Homologs in group_2415

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_19505 FBDBKF_19505 100.0 Morganella morganii S1 metH methionine synthase
EHELCC_16450 EHELCC_16450 100.0 Morganella morganii S2 metH methionine synthase
LHKJJB_16810 LHKJJB_16810 100.0 Morganella morganii S3 metH methionine synthase
HKOGLL_18805 HKOGLL_18805 100.0 Morganella morganii S5 metH methionine synthase
F4V73_RS18620 F4V73_RS18620 91.8 Morganella psychrotolerans metH methionine synthase
PMI_RS13595 PMI_RS13595 77.2 Proteus mirabilis HI4320 metH methionine synthase

Distribution of the homologs in the orthogroup group_2415

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2415

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P13009 0.0 1984 77 3 1228 1 metH Methionine synthase Escherichia coli (strain K12)
P37586 0.0 1978 77 3 1228 3 metH Methionine synthase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q9KUW9 0.0 1837 72 4 1217 3 metH Methionine synthase Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q87L95 0.0 1835 72 5 1218 3 metH Methionine synthase Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Q7MHB1 0.0 1833 72 4 1217 3 metH Methionine synthase Vibrio vulnificus (strain YJ016)
Q8DCJ7 0.0 1833 72 4 1217 3 metH Methionine synthase Vibrio vulnificus (strain CMCP6)
Q9AJQ8 0.0 1820 71 4 1217 3 metH Methionine synthase Aliivibrio fischeri
Q5E814 0.0 1818 71 4 1217 3 metH Methionine synthase Aliivibrio fischeri (strain ATCC 700601 / ES114)
Q9I2Q2 0.0 1655 66 7 1226 3 metH Methionine synthase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q54P92 0.0 1377 53 6 1242 3 mtr Methionine synthase Dictyostelium discoideum
Q4JIJ3 0.0 1324 54 14 1244 2 MTR Methionine synthase Bos taurus
Q9Z2Q4 0.0 1310 53 16 1247 1 Mtr Methionine synthase Rattus norvegicus
Q99707 0.0 1305 53 16 1244 1 MTR Methionine synthase Homo sapiens
A6H5Y3 0.0 1301 53 16 1245 1 Mtr Methionine synthase Mus musculus
Q09582 0.0 1281 52 14 1239 3 metr-1 Probable methionine synthase Caenorhabditis elegans
A8XY95 0.0 1264 52 15 1261 3 metr-1 Probable methionine synthase Caenorhabditis briggsae
O33465 0.0 884 70 0 601 3 metH Methionine synthase (Fragment) Pseudomonas putida
Q57195 0.0 615 52 9 591 3 HI_1042 Uncharacterized protein HI_1042 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q57195 2.96e-08 62 60 0 48 3 HI_1042 Uncharacterized protein HI_1042 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
O33259 4.72e-176 555 31 31 1228 1 metH Methionine synthase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Q49775 5.3e-166 528 30 32 1243 3 metH Methionine synthase Mycobacterium leprae (strain TN)
Q55786 7.24e-164 523 31 35 1238 3 metH Methionine synthase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
O06745 2.85e-32 137 29 12 340 2 yitJ Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase Bacillus subtilis (strain 168)
Q24SP8 7.5e-27 113 37 3 181 3 DSY3155 Corrinoid protein DSY3155 Desulfitobacterium hafniense (strain Y51)
P58979 1.02e-24 107 34 5 216 3 mtbC1 Dimethylamine corrinoid protein 1 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Q8TS74 2.08e-24 106 32 3 178 3 mttC2 Trimethylamine corrinoid protein 2 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Q8TS71 3.15e-24 105 36 3 188 3 mtbC2 Dimethylamine corrinoid protein 2 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Q8TTB0 4.29e-24 105 37 3 186 3 mtbC1 Dimethylamine corrinoid protein 1 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Q8TN69 4.95e-24 105 35 4 208 3 mtbC3 Dimethylamine corrinoid protein 3 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
O93657 1.14e-23 103 36 3 186 1 mtbC Dimethylamine corrinoid protein Methanosarcina barkeri
