Homologs in group_2364

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_19070 FBDBKF_19070 100.0 Morganella morganii S1 - Uncharacterized C-terminal domain of topoisomerase IA
NLDBIP_18830 NLDBIP_18830 100.0 Morganella morganii S4 - Uncharacterized C-terminal domain of topoisomerase IA
LHKJJB_18685 LHKJJB_18685 100.0 Morganella morganii S3 - Uncharacterized C-terminal domain of topoisomerase IA
HKOGLL_18420 HKOGLL_18420 100.0 Morganella morganii S5 - Uncharacterized C-terminal domain of topoisomerase IA
F4V73_RS19095 F4V73_RS19095 87.8 Morganella psychrotolerans - topoisomerase DNA-binding C4 zinc finger domain-containing protein
PMI_RS16320 PMI_RS16320 66.3 Proteus mirabilis HI4320 - type I DNA topoisomerase

Distribution of the homologs in the orthogroup group_2364

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_2364

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P45771 5.19e-82 243 65 0 163 4 yrdD Uncharacterized protein YrdD Escherichia coli (strain K12)
P46494 6.69e-46 151 45 3 162 4 HI_0656.1 Uncharacterized protein HI_0656.1 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P46494 3.53e-14 70 35 5 125 4 HI_0656.1 Uncharacterized protein HI_0656.1 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P55991 2.02e-27 111 38 6 147 1 topA DNA topoisomerase 1 Helicobacter pylori (strain ATCC 700392 / 26695)
P55991 9.28e-15 74 38 4 114 1 topA DNA topoisomerase 1 Helicobacter pylori (strain ATCC 700392 / 26695)
Q9KA23 2.27e-26 108 43 2 110 3 topA DNA topoisomerase 1 Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Q9KA23 2.2e-11 65 32 7 111 3 topA DNA topoisomerase 1 Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Q9ZMV7 2.87e-26 107 39 6 145 3 topA DNA topoisomerase 1 Helicobacter pylori (strain J99 / ATCC 700824)
Q9ZMV7 1.59e-14 73 38 4 114 3 topA DNA topoisomerase 1 Helicobacter pylori (strain J99 / ATCC 700824)
Q9CG80 9.29e-25 103 35 1 117 3 topA DNA topoisomerase 1 Lactococcus lactis subsp. lactis (strain IL1403)
Q9CG80 1.69e-07 53 33 8 117 3 topA DNA topoisomerase 1 Lactococcus lactis subsp. lactis (strain IL1403)
P39814 4.19e-24 101 37 3 120 1 topA DNA topoisomerase 1 Bacillus subtilis (strain 168)
P39814 2.42e-11 64 35 7 109 1 topA DNA topoisomerase 1 Bacillus subtilis (strain 168)
Q59046 6.68e-24 100 35 6 154 3 topA DNA topoisomerase 1 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q59046 2.97e-07 52 58 0 34 3 topA DNA topoisomerase 1 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q49X35 1.87e-23 99 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)
Q49X35 1.48e-10 62 33 7 115 3 topA DNA topoisomerase 1 Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)
Q9PLZ2 7.04e-23 98 35 3 133 3 topA DNA topoisomerase 1 Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Q9PLZ2 2.64e-14 73 33 4 126 3 topA DNA topoisomerase 1 Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Q2YXL8 1.87e-22 97 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain bovine RF122 / ET3-1)
Q2YXL8 5.39e-11 63 33 8 127 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain bovine RF122 / ET3-1)
Q8CSU3 1.93e-22 96 37 2 110 3 topA DNA topoisomerase 1 Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
Q8CSU3 1.74e-12 68 35 7 115 3 topA DNA topoisomerase 1 Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
Q5HPU2 1.93e-22 96 37 2 110 3 topA DNA topoisomerase 1 Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
Q5HPU2 1.74e-12 68 35 7 115 3 topA DNA topoisomerase 1 Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
Q06AK7 1.99e-22 96 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus aureus
Q06AK7 5.76e-11 63 33 8 127 3 topA DNA topoisomerase 1 Staphylococcus aureus
Q8NWZ9 2.25e-22 96 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain MW2)
Q8NWZ9 6.46e-11 63 33 8 127 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain MW2)
Q6G9W3 2.25e-22 96 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain MSSA476)
Q6G9W3 6.46e-11 63 33 8 127 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain MSSA476)
Q6GHI5 2.25e-22 96 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain MRSA252)
Q6GHI5 6.46e-11 63 33 8 127 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain MRSA252)
