Homologs in group_1556

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_10080 FBDBKF_10080 81.9 Morganella morganii S1 mrdA peptidoglycan DD-transpeptidase MrdA
EHELCC_04880 EHELCC_04880 81.9 Morganella morganii S2 mrdA peptidoglycan DD-transpeptidase MrdA
NLDBIP_04880 NLDBIP_04880 81.9 Morganella morganii S4 mrdA peptidoglycan DD-transpeptidase MrdA
LHKJJB_13750 LHKJJB_13750 81.9 Morganella morganii S3 mrdA peptidoglycan DD-transpeptidase MrdA
HKOGLL_12785 HKOGLL_12785 81.9 Morganella morganii S5 mrdA peptidoglycan DD-transpeptidase MrdA
F4V73_RS00255 F4V73_RS00255 80.5 Morganella psychrotolerans mrdA peptidoglycan DD-transpeptidase MrdA

Distribution of the homologs in the orthogroup group_1556

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1556

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0AD65 0.0 998 75 1 626 1 mrdA Peptidoglycan D,D-transpeptidase MrdA Escherichia coli (strain K12)
P0AD66 0.0 998 75 1 626 3 mrdA Peptidoglycan D,D-transpeptidase MrdA Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P0AD67 0.0 998 75 1 626 3 mrdA Peptidoglycan D,D-transpeptidase MrdA Escherichia coli O157:H7
P44469 0.0 721 57 6 620 3 mrdA Peptidoglycan D,D-transpeptidase MrdA Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P0CL14 0.0 710 57 3 621 3 mrdA Peptidoglycan D,D-transpeptidase MrdA Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
E1WGF1 0.0 710 57 3 621 3 mrdA Peptidoglycan D,D-transpeptidase MrdA Salmonella typhimurium (strain SL1344)
Q03524 1.83e-49 186 27 24 623 1 spoVD Stage V sporulation protein D Bacillus subtilis (strain 168)
P42971 3.51e-46 177 26 20 561 1 pbpC Penicillin-binding protein 3 Bacillus subtilis (strain 168)
G3XD46 2.27e-40 159 25 19 618 1 ftsI Peptidoglycan D,D-transpeptidase FtsI Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P54488 1.32e-34 143 26 15 524 1 pbpA Penicillin-binding protein 2A Bacillus subtilis (strain 168)
P07944 3.88e-34 141 28 14 449 2 pbp Beta-lactam-inducible penicillin-binding protein Staphylococcus aureus
Q89AQ0 9.2e-33 136 25 21 564 3 ftsI Peptidoglycan D,D-transpeptidase FtsI Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Q07868 6.36e-31 132 24 21 573 1 pbpB Penicillin-binding protein 2B Bacillus subtilis (strain 168)
P0AD68 1.64e-30 130 24 22 650 1 ftsI Peptidoglycan D,D-transpeptidase FtsI Escherichia coli (strain K12)
P0AD69 1.64e-30 130 24 22 650 3 ftsI Peptidoglycan D,D-transpeptidase FtsI Escherichia coli O157:H7
P0A0U9 3.77e-29 125 25 22 620 3 penA Probable peptidoglycan D,D-transpeptidase PenA Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
P0A0U8 3.77e-29 125 25 22 620 3 penA Probable peptidoglycan D,D-transpeptidase PenA Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)
P08149 7.91e-29 125 25 22 620 1 penA Probable peptidoglycan D,D-transpeptidase PenA Neisseria gonorrhoeae
O85297 2.46e-28 123 22 20 629 3 ftsI Peptidoglycan D,D-transpeptidase FtsI Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Q9I1K1 2.75e-27 120 23 23 623 1 pbpC Probable peptidoglycan D,D-transpeptidase PbpC Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P57317 3.32e-27 120 22 20 624 3 ftsI Peptidoglycan D,D-transpeptidase FtsI Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
P45059 1.51e-24 112 25 15 464 1 ftsI Peptidoglycan D,D-transpeptidase FtsI Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
A0R022 3.38e-24 111 23 27 678 1 pbpB Penicillin-binding protein PbpB Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
Q9MUV9 5.02e-23 107 23 20 558 3 ftsI Peptidoglycan D,D-transpeptidase FtsI homolog Mesostigma viride
A0QNG3 6.42e-21 100 27 12 344 3 pbpA Peptidoglycan D,D-transpeptidase PbpA Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
L0T911 1.06e-19 97 23 17 518 1 pbpB Penicillin-binding protein PbpB Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WKD1 1.7e-19 95 27 12 366 1 pbpA Peptidoglycan D,D-transpeptidase PbpA Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WKD0 1.7e-19 95 27 12 366 3 pbpA Peptidoglycan D,D-transpeptidase PbpA Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P0A3M6 7.89e-18 91 24 23 514 1 penA Penicillin-binding protein 2B Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
P0A3M5 7.89e-18 91 24 23 514 3 penA Penicillin-binding protein 2B Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
A0A0H2ZQ75 7.89e-18 91 24 23 514 3 penA Penicillin-binding protein 2B Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
A2CI41 1.13e-17 90 23 17 498 3 ftsI Peptidoglycan D,D-transpeptidase FtsI homolog Chlorokybus atmophyticus
P14677 2.47e-16 86 21 19 586 1 pbpX Penicillin-binding protein 2x Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
P59676 2.81e-16 86 21 19 586 1 pbpX Penicillin-binding protein 2X Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
P16873 3.98e-14 78 25 19 442 3 penA Probable peptidoglycan D,D-transpeptidase PenA (Fragment) Neisseria flavescens
B8H0A0 2.66e-13 76 24 15 426 1 ftsI Probable peptidoglycan D,D-transpeptidase FtsI Caulobacter vibrioides (strain NA1000 / CB15N)
Q796K8 1.11e-12 74 24 13 439 1 pbpH Penicillin-binding protein H Bacillus subtilis (strain 168)
Q9TL36 1.61e-11 71 22 21 522 3 ftsI Peptidoglycan D,D-transpeptidase FtsI homolog Nephroselmis olivacea
O32032 1.73e-10 67 23 27 558 2 pbpI Penicillin-binding protein 4B Bacillus subtilis (strain 168)
Q9KNU5 1.31e-05 52 23 7 245 3 mrcA Penicillin-binding protein 1A Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
O87626 5.84e-05 50 26 5 150 3 mrcA Penicillin-binding protein 1A Neisseria flavescens
O86088 0.00013 48 22 12 297 3 mrcA Penicillin-binding protein 1A Neisseria cinerea
P31776 0.000206 48 22 7 225 1 mrcA Penicillin-binding protein 1A Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
O87579 0.000271 47 25 5 155 3 mrcA Penicillin-binding protein 1A Neisseria lactamica
P02918 0.000303 47 23 3 146 1 mrcA Penicillin-binding protein 1A Escherichia coli (strain K12)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS02100
Feature type CDS
Gene mrdA
Product peptidoglycan DD-transpeptidase MrdA
Location 493408 - 495303 (strand: -1)
Length 1896 (nucleotides) / 631 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_1556
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00905 Penicillin binding protein transpeptidase domain
PF03717 Penicillin-binding Protein dimerisation domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0768 Cell cycle control, cell division, chromosome partitioning (D)
Cell wall/membrane/envelope biogenesis (M)		 DM Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2)

