Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S4 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of beta-Lactam resistance Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the beta-Lactam resistance pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00687 | penicillin-binding protein 2B | 0 | 0 |
| K01207 | beta-N-acetylhexosaminidase [EC:3.2.1.52] | 2 | 12 |
| K01467 | beta-lactamase class C [EC:3.5.2.6] | 0 | 1 |
| K02171 | BlaI family transcriptional regulator, penicillinase repressor | 0 | 0 |
| K02172 | bla regulator protein blaR1 | 0 | 0 |
| K02545 | penicillin-binding protein 2 prime [EC:3.4.16.4] | 0 | 0 |
| K02546 | BlaI family transcriptional regulator, methicillin resistance regulatory protein | 0 | 0 |
| K02547 | methicillin resistance protein | 0 | 0 |
| K03585 | membrane fusion protein, multidrug efflux system | 1 | 8 |
| K03587 | cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] | 1 | 7 |
| K03693 | penicillin-binding protein 1B | 0 | 0 |
| K05366 | penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] | 1 | 7 |
| K05515 | penicillin-binding protein 2 [EC:3.4.16.4] | 1 | 7 |
| K08218 | MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG | 1 | 7 |
| K08720 | outer membrane protein OmpU | 0 | 0 |
| K09475 | outer membrane pore protein C | 0 | 0 |
| K09476 | outer membrane pore protein F | 1 | 5 |
| K10823 | oligopeptide transport system ATP-binding protein | 0 | 0 |
| K12340 | outer membrane protein | 1 | 7 |
| K12552 | penicillin-binding protein 1 [EC:3.4.-.-] | 0 | 0 |
| K12553 | penicillin-binding protein 3 [EC:3.4.-.-] | 0 | 0 |
| K12555 | penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] | 0 | 0 |
| K12556 | penicillin-binding protein 2X | 0 | 0 |
| K15580 | oligopeptide transport system substrate-binding protein | 3 | 21 |
| K15581 | oligopeptide transport system permease protein | 1 | 7 |
| K15582 | oligopeptide transport system permease protein | 1 | 7 |
| K15583 | oligopeptide transport system ATP-binding protein | 1 | 7 |
| K17836 | beta-lactamase class A [EC:3.5.2.6] | 0 | 0 |
| K17837 | metallo-beta-lactamase class B [EC:3.5.2.6] | 0 | 0 |
| K17838 | beta-lactamase class D [EC:3.5.2.6] | 0 | 0 |
| K17850 | LysR family transcriptional regulator, regulator of gene expression of beta-lactamase | 1 | 6 |
| K18072 | two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3] | 0 | 0 |
| K18073 | two-component system, OmpR family, response regulator ParR | 0 | 0 |
| K18093 | imipenem/basic amino acid-specific outer membrane pore [EC:3.4.21.-] | 0 | 0 |
| K18094 | membrane fusion protein, multidrug efflux system | 0 | 0 |
| K18095 | multidrug efflux pump | 0 | 0 |
| K18104 | ATP-binding cassette, subfamily B, bacterial AbcA/BmrA [EC:7.6.2.2] | 0 | 0 |
| K18129 | TetR/AcrR family transcriptional regulator, mexXY operon repressor | 0 | 0 |
| K18130 | TetR/AcrR family transcriptional regulator, transcriptional repressor NalC | 1 | 6 |
| K18131 | MarR family transcriptional regulator, repressor of the mexAB-oprM multidrug resistance operon | 0 | 0 |
| K18133 | major outer membrane protein P.IB | 0 | 0 |
| K18135 | TetR/AcrR family transcriptional regulator, repressor of the mexAB-oprM multidrug resistance operon | 0 | 0 |
| K18136 | TetR/AcrR family transcriptional regulator, multidrug resistance operon repressor | 0 | 0 |
| K18137 | TetR/AcrR family transcriptional regulator, repressor of the adeIJK operon | 0 | 0 |
| K18138 | multidrug efflux pump | 1 | 8 |
| K18139 | outer membrane protein, multidrug efflux system | 0 | 0 |
| K18143 | two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3] | 0 | 0 |
| K18144 | two-component system, OmpR family, response regulator AdeR | 0 | 0 |
| K18145 | membrane fusion protein, multidrug efflux system | 0 | 0 |
| K18146 | multidrug efflux pump | 0 | 0 |
| K18147 | outer membrane protein, multidrug efflux system | 0 | 0 |
