06 53 47 0 55 3 frpC Iron-regulated protein FrpC Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
P15377 3.91e-06 53 48 0 56 3 apxIIA RTX-II toxin determinant A Actinobacillus pleuropneumoniae
Q00951 4.01e-06 53 48 0 56 3 appA Hemolysin Actinobacillus suis
P55127 4.91e-06 53 47 0 55 1 frpC Iron-regulated protein FrpC Neisseria meningitidis serogroup C
P55127 5.04e-06 53 47 0 55 1 frpC Iron-regulated protein FrpC Neisseria meningitidis serogroup C
P55127 5.04e-06 53 47 0 55 1 frpC Iron-regulated protein FrpC Neisseria meningitidis serogroup C
P55127 5.04e-06 53 47 0 55 1 frpC Iron-regulated protein FrpC Neisseria meningitidis serogroup C
P16462 9.24e-06 52 46 0 49 1 ltxA Leukotoxin Aggregatibacter actinomycetemcomitans
P16462 0.000235 47 48 0 50 1 ltxA Leukotoxin Aggregatibacter actinomycetemcomitans
P16462 0.000393 47 36 0 57 1 ltxA Leukotoxin Aggregatibacter actinomycetemcomitans
P55131 4.58e-05 50 47 0 51 3 apxIIIA RTX-III toxin determinant A from serotype 8 Actinobacillus pleuropneumoniae
P55131 7.67e-05 49 46 0 50 3 apxIIIA RTX-III toxin determinant A from serotype 8 Actinobacillus pleuropneumoniae
P55131 0.00013 48 40 1 67 3 apxIIIA RTX-III toxin determinant A from serotype 8 Actinobacillus pleuropneumoniae
Q9RCG8 4.73e-05 50 47 0 51 3 paxA Exotoxin PaxA Pasteurella aerogenes
Q9RCG8 0.000171 48 46 0 49 3 paxA Exotoxin PaxA Pasteurella aerogenes
P55130 5.3e-05 49 47 0 51 3 apxIIIA RTX-III toxin determinant A from serotype 2 Actinobacillus pleuropneumoniae
P55130 0.000105 48 46 0 50 3 apxIIIA RTX-III toxin determinant A from serotype 2 Actinobacillus pleuropneumoniae
P55130 0.000138 48 40 1 67 3 apxIIIA RTX-III toxin determinant A from serotype 2 Actinobacillus pleuropneumoniae
P08715 5.89e-05 49 37 4 91 1 hlyA Hemolysin, plasmid Escherichia coli
P09983 8.46e-05 49 37 4 91 1 hlyA Hemolysin, chromosomal Escherichia coli
P55129 8.68e-05 48 39 1 68 3 apxIA RTX-I toxin determinant A from serotypes 5/10 Actinobacillus pleuropneumoniae
P55129 0.000305 47 46 0 49 3 apxIA RTX-I toxin determinant A from serotypes 5/10 Actinobacillus pleuropneumoniae
P55129 0.000422 47 47 0 51 3 apxIA RTX-I toxin determinant A from serotypes 5/10 Actinobacillus pleuropneumoniae
P55128 9.54e-05 48 39 1 68 1 apxIA RTX-I toxin determinant A from serotypes 1/9 Actinobacillus pleuropneumoniae
P55128 0.000347 47 46 0 49 1 apxIA RTX-I toxin determinant A from serotypes 1/9 Actinobacillus pleuropneumoniae
P55128 0.000485 46 47 0 51 1 apxIA RTX-I toxin determinant A from serotypes 1/9 Actinobacillus pleuropneumoniae

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS01355
Feature type CDS
Gene -
Product serralysin family metalloprotease
Location 328957 - 330432 (strand: -1)
Length 1476 (nucleotides) / 491 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_302
Orthogroup size 8
N. genomes 7

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Genomic region

Domains

PF00353 RTX calcium-binding nonapeptide repeat (4 copies)
PF00413 Matrixin
PF08548 Peptidase M10 serralysin C terminal

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG2931 Secondary metabolites biosynthesis, transport and catabolism (Q) Q Ca2+-binding protein, RTX toxin-related

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01406 serralysin [EC:3.4.24.40] Cationic antimicrobial peptide (CAMP) resistance -

Virulence factor Annotation(s)

VF gene ID Protein VF ID Category
VFG043807 serralysin family metalloprotease VF1332 Exotoxin

