Homologs in group_918

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_04965 FBDBKF_04965 100.0 Morganella morganii S1 purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
EHELCC_06255 EHELCC_06255 100.0 Morganella morganii S2 purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
NLDBIP_06575 NLDBIP_06575 100.0 Morganella morganii S4 purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
HKOGLL_06930 HKOGLL_06930 100.0 Morganella morganii S5 purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
F4V73_RS16105 F4V73_RS16105 90.2 Morganella psychrotolerans purE 5-(carboxyamino)imidazole ribonucleotide mutase
PMI_RS10650 PMI_RS10650 80.1 Proteus mirabilis HI4320 purE 5-(carboxyamino)imidazole ribonucleotide mutase

Distribution of the homologs in the orthogroup group_918

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_918

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0AG18 6.71e-78 232 79 1 168 1 purE N5-carboxyaminoimidazole ribonucleotide mutase Escherichia coli (strain K12)
P0AG19 6.71e-78 232 79 1 168 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Escherichia coli O157:H7
P43849 1.18e-76 229 75 0 162 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q87KE1 5.77e-69 209 66 0 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
P72157 1.91e-67 205 64 0 162 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q5E1R4 2.71e-66 202 65 0 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Aliivibrio fischeri (strain ATCC 700601 / ES114)
P12044 1.28e-65 201 64 0 155 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Bacillus subtilis (strain 168)
Q7MGL2 6.46e-63 194 67 0 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Vibrio vulnificus (strain YJ016)
Q8DDD7 6.46e-63 194 67 0 159 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Vibrio vulnificus (strain CMCP6)
Q9KVT7 2.89e-60 187 65 0 158 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q8FYW3 2.11e-59 185 68 0 154 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Brucella suis biovar 1 (strain 1330)
P52558 3.53e-59 184 68 0 154 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Brucella melitensis biotype 1 (strain ATCC 23456 / CCUG 17765 / NCTC 10094 / 16M)
Q54QE4 6.27e-51 178 62 0 154 1 purC/E Bifunctional purine synthesis protein purC/E Dictyostelium discoideum
O06456 4.45e-50 161 52 1 153 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Q9UY68 7.46e-50 161 53 1 151 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Pyrococcus abyssi (strain GE5 / Orsay)
Q9WYS7 1.34e-48 158 49 1 153 1 purE N5-carboxyaminoimidazole ribonucleotide mutase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
O67239 3.59e-48 157 50 1 150 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Aquifex aeolicus (strain VF5)
P15567 8.28e-47 163 53 1 158 3 ade6 Phosphoribosylaminoimidazole carboxylase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
O58058 1.43e-46 153 56 1 131 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Q44679 6.32e-45 149 51 1 148 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Corynebacterium ammoniagenes
Q55498 1.97e-44 147 55 1 156 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
P55195 2.88e-44 156 47 1 160 2 PURKE Phosphoribosylaminoimidazole carboxylase, chloroplastic (Fragment) Vigna aconitifolia
P46702 4.22e-44 146 52 1 151 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Mycobacterium leprae (strain TN)
P9WHM1 1.3e-43 145 52 1 151 1 purE N5-carboxyaminoimidazole ribonucleotide mutase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WHM0 1.3e-43 145 52 1 151 3 purE N5-carboxyaminoimidazole ribonucleotide mutase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
O74197 6.15e-42 150 49 1 151 1 ADE2 Phosphoribosylaminoimidazole carboxylase Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
P50504 7.09e-42 150 50 1 158 3 ADE2 Phosphoribosylaminoimidazole carboxylase Schwanniomyces occidentalis
P21264 1.01e-41 149 49 1 151 1 ADE2 Phosphoribosylaminoimidazole carboxylase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q92210 7.72e-40 144 47 2 168 3 ADE2 Phosphoribosylaminoimidazole carboxylase Candida albicans (strain SC5314 / ATCC MYA-2876)
Q01930 2.58e-38 140 55 1 132 3 ADE1 Phosphoribosylaminoimidazole carboxylase Ogataea methanolica
P0CQ36 9.17e-35 130 50 1 155 3 ADE2 Phosphoribosylaminoimidazole carboxylase Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
P0CQ37 1.26e-34 130 50 1 155 3 ADE2 Phosphoribosylaminoimidazole carboxylase Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
P0C017 1.8e-34 130 49 1 159 2 ADE2 Phosphoribosylaminoimidazole carboxylase Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
Q58033 1.18e-32 117 46 3 150 1 purE N5-carboxyaminoimidazole ribonucleotide mutase Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
P22348 2.62e-30 115 42 2 154 3 purE Probable N5-carboxyaminoimidazole ribonucleotide mutase Methanobrevibacter smithii
P22348 7.53e-13 68 30 3 134 3 purE Probable N5-carboxyaminoimidazole ribonucleotide mutase Methanobrevibacter smithii
P41654 1.49e-28 110 41 2 151 3 purE Probable N5-carboxyaminoimidazole ribonucleotide mutase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
P41654 2.53e-09 58 31 4 154 3 purE Probable N5-carboxyaminoimidazole ribonucleotide mutase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
O28997 5.24e-13 67 30 5 159 3 purE Phosphoribosylaminoimidazole carboxylase Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
Q73PV9 1.17e-07 52 28 4 154 1 purE Phosphoribosylaminoimidazole carboxylase Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
P51583 1.89e-07 53 27 4 142 1 Paics Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Rattus norvegicus
P38024 9.61e-07 51 27 4 142 2 AIRC Multifunctional protein ADE2 Gallus gallus
Q9DCL9 1.08e-06 50 26 4 142 1 Paics Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Mus musculus
P22234 1.4e-06 50 26 4 142 1 PAICS Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Homo sapiens
Q5RB59 2.3e-06 50 26 4 142 2 PAICS Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Pongo abelii

