Homologs in group_193

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8 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_09270 FBDBKF_09270 81.8 Morganella morganii S1 mET17 bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
EHELCC_10140 EHELCC_10140 81.8 Morganella morganii S2 mET17 bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
NLDBIP_10485 NLDBIP_10485 81.8 Morganella morganii S4 mET17 bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
LHKJJB_10870 LHKJJB_10870 81.8 Morganella morganii S3 mET17 bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
HKOGLL_13930 HKOGLL_13930 81.8 Morganella morganii S5 mET17 bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
F4V73_RS10695 F4V73_RS10695 82.5 Morganella psychrotolerans - bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
PMI_RS06025 PMI_RS06025 37.1 Proteus mirabilis HI4320 - cystathionine gamma-synthase family protein
PMI_RS11105 PMI_RS11105 43.2 Proteus mirabilis HI4320 - methionine gamma-lyase

Distribution of the homologs in the orthogroup group_193

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_193

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q9WZY4 2.55e-168 481 58 4 421 1 TM_0882 O-acetyl-L-homoserine sulfhydrylase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
W7MS09 8.83e-159 457 53 1 423 1 FUB7 Sulfhydrylase FUB7 Gibberella moniliformis (strain M3125 / FGSC 7600)
S0DUX5 3.57e-158 456 52 1 423 1 FUB7 Sulfhydrylase FUB7 Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831)
Q5SK88 1.9e-157 454 53 3 422 1 oah1 O-acetyl-L-homoserine sulfhydrylase 1 Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
A0A0D2YG02 2.28e-157 454 52 1 423 1 FUB7 Sulfhydrylase FUB7 Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)
P50125 6.81e-156 450 54 1 424 1 cysD Homocysteine synthase Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
O13326 1.45e-155 449 55 1 419 1 met17 Homocysteine synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q92441 3.42e-145 423 51 3 434 3 MET17 Homocysteine/cysteine synthase Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
P94890 5.7e-145 423 52 3 429 1 metY O-acetyl-L-homoserine sulfhydrylase Leptospira meyeri
P06106 1.63e-138 406 50 3 435 1 MET17 Homocysteine/cysteine synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q79VI4 1.3e-133 394 48 5 428 1 metY O-acetyl-L-homoserine sulfhydrylase Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
Q5MNH8 4.71e-132 391 45 3 422 2 lolC2 Sulfhydrylase-like protein lolC2 Epichloe uncinata
Q8J0B2 2.13e-124 371 45 3 420 2 lolC1 Sulfhydrylase-like protein lolC1 Epichloe uncinata
P13254 4.98e-109 330 41 3 420 1 mdeA L-methionine gamma-lyase Pseudomonas putida
Q8L0X4 7.65e-105 318 41 5 419 1 mgl L-methionine gamma-lyase Fusobacterium nucleatum subsp. polymorphum
A0A0J6G7P5 2.6e-101 310 39 4 421 3 megL L-methionine gamma-lyase Pseudomonas deceptionensis
Q8RDT4 3.74e-100 306 39 5 419 1 FN1419 L-methionine gamma-lyase Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
Q7MX71 1.3e-97 300 39 5 420 1 mgl L-methionine gamma-lyase Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Q73KL7 5.1e-96 296 39 6 417 1 megL L-methionine gamma-lyase Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
P55218 1.38e-91 285 40 4 420 1 metZ O-succinylhomoserine sulfhydrylase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q5SJ58 4.04e-85 269 39 10 424 1 oah2 O-acetyl-L-homoserine sulfhydrylase 2 Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
P46807 3.04e-82 260 36 5 419 3 metB Cystathionine gamma-synthase Mycobacterium leprae (strain TN)
P9WGB7 2.3e-81 258 37 5 417 1 metB Cystathionine gamma-synthase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGB6 2.3e-81 258 37 5 417 3 metB Cystathionine gamma-synthase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P66876 2.3e-81 258 37 5 417 3 metB Cystathionine gamma-synthase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Q1M0P5 3.46e-80 255 37 6 420 1 metB Cystathionine gamma-synthase Helicobacter pylori
