Orthogroup:group_1918



Homologs in group_1918

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7 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Source Gene Product
FBDBKF_14275 FBDBKF_14275 Morganella morganii S1 pdxB 4-phosphoerythronate dehydrogenase PdxB
EHELCC_08005 EHELCC_08005 Morganella morganii S2 pdxB 4-phosphoerythronate dehydrogenase PdxB
NLDBIP_08330 NLDBIP_08330 Morganella morganii S4 pdxB 4-phosphoerythronate dehydrogenase PdxB
LHKJJB_05935 LHKJJB_05935 Morganella morganii S3 pdxB 4-phosphoerythronate dehydrogenase PdxB
HKOGLL_04980 HKOGLL_04980 Morganella morganii S5 pdxB 4-phosphoerythronate dehydrogenase PdxB
F4V73_RS02635 F4V73_RS02635 Morganella psychrotolerans pdxB 4-phosphoerythronate dehydrogenase PdxB
PMI_RS08785 PMI_RS08785 Proteus mirabilis HI4320 pdxB 4-phosphoerythronate dehydrogenase PdxB

Distribution of group_1918 homologs

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Number of homologs in each genome (first column and blue bar chart)

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Phylogeny of group_1918 (midpoint rooted)


Phylogeny of the RefSeq best hits of group_1918

Orthogroup content: 7 members

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This page summarizes the annotation of all members of the orthologous group group_1918.
Gene name(s), gene product(s), a summary of protein lenght, and annotations (when available) are provided. Additionally, the number of times (occurence) an annotation is observed in the orthogroup is reported for each annotation.

Orthologs were identified with OrthoFinder. The annotation of orthologous proteins can differ depending the approach used to annotate the source genomes. Automated annotations are also subject to errors. Spurious clustering of non-orthologous proteins can also happen. This page allows to check for eventual inconsistencies.

Gene

# Gene name Occurence
1 pdxB 7

Product

# Product Occurence
1 4-phosphoerythronate dehydrogenase PdxB 7

COG entry Annotation(s)

ID Occurences Function(s) cat. Function(s) descr. Description
COG0111 7 H Coenzyme transport and metabolism (H) Phosphoglycerate dehydrogenase or related dehydrogenase

Kegg Ortholog Annotation(s)

KO Occurences Description Pathways Modules
K03473 7 erythronate-4-phosphate dehydrogenase [EC:1.1.1.290] Vitamin B6 metabolism
Metabolic pathways
Biosynthesis of cofactors
Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P

Pfam domain Annotation(s)

Domain ID Occurences Description
PF00389 7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PF02826 7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PF11890 7 Domain of unknown function (DUF3410)

Annotations of the 404 SwissProt hits

Annotation Number of occurrences
(R)-2-hydroxyglutarate dehydrogenase 1
(S)-sulfolactate dehydrogenase 1
2-hydroxyacid dehydrogenase A 1
2-hydroxyacid dehydrogenase homolog 2
2-hydroxyacid dehydrogenase homolog 1 1
2-hydroxyacid dehydrogenase homolog 2 1
2-ketogluconate reductase 1
4-methyl-2-oxopentanoate reductase A 1
Aromatic 2-oxoacid reductase 2
C-terminal-binding protein 1
C-terminal-binding protein 1 5
C-terminal-binding protein 2 5
D-2-hydroxyacid dehydrogenase 1
D-2-hydroxyacid dehydrogenase (NAD(+)) 1
D-2-hydroxyacid dehydrogenase (NAD+) 1
D-3-phosphoglycerate dehydrogenase 23
D-3-phosphoglycerate dehydrogenase 1 1
D-3-phosphoglycerate dehydrogenase 1, chloroplastic 1
D-3-phosphoglycerate dehydrogenase 2 1
D-3-phosphoglycerate dehydrogenase 2, chloroplastic 1
D-3-phosphoglycerate dehydrogenase 3, chloroplastic 1
D-lactate dehydrogenase 19
D-lactate dehydrogenase kk1H 1
D-lactate/D-glycerate dehydrogenase 1
D-specific alpha-keto acid dehydrogenase 2
Dehydrogenase efuE 1
Erythronate-4-phosphate dehydrogenase 153
Erythronate-4-phosphate dehydrogenase (Fragment) 1
Formate dehydrogenase 6
Formate dehydrogenase 1 4
Formate dehydrogenase 1, mitochondrial 1
Formate dehydrogenase 2 1
Formate dehydrogenase 2, mitochondrial 1
Formate dehydrogenase, chloroplastic/mitochondrial 1
Formate dehydrogenase, mitochondrial 2
Glycerate dehydrogenase 3
Glycerate dehydrogenase HPR, peroxisomal 1
Glyoxylate reductase 10
Glyoxylate reductase 1 1
Glyoxylate reductase/hydroxypyruvate reductase 2
Glyoxylate/hydroxypyruvate reductase A 46
Glyoxylate/hydroxypyruvate reductase A HPR2 1
Glyoxylate/hydroxypyruvate reductase B 62
Glyoxylate/hydroxypyruvate reductase HPR3 1
Glyoxylate/hydroxypyruvate/pyruvate reductase 2KGR 1
Hydroxyphenylpyruvate reductase 1
Hydroxypyruvate reductase 2
Phosphonate dehydrogenase 1
Probable 2-ketogluconate reductase 2
Putative 2-hydroxyacid dehydrogenase C1773.17c 1
Putative 2-hydroxyacid dehydrogenase HI_1556 1
Putative 2-hydroxyacid dehydrogenase MW2224 1
Putative 2-hydroxyacid dehydrogenase SA2098 1
Putative 2-hydroxyacid dehydrogenase SAB2178 1
Putative 2-hydroxyacid dehydrogenase SACOL2296 1
Putative 2-hydroxyacid dehydrogenase SAOUHSC_02577 1
Putative 2-hydroxyacid dehydrogenase SAR2389 1
Putative 2-hydroxyacid dehydrogenase SAS2196 1
Putative 2-hydroxyacid dehydrogenase SAUSA300_2254 1
Putative 2-hydroxyacid dehydrogenase SAV2305 1
Putative 2-hydroxyacid dehydrogenase SERP1888 1
Putative 2-hydroxyacid dehydrogenase SE_1879 1
Putative 2-hydroxyacid dehydrogenase SH0752 1
Putative 2-hydroxyacid dehydrogenase SSP0606 1
Putative 2-hydroxyacid dehydrogenase UNK4.10 1
Putative 2-hydroxyacid dehydrogenase YGL185C 1
Putative 2-hydroxyacid dehydrogenase YoaD 1
Putative D-3-phosphoglycerate dehydrogenase 1
Putative D-lactate dehydrogenase 1
Truncated formate dehydrogenase 2 1
Uncharacterized protein Cgl2355/cg2587 1
Uncharacterized protein in proB 3'region 1

Protein length

Min length 375
Max length 381
Mean length (sd) 379.4 (2.7)
Median length 381.0

Protein length distribution