P58980 4.62e-23 102 35 3 185 3 mtbC2 Dimethylamine corrinoid protein 2 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
P0DX07 7.87e-23 101 33 2 170 1 mtqC Quaternary-amine-specific corrinoid protein Eubacterium limosum
Q8TTA8 2.89e-22 100 32 1 153 3 mttC1 Trimethylamine corrinoid protein 1 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
P58982 3.43e-22 99 31 1 153 3 mttC1 Trimethylamine corrinoid protein 1 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Q46EH4 2.81e-21 98 33 1 174 1 mtaC Methanol--corrinoid protein Methanosarcina barkeri (strain Fusaro / DSM 804)
O93659 5.14e-21 96 30 1 153 1 mttC Trimethylamine corrinoid protein Methanosarcina barkeri
P58868 9.3e-21 95 33 4 188 3 mtmC2 Monomethylamine corrinoid protein 2 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
P58983 2.53e-20 94 29 1 153 3 mttC2 Trimethylamine corrinoid protein 2 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
P58981 4.27e-20 92 37 4 174 3 mtbC3 Dimethylamine corrinoid protein 3 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Q9P9L5 2.23e-18 88 34 3 154 3 mtmC2 Monomethylamine corrinoid protein 2 Methanosarcina barkeri
Q9SDL7 4.65e-18 90 25 9 284 1 HMT-1 Homocysteine S-methyltransferase 1 Arabidopsis thaliana
P58867 4.71e-18 87 35 5 159 3 mtmC1 Monomethylamine corrinoid protein 1 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
O30641 5.12e-18 87 35 4 156 1 mtmC1 Monomethylamine corrinoid protein 1 Methanosarcina barkeri
P58978 8.68e-18 87 33 5 159 3 mtmC2 Monomethylamine corrinoid protein 2 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
A4ZGQ8 9.33e-18 89 25 11 286 1 HMT1 Homocysteine S-methyltransferase 1 Brassica oleracea var. italica
P58977 1.16e-17 86 33 5 159 3 mtmC1 Monomethylamine corrinoid protein 1 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Q9FUN0 7.06e-17 86 25 12 288 2 HMT-1 Homocysteine S-methyltransferase 1 Zea mays
P56707 1.22e-16 86 25 12 332 1 SMTA Selenocysteine methyltransferase Astragalus bisulcatus
Q8LAX0 1.5e-15 83 24 10 338 1 HMT3 Homocysteine S-methyltransferase 3 Arabidopsis thaliana
Q9FUM9 2.3e-15 82 26 13 337 2 HMT-2 Homocysteine S-methyltransferase 2 Zea mays
Q9M1W4 1.87e-14 79 22 10 355 1 HMT-2 Homocysteine S-methyltransferase 2 Arabidopsis thaliana
Q9FUM8 2.05e-14 79 25 11 327 2 HMT-3 Homocysteine S-methyltransferase 3 Zea mays
Q9FUM7 2.52e-13 76 23 10 325 2 HMT-4 Homocysteine S-methyltransferase 4 Zea mays
Q4VNK0 3.27e-13 76 25 11 331 1 SMT Selenocysteine Se-methyltransferase Brassica oleracea var. italica
Q48925 5.59e-13 74 27 2 174 3 mtsB Methylated-thiol--corrinoid protein MtsB Methanosarcina barkeri
Q47690 1.12e-12 73 26 13 326 1 mmuM Homocysteine S-methyltransferase Escherichia coli (strain K12)
O31463 9.67e-12 71 25 16 331 4 ybgG Homocysteine S-methyltransferase YbgG Bacillus subtilis (strain 168)
Q8PUA7 2.23e-11 69 25 2 174 3 mtsB Methylated-thiol--corrinoid protein MtsB Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Q46389 3.4e-10 65 26 10 253 1 acsE 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase Moorella thermoacetica
Q68FT5 1.43e-08 62 25 12 297 2 Bhmt2 S-methylmethionine--homocysteine S-methyltransferase BHMT2 Rattus norvegicus
O09171 1.19e-07 59 22 14 304 1 Bhmt Betaine--homocysteine S-methyltransferase 1 Rattus norvegicus
P0DX08 2.56e-07 57 24 8 246 1 mtqA Methylcorrinoid:tetrahydrofolate methyltransferase Eubacterium limosum
Q93088 3.44e-07 57 22 15 311 1 BHMT Betaine--homocysteine S-methyltransferase 1 Homo sapiens
Q5RFG2 6.07e-07 57 22 15 311 2 BHMT Betaine--homocysteine S-methyltransferase 1 Pongo abelii
Q32LQ4 2.4e-06 55 21 10 290 2 bhmt Betaine--homocysteine S-methyltransferase 1 Danio rerio

