VFG046612


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Virulence factor VFG046612
Protein list: lists the 7 occurences of the Virulence factor within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Virulence factor of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factor has been clustered.
Orthogroups are shown in red if they are annotated with that particular Virulence factor in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Virulence factor prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factor.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factor prediction.

Description

Protein ribulose-phosphate 3-epimerase
VF ID VF0543
Category Immune modulation
Protein ID WP_014548584
Characteristics Group 4 capsule; high molecular weight (HMW) O-antigen capsule
Structure A polymer of the tetrasaccharide repeat, 4)-a-D-GalNAcAN-(1-.4)-a-D-GalNAcAN-(1-.3)-b-D-QuiNAc-(1-.2)-b-D-Qui4NFm-(1-, which is identical to F. tularensis O-antigen subunit; F. tularensis synthesizes an O-antigen capsule containing approximately 125 to 300 or more O-antigen repeating units
Function Providing a stealth shield that prevents the host immune system from detecting this potent pathogen
Vf_category_id VFC0258

Occurence in the database

VFG046612 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1645 FBDBKF_10430 42200 42874 1 rpe ribulose-phosphate 3-epimerase Morganella morganii S1
1 group_1645 EHELCC_14765 42190 42864 1 rpe ribulose-phosphate 3-epimerase Morganella morganii S2
2 group_1645 NLDBIP_14595 42190 42864 1 rpe ribulose-phosphate 3-epimerase Morganella morganii S4
3 group_1645 LHKJJB_14750 98862 99536 -1 rpe ribulose-phosphate 3-epimerase Morganella morganii S3
4 group_1645 HKOGLL_13370 98862 99536 -1 rpe ribulose-phosphate 3-epimerase Morganella morganii S5
5 group_1645 F4V73_RS14125 38934 39608 1 rpe ribulose-phosphate 3-epimerase Morganella psychrotolerans
6 group_1645 PMI_RS14990 3327016 3327690 1 rpe ribulose-phosphate 3-epimerase Proteus mirabilis HI4320