Homologs in group_246

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7 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_02995 FBDBKF_02995 100.0 Morganella morganii S1 gadA Glutamate or tyrosine decarboxylase or a related PLP-dependent protein
NLDBIP_07865 NLDBIP_07865 100.0 Morganella morganii S4 gadA Glutamate or tyrosine decarboxylase or a related PLP-dependent protein
LHKJJB_07400 LHKJJB_07400 100.0 Morganella morganii S3 gadA Glutamate or tyrosine decarboxylase or a related PLP-dependent protein
HKOGLL_03530 HKOGLL_03530 100.0 Morganella morganii S5 gadA Glutamate or tyrosine decarboxylase or a related PLP-dependent protein
F4V73_RS11910 F4V73_RS11910 92.1 Morganella psychrotolerans - pyridoxal-dependent decarboxylase
PMI_RS05835 PMI_RS05835 25.8 Proteus mirabilis HI4320 disA swarming inhibition tyrosine decarboxylase DisA
PMI_RS11930 PMI_RS11930 71.2 Proteus mirabilis HI4320 - pyridoxal-dependent decarboxylase

Distribution of the homologs in the orthogroup group_246

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_246

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q5E6F9 3.3e-15 82 24 11 362 1 panP Aspartate 1-decarboxylase Aliivibrio fischeri (strain ATCC 700601 / ES114)
Q0W498 2.99e-14 78 25 10 330 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)
P48321 1.85e-13 76 23 6 314 2 GAD2 Glutamate decarboxylase 2 Sus scrofa
O28275 1.85e-13 75 24 12 326 3 mfnA Probable L-aspartate decarboxylase Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
Q05683 2.16e-13 76 23 8 344 1 Gad2 Glutamate decarboxylase 2 Rattus norvegicus
A0A481NV25 2.3e-13 76 26 18 396 1 tdc L-tyrosine decarboxylase Enterococcus faecium
Q60358 2.77e-13 75 28 10 279 1 mfnA L-tyrosine/L-aspartate decarboxylase Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
I0DFJ0 3.77e-13 75 25 12 352 1 None Aromatic-L-amino-acid decarboxylase Bacillus atrophaeus
Q4PRC2 4.24e-13 75 23 6 312 2 GAD2 Glutamate decarboxylase 2 Canis lupus familiaris
P48320 6.4e-13 75 23 6 311 1 Gad2 Glutamate decarboxylase 2 Mus musculus
P71362 7.12e-13 74 21 9 374 1 ddc L-2,4-diaminobutyrate decarboxylase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P48319 9.79e-13 74 24 9 321 2 GAD1 Glutamate decarboxylase 1 Sus scrofa
Q9UZD5 9.83e-13 73 25 12 332 3 mfnA Probable L-aspartate decarboxylase Pyrococcus abyssi (strain GE5 / Orsay)
Q05329 1.27e-12 74 23 6 314 1 GAD2 Glutamate decarboxylase 2 Homo sapiens
Q43908 1.3e-12 73 22 11 377 1 ddc L-2,4-diaminobutyrate decarboxylase Acinetobacter baumannii
P14748 2.47e-12 73 23 7 320 2 GAD1 Glutamate decarboxylase 1 Felis catus
A0PA85 2.49e-12 73 23 7 320 2 GAD1 Glutamate decarboxylase 1 Canis lupus familiaris
P18088 3.44e-12 72 23 7 320 1 Gad1 Glutamate decarboxylase 1 Rattus norvegicus
O58679 3.94e-12 71 25 12 332 1 mfnA L-aspartate/L-glutamate decarboxylase Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Q5IS68 4.32e-12 72 23 7 320 2 GAD1 Glutamate decarboxylase 1 Pan troglodytes
P48318 4.67e-12 72 23 7 320 1 Gad1 Glutamate decarboxylase 1 Mus musculus
Q0VCA1 5.14e-12 72 23 8 320 2 GAD1 Glutamate decarboxylase 1 Bos taurus
Q99259 7.68e-12 71 23 7 320 1 GAD1 Glutamate decarboxylase 1 Homo sapiens
Q5R7S7 8.46e-12 71 23 7 320 2 GAD1 Glutamate decarboxylase 1 Pongo abelii
J7GQ11 1.06e-11 71 23 11 379 1 tdc L-tyrosine decarboxylase Levilactobacillus brevis
A0B9M9 1.11e-11 70 24 14 326 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)
Q5JJ82 2.67e-11 69 24 12 321 1 mfnA L-aspartate decarboxylase Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Q2NHY7 4.33e-11 68 26 13 315 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
A4G060 4.33e-11 68 24 13 326 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
A5ULW4 1.16e-10 67 24 14 334 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)
O27188 1.41e-10 66 23 14 342 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
C5A2X8 2.39e-10 66 25 11 300 3 mfnA Probable L-aspartate decarboxylase Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
A7B1V0 2.82e-10 66 24 14 342 1 RUMGNA_01526 Tryptophan decarboxylase Mediterraneibacter gnavus (strain ATCC 29149 / DSM 114966 / JCM 6515 / VPI C7-9)