P56069 1.19e-79 253 37 6 420 1 metB Cystathionine gamma-synthase Helicobacter pylori (strain ATCC 700392 / 26695)
O05394 1.25e-79 253 37 7 421 1 mccB Cystathionine gamma-lyase Bacillus subtilis (strain 168)
P9WGB5 1.71e-76 246 34 6 401 1 metZ O-succinylhomoserine sulfhydrylase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGB4 1.71e-76 246 34 6 401 3 metZ O-succinylhomoserine sulfhydrylase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
A2RM21 2.91e-76 245 35 8 420 1 metC Cystathionine beta-lyase Lactococcus lactis subsp. cremoris (strain MG1363)
P0A4K2 2.91e-76 245 35 8 420 3 metC Cystathionine beta-lyase Lactococcus lactis subsp. lactis (strain IL1403)
Q9ZMW7 1.1e-75 243 35 6 420 3 metB Cystathionine gamma-synthase Helicobacter pylori (strain J99 / ATCC 700824)
Q83A83 4.52e-75 242 36 7 419 1 metC Cystathionine beta-lyase Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Q55DV9 1.3e-72 236 33 5 420 1 cysA Cystathionine gamma-lyase Dictyostelium discoideum
P0C2T9 8.05e-71 231 34 9 419 1 metC Cystathionine beta-lyase Lactococcus lactis subsp. cremoris
A0A0M3VI47 1.38e-70 233 35 9 408 1 CBL Cystathionine beta-lyase, chloroplastic Mimosa pudica
Q8VCN5 1.51e-70 231 34 8 421 1 Cth Cystathionine gamma-lyase Mus musculus
Q19QT7 5.05e-70 229 36 9 422 2 CTH Cystathionine gamma-lyase Sus scrofa
P18757 3.81e-69 227 33 7 421 1 Cth Cystathionine gamma-lyase Rattus norvegicus
P55217 2.47e-68 229 34 7 424 1 CGS1 Cystathionine gamma-synthase 1, chloroplastic Arabidopsis thaliana
O31632 5.71e-68 224 34 10 422 1 metC Cystathionine beta-lyase MetC Bacillus subtilis (strain 168)
P53780 2.79e-66 221 33 7 425 1 At3g57050 Cystathionine beta-lyase, chloroplastic Arabidopsis thaliana
P44502 4.94e-66 218 35 9 419 3 metB Cystathionine gamma-synthase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q60HG7 5.59e-66 219 34 8 421 2 CTH Cystathionine gamma-lyase Macaca fascicularis
P0DXC4 2.5e-65 217 32 7 425 1 JFQ02_10020 Canavanine gamma-lyase Pseudomonas canavaninivorans
O31631 4.33e-65 216 34 8 418 1 metI Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase Bacillus subtilis (strain 168)
Q58DW2 6.2e-65 216 35 9 407 2 CTH Cystathionine gamma-lyase Bos taurus
U6BYK3 7.45e-65 217 31 8 420 1 None Mimosinase, chloroplastic Mimosa pudica
A8CEI3 2.07e-63 213 30 9 414 1 None Mimosinase, chloroplastic Leucaena leucocephala
P31373 2.91e-63 211 34 10 425 1 CYS3 Cystathionine gamma-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P0DXD3 2.66e-62 209 32 6 426 1 Rleg2_5066 Canavanine gamma-lyase Rhizobium leguminosarum bv. trifolii (strain WSM2304)
P32929 4.96e-62 209 34 9 425 1 CTH Cystathionine gamma-lyase Homo sapiens
P24601 1.63e-60 202 35 6 356 3 metB Probable cystathionine gamma-synthase (Fragment) Herpetosiphon aurantiacus
P00935 5.56e-59 200 32 5 422 1 metB Cystathionine gamma-synthase Escherichia coli (strain K12)
Q9C876 7.48e-59 201 31 5 407 3 CGS2 Probable cystathionine gamma-synthase 2 Arabidopsis thaliana
P55216 1.52e-56 194 33 10 421 3 cth-2 Putative cystathionine gamma-lyase 2 Caenorhabditis elegans
Q9X0Z7 3.74e-53 184 29 5 408 1 aar L-alanine/L-glutamate racemase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Q1K8G0 6.15e-51 181 30 10 403 1 met-2 Cystathionine beta-lyase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
O94350 1.78e-50 178 30 8 403 3 str3 Cystathionine beta-lyase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q4L332 7.12e-50 176 31 6 374 1 metC Cystathionine beta-lyase MetC Staphylococcus haemolyticus (strain JCSC1435)
Q52811 1.14e-48 173 33 7 372 3 metC Putative cystathionine beta-lyase Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841)