Q7A5Y5 2.25e-22 96 35 3 120 1 topA DNA topoisomerase 1 Staphylococcus aureus (strain N315)
Q7A5Y5 6.46e-11 63 33 8 127 1 topA DNA topoisomerase 1 Staphylococcus aureus (strain N315)
Q99UM1 2.25e-22 96 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain Mu50 / ATCC 700699)
Q99UM1 6.46e-11 63 33 8 127 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain Mu50 / ATCC 700699)
Q5HGI2 2.32e-22 96 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain COL)
Q5HGI2 7.04e-11 63 33 8 127 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain COL)
Q2FZ32 2.32e-22 96 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain NCTC 8325 / PS 47)
Q2FZ32 7.04e-11 63 33 8 127 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain NCTC 8325 / PS 47)
Q2FHI8 2.32e-22 96 35 3 120 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain USA300)
Q2FHI8 7.04e-11 63 33 8 127 3 topA DNA topoisomerase 1 Staphylococcus aureus (strain USA300)
Q4L5V2 8.93e-22 94 39 1 99 3 topA DNA topoisomerase 1 Staphylococcus haemolyticus (strain JCSC1435)
Q4L5V2 5.48e-13 69 36 7 115 3 topA DNA topoisomerase 1 Staphylococcus haemolyticus (strain JCSC1435)
O83409 5e-17 81 34 1 111 3 topA DNA topoisomerase 1 Treponema pallidum (strain Nichols)
O83409 4.39e-08 55 28 6 125 3 topA DNA topoisomerase 1 Treponema pallidum (strain Nichols)
Q9JN65 7.26e-14 72 36 3 96 3 topA DNA topoisomerase 1 Mycoplasmoides gallisepticum (strain R(low / passage 15 / clone 2))
Q9JN65 7.4e-14 72 32 3 101 3 topA DNA topoisomerase 1 Mycoplasmoides gallisepticum (strain R(low / passage 15 / clone 2))
P47368 2.64e-10 61 38 4 84 3 topA DNA topoisomerase 1 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
P47368 8.68e-10 60 34 4 82 3 topA DNA topoisomerase 1 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
P78032 6.65e-10 60 35 4 84 3 topA DNA topoisomerase 1 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)
P78032 2.41e-09 58 34 5 85 3 topA DNA topoisomerase 1 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)
O27661 1.46e-09 59 33 4 117 3 topA DNA topoisomerase 1 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Q9HM08 3.82e-09 58 31 8 132 3 topA DNA topoisomerase 1 Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Q9HM08 7.73e-07 51 40 6 81 3 topA DNA topoisomerase 1 Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
O28469 2.08e-07 53 34 4 81 3 topA DNA topoisomerase 1 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
O28469 2.27e-06 50 58 1 34 3 topA DNA topoisomerase 1 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
Q9PHK2 1.09e-05 48 36 3 79 3 XF_a0003 DNA topoisomerase I, plasmid Xylella fastidiosa (strain 9a5c)
Q9X3X7 1.15e-05 48 50 2 42 3 topA DNA topoisomerase 1 Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Q9X3X7 6.23e-05 46 47 1 40 3 topA DNA topoisomerase 1 Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Q1RIM1 2.52e-05 47 37 1 53 3 topA DNA topoisomerase 1 Rickettsia bellii (strain RML369-C)
Q1RIM1 0.000324 43 32 4 86 3 topA DNA topoisomerase 1 Rickettsia bellii (strain RML369-C)
P06612 6.78e-05 45 27 8 140 1 topA DNA topoisomerase 1 Escherichia coli (strain K12)
Q92IH1 0.000145 45 39 1 43 3 topA DNA topoisomerase 1 Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Q92IH1 0.000565 43 38 1 44 3 topA DNA topoisomerase 1 Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Q68X45 0.000151 45 28 5 102 3 topA DNA topoisomerase 1 Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Q68X45 0.000206 44 33 2 62 3 topA DNA topoisomerase 1 Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Q9ZDK2 0.000196 44 32 4 83 3 topA DNA topoisomerase 1 Rickettsia prowazekii (strain Madrid E)
Q9ZDK2 0.000224 44 39 1 43 3 topA DNA topoisomerase 1 Rickettsia prowazekii (strain Madrid E)
Q9CN30 0.000203 44 26 8 153 3 topA DNA topoisomerase 1 Pasteurella multocida (strain Pm70)
Q4UM42 0.000293 44 30 3 86 3 topA DNA topoisomerase 1 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Q4UM42 0.000549 43 39 1 43 3 topA DNA topoisomerase 1 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Q9HZJ5 0.000636 43 31 2 79 3 topA DNA topoisomerase 1 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P43012 0.000654 43 24 10 198 3 topA DNA topoisomerase 1 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