A3CWM4 3.03e-10 65 22 13 329 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Q6M0Y7 3.47e-10 65 23 12 326 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL)
E9FCP7 3.72e-10 66 24 11 319 3 dtxS4 L-aspartate decarboxylase dtxS4 Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075)
Q8U1P6 5.41e-10 65 24 11 323 3 mfnA Probable L-aspartate decarboxylase Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Q9Z3R1 1.02e-09 64 22 9 323 3 rhbB L-2,4-diaminobutyrate decarboxylase Rhizobium meliloti (strain 1021)
B8GDM7 1.22e-09 63 23 17 379 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Q838D6 1.27e-09 64 21 11 385 1 tdc L-tyrosine decarboxylase Enterococcus faecalis (strain ATCC 700802 / V583)
P0DTQ4 1.27e-09 64 21 11 385 1 tyrDC L-tyrosine decarboxylase Enterococcus faecalis (strain EnGen0310 / MMH594)
A6URB4 1.42e-09 63 23 11 326 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
A6UVR4 2.25e-09 63 26 6 193 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)
Q8TV92 1.77e-08 60 24 9 285 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
A6VIC0 1.84e-08 60 23 13 326 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
A0A0A2IDH4 2.29e-08 60 25 12 309 1 cnsB L-tryptophan decarboxylase cnsB Penicillium expansum
Q46DU3 4.64e-08 59 22 11 341 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanosarcina barkeri (strain Fusaro / DSM 804)
A2STQ3 5.04e-08 58 22 13 321 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
Q8PXA5 1.16e-07 57 21 11 351 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Q12VA2 1.94e-07 57 22 13 329 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
A7IAB9 3.16e-07 56 22 16 358 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)
Q8TUQ9 1.22e-06 54 21 9 310 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Q9HSA3 1.24e-06 54 23 10 292 3 mfnA Probable L-aspartate decarboxylase Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
B0R349 1.24e-06 54 23 10 292 3 mfnA Probable L-aspartate decarboxylase Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
I1RV23 1.27e-06 55 23 9 268 2 FG08083 Glutamate decarboxylase-like protein FG08083 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)
P05034 1.49e-06 54 22 7 312 1 hdc Histidine decarboxylase Morganella morganii
Q6ZQY3 2.47e-06 53 21 10 329 1 GADL1 Acidic amino acid decarboxylase GADL1 Homo sapiens
Q2FSD2 8.14e-06 52 25 15 322 3 mfnA Probable L-tyrosine/L-aspartate decarboxylase Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Q9LSH2 1.11e-05 52 27 7 204 2 GAD5 Glutamate decarboxylase 5 Arabidopsis thaliana
Q9Y194 1.35e-05 51 26 14 299 1 spl-1 Sphingosine-1-phosphate lyase Caenorhabditis elegans
A6QM00 1.36e-05 51 24 4 177 2 GADL1 Acidic amino acid decarboxylase GADL1 Bos taurus
Q1IAK7 1.6e-05 51 23 8 303 3 hdc Histidine decarboxylase Pseudomonas entomophila (strain L48)
Q9Y600 2.13e-05 50 24 6 168 1 CSAD Cysteine sulfinic acid decarboxylase Homo sapiens
Q07346 2.48e-05 50 27 7 204 1 GAD Glutamate decarboxylase Petunia hybrida
J7SZ64 2.94e-05 50 24 13 329 1 CLOSPO_02083 Tryptophan decarboxylase Clostridium sporogenes (strain ATCC 15579)
P20228 3.85e-05 50 21 13 355 1 Gad1 Glutamate decarboxylase Drosophila melanogaster
P28578 3.93e-05 49 22 8 313 3 hdc Histidine decarboxylase Raoultella planticola
Q28D99 4.2e-05 50 19 7 316 2 gadl1 Acidic amino acid decarboxylase GADL1 (Fragment) Xenopus tropicalis
O95470 5.66e-05 49 23 14 308 1 SGPL1 Sphingosine-1-phosphate lyase 1 Homo sapiens
Q5R4G0 6.9e-05 49 23 14 308 2 SGPL1 Sphingosine-1-phosphate lyase 1 Pongo abelii
Q8CHN6 0.000106 48 21 11 315 2 Sgpl1 Sphingosine-1-phosphate lyase 1 Rattus norvegicus
Q7X8D4 0.00014 48 22 12 380 3 LOC_Os04g04640 Serine decarboxylase 3 Oryza sativa subsp. japonica
Q8R0X7 0.000145 48 21 12 312 1 Sgpl1 Sphingosine-1-phosphate lyase 1 Mus musculus
P54767 0.000205 47 25 6 202 2 None Glutamate decarboxylase Solanum lycopersicum
P28577 0.000337 47 21 7 312 3 hdc Histidine decarboxylase Klebsiella aerogenes
P95477 0.000412 46 23 8 324 3 hdc Histidine decarboxylase Pseudomonas fluorescens
Q6ESZ9 0.000437 46 21 7 319 3 SDC1 Serine decarboxylase 1 Oryza sativa subsp. japonica