  • Number of RefSeq hits:

General

Source Morganella morganii S4
Locus tag NLDBIP_16660
Feature type CDS
Gene metH
Product methionine synthase
Location 4175 - 7855 (strand: 1)
Length 3681 (nucleotides) / 1226 (amino acids)

Contig

Accession ZDB_534
Length 68509 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_2415
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00809 Pterin binding enzyme
PF02310 B12 binding domain
PF02574 Homocysteine S-methyltransferase
PF02607 B12 binding domain
PF02965 Vitamin B12 dependent methionine synthase, activation domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0646 Amino acid transport and metabolism (E) E Methionine synthase I (cobalamin-dependent), methyltransferase domain

Kegg Ortholog Annotation(s)

Protein Sequence

MDNKISVLKKSLNQRILILDGAMGTMIQRYALNEKEYRGERFADWPVDLKGNNDLLSITQPDIIREIHHAYLEAGADIIETNSFNSTVISMADYQMESLSDEINEAAAKLARECADEWTRKTPEKPRYVAGILGPTNRTASISPDVNDPAYRNVSYDALVEAYRSSVRALVRGGADIIMIETIFDTLNAKAAIYAVETEFEALGIKLPVMLSGTITDASGRTLTGQTTEAFYNSMRHIRPISFGLNCALGPAELRQYVAELSRIADCYVSTHPNAGLPNAFGGYDLDAANMAGYISEWAQSGLLNIVGGCCGTTPDHIRAIAQAVADIPPRVIPDRPVACRLAGLEPLTIDENSLFVNVGERTNITGSARFKRLIKEGNYQEALDIARNQVENGAQIIDINMDEGMLDSQAAMVRFLNMISGEPDIARVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEAAFIDHAKKVLRYGAAVIVMAFDETGQADTRQRKTEICQRAYRILTERVGFPPEDIIFDPNIFAVATGIPEHNNYAVDFIEACKDIKATLPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAALRDAVEDVILNRREDGTDRLLALAEEYRGSKGENDQPQLAEWRGWDVEKRLEYALVKGVTEFIVEDTEAARLRADSPIEVIEGPLMNGMNVVGDLFSEGKMFLPQVVKSARVMKQAVAYLEPYIQAAKTSGSSAGKVLLATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVPCETILRTAIEEKVDIIGLSGLITPSLDEMVHVAKEMERQGFSLPLLIGGATTSKAHTAVKIEPNYSGPVTYVQNASRTVGVVAALLSDKQRDEFVARTRKEYEVVRDQYARRQPRSAPVTLAQARANAFAADWDNYTPPRPAFTGVKTVTAPISVLRRYIDWTPFFMTWSLAGKYPRILEDDVVGEEARRLFKEANAMLDELDRTGALTPRGVAGIFPANRIGDDIAVYRDESREEVLLYSCHLRQQTQKKDDFPNACLADFVAPPGIPDYLGAFAVTGGLEEDTLAAQFDAAHDDYNKIMVKALADRLAEGFAEYLHEQVRKTIWGYSPDENLDNDSLIRENYQGIRPAPGYPACPEHTEKSKIWELLDVERHTGMRLTESYAMWPGASVSGWYFSHPQSRYFAVAQIQRDQIEDYAARKGMPVKELERWLAPNLGYDPED

Flanking regions ( +/- flanking 50bp)