| K18148 | release factor H-coupled RctB family protein | 1 | 6 |
| K18149 | penicillin-binding protein | 0 | 0 |
| K18150 | antirepressor for MexR | 0 | 0 |
| K18698 | beta-lactamase class A TEM [EC:3.5.2.6] | 0 | 2 |
| K18699 | beta-lactamase class A SHV [EC:3.5.2.6] | 0 | 0 |
| K18766 | beta-lactamase class A BlaZ [EC:3.5.2.6] | 0 | 0 |
| K18767 | beta-lactamase class A CTX-M [EC:3.5.2.6] | 0 | 2 |
| K18768 | beta-lactamase class A KPC [EC:3.5.2.6] | 0 | 0 |
| K18780 | metallo-beta-lactamase class B NDM [EC:3.5.2.6] | 1 | 4 |
| K18781 | metallo-beta-lactamase class B VIM [EC:3.5.2.6] | 0 | 0 |
| K18782 | metallo-beta-lactamase class B IMP [EC:3.5.2.6] | 0 | 0 |
| K18790 | beta-lactamase class D OXA-1 [EC:3.5.2.6] | 0 | 2 |
| K18791 | beta-lactamase class D OXA-2 [EC:3.5.2.6] | 0 | 0 |
| K18792 | beta-lactamase class D OXA-10 [EC:3.5.2.6] | 0 | 0 |
| K18793 | beta-lactamase class D OXA-23 [EC:3.5.2.6] | 0 | 0 |
| K18794 | beta-lactamase class D OXA-51 [EC:3.5.2.6] | 0 | 0 |
| K18795 | beta-lactamase class A CARB-1, PSE family [EC:3.5.2.6] | 0 | 0 |
| K18796 | beta-lactamase class A LEN [EC:3.5.2.6] | 0 | 0 |
| K18797 | beta-lactamase class A PER [EC:3.5.2.6] | 0 | 0 |
| K18970 | beta-lactamase class A GES [EC:3.5.2.6] | 0 | 0 |
| K18971 | beta-lactamase class D OXA-24 [EC:3.5.2.6] | 0 | 0 |
| K18972 | beta-lactamase class D OXA-58 [EC:3.5.2.6] | 0 | 0 |
| K18973 | beta-lactamase class D OXA-50 [EC:3.5.2.6] | 0 | 0 |
| K18976 | beta-lactamase class D OXA-48 [EC:3.5.2.6] | 0 | 0 |
| K19095 | beta-lactamase class C CMY-1 [EC:3.5.2.6] | 0 | 0 |
| K19096 | beta-lactamase class C CMY-2 [EC:3.5.2.6] | 0 | 0 |
| K19097 | beta-lactamase class A VEB [EC:3.5.2.6] | 0 | 0 |
| K19098 | beta-lactamase class D OXA-9 [EC:3.5.2.6] | 0 | 0 |
| K19099 | metallo-beta-lactamase class B GIM [EC:3.5.2.6] | 0 | 0 |
| K19100 | beta-lactamase class C DHA [EC:3.5.2.6] | 1 | 5 |
| K19101 | beta-lactamase class C FOX [EC:3.5.2.6] | 0 | 0 |
| K19209 | beta-lactamase class D OXA-42 [EC:3.5.2.6] | 0 | 0 |
| K19210 | beta-lactamase class D OXA-61 [EC:3.5.2.6] | 0 | 0 |
| K19211 | beta-lactamase class D OXA-62 [EC:3.5.2.6] | 0 | 0 |
| K19212 | beta-lactamase class D OXA-63 [EC:3.5.2.6] | 0 | 0 |
| K19213 | beta-lactamase class D OXA-12 [EC:3.5.2.6] | 0 | 0 |
| K19214 | beta-lactamase class C ACC [EC:3.5.2.6] | 0 | 0 |
| K19215 | beta-lactamase class C ACT/MIR [EC:3.5.2.6] | 0 | 0 |
| K19216 | metallo-beta-lactamase class B IND [EC:3.5.2.6] | 0 | 0 |
| K19217 | beta-lactamase class A CARB-17 [EC:3.5.2.6] | 0 | 0 |
| K19218 | beta-lactamase class A CARB-5, RTG family [EC:3.5.2.6] | 0 | 0 |
| K19316 | beta-lactamase class A IMI [EC:3.5.2.6] | 0 | 0 |
| K19317 | beta-lactamase class A BEL [EC:3.5.2.6] | 0 | 0 |
| K19318 | beta-lactamase class D OXA-213 [EC:3.5.2.6] | 0 | 0 |
| K19319 | beta-lactamase class D OXA-134 [EC:3.5.2.6] | 0 | 0 |
| K19320 | beta-lactamase class D OXA-211 [EC:3.5.2.6] | 0 | 0 |
| K19321 | beta-lactamase class D OXA-214 [EC:3.5.2.6] | 0 | 0 |
| K19322 | beta-lactamase class D OXA-229 [EC:3.5.2.6] | 0 | 0 |
| K20319 | beta-lactamase class C ADC [EC:3.5.2.6] | 0 | 0 |
| K20320 | beta-lactamase class C PDC [EC:3.5.2.6] | 0 | 0 |
| K21266 | beta-lactamase class D OXA-286 [EC:3.5.2.6] | 0 | 0 |
| K21276 | beta-lactamase class D OXA-22 [EC:3.5.2.6] | 0 | 0 |
| K21277 | beta-lactamase class D OXA-60 [EC:3.5.2.6] | 0 | 0 |
| K22331 | beta-lactamase class D OXA-184 [EC:3.5.2.6] | 0 | 0 |
| K22332 | beta-lactamase class D OXA-548 [EC:3.5.2.6] | 0 | 0 |
| K22333 | beta-lactamase class D OXA-493 [EC:3.5.2.6] | 0 | 0 |
| K22334 | beta-lactamase class D OXA-464 [EC:3.5.2.6] | 0 | 0 |
| K22335 | beta-lactamase class D OXA-114 [EC:3.5.2.6] | 0 | 0 |
| K22346 | beta-lactamase class A SME [EC:3.5.2.6] | 0 | 0 |
| K22351 | beta-lactamase class D OXA-209 [EC:3.5.2.6] | 0 | 0 |
| K22352 | beta-lactamase class D OXA-29 [EC:3.5.2.6] | 0 | 0 |