  • Number of RefSeq hits:

General

Source Morganella morganii S2
Locus tag EHELCC_07540
Feature type CDS
Gene gadA
Product Glutamate or tyrosine decarboxylase or a related PLP-dependent protein
Location 243343 - 245052 (strand: 1)
Length 1710 (nucleotides) / 569 (amino acids)

Contig

Accession ZDB_216
Length 269970 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_246
Orthogroup size 8
N. genomes 7

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Genomic region

Domains

PF00282 Pyridoxal-dependent decarboxylase conserved domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0076 Amino acid transport and metabolism (E) E Glutamate or tyrosine decarboxylase or a related PLP-dependent protein

Protein Sequence

MNQSELITLASANALNKDFEVKYQNVISDFFSRDPGKWPIFNHPQIQAITQFRQTTDADVQQINRYPQGKDLFAQLAGESHVRQNVIRPGEGQDDLLVFASALCKNWENPLAVENVIAMPSDPAVYGSMLGLLGNPNMVYCEYSGVADNMEKTVIRKVANLIGYDADKASGLFTQGGTMCNLYGYLFGIRKSLKQSKHLGMSVDQDFRIINSQGGHYSNMTNLSLLGVDITNKTIRIRVASDNTIDLADLEQQIRACYTVHCKIPVILLTAGTTDTFGVDEIKQVYDLRNRLCEEFEITEKPHIHVDAAVGWPIIFFIDYDFNTNPLAINDATLAGLRHNVEKFKQLKYADSITIDFHKWGYVPYTSSLVMVRDGDDFKALENDPENFTYFEHALEGQTHLQSTIECSRSGVGVFGAYAGLHYLGVEGYQTIIAHCLQNANYMRNQLLSMGNACVMVPENQGPSVGFRLYSPKLVNDPQAMFAHELTCAGDKTAYDMMVRNSRWHRELFLKRGKAGLFTNWVDSIACSAYAEHNRFAYIPGEKAVFMNPVTQRHHIDAFAKMLKTMSAE

Flanking regions ( +/- flanking 50bp)

CGCAAAGTAATGACATTACCTCAGCGTAATTTACTATTTTGGAGCTCATTGTGAATCAGTCAGAACTTATCACGCTCGCCTCTGCGAATGCGTTAAATAAAGATTTCGAAGTTAAATACCAAAACGTCATCAGTGATTTCTTCAGCCGGGATCCCGGCAAATGGCCGATTTTTAATCACCCGCAAATTCAGGCAATTACTCAGTTCCGCCAGACCACCGACGCGGATGTGCAGCAGATCAACCGCTATCCGCAGGGTAAGGATCTTTTTGCACAACTGGCCGGTGAGTCACATGTCCGTCAGAACGTGATCCGTCCGGGAGAAGGGCAGGATGATTTACTGGTGTTTGCGTCCGCGCTGTGCAAAAACTGGGAAAACCCGCTGGCCGTGGAAAACGTTATCGCCATGCCGTCAGACCCGGCAGTTTACGGCTCTATGCTGGGCTTGCTGGGTAACCCGAACATGGTGTACTGCGAATACTCCGGTGTGGCGGATAACATGGAAAAAACCGTTATCCGTAAAGTGGCCAATCTGATTGGCTATGATGCGGACAAAGCATCCGGTCTGTTCACCCAGGGCGGAACCATGTGCAATCTGTACGGCTATCTCTTCGGGATCCGTAAATCGCTGAAACAGTCAAAACATCTCGGGATGTCCGTTGATCAGGATTTCCGGATCATCAACTCACAGGGCGGTCACTACTCCAATATGACTAACCTGTCCCTGTTAGGTGTGGATATCACAAATAAAACAATCCGTATCCGGGTGGCGTCAGATAACACCATTGACCTGGCGGATCTGGAGCAGCAAATCCGTGCCTGCTATACCGTCCACTGTAAGATCCCGGTGATCCTGCTGACCGCGGGAACAACCGATACCTTTGGTGTCGATGAAATCAAACAGGTTTATGATCTGCGCAACCGCCTGTGTGAAGAGTTCGAAATTACAGAAAAACCGCATATTCACGTGGATGCGGCGGTCGGCTGGCCGATTATTTTCTTTATTGATTATGATTTTAACACCAACCCGCTGGCGATTAACGATGCCACCCTGGCTGGTCTGCGTCACAATGTTGAGAAATTTAAACAGCTGAAATATGCAGATTCCATCACTATCGACTTCCACAAATGGGGTTATGTGCCGTATACCTCGAGTCTGGTGATGGTGCGTGACGGTGATGATTTCAAAGCACTGGAAAATGACCCGGAAAACTTCACCTATTTTGAGCATGCGCTGGAAGGGCAGACTCACCTGCAATCCACCATTGAATGCAGCCGCAGCGGTGTCGGTGTGTTCGGCGCGTATGCCGGATTGCATTACCTGGGAGTTGAGGGTTATCAGACCATCATTGCGCACTGTCTGCAAAATGCGAACTACATGCGCAACCAGCTGTTATCCATGGGCAATGCCTGTGTGATGGTGCCGGAAAACCAGGGACCGAGTGTCGGTTTCCGCCTCTATTCACCGAAACTGGTGAATGATCCGCAGGCAATGTTTGCACACGAACTGACCTGTGCCGGAGATAAAACGGCCTATGACATGATGGTGCGCAACAGCCGCTGGCATCGTGAGCTGTTCCTGAAACGCGGTAAAGCAGGACTGTTTACCAACTGGGTGGATTCTATCGCCTGCTCGGCCTATGCGGAGCATAACCGGTTCGCGTATATTCCGGGGGAAAAGGCGGTCTTTATGAACCCGGTGACGCAGCGTCATCATATCGATGCATTTGCAAAAATGCTTAAAACCATGAGTGCAGAATAAAAAAGGGTGTTTTTTTCTTTTCTGTTTGTGGTATAAGAGAAAAAGAGCGT