AGACGTTCAGACGGCTATTTAAACGGGCATTGCAGAGCGGAGTCAGATAAATGGATAATAAAATCAGTGTATTAAAAAAATCGCTTAATCAACGGATCCTGATTCTTGATGGTGCGATGGGAACAATGATCCAGCGCTATGCACTGAACGAAAAGGAATACCGCGGTGAGCGTTTTGCTGACTGGCCGGTGGATCTGAAAGGAAATAACGATCTGTTATCCATTACGCAGCCGGATATTATCCGTGAAATTCATCACGCCTATCTGGAAGCCGGTGCGGATATTATTGAAACCAACAGCTTTAACTCCACGGTTATTTCCATGGCGGATTATCAGATGGAGTCCCTGTCTGATGAAATCAATGAAGCTGCCGCGAAACTGGCGCGGGAATGTGCCGATGAATGGACGCGCAAAACGCCGGAGAAACCCCGCTATGTGGCCGGGATTCTGGGGCCGACCAACCGGACGGCGTCAATCTCCCCCGATGTGAATGATCCGGCTTACCGCAATGTATCCTATGATGCGCTGGTTGAGGCATACCGCAGCTCTGTGCGGGCACTGGTCCGCGGCGGGGCTGATATCATTATGATCGAAACAATCTTCGATACCCTGAATGCCAAGGCGGCGATTTACGCTGTTGAAACCGAGTTTGAGGCGCTGGGGATTAAATTGCCGGTGATGCTTTCCGGTACGATCACTGATGCCTCCGGCCGGACACTGACCGGTCAGACAACTGAAGCCTTTTATAACTCTATGCGCCACATCCGTCCGATCTCTTTCGGGCTTAACTGTGCGCTGGGGCCTGCTGAACTGCGCCAGTATGTGGCCGAACTGTCCCGTATCGCGGATTGTTATGTCAGTACTCACCCGAATGCCGGTCTGCCGAATGCGTTCGGCGGTTATGACCTGGATGCCGCCAATATGGCGGGCTATATCAGTGAGTGGGCGCAGTCCGGTTTGCTGAATATTGTCGGTGGCTGCTGCGGCACCACGCCCGATCATATCCGTGCAATTGCACAGGCGGTGGCGGATATTCCGCCGCGTGTTATTCCTGATCGTCCTGTGGCCTGCCGTCTGGCGGGACTGGAGCCGCTGACCATCGATGAAAATTCCCTGTTCGTCAACGTGGGGGAGAGAACCAATATCACCGGCTCCGCACGGTTTAAGCGGCTGATTAAAGAAGGTAATTACCAGGAAGCATTGGATATTGCCCGTAACCAGGTGGAGAACGGCGCACAGATTATTGATATCAACATGGATGAGGGCATGCTGGATTCACAGGCTGCCATGGTGCGTTTCCTGAATATGATTTCCGGTGAGCCGGATATTGCCCGCGTACCGATTATGATCGACTCCTCAAAATGGGAGGTGATCGAGGCCGGGCTGAAATGTATCCAGGGTAAAGGCATTGTGAACTCGATTTCCCTGAAAGAGGGAGAGGCAGCCTTTATCGATCATGCCAAAAAAGTGCTGCGTTACGGTGCTGCCGTGATTGTGATGGCCTTTGATGAAACCGGCCAGGCGGATACCCGGCAGCGCAAGACAGAAATCTGTCAGCGGGCTTACCGCATTCTGACTGAGCGGGTGGGATTTCCGCCGGAAGATATTATTTTTGACCCGAATATTTTTGCGGTGGCAACCGGTATTCCTGAGCATAACAATTATGCCGTTGATTTTATTGAAGCCTGTAAGGATATCAAAGCAACACTGCCCCATGCACTGATCTCCGGCGGGGTCTCCAACGTCTCTTTCTCGTTCCGCGGAAATGATCCGGTACGGGAAGCGATTCACGCCGTTTTCCTCTATTACGCTATCCGTAACGGCATGGACATGGGGATTGTGAATGCCGGGCAACTGGCCATTTATGATGATTTGCCGGCTGCACTGCGTGATGCGGTGGAAGATGTGATCCTGAACCGCCGCGAGGATGGTACAGACCGGCTGCTGGCGCTGGCAGAAGAATATCGCGGCAGCAAAGGGGAAAATGATCAGCCGCAGCTTGCGGAATGGCGCGGGTGGGATGTGGAAAAGCGTCTGGAATATGCGCTGGTGAAAGGGGTCACCGAATTTATTGTTGAGGATACCGAAGCTGCCCGTCTGCGTGCTGACAGCCCGATTGAAGTGATCGAAGGTCCGCTGATGAACGGCATGAATGTGGTCGGTGATCTGTTCAGTGAGGGAAAAATGTTTCTGCCGCAGGTGGTGAAATCCGCGCGGGTGATGAAACAGGCGGTGGCGTATCTGGAACCTTATATTCAGGCAGCGAAAACCAGCGGCTCCAGTGCCGGGAAAGTCCTGCTGGCGACAGTCAAAGGCGATGTGCATGATATCGGCAAGAATATCGTCGGCGTGGTATTGCAGTGTAATAACTATGAAATTATCGATCTCGGGGTGATGGTGCCCTGTGAAACAATTCTCCGCACGGCTATTGAGGAAAAAGTCGATATTATCGGGCTGTCCGGGCTTATCACGCCGTCACTGGATGAAATGGTACATGTAGCCAAAGAGATGGAGCGTCAGGGATTTTCCCTGCCGCTGCTGATCGGCGGTGCCACCACATCCAAAGCTCATACGGCGGTGAAAATTGAACCGAATTACAGCGGCCCGGTAACCTATGTACAGAATGCCTCACGGACGGTCGGGGTCGTGGCGGCGTTATTGTCAGATAAACAACGGGATGAATTTGTTGCCCGCACCCGTAAAGAATATGAGGTTGTCCGCGACCAGTATGCCCGCCGTCAGCCGCGCTCAGCACCGGTGACACTCGCACAGGCGCGGGCAAATGCGTTTGCGGCGGACTGGGATAATTATACGCCGCCGCGCCCGGCATTTACCGGCGTGAAAACCGTCACTGCACCGATTTCGGTACTGCGCCGTTATATTGACTGGACACCTTTCTTTATGACCTGGTCGCTGGCCGGAAAATACCCGCGTATTCTGGAAGATGATGTCGTTGGTGAAGAAGCCCGCCGCCTGTTTAAAGAGGCAAACGCGATGCTGGATGAGCTGGACAGAACCGGCGCACTGACACCGCGTGGCGTGGCGGGGATCTTCCCGGCTAACCGGATCGGCGATGATATCGCGGTTTACCGTGACGAATCCCGCGAAGAGGTGCTGTTATACAGTTGTCATCTGCGCCAGCAGACACAGAAGAAAGATGATTTCCCGAATGCCTGCCTGGCGGATTTTGTCGCGCCACCGGGGATTCCGGATTACCTCGGAGCTTTTGCCGTCACCGGCGGGCTGGAGGAGGATACACTGGCAGCTCAGTTTGATGCGGCACACGATGATTACAATAAAATCATGGTGAAAGCCCTTGCTGACCGGCTGGCGGAAGGATTTGCGGAGTATCTGCATGAGCAGGTGCGTAAAACCATCTGGGGCTACAGTCCGGATGAAAACCTGGATAATGACTCGCTGATCCGTGAAAACTATCAGGGGATCCGCCCTGCACCCGGCTATCCGGCCTGCCCGGAACATACGGAGAAAAGCAAAATCTGGGAACTGCTGGATGTTGAAAGACATACCGGCATGCGGCTGACGGAATCTTATGCTATGTGGCCGGGGGCATCGGTATCCGGCTGGTATTTCAGTCATCCGCAGAGCCGCTATTTTGCGGTGGCTCAGATCCAGAGAGATCAGATTGAGGATTATGCCGCCCGCAAAGGTATGCCGGTGAAAGAGCTTGAGCGCTGGCTGGCCCCGAACCTGGGGTATGATCCGGAAGACTGAGTATTATCGCATGTCAGTCTCCTGTCCCGGTTTGCGTTAACCACCGGGTA