K03644


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K03644, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K03644
KO K03644
Description lipoyl synthase [EC:2.8.1.8]

KO part of 3 pathways

Lipoic acid metabolism
Metabolic pathways
Biosynthesis of cofactors

KO part of 4 modules

M00881 Cofactor and vitamin metabolism Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H
M00882 Cofactor and vitamin metabolism Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H
M00883 Cofactor and vitamin metabolism Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2
M00884 Cofactor and vitamin metabolism Lipoic acid biosynthesis, octanoyl-CoA => dihydrolipoyl-E2

Occurence in the database

K03644 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1561 PMI_RS02070 487404 488369 -1 lipA lipoyl synthase Proteus mirabilis HI4320
1 group_1561 FBDBKF_10110 114086 115051 1 lipA lipoyl synthase Morganella morganii S1
2 group_1561 EHELCC_04910 306051 307016 1 lipA lipoyl synthase Morganella morganii S2
3 group_1561 NLDBIP_04910 305847 306812 1 lipA lipoyl synthase Morganella morganii S4
4 group_1561 LHKJJB_13720 28566 29531 -1 lipA lipoyl synthase Morganella morganii S3
5 group_1561 HKOGLL_12815 114867 115832 1 lipA lipoyl synthase Morganella morganii S5
6 group_1561 F4V73_RS00225 56394 57359 -1 lipA lipoyl synthase Morganella psychrotolerans