Homologs in group_975

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_05390 FBDBKF_05390 100.0 Morganella morganii S1 xthA exodeoxyribonuclease III
EHELCC_12200 EHELCC_12200 100.0 Morganella morganii S2 xthA exodeoxyribonuclease III
NLDBIP_12540 NLDBIP_12540 100.0 Morganella morganii S4 xthA exodeoxyribonuclease III
HKOGLL_11015 HKOGLL_11015 100.0 Morganella morganii S5 xthA exodeoxyribonuclease III
F4V73_RS05845 F4V73_RS05845 91.4 Morganella psychrotolerans xthA exodeoxyribonuclease III
PMI_RS07245 PMI_RS07245 76.4 Proteus mirabilis HI4320 xthA exodeoxyribonuclease III

Distribution of the homologs in the orthogroup group_975

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_975

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P09030 8.52e-156 437 75 1 266 1 xthA Exodeoxyribonuclease III Escherichia coli (strain K12)
P0A1A9 6.32e-154 432 74 1 266 3 xthA Exodeoxyribonuclease III Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P0A1B0 6.32e-154 432 74 1 266 3 xthA Exodeoxyribonuclease III Salmonella typhi
P44318 4.08e-142 402 70 1 266 3 xthA Exodeoxyribonuclease III Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P37454 3.29e-35 129 31 8 265 1 exoA Exodeoxyribonuclease