K00658


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00658, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00658
KO K00658
Description 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]

KO part of 9 pathways

Citrate cycle (TCA cycle)
Lysine degradation
Tryptophan metabolism
Lipoic acid metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
2-Oxocarboxylic acid metabolism

KO part of 3 modules

M00009 Central carbohydrate metabolism Citrate cycle (TCA cycle, Krebs cycle)
M00011 Central carbohydrate metabolism Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00032 Lysine metabolism Lysine degradation, lysine => saccharopine => acetoacetyl-CoA

Occurence in the database

K00658 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1518 PMI_RS02805 616607 617815 1 odhB 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase Proteus mirabilis HI4320
1 group_1518 FBDBKF_09815 57462 58673 -1 odhB 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase Morganella morganii S1
2 group_1518 EHELCC_04615 249427 250638 -1 odhB 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase Morganella morganii S2
3 group_1518 NLDBIP_04615 249223 250434 -1 odhB 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase Morganella morganii S4
4 group_1518 LHKJJB_14015 84944 86155 1 odhB 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase Morganella morganii S3
5 group_1518 HKOGLL_12520 58243 59454 -1 odhB 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase Morganella morganii S5
6 group_1518 F4V73_RS00530 113830 115041 1 odhB 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase Morganella psychrotolerans