Homologs in group_830

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_04175 FBDBKF_04175 100.0 Morganella morganii S1 - 5-formyltetrahydrofolate cyclo-ligase
EHELCC_05465 EHELCC_05465 100.0 Morganella morganii S2 - 5-formyltetrahydrofolate cyclo-ligase
NLDBIP_05785 NLDBIP_05785 100.0 Morganella morganii S4 - 5-formyltetrahydrofolate cyclo-ligase
LHKJJB_02665 LHKJJB_02665 100.0 Morganella morganii S3 - 5-formyltetrahydrofolate cyclo-ligase
F4V73_RS08620 F4V73_RS08620 84.6 Morganella psychrotolerans - 5-formyltetrahydrofolate cyclo-ligase
PMI_RS09995 PMI_RS09995 59.7 Proteus mirabilis HI4320 - 5-formyltetrahydrofolate cyclo-ligase

Distribution of the homologs in the orthogroup group_830

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_830

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0AC28 2.32e-73 222 56 0 182 1 ygfA 5-formyltetrahydrofolate cyclo-ligase Escherichia coli (strain K12)
P0AC29 2.32e-73 222 56 0 182 3 ygfA 5-formyltetrahydrofolate cyclo-ligase Escherichia coli O157:H7
P44905 1.09e-71 218 56 0 183 1 HI_0858 5-formyltetrahydrofolate cyclo-ligase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q89AD6 1.84e-58 185 45 1 193 3 bbp_370 Uncharacterized protein bbp_370 Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Q8K9E3 4.28e-49 161 39 0 186 3 BUsg_396 Uncharacterized protein BUsg_396 Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
P54491 1.22e-25 100 31 2 184 1 yqgN Uncharacterized protein YqgN Bacillus subtilis (strain 168)
P80405 2.23e-19 85 29 4 188 1 MTHFS 5-formyltetrahydrofolate cyclo-ligase Oryctolagus cuniculus
P49914 3.92e-18 81 28 4 196 1 MTHFS 5-formyltetrahydrofolate cyclo-ligase Homo sapiens
Q9D110 1.87e-17 80 29 5 188 2 Mthfs 5-formyltetrahydrofolate cyclo-ligase Mus musculus
Q9P7W2 1.36e-16 77 24 6 197 3 SPBC1703.08c Probable 5-formyltetrahydrofolate cyclo-ligase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A0R3H2 1.33e-11 63 27 5 189 1 MSMEG_5472 5-formyltetrahydrofolate cyclo-ligase Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
Q9XWE6 6.52e-10 59 25 4 196 3 Y106G6E.4 Probable 5-formyltetrahydrofolate cyclo-ligase Caenorhabditis elegans
P47487 3e-09 57 27 7 188 3 MG245 5-formyltetrahydrofolate cyclo-ligase Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
P75430 7.11e-07 50 28 7 184 1 MPN_348 5-formyltetrahydrofolate cyclo-ligase Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)
P40099 2.77e-05 46 27 9 173 1 FAU1 5-formyltetrahydrofolate cyclo-ligase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q8L539 0.000241 44 27 11 213 1 5FCL 5-formyltetrahydrofolate cyclo-ligase, mitochondrial Arabidopsis thaliana

  • Number of RefSeq hits:

General

Source Morganella morganii S5
Locus tag HKOGLL_06140
Feature type CDS
Gene -
Product 5-formyltetrahydrofolate cyclo-ligase
Location 20167 - 20772 (strand: 1)
Length 606 (nucleotides) / 201 (amino acids)

Contig

Accession ZDB_683
Length 224720 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_830
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF01812 5-formyltetrahydrofolate cyclo-ligase family

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0212 Coenzyme transport and metabolism (H) H 5-formyltetrahydrofolate cyclo-ligase

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01934 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] One carbon pool by folate
Metabolic pathways		 -

Protein Sequence

MTHDPLLQARHHLRQLIRNKRRALTPQQQSTAAQDLVQQIIHHPDIHRANNIALFLSFDGEIDTRPLTEWLWSQGKQVFLPVLHPFSRHHLLFLAYRPDTPLIKNKFSISEPALDVTQVLPPQELDIMFIPLVAFDEKGERLGMGGGFYDRTLAGWQKKGFYPVGLAHDCQQVDELPAAQWDVPLPEVITPSRRWLWPEHN

Flanking regions ( +/- flanking 50bp)

TCTTGGAGACCTCTCTCTTCTTTATCTCCTGATATTTCGCTGATTTCACTATGACTCATGACCCGTTGTTACAAGCGCGGCATCATCTGCGTCAGTTAATCCGCAATAAGCGCCGTGCGCTGACACCTCAGCAGCAAAGCACTGCCGCACAAGACCTTGTTCAGCAAATCATTCATCACCCTGATATACACCGCGCCAATAATATTGCCCTGTTTCTCTCTTTTGATGGTGAGATTGATACCCGTCCGCTGACAGAGTGGCTGTGGTCACAGGGAAAACAGGTATTTTTACCTGTTCTTCACCCGTTCAGCCGCCATCATCTGTTATTCCTTGCTTATCGCCCTGATACCCCGCTGATTAAAAACAAATTTTCAATTTCAGAACCGGCATTGGATGTCACACAGGTATTACCGCCTCAGGAACTGGATATTATGTTTATTCCGCTGGTCGCGTTTGATGAAAAAGGAGAGCGTCTCGGGATGGGCGGCGGTTTTTATGACCGCACACTGGCGGGCTGGCAGAAGAAAGGGTTTTACCCGGTAGGGCTGGCACATGATTGTCAGCAGGTTGATGAACTTCCTGCCGCACAGTGGGATGTCCCGCTGCCGGAAGTGATCACGCCATCACGTCGCTGGCTGTGGCCGGAACACAACTAAACTTGAATAAACATACGGTTAATTAACAGAAAGATACACCATTCACACAT