Homologs in group_92

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11 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_09245 FBDBKF_09245 46.6 Morganella morganii S1 metC Cystathionine beta-lyase/cystathionine gamma-synthase
FBDBKF_10625 FBDBKF_10625 100.0 Morganella morganii S1 megL methionine gamma-lyase
EHELCC_10165 EHELCC_10165 46.6 Morganella morganii S2 metC Cystathionine beta-lyase/cystathionine gamma-synthase
NLDBIP_10510 NLDBIP_10510 46.6 Morganella morganii S4 metC Cystathionine beta-lyase/cystathionine gamma-synthase
NLDBIP_14790 NLDBIP_14790 100.0 Morganella morganii S4 megL methionine gamma-lyase
LHKJJB_10845 LHKJJB_10845 46.6 Morganella morganii S3 metC Cystathionine beta-lyase/cystathionine gamma-synthase
LHKJJB_14555 LHKJJB_14555 100.0 Morganella morganii S3 megL methionine gamma-lyase
HKOGLL_13175 HKOGLL_13175 100.0 Morganella morganii S5 megL methionine gamma-lyase
HKOGLL_13905 HKOGLL_13905 46.6 Morganella morganii S5 metC Cystathionine beta-lyase/cystathionine gamma-synthase
F4V73_RS10725 F4V73_RS10725 45.6 Morganella psychrotolerans - PLP-dependent aspartate aminotransferase family protein
F4V73_RS14335 F4V73_RS14335 95.0 Morganella psychrotolerans megL methionine gamma-lyase

