VFG045346


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Virulence factors VFG045346, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Virulence factors within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Virulence factor(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factors has been clustered.
In red the Virulence factors with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Virulence factors prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factors.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factors prediction.

Description

Protein immunogenic lipoprotein A
VF ID VF0513
Category Adherence
Protein ID WP_011149697
Function Dual functions as an adhesin and an immunostimulant
Mechanism A lipoprotein that stimulates production of proinflammatory cytokines via TLR2 in human monocytes; involved in bacterial adherence to host cells
Vf_category_id VFC0001

Occurence in the database

VFG045346 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_5 FBDBKF_05895 2766 3581 1 metQ ABC-type metal ion transport system, periplasmic component/surface antigen Morganella morganii S1
1 group_5 EHELCC_08940 3338 4153 1 metQ ABC-type metal ion transport system, periplasmic component/surface antigen Morganella morganii S2
2 group_5 NLDBIP_09320 3338 4153 1 metQ ABC-type metal ion transport system, periplasmic component/surface antigen Morganella morganii S4
3 group_5 LHKJJB_08435 213085 213900 -1 metQ ABC-type metal ion transport system, periplasmic component/surface antigen Morganella morganii S3
4 group_5 HKOGLL_07985 213085 213900 -1 metQ ABC-type metal ion transport system, periplasmic component/surface antigen Morganella morganii S5
5 group_5 F4V73_RS16000 209874 210689 -1 MetQ/NlpA family lipoprotein Morganella psychrotolerans
6 group_5 PMI_RS11165 2456987 2457802 1 MetQ/NlpA family lipoprotein Proteus mirabilis HI4320