Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Diabetic cardiomyopathy Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Diabetic cardiomyopathy pathway
| KO | Description | All occurrences |
|---|---|---|
| K00036 | glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] | 7 |
| K00134 | glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] | 7 |
| K00161 | pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] | 0 |
| K00162 | pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] | 0 |
| K00234 | succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] | 0 |
| K00235 | succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1] | 0 |
| K00236 | succinate dehydrogenase (ubiquinone) cytochrome b560 subunit | 0 |
| K00237 | succinate dehydrogenase (ubiquinone) membrane anchor subunit | 0 |
| K00383 | glutathione reductase (NADPH) [EC:1.8.1.7] | 7 |
| K00411 | ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] | 0 |
| K00412 | ubiquinol-cytochrome c reductase cytochrome b subunit | 0 |
| K00413 | ubiquinol-cytochrome c reductase cytochrome c1 subunit | 0 |
| K00414 | ubiquinol-cytochrome c reductase core subunit 1 | 0 |
| K00415 | ubiquinol-cytochrome c reductase core subunit 2 | 0 |
| K00416 | ubiquinol-cytochrome c reductase subunit 6 | 0 |
| K00417 | ubiquinol-cytochrome c reductase subunit 7 | 0 |
| K00418 | ubiquinol-cytochrome c reductase subunit 8 | 0 |
| K00419 | ubiquinol-cytochrome c reductase subunit 9 | 0 |
| K00420 | ubiquinol-cytochrome c reductase subunit 10 | 0 |
| K00693 | glycogen synthase [EC:2.4.1.11] | 0 |
| K00820 | glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] | 7 |
| K00898 | pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] | 0 |
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 |
| K01110 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67] | 0 |
| K01283 | peptidyl-dipeptidase A [EC:3.4.15.1] | 0 |
| K01329 | chymase [EC:3.4.21.39] | 0 |
| K01379 | cathepsin D [EC:3.4.23.5] | 0 |
| K01380 | renin [EC:3.4.23.15] | 0 |
| K01398 | matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24] | 0 |
| K01403 | matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35] | 0 |
| K02125 | F-type H+-transporting ATPase subunit 8 | 0 |
| K02126 | F-type H+-transporting ATPase subunit a | 0 |
| K02127 | F-type H+-transporting ATPase subunit b | 0 |
| K02128 | F-type H+-transporting ATPase subunit c | 0 |
| K02131 | F-type H+-transporting ATPase subunit 6 | 0 |
| K02132 | F-type H+-transporting ATPase subunit alpha | 0 |
| K02133 | F-type H+-transporting ATPase subunit beta [EC:7.1.2.2] | 0 |
| K02134 | F-type H+-transporting ATPase subunit delta | 0 |
| K02135 | F-type H+-transporting ATPase subunit epsilon | 0 |
| K02136 | F-type H+-transporting ATPase subunit gamma | 0 |
| K02137 | F-type H+-transporting ATPase subunit O | 0 |
| K02138 | F-type H+-transporting ATPase subunit d | 0 |
| K02256 | cytochrome c oxidase subunit 1 [EC:7.1.1.9] | 0 |
| K02261 | cytochrome c oxidase subunit 2 | 0 |
| K02262 | cytochrome c oxidase subunit 3 | 0 |
| K02263 | cytochrome c oxidase subunit 4 | 0 |
| K02264 | cytochrome c oxidase subunit 5a | 0 |
| K02265 | cytochrome c oxidase subunit 5b | 0 |
| K02266 | cytochrome c oxidase subunit 6a | 0 |
| K02267 | cytochrome c oxidase subunit 6b | 0 |
| K02268 | cytochrome c oxidase subunit 6c | 0 |
| K02270 | cytochrome c oxidase subunit 7a | 0 |
| K02271 | cytochrome c oxidase subunit 7b | 0 |
| K02272 | cytochrome c oxidase subunit 7c | 0 |
| K02273 | cytochrome c oxidase subunit 8 | 0 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 |
| K02677 | classical protein kinase C alpha type [EC:2.7.11.13] | 0 |
| K03083 | glycogen synthase kinase 3 beta [EC:2.7.11.26] | 0 |
| K03878 | NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2] | 0 |
| K03879 | NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2] | 0 |
| K03880 | NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2] | 0 |
| K03881 | NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2] | 0 |
| K03882 | NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2] | 0 |
| K03883 | NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2] | 0 |
| K03884 | NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2] | 0 |
| K03934 | NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2] | 0 |
| K03935 | NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2] | 0 |
| K03936 | NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2] | 0 |
| K03937 | NADH dehydrogenase (ubiquinone) Fe-S protein 4 | 0 |
| K03938 | NADH dehydrogenase (ubiquinone) Fe-S protein 5 | 0 |
| K03939 | NADH dehydrogenase (ubiquinone) Fe-S protein 6 | 0 |
| K03940 | NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2] | 0 |
| K03941 | NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2] | 0 |
| K03942 | NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2] | 0 |
| K03943 | NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2] | 0 |
| K03944 | NADH dehydrogenase (ubiquinone) flavoprotein 3 | 0 |
