VFG049099
Help to interpret the results
Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Virulence factor VFG049099
Protein list: lists the 2 occurences of the Virulence factor within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Virulence factor of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factor has been clustered.
Orthogroups are shown in red if they are annotated with that particular Virulence factor in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Virulence factor prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factor.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factor prediction.
Description
| Protein |
NAD-dependent epimerase |
| VF ID |
VF0561 |
| Category |
Immune modulation |
| Protein ID |
WP_014230054 |
| Characteristics |
In K. pneumoniae there are nine main O-serotypes. Three of these, O1, O2, and O3, are responsible for almost 80% of all Klebsiella infections.; Compared with other Enterobacteriaceae, such as Escherichia coli 161 defined O serotypes and Shigella flexneri at least 47 O serotypes, Klebsiella has a surprisingly low number of reported O serotypes which promises a more viable alternative for vaccine development compared with K-antigen-based vaccines; The O-antigen biosynthesis enzymes are encoded on the rfb locus. |
| Function |
Resistant to serum complement; also play a role in protecting bacteria from antimicrobial peptides, including polymyxin antibiotics |
| Vf_category_id |
VFC0258 |
Occurence in the database
| VFG049099 is associated with 2 different
proteins
|
|
The 2 proteins are classified into 1 different orthogroup(s)
|
|
Orthogroup |
Locus |
Start |
Stop |
S. |
Gene |
Product |
Organism |
| 0 |
group_249 |
PMI_RS07210 |
1579323 |
1580330 |
-1 |
|
NAD-dependent epimerase |
Proteus mirabilis HI4320 |
| 1 |
group_249 |
PMI_RS15765 |
3500964 |
3501974 |
-1 |
|
NAD-dependent epimerase |
Proteus mirabilis HI4320 |