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K05515 penicillin-binding protein 2 [EC:3.4.16.4] Peptidoglycan biosynthesis
Metabolic pathways
beta-Lactam resistance		 -

Protein Sequence

MKKRKRTPFRDYTAESKLFIRRVIVAFSGILVLTGILVFNLYHLQVARHDDYQTRSNDNRIKLVPIPPSRGIIYDRNGVPLALNRTIYQLEIVPEKVANIQETLESLREVVDLTDDDIAAFEKERKRSRRFSSIPLKTSLDQVQVARFAINQYRYPGLEIKGYQRRYYPYGSALTHVIGYVAKINDKDVERLEKEGLYPNYAATRDIGKLGIERYYESVLHGKTGYEEVEVNSRGRVIRQLHEQPPQAGKDIYLTIDLELQTYIETLLTTSRAAVVVTDPRNGEILALVSNPSYDPNLFVGGISNTDYQGLLNNPDRPLINRATQGLYPPASTVKPFMSVAALSEGVITPNTTIHDPGWWQLPGSEKRYRDWKRWGHGKLNVTKSIIESADTFFYQVAYDMGIDRISTWMSRFGYGEYTGIDLSEERNGIMPTREWKQQRYKKPWYQGDTIPVGIGQGYWTATPIQMSKALMTLINDGQVKTPHLLYGTKLGNEMLPYVDKETRQIGDINSGYWELAKYGMYGVANLPNGTGRRSFADAPYKIAAKSGTAQVFSYETYNASQLAEHLRDHKLMIAFAPYENPTVAVSIILENGGAGPSVGDITRQILDHIILGDNNTELPISPPSPRGSEE

