VFG046612


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Virulence factors VFG046612, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Virulence factors within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Virulence factor(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factors has been clustered.
In red the Virulence factors with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Virulence factors prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factors.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factors prediction.

Description

Protein ribulose-phosphate 3-epimerase
VF ID VF0543
Category Immune modulation
Protein ID WP_014548584
Characteristics Group 4 capsule; high molecular weight (HMW) O-antigen capsule
Structure A polymer of the tetrasaccharide repeat, 4)-a-D-GalNAcAN-(1-.4)-a-D-GalNAcAN-(1-.3)-b-D-QuiNAc-(1-.2)-b-D-Qui4NFm-(1-, which is identical to F. tularensis O-antigen subunit; F. tularensis synthesizes an O-antigen capsule containing approximately 125 to 300 or more O-antigen repeating units
Function Providing a stealth shield that prevents the host immune system from detecting this potent pathogen
Vf_category_id VFC0258

Occurence in the database

VFG046612 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1598 FBDBKF_10430 42200 42874 1 rpe ribulose-phosphate 3-epimerase Morganella morganii S1
1 group_1598 EHELCC_14765 42190 42864 1 rpe ribulose-phosphate 3-epimerase Morganella morganii S2
2 group_1598 NLDBIP_14595 42190 42864 1 rpe ribulose-phosphate 3-epimerase Morganella morganii S4
3 group_1598 LHKJJB_14750 98862 99536 -1 rpe ribulose-phosphate 3-epimerase Morganella morganii S3
4 group_1598 HKOGLL_13370 98862 99536 -1 rpe ribulose-phosphate 3-epimerase Morganella morganii S5
5 group_1598 F4V73_RS14125 38934 39608 1 rpe ribulose-phosphate 3-epimerase Morganella psychrotolerans
6 group_1598 PMI_RS14990 3327016 3327690 1 rpe ribulose-phosphate 3-epimerase Proteus mirabilis HI4320