Q826W3 1.12e-44 163 32 11 428 1 mgl L-methionine gamma-lyase Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Q59829 2.61e-37 143 31 9 377 3 cysA Putative cystathionine gamma-lyase Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q07703 4.68e-37 142 28 8 425 1 metC Cystathionine beta-lyase Bordetella avium
Q9SGU9 8.15e-37 142 30 9 363 1 MGL Methionine gamma-lyase Arabidopsis thaliana
Q73GL9 5.22e-35 137 24 9 436 1 aar L-alanine/L-glutamate racemase Wolbachia pipientis wMel
P53101 5.71e-34 135 25 15 443 1 STR3 Cystathionine beta-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P06721 1.06e-29 122 27 12 426 1 metC Cystathionine beta-lyase MetC Escherichia coli (strain K12)
P44527 1.45e-28 119 25 13 424 3 metC Cystathionine beta-lyase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P43623 3.67e-26 111 27 10 353 1 IRC7 Putative cystathionine beta-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P18949 7.17e-24 105 25 13 427 3 metC Cystathionine beta-lyase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P38716 6.33e-22 100 25 14 435 1 YHR112C Uncharacterized trans-sulfuration enzyme YHR112C Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
O42851 1.27e-19 93 26 16 428 1 SPAC23A1.14c Uncharacterized trans-sulfuration enzyme C23A1.14c Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A0A397HQN2 1.24e-13 76 25 14 358 1 ankD Cystathionine gamma-synthase-like protein ankD Aspergillus thermomutatus
P38675 2.26e-12 72 25 9 296 3 met-7 Cystathionine gamma-synthase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
O74314 9.34e-10 64 24 8 270 3 SPBC15D4.09c Probable cystathionine gamma-synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G8XHD7 2.36e-09 62 25 8 284 1 besB L-2-amino-4-chloropent-4-enoate dechlorinase/desaturase Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057)
A4WAM5 1.79e-07 56 27 12 286 3 arnB UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase Enterobacter sp. (strain 638)
Q12198 2.86e-07 56 24 13 309 1 HSU1 Homocysteine/cysteine synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q7NNL4 4.56e-05 48 28 8 189 3 bioF Putative 8-amino-7-oxononanoate synthase Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
A0A2I1D2M7 8.31e-05 48 28 6 182 3 ungC' Alanine racemase ungC' Aspergillus campestris (strain IBT 28561)
A0A2V5GUR2 0.000187 47 32 1 73 1 ungC Alanine racemase ungC Aspergillus violaceofuscus (strain CBS 115571)
P09053 0.00025 47 29 4 106 1 avtA Valine--pyruvate aminotransferase Escherichia coli (strain K12)
A6LAM2 0.000299 46 24 11 227 3 hisC Histidinol-phosphate aminotransferase Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
B5XTK7 0.00035 46 26 13 267 3 arnB UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase Klebsiella pneumoniae (strain 342)
Q749W3 0.00045 45 27 7 183 3 bioF 8-amino-7-oxononanoate synthase Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
C0ZBW6 0.000454 46 38 3 85 3 gcvPA Probable glycine dehydrogenase (decarboxylating) subunit 1 Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)
Q9HY65 0.000744 45 30 6 142 3 arnB UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
B7VBN4 0.000764 45 30 6 142 3 arnB UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase Pseudomonas aeruginosa (strain LESB58)
Q02R23 0.00077 45 30 6 142 3 arnB UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase Pseudomonas aeruginosa (strain UCBPP-PA14)
A6V1P2 0.000895 45 30 6 143 3 arnB UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase Pseudomonas aeruginosa (strain PA7)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS13435
Feature type CDS
Gene -
Product bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
Location 2975825 - 2977099 (strand: -1)
Length 1275 (nucleotides) / 424 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_193
Orthogroup size 9
N. genomes 7