Distribution of the homologs in the orthogroup group_92

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_92

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q8L0X4 2.63e-177 502 60 2 389 1 mgl L-methionine gamma-lyase Fusobacterium nucleatum subsp. polymorphum
Q73KL7 3.54e-175 497 58 2 392 1 megL L-methionine gamma-lyase Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
Q8RDT4 4.18e-173 491 59 2 389 1 FN1419 L-methionine gamma-lyase Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
Q7MX71 8.69e-173 491 59 2 392 1 mgl L-methionine gamma-lyase Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
P13254 9.25e-143 414 50 1 391 1 mdeA L-methionine gamma-lyase Pseudomonas putida
A0A0J6G7P5 1.81e-140 409 51 3 400 3 megL L-methionine gamma-lyase Pseudomonas deceptionensis
Q83A83 1.89e-125 370 47 3 385 1 metC Cystathionine beta-lyase Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Q55DV9 8.17e-122 361 47 4 386 1 cysA Cystathionine gamma-lyase Dictyostelium discoideum
O05394 1.73e-120 357 48 4 383 1 mccB Cystathionine gamma-lyase Bacillus subtilis (strain 168)
P56069 7.93e-118 350 46 4 385 1 metB Cystathionine gamma-synthase Helicobacter pylori (strain ATCC 700392 / 26695)
Q1M0P5 1.34e-117 350 46 4 385 1 metB Cystathionine gamma-synthase Helicobacter pylori
Q9WZY4 6.97e-115 345 44 6 428 1 TM_0882 O-acetyl-L-homoserine sulfhydrylase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Q9ZMW7 3.08e-114 341 45 4 385 3 metB Cystathionine gamma-synthase Helicobacter pylori (strain J99 / ATCC 700824)
P55218 7.39e-114 341 44 2 392 1 metZ O-succinylhomoserine sulfhydrylase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q60HG7 2.19e-112 337 46 5 389 2 CTH Cystathionine gamma-lyase Macaca fascicularis
A2RM21 2.65e-111 333 45 5 386 1 metC Cystathionine beta-lyase Lactococcus lactis subsp. cremoris (strain MG1363)
P0A4K2 2.65e-111 333 45 5 386 3 metC Cystathionine beta-lyase Lactococcus lactis subsp. lactis (strain IL1403)
Q8VCN5 6.15e-110 331 44 5 390 1 Cth Cystathionine gamma-lyase Mus musculus
O31632 6.45e-110 330 43 6 395 1 metC Cystathionine beta-lyase MetC Bacillus subtilis (strain 168)
P0C2T9 4.88e-109 328 45 5 386 1 metC Cystathionine beta-lyase Lactococcus lactis subsp. cremoris
Q19QT7 7.76e-109 328 45 5 390 2 CTH Cystathionine gamma-lyase Sus scrofa
P18757 1.05e-108 328 44 5 390 1 Cth Cystathionine gamma-lyase Rattus norvegicus
P9WGB7 3.4e-108 326 43 5 387 1 metB Cystathionine gamma-synthase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGB6 3.4e-108 326 43 5 387 3 metB Cystathionine gamma-synthase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P66876 3.4e-108 326 43 5 387 3 metB Cystathionine gamma-synthase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P94890 4.35e-108 328 42 6 428 1 metY O-acetyl-L-homoserine sulfhydrylase Leptospira meyeri
P55216 1.12e-104 317 44 6 393 3 cth-2 Putative cystathionine gamma-lyase 2 Caenorhabditis elegans
S0DUX5 1.22e-103 316 42 5 431 1 FUB7 Sulfhydrylase FUB7 Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831)
A0A0D2YG02 2.87e-103 315 44 4 431 1 FUB7 Sulfhydrylase FUB7 Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)
Q58DW2 3.41e-103 314 45 6 372 2 CTH Cystathionine gamma-lyase Bos taurus
W7MS09 3.52e-103 315 42 5 431 1 FUB7 Sulfhydrylase FUB7 Gibberella moniliformis (strain M3125 / FGSC 7600)
P46807 8.78e-102 310 41 3 386 3 metB Cystathionine gamma-synthase Mycobacterium leprae (strain TN)
Q79VI4 4.46e-101 310 41 5 423 1 metY O-acetyl-L-homoserine sulfhydrylase Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
O13326 1.75e-100 308 42 4 420 1 met17 Homocysteine synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P32929 1.11e-99 305 45 6 390 1 CTH Cystathionine gamma-lyase Homo sapiens
P55217 2.77e-99 309 40 3 383 1 CGS1 Cystathionine gamma-synthase 1, chloroplastic Arabidopsis thaliana
Q5SK88 5.74e-99 303 40 5 420 1 oah1 O-acetyl-L-homoserine sulfhydrylase 1 Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
P24601 1.06e-98 299 45 3 328 3 metB Probable cystathionine gamma-synthase (Fragment) Herpetosiphon aurantiacus
P9WGB5 1.58e-98 302 39 2 368 1 metZ O-succinylhomoserine sulfhydrylase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGB4 1.58e-98 302 39 2 368 3 metZ O-succinylhomoserine sulfhydrylase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P50125 5.37e-97 299 41 4 429 1 cysD Homocysteine synthase Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
P31373 1.16e-94 291 43 10 396 1 CYS3 Cystathionine gamma-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q5MNH8 1.04e-91 286 39 6 419 2 lolC2 Sulfhydrylase-like protein lolC2 Epichloe uncinata