| K03945 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1 | 0 |
| K03946 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2 | 0 |
| K03947 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3 | 0 |
| K03948 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4 | 0 |
| K03949 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5 | 0 |
| K03950 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6 | 0 |
| K03951 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7 | 0 |
| K03952 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8 | 0 |
| K03953 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9 | 0 |
| K03954 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10 | 0 |
| K03955 | NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein | 0 |
| K03956 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11 | 0 |
| K03957 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1 | 0 |
| K03958 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2 | 0 |
| K03959 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3 | 0 |
| K03960 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4 | 0 |
| K03961 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5 | 0 |
| K03962 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6 | 0 |
| K03963 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7 | 0 |
| K03964 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8 | 0 |
| K03965 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9 | 0 |
| K03966 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10 | 0 |
| K03967 | NADH dehydrogenase (ubiquinone) 1 subunit C1 | 0 |
| K03968 | NADH dehydrogenase (ubiquinone) 1 subunit C2 | 0 |
| K04166 | angiotensin II receptor type 1 | 0 |
| K04388 | TGF-beta receptor type-2 [EC:2.7.11.30] | 0 |
| K04392 | Ras-related C3 botulinum toxin substrate 1 | 0 |
| K04440 | mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] | 0 |
| K04441 | p38 MAP kinase [EC:2.7.11.24] | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 |
| K04500 | mothers against decapentaplegic homolog 2 | 0 |
| K04515 | calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] | 0 |
| K04526 | insulin | 0 |
| K04527 | insulin receptor [EC:2.7.10.1] | 0 |
| K04674 | TGF-beta receptor type-1 [EC:2.7.11.30] | 0 |
| K04684 | transcription factor Sp1 | 0 |
| K04735 | transcription factor p65 | 0 |
| K04962 | ryanodine receptor 2 | 0 |
| K05852 | phospholamban | 0 |
| K05853 | P-type Ca2+ transporter type 2A [EC:7.2.2.10] | 0 |
| K05858 | phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] | 0 |
| K05862 | voltage-dependent anion channel protein 1 | 0 |
| K05863 | solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 | 0 |
| K06068 | novel protein kinase C delta type [EC:2.7.11.13] | 0 |
| K06236 | collagen type I alpha | 0 |
| K06259 | CD36 antigen | 0 |
| K06269 | serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] | 0 |
| K07191 | MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4 | 0 |
| K07203 | serine/threonine-protein kinase mTOR [EC:2.7.11.1] | 0 |
| K07294 | peroxisome proliferator-activated receptor alpha | 0 |
| K07299 | MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1 | 0 |
| K07860 | Ras-related C3 botulinum toxin substrate 2 | 0 |
| K08009 | cytochrome b-245, alpha polypeptide | 0 |
| K08010 | neutrophil cytosolic factor 2 | 0 |
| K08011 | neutrophil cytosolic factor 1 | 0 |
| K08012 | neutrophil cytosolic factor 4 | 0 |
| K08766 | carnitine O-palmitoyltransferase 2 [EC:2.3.1.21] | 0 |
| K09565 | peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8] | 0 |
| K09821 | angiotensinogen | 0 |
| K11351 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11 | 0 |
| K11352 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12 | 0 |
| K11353 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13 | 0 |
| K12044 | troponin I, cardiac muscle | 0 |
| K13242 | nitric-oxide synthase, endothelial [EC:1.14.13.39] | 0 |
| K13375 | transforming growth factor beta-1 | 0 |
| K13376 | transforming growth factor beta-2 | 0 |
| K13377 | transforming growth factor beta-3 | 0 |
| K15040 | voltage-dependent anion channel protein 2 | 0 |
| K15041 | voltage-dependent anion channel protein 3 | 0 |
| K16172 | insulin receptor substrate 1 | 0 |
| K17605 | serine/threonine-protein phosphatase 2A activator | 0 |
| K17902 | TBC1 domain family member 4 | 0 |
| K18952 | atypical protein kinase C zeta type [EC:2.7.11.13] | 0 |
| K19523 | carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21] | 0 |
| K19662 | classical protein kinase C beta type [EC:2.7.11.13] | 0 |
| K19663 | classical protein kinase C gamma type [EC:2.7.11.13] | 0 |
| K19720 | collagen type III alpha | 0 |
| K19722 | receptor for advanced glycosylation end products | 0 |
| K21421 | NADPH oxidase 2 [EC:1.-.-.-] | 0 |
| K22138 | mitochondrial pyruvate carrier 1 | 0 |
| K22139 | mitochondrial pyruvate carrier 2 | 0 |
| K23605 | mothers against decapentaplegic homolog 3 | 0 |
| K24070 | poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] | 0 |