Flanking regions ( +/- flanking 50bp)

TCATCGGGAATAATAAATTGGCGGGTAAGTAAGTGAAATCAACTAATGGGATGAAGAAAAGAAAACGCACCCCGTTTCGAGATTATACAGCGGAGTCAAAACTCTTTATCCGCCGTGTTATTGTCGCATTTTCAGGGATCTTAGTTTTAACGGGCATCTTAGTTTTTAACTTGTATCACTTACAAGTCGCTCGCCACGATGATTATCAAACTCGCTCGAATGATAACCGGATCAAATTAGTTCCCATCCCACCGAGCCGAGGCATTATTTACGATCGTAATGGGGTTCCACTTGCCCTAAATCGTACTATCTATCAATTAGAAATCGTACCGGAGAAAGTGGCTAATATCCAAGAAACATTGGAGAGTTTACGAGAGGTCGTTGATTTAACTGACGACGATATTGCTGCATTTGAAAAAGAGCGAAAACGCTCTCGTCGTTTTAGTTCTATTCCGCTTAAAACGTCACTTGACCAAGTGCAAGTGGCACGTTTTGCCATTAATCAATATCGCTATCCCGGATTAGAAATCAAAGGCTATCAACGTCGCTATTACCCTTATGGTTCAGCCCTTACTCATGTTATTGGTTATGTTGCAAAAATTAACGATAAAGATGTAGAACGTCTTGAAAAAGAAGGGCTCTATCCTAATTACGCAGCAACCCGAGATATCGGTAAATTAGGTATTGAACGCTATTATGAATCTGTTTTGCATGGTAAAACCGGTTATGAAGAGGTCGAAGTTAATAGCCGTGGCCGTGTGATCCGCCAATTGCATGAGCAACCACCACAAGCCGGTAAAGATATCTACCTAACTATCGATCTTGAATTACAAACCTATATTGAAACGCTATTAACCACTAGCCGAGCGGCTGTGGTCGTCACAGATCCTCGTAACGGCGAGATATTAGCACTGGTTTCTAATCCAAGTTATGACCCTAACCTATTTGTTGGGGGAATATCTAATACAGACTATCAAGGCCTACTTAATAATCCTGATAGACCATTAATAAACCGGGCAACCCAAGGGCTCTATCCTCCTGCATCAACGGTTAAACCCTTTATGTCTGTTGCAGCCCTAAGTGAAGGGGTTATTACTCCTAACACAACTATCCATGATCCGGGCTGGTGGCAACTGCCCGGCTCTGAAAAACGCTATCGTGACTGGAAACGTTGGGGTCATGGAAAACTCAATGTTACTAAATCCATTATTGAGTCAGCAGATACCTTCTTCTATCAAGTTGCCTATGATATGGGTATTGATCGTATTTCCACATGGATGTCCCGCTTTGGCTATGGTGAATACACGGGGATTGACCTTTCTGAAGAGCGTAATGGCATTATGCCAACCCGAGAATGGAAACAACAACGATATAAAAAACCTTGGTATCAAGGGGATACCATCCCTGTTGGTATAGGTCAAGGTTACTGGACGGCGACCCCAATCCAAATGTCAAAAGCGTTAATGACCTTAATTAACGATGGTCAGGTTAAAACCCCTCACTTACTTTATGGCACCAAGTTAGGTAATGAAATGCTACCTTACGTGGATAAAGAGACACGCCAAATTGGCGATATCAACTCCGGTTATTGGGAGTTAGCGAAGTACGGTATGTATGGTGTTGCCAATCTACCCAATGGTACAGGGCGACGTAGCTTTGCTGATGCTCCTTATAAGATTGCTGCAAAATCAGGTACAGCACAGGTATTTAGTTATGAAACCTATAATGCTAGCCAATTAGCAGAACATCTTCGTGATCATAAATTAATGATTGCTTTTGCGCCTTATGAAAACCCTACCGTTGCCGTCTCTATAATTTTAGAAAATGGTGGTGCTGGCCCATCTGTTGGGGATATTACTCGCCAAATACTTGATCACATTATACTTGGAGACAACAACACCGAGTTGCCTATTTCCCCGCCTTCACCGCGTGGCTCAGAGGAATAACCCAATGACAGAAAATAACAAGAAAAAATCACTCTGGACGCGTTTACATA