P53780 5.24e-91 285 39 5 383 1 At3g57050 Cystathionine beta-lyase, chloroplastic Arabidopsis thaliana
Q92441 1.73e-90 283 40 8 434 3 MET17 Homocysteine/cysteine synthase Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
P44502 6.25e-89 276 41 8 387 3 metB Cystathionine gamma-synthase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q4L332 7.02e-88 274 41 6 367 1 metC Cystathionine beta-lyase MetC Staphylococcus haemolyticus (strain JCSC1435)
O31631 1.1e-87 273 37 5 386 1 metI Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase Bacillus subtilis (strain 168)
Q9C876 2.79e-87 273 37 3 376 3 CGS2 Probable cystathionine gamma-synthase 2 Arabidopsis thaliana
P00935 6.9e-86 269 39 3 388 1 metB Cystathionine gamma-synthase Escherichia coli (strain K12)
A0A0M3VI47 7.55e-86 271 37 5 387 1 CBL Cystathionine beta-lyase, chloroplastic Mimosa pudica
Q8J0B2 8.81e-86 271 39 6 425 2 lolC1 Sulfhydrylase-like protein lolC1 Epichloe uncinata
P0DXC4 9.71e-86 269 37 7 391 1 JFQ02_10020 Canavanine gamma-lyase Pseudomonas canavaninivorans
P0DXD3 1.91e-85 268 36 7 398 1 Rleg2_5066 Canavanine gamma-lyase Rhizobium leguminosarum bv. trifolii (strain WSM2304)
P06106 1.74e-83 265 38 7 438 1 MET17 Homocysteine/cysteine synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q9X0Z7 1.69e-80 255 38 6 387 1 aar L-alanine/L-glutamate racemase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Q5SJ58 4.9e-80 254 37 10 414 1 oah2 O-acetyl-L-homoserine sulfhydrylase 2 Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Q826W3 5.54e-79 252 41 11 397 1 mgl L-methionine gamma-lyase Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
A8CEI3 8.97e-79 252 37 6 375 1 None Mimosinase, chloroplastic Leucaena leucocephala
U6BYK3 1.21e-76 247 36 6 385 1 None Mimosinase, chloroplastic Mimosa pudica
O94350 3.25e-72 234 34 7 390 3 str3 Cystathionine beta-lyase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q1K8G0 8.83e-72 234 36 6 376 1 met-2 Cystathionine beta-lyase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Q07703 2.91e-69 226 33 7 404 1 metC Cystathionine beta-lyase Bordetella avium
Q52811 2.23e-64 214 32 7 399 3 metC Putative cystathionine beta-lyase Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841)
Q59829 9.77e-61 204 36 7 342 3 cysA Putative cystathionine gamma-lyase Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q73GL9 4.99e-60 202 31 8 402 1 aar L-alanine/L-glutamate racemase Wolbachia pipientis wMel
Q9SGU9 6.21e-57 196 36 10 357 1 MGL Methionine gamma-lyase Arabidopsis thaliana
P06721 2.06e-53 185 31 8 403 1 metC Cystathionine beta-lyase MetC Escherichia coli (strain K12)
P18949 7.7e-53 183 31 7 403 3 metC Cystathionine beta-lyase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P44527 1.56e-51 180 29 8 401 3 metC Cystathionine beta-lyase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P53101 2.54e-49 176 31 12 414 1 STR3 Cystathionine beta-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P43623 7.13e-40 148 28 4 336 1 IRC7 Putative cystathionine beta-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P38716 4.43e-30 122 28 14 395 1 YHR112C Uncharacterized trans-sulfuration enzyme YHR112C Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
O42851 7.63e-26 110 28 14 404 1 SPAC23A1.14c Uncharacterized trans-sulfuration enzyme C23A1.14c Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P38675 3.31e-13 74 28 6 246 3 met-7 Cystathionine gamma-synthase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
G8XHD7 3.76e-11 68 26 8 244 1 besB L-2-amino-4-chloropent-4-enoate dechlorinase/desaturase Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057)
O74314 6.12e-11 67 25 6 235 3 SPBC15D4.09c Probable cystathionine gamma-synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A0A0C2WKN7 1.46e-10 66 22 14 401 2 iboG1 Cystathionine gamma-synthase-like enzyme iboG1 Amanita muscaria (strain Koide BX008)
P47164 2.05e-10 66 26 10 262 1 STR2 Cystathionine gamma-synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q04533 8.25e-10 64 26 13 305 1 YML082W Putative cystathionine gamma-synthase YML082W Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A0A397HQN2 1.36e-09 63 22 10 352 1 ankD Cystathionine gamma-synthase-like protein ankD Aspergillus thermomutatus
Q12198 1.13e-08 60 25 15 356 1 HSU1 Homocysteine/cysteine synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A0A2I1D2M7 1.68e-05 50 22 12 283 3 ungC' Alanine racemase ungC' Aspergillus campestris (strain IBT 28561)
A0A2V5GUR2 7.57e-05 48 36 1 69 1 ungC Alanine racemase ungC Aspergillus violaceofuscus (strain CBS 115571)