  • Number of RefSeq hits:

General

Source Morganella morganii S3
Locus tag LHKJJB_03455
Feature type CDS
Gene purE
Product Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
Location 276391 - 276915 (strand: 1)
Length 525 (nucleotides) / 174 (amino acids)

Contig

Accession ZDB_360
Length 302856 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_918
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00731 AIR carboxylase

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0041 Nucleotide transport and metabolism (F) F Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01588 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] Purine metabolism
Metabolic pathways
Biosynthesis of secondary metabolites		 De novo purine biosynthesis, PRPP + glutamine => IMP

Protein Sequence

MNAASSQQHSPAAKVAIVMGSKSDWSTMEHAAAILDMLQVPYHTEVVSAHRTPDKLFSFAETAKQNGFDVIIAGAGGAAHLPGMLAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPKGIPVGTLAIGKAGAANAALLAAQILALHDEALLIRLTDWRNAQTDDVLSHPDPREAN

Flanking regions ( +/- flanking 50bp)

CGGACGTCTGTCAATTTTCGTGACGCGGGATGTACAGGAGCACCGAAAACATGAACGCCGCCTCTTCGCAACAACACTCACCGGCAGCCAAAGTGGCTATTGTTATGGGATCCAAAAGTGACTGGAGCACCATGGAACACGCCGCAGCGATCCTCGATATGCTTCAGGTGCCTTATCACACAGAAGTGGTTTCCGCGCACCGCACGCCGGACAAACTGTTTTCCTTTGCTGAAACCGCAAAACAGAACGGGTTTGATGTGATCATTGCCGGTGCCGGTGGTGCCGCGCATCTGCCGGGGATGCTGGCGGCGAAAACCCTCGTTCCGGTACTGGGTGTGCCGGTGCAGAGTGCCGCGCTCAGCGGTGTCGACAGTCTCTATTCCATTGTGCAGATGCCGAAAGGCATTCCGGTCGGTACGCTGGCTATCGGCAAAGCCGGTGCCGCCAATGCCGCCCTGCTCGCCGCACAGATCCTCGCCCTGCATGATGAGGCGCTGCTTATCCGCCTGACAGACTGGCGCAATGCGCAGACCGATGATGTCCTCAGCCACCCGGATCCGCGGGAGGCCAACTGATGAAACCGGTGTGTGTTCTGGGAAACGGCCAACTGGGCCGGATGCTGCGC