  • Number of RefSeq hits:

General

Source Morganella morganii S2
Locus tag EHELCC_18815
Feature type CDS
Gene -
Product Uncharacterized C-terminal domain of topoisomerase IA
Location 2577 - 3122 (strand: -1)
Length 546 (nucleotides) / 181 (amino acids)

Contig

Accession ZDB_240
Length 24827 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_2364
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF01396 Topoisomerase DNA binding C4 zinc finger

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0551 Replication, recombination and repair (L) L DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K07479 putative DNA topoisomerase - -

Protein Sequence

MSKSMAECCPECGGELVIRNGAHGPFFGCSAYPECDYIRPLKAGTDGHIIKVLDGQLCPQCGGTLVLRQGRYGMFIGCGNFPECEYIASIDSPDETTVACPQCHDGKLLQRKSRFGKVFYACNRYPACQFSLNSKPVAGECQYCGYPLLVEKRTSTGVRLSCASKACAKRQKEQNENNDES

Flanking regions ( +/- flanking 50bp)

GATACATCCGCCTGCATCACTGAACGGTATCGGCGTAAGGTAAAATTATCATGTCAAAATCAATGGCGGAATGCTGTCCGGAATGCGGCGGAGAGCTGGTTATCCGTAATGGTGCCCACGGGCCTTTTTTCGGCTGTTCTGCTTATCCGGAATGTGATTACATCCGTCCACTGAAAGCCGGTACTGACGGGCATATCATCAAAGTGCTGGACGGACAGTTGTGCCCGCAGTGCGGCGGGACGCTGGTGCTGCGCCAGGGGCGCTACGGGATGTTTATCGGCTGCGGAAATTTTCCGGAATGTGAATATATTGCATCTATTGATTCACCAGATGAAACGACGGTGGCCTGTCCGCAGTGCCATGATGGTAAGTTACTTCAGCGTAAGTCACGGTTCGGTAAAGTTTTTTATGCCTGTAACCGCTATCCTGCCTGCCAGTTTTCACTGAACAGCAAACCGGTTGCCGGTGAGTGTCAGTATTGTGGTTATCCGCTGCTGGTGGAAAAAAGGACATCAACAGGCGTAAGATTAAGTTGTGCGAGTAAAGCCTGCGCAAAACGACAAAAAGAACAAAATGAGAATAATGATGAATCATAATCAAACCACAGCAAATTTCGACACAATTATAAAAGCCCTGAATAACCACG