Protein Sequence

MGSFLLKKAVGLSNISDLLDKSGIFYNYSTKVLPSFDYDTAGKHIAREDSTWNGKYVIGQPAEVTYSFPKWEGKFNQFGNKNPYEFNELQKEHARKSLDAWSDIANIKFTEVAVGNVDGMKASDVKTDITFGNIYDPNGTFQAYATLPNTYAYGKDLSGQAWFSDYHYAGNTTPELGNYGRLTIIHEIGHTLGLMHPGDYNAGQNVPGYLKSDYAEDSRQYTVMSYWDEYETGAHFQGAYAGAPLLHDISAMQYLYGANTTTRTGDDVYGFNSNTGIDYYTATDSNDKLIFSVWDSGGNDTFDFSGFYQDQLIDLRAGNFSDVGGLQKNVSIAQNVTIENAIGGFGNDIIHGNDADNTLIGGEGDDIIYGHSGNNTIYGGRGQDTLHGGTGSNTFIYKEIADSLVSAADKIMDFKTGIDKIDLSTLIQDTFSSKILNFVDNFTGNAGEATLSYNEVTNASELAINAYGYNYNPDFKIDIVGFVNYETDFIV

Flanking regions ( +/- flanking 50bp)

ATTTTCAGTATGAAAATAAACTTAACCTAAATTTATATCTGGAGGATATTATGGGATCTTTTTTATTAAAAAAAGCCGTTGGGTTATCTAATATTTCTGATTTATTAGATAAAAGCGGGATCTTCTATAACTATTCAACCAAAGTATTACCTTCTTTTGATTATGATACCGCAGGAAAACATATAGCCCGTGAAGATTCCACTTGGAATGGCAAATATGTTATTGGGCAACCCGCTGAGGTGACTTATTCATTCCCAAAATGGGAAGGCAAATTTAATCAATTTGGTAATAAGAATCCTTATGAATTTAATGAATTACAAAAAGAGCATGCAAGAAAATCTTTAGATGCATGGTCTGACATTGCAAATATTAAATTTACTGAAGTTGCTGTTGGGAATGTTGATGGAATGAAGGCTTCTGACGTAAAAACAGATATTACTTTTGGTAATATCTATGATCCCAATGGCACATTTCAGGCTTATGCAACATTGCCTAATACCTATGCTTATGGAAAAGATCTTTCTGGCCAAGCATGGTTTAGTGATTATCATTATGCAGGTAATACTACACCAGAATTGGGTAATTATGGTCGTTTAACTATTATCCATGAAATTGGTCATACACTGGGTCTTATGCATCCTGGTGATTATAACGCAGGTCAGAATGTTCCAGGTTATTTAAAATCTGATTATGCGGAAGATAGTCGCCAATATACAGTAATGAGCTATTGGGATGAATATGAAACAGGCGCCCACTTCCAAGGTGCTTATGCCGGAGCCCCTCTCCTTCATGATATTTCTGCTATGCAATATCTCTATGGCGCAAATACGACTACCAGAACAGGTGATGATGTATATGGTTTCAATTCAAATACTGGGATTGATTATTATACGGCTACTGATAGCAATGATAAATTAATTTTCTCTGTATGGGATAGTGGTGGTAACGATACATTTGATTTCTCAGGCTTCTATCAAGATCAACTGATTGATTTACGTGCTGGGAACTTTTCTGATGTGGGGGGATTACAGAAAAATGTTTCTATTGCACAAAATGTTACCATAGAAAACGCAATTGGTGGTTTTGGTAATGATATTATTCATGGTAATGATGCTGATAATACTCTTATTGGAGGCGAAGGAGACGATATTATCTATGGCCATAGTGGTAATAACACTATTTATGGTGGTCGTGGACAAGATACATTACATGGTGGCACAGGAAGCAATACCTTTATTTATAAAGAAATTGCAGATTCTTTAGTATCAGCCGCAGATAAAATAATGGATTTCAAAACCGGTATTGATAAAATTGATTTATCAACATTAATTCAAGATACATTTAGTAGCAAAATTCTTAACTTTGTTGATAATTTTACAGGAAATGCTGGCGAAGCAACTCTTAGCTATAATGAAGTAACCAATGCTTCTGAATTAGCCATTAATGCTTATGGCTATAATTATAATCCTGATTTTAAAATTGATATCGTAGGTTTTGTTAATTACGAAACTGATTTTATTGTTTAAGTCATAGTTGGGTAGGAGAAAGTTATTTCTCCTACTCTCTTTTGCTTTAA