  • Number of RefSeq hits:

General

Source Morganella morganii S2
Locus tag EHELCC_14960
Feature type CDS
Gene megL
Product methionine gamma-lyase
Location 87393 - 88589 (strand: -1)
Length 1197 (nucleotides) / 398 (amino acids)

Contig

Accession ZDB_225
Length 129223 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_92
Orthogroup size 12
N. genomes 6

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Genomic region

Domains

PF01053 Cys/Met metabolism PLP-dependent enzyme

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0626 Amino acid transport and metabolism (E) E Cystathionine beta-lyase/cystathionine gamma-synthase

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01761 methionine-gamma-lyase [EC:4.4.1.11] Cysteine and methionine metabolism
Selenocompound metabolism
Metabolic pathways		 -

Protein Sequence

MHDYTNKGYDTKIVHAGQQADPLTGALSTPIYQTSTFVFDSAAQGAARFALEEEGYIYSRLGNPTNAALEEKMRVLENGEAALATSSGIAAISTTILTMCGQGDHIVASDTLYGCTYALLSHTLPKFGIEVTFVRANDPANIKAAMKPNTKMVYVETPANPTLAMIDLEAAANVAHEGGAMLVVDNTFMSPYCQRPLELGADIVVHSVTKYINGHGDVIGGVIVGPADFLVPARLVGVKDITGGVMSPFNAWLTLRGLKTLHVRMERHCSNAMKVAKYLESNPNVEAVFYPGLPSHPQHELAKKQMSNFGGMISFEIKGGIEAGRKVMDSVELCMLAVSLGDTETLIQHPASMTHSPVPAEERLKAGITDGLIRISVGLETPEDIIADLEQAIAKAVA

Flanking regions ( +/- flanking 50bp)

GCAACAACAACACATGTTGGCATAATAAAAAATTATTCTTTGGAGGATTTATGCACGATTATACGAATAAAGGTTATGACACTAAGATTGTTCACGCTGGCCAGCAGGCTGATCCACTGACTGGTGCGTTATCAACCCCAATCTATCAGACCTCTACATTCGTCTTCGACAGCGCAGCACAAGGGGCAGCACGTTTCGCATTAGAAGAAGAAGGTTATATCTACTCACGTTTAGGTAACCCTACTAACGCAGCATTAGAAGAAAAAATGCGTGTACTGGAAAACGGCGAAGCAGCTCTGGCGACTTCTTCCGGTATCGCAGCTATCTCTACCACTATCCTGACTATGTGCGGCCAGGGCGACCATATCGTTGCTTCTGACACTCTGTACGGCTGTACTTATGCTCTGCTGTCTCACACCCTGCCTAAATTCGGTATCGAAGTCACTTTCGTTCGTGCAAATGACCCTGCGAACATCAAAGCGGCGATGAAACCAAACACCAAAATGGTTTACGTCGAAACTCCGGCTAACCCGACTCTGGCAATGATCGATCTCGAAGCAGCGGCAAATGTTGCTCACGAAGGCGGCGCAATGCTGGTTGTGGATAACACCTTTATGTCTCCGTACTGCCAGCGTCCTCTGGAATTAGGTGCAGACATCGTGGTTCACAGCGTAACCAAATACATCAACGGCCACGGCGACGTTATCGGTGGTGTGATTGTCGGTCCTGCTGACTTCCTGGTTCCTGCCCGTCTGGTTGGTGTTAAAGACATCACCGGTGGCGTAATGAGCCCGTTCAACGCATGGTTAACCCTGCGTGGTCTGAAAACACTGCACGTCCGTATGGAACGTCACTGCTCTAACGCAATGAAAGTGGCTAAATATCTGGAATCTAACCCGAACGTAGAAGCAGTATTCTACCCTGGTCTGCCGTCTCACCCGCAGCACGAGTTAGCGAAAAAACAGATGAGCAACTTCGGCGGTATGATCAGCTTTGAAATCAAAGGCGGTATCGAAGCAGGCCGTAAAGTGATGGACTCTGTTGAGTTATGCATGCTGGCAGTAAGCCTGGGCGATACTGAAACTCTGATTCAGCACCCTGCATCAATGACTCACTCTCCGGTTCCGGCTGAAGAGCGTCTGAAAGCAGGTATCACCGATGGTCTGATTCGTATCTCTGTCGGTCTGGAAACACCTGAAGACATCATTGCTGACCTGGAACAGGCTATTGCGAAAGCAGTTGCTTAAGACCAGAGCGGAAAATTAAGTCCTGCAGTATGTACTCACCTCATTTGCCG