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Genomic region

Domains

PF01053 Cys/Met metabolism PLP-dependent enzyme

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG2873 Amino acid transport and metabolism (E) E O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01740 O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] Cysteine and methionine metabolism
Metabolic pathways		 -

Protein Sequence

MKLETLSVHAGYSPDPTTKAVAVPIYQTTSYAFDDTQHGADLFDLKVPGNIYTRIMNPTNDVLEQRVAALEGGIAAVAVASGMAAITYAIQTIAQVGDNIVSVAKLYGGTYNLMAHTFPRIGIEARFAPHDDLLALEALIDEKTKAVFCESITNPSGNIVDIQALATVAHRHGVPLIVDNTVATPYLCRPFEHGADIIIHSLTKYIGGHGNSIGGIVVDSGKFPWAEHKDRFEILNTPDVSYHGVNYVEHFGAAAYIARCRVAPLRGTGAALSPFNAFLILQGLETLALRMERHTENAQKVAEYLQNHPQVVWVKYAGLTSHPEHNLAVRYMSGKPAGILSFGIKGGAEAGAKFIDALKLIVRLVNIGDAKSLACHPASTTHRQLNDEELERAGVSRDLIRLSIGIEHIDDIIADLEQALNASF

Flanking regions ( +/- flanking 50bp)

TCTAACTTCTATTTAGAAGCTACCTATATGATAAGAACAAAGGGATTGCTATGAAACTTGAGACACTTTCTGTTCACGCTGGTTATTCACCTGATCCAACCACCAAAGCTGTTGCGGTGCCTATTTACCAAACCACCTCTTATGCATTTGATGATACGCAACATGGTGCTGATCTATTTGACTTAAAAGTACCTGGCAATATCTACACGCGTATCATGAACCCAACCAATGATGTATTGGAACAACGCGTTGCCGCCTTAGAAGGAGGGATTGCAGCAGTTGCTGTGGCATCGGGTATGGCTGCGATTACTTATGCTATCCAGACCATTGCACAAGTGGGCGATAACATTGTGTCGGTTGCGAAGCTCTATGGCGGTACATATAACTTAATGGCGCACACTTTTCCCCGTATCGGTATCGAAGCGCGTTTTGCCCCCCATGATGATCTGCTGGCACTTGAAGCGTTAATTGATGAGAAAACCAAAGCGGTATTTTGTGAATCTATCACTAATCCAAGTGGTAATATTGTTGATATTCAAGCTCTCGCCACTGTGGCTCATCGTCATGGTGTCCCTTTAATTGTTGATAATACGGTAGCAACGCCTTACCTATGTCGCCCTTTTGAGCATGGTGCTGATATTATTATTCACTCACTCACTAAATATATTGGTGGTCATGGTAACTCTATTGGTGGGATCGTCGTTGATTCAGGTAAATTTCCTTGGGCTGAACATAAAGATCGTTTTGAAATCCTCAATACACCGGATGTCTCTTATCATGGGGTTAATTATGTTGAACACTTTGGTGCGGCTGCTTATATTGCGCGATGCCGTGTTGCCCCATTGCGTGGAACAGGAGCCGCTCTTTCGCCATTTAACGCCTTCTTAATTCTTCAAGGTCTAGAAACATTAGCGTTACGTATGGAGCGTCATACTGAAAATGCGCAAAAAGTTGCTGAATATTTGCAAAATCATCCTCAAGTTGTCTGGGTTAAATATGCAGGTTTAACCAGCCACCCGGAGCATAATTTAGCGGTACGTTATATGTCAGGTAAACCTGCTGGTATTCTCTCTTTTGGTATCAAAGGCGGTGCCGAAGCGGGTGCGAAATTTATCGATGCATTGAAATTGATTGTGCGTCTTGTCAATATTGGTGATGCTAAATCTTTGGCTTGTCATCCTGCATCAACCACTCATCGCCAACTCAATGATGAAGAGTTAGAACGCGCGGGGGTTTCTCGTGATTTAATTCGACTTTCAATTGGTATTGAACATATAGACGATATTATCGCTGATCTAGAACAAGCATTAAACGCCAGTTTTTAACCGTTATTAATAATAGTTAATTAATAACGATTAAGTAATAGTAATTTAAT