Orthogroup:group_869


Homologs in group_869

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7 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Source Gene Product
FBDBKF_04410 FBDBKF_04410 Morganella morganii S1 leuA 2-isopropylmalate synthase
EHELCC_05700 EHELCC_05700 Morganella morganii S2 leuA 2-isopropylmalate synthase
NLDBIP_06020 NLDBIP_06020 Morganella morganii S4 leuA 2-isopropylmalate synthase
LHKJJB_02900 LHKJJB_02900 Morganella morganii S3 leuA 2-isopropylmalate synthase
HKOGLL_06375 HKOGLL_06375 Morganella morganii S5 leuA 2-isopropylmalate synthase
F4V73_RS08855 F4V73_RS08855 Morganella psychrotolerans leuA 2-isopropylmalate synthase
PMI_RS10265 PMI_RS10265 Proteus mirabilis HI4320 leuA 2-isopropylmalate synthase

Distribution of group_869 homologs

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Number of homologs in each genome (first column and blue bar chart)

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Phylogeny of group_869 (midpoint rooted)


Phylogeny of the RefSeq best hits of group_869

Orthogroup content: 7 members

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This page summarizes the annotation of all members of the orthologous group group_869.
Gene name(s), gene product(s), a summary of protein lenght, and annotations (when available) are provided. Additionally, the number of times (occurence) an annotation is observed in the orthogroup is reported for each annotation.

Orthologs were identified with OrthoFinder. The annotation of orthologous proteins can differ depending the approach used to annotate the source genomes. Automated annotations are also subject to errors. Spurious clustering of non-orthologous proteins can also happen. This page allows to check for eventual inconsistencies.

Gene

# Gene name Occurence
1 leuA 7

Product

# Product Occurence
1 2-isopropylmalate synthase 7

COG entry Annotation(s)

ID Occurences Function(s) cat. Function(s) descr. Description
COG0119 7 E Amino acid transport and metabolism (E) Isopropylmalate/homocitrate/citramalate synthases

Kegg Ortholog Annotation(s)

Pfam domain Annotation(s)

Domain ID Occurences Description
PF00682 7 HMGL-like
PF08502 7 LeuA allosteric (dimerisation) domain
PF22617 7 Homocitrate synthase post-HMGL domain-like

Annotations of the 508 SwissProt hits

Annotation Number of occurrences
(R)-citramalate synthase 6
(R)-citramalate synthase CimA 2
2-isopropylmalate synthase 389
2-isopropylmalate synthase (Fragment) 7
2-isopropylmalate synthase 1 2
2-isopropylmalate synthase 1, chloroplastic 1
2-isopropylmalate synthase 2 2
2-isopropylmalate synthase 2, chloroplastic 1
2-isopropylmalate synthase 2, mitochondrial 1
2-isopropylmalate synthase A 1
2-isopropylmalate synthase B 1
2-phosphonomethylmalate synthase 1
4-hydroxy-2-oxovalerate aldolase 24
4-hydroxy-2-oxovalerate aldolase 1 1
4-hydroxy-2-oxovalerate aldolase 2 2
4-hydroxy-2-oxovalerate aldolase 3 1
4-hydroxy-2-oxovalerate aldolase 7 1
Citrate (Re)-synthase 3
Homocitrate synthase 21
Homocitrate synthase 1 1
Homocitrate synthase 2 1
Homocitrate synthase AksA 5
Homocitrate synthase subunit alpha 1
Homocitrate synthase, cytosolic isozyme 1
Homocitrate synthase, mitochondrial 4
Hydroxymethylglutaryl-CoA lyase YngG 1
Hydroxymethylglutaryl-CoA lyase, mitochondrial 3
Isopropyl malate synthase AMT7 1
Isopropyl malate synthase gloH 1
Isopropyl malate synthase htyA 1
Methylthioalkylmalate synthase 1, chloroplastic 1
Methylthioalkylmalate synthase 1-1, chloroplastic 1
Methylthioalkylmalate synthase 1-2, chloroplastic 1
Methylthioalkylmalate synthase 2, chloroplastic 1
Methylthioalkylmalate synthase 3, chloroplastic 1
Probable 2-isopropylmalate synthase 8
Putative (R)-citramalate synthase CimA 7
Putative 2-isopropylmalate synthase 1

Protein length

Min length 519
Max length 537
Mean length (sd) 533.1 (7.1)
Median length 537.0

Protein length distribution