Central carbon metabolism in cancer
Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S5 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Central carbon metabolism in cancer Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Central carbon metabolism in cancer pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00016 | L-lactate dehydrogenase [EC:1.1.1.27] | 0 | 0 |
| K00031 | isocitrate dehydrogenase [EC:1.1.1.42] | 1 | 7 |
| K00036 | glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] | 1 | 7 |
| K00161 | pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] | 0 | 0 |
| K00162 | pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] | 0 | 0 |
| K00844 | hexokinase [EC:2.7.1.1] | 0 | 0 |
| K00850 | 6-phosphofructokinase 1 [EC:2.7.1.11] | 1 | 6 |
| K00873 | pyruvate kinase [EC:2.7.1.40] | 2 | 15 |
| K00922 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] | 0 | 0 |
| K01110 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67] | 0 | 0 |
| K01425 | glutaminase [EC:3.5.1.2] | 3 | 19 |
| K01834 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] | 1 | 7 |
| K02649 | phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | 0 | 0 |
| K02833 | GTPase HRas | 0 | 0 |
| K03176 | neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1] | 0 | 0 |
| K04361 | epidermal growth factor receptor [EC:2.7.10.1] | 0 | 0 |
| K04362 | fibroblast growth factor receptor 1 [EC:2.7.10.1] | 0 | 0 |
| K04363 | platelet-derived growth factor receptor alpha [EC:2.7.10.1] | 0 | 0 |
| K04366 | RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K04368 | mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] | 0 | 0 |
| K04369 | mitogen-activated protein kinase kinase 2 [EC:2.7.12.2] | 0 | 0 |
| K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] | 0 | 0 |
| K04377 | Myc proto-oncogene protein | 0 | 0 |
| K04451 | tumor protein p53 | 0 | 0 |
| K04456 | RAC serine/threonine-protein kinase [EC:2.7.11.1] | 0 | 0 |
| K05083 | receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1] | 0 | 0 |
| K05089 | platelet-derived growth factor receptor beta [EC:2.7.10.1] | 0 | 0 |
| K05091 | proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1] | 0 | 0 |
| K05092 | fms-related tyrosine kinase 3 [EC:2.7.10.1] | 0 | 0 |
| K05093 | fibroblast growth factor receptor 2 [EC:2.7.10.1] | 0 | 0 |
| K05094 | fibroblast growth factor receptor 3 [EC:2.7.10.1] | 0 | 0 |
| K05099 | proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] | 0 | 0 |
| K05101 | neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1] | 0 | 0 |
| K05126 | proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1] | 0 | 0 |
| K05616 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0 | 0 |
| K07203 | serine/threonine-protein kinase mTOR [EC:2.7.11.1] | 0 | 0 |
| K07299 | MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1 | 0 | 0 |
| K07593 | MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2 | 0 | 0 |
| K07827 | GTPase KRas | 0 | 0 |
| K07828 | GTPase NRas | 0 | 0 |
| K08180 | MFS transporter, MCT family, solute carrier family 16 (monocarboxylic acid transporters), member 3 | 0 | 0 |
| K08268 | hypoxia-inducible factor 1 alpha | 0 | 0 |
| K11413 | NAD-dependent protein deacetylase sirtuin 3 [EC:2.3.1.286] | 0 | 0 |
| K11416 | NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286] | 0 | 0 |
| K12077 | pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2] | 0 | 0 |
| K12407 | glucokinase [EC:2.7.1.2] | 0 | 0 |
| K13780 | solute carrier family 7 (L-type amino acid transporter), member 5 | 0 | 0 |
| K14634 | fructose-2,6-bisphosphatase [EC:3.1.3.46] | 0 | 0 |
| K23755 | protein SCO2 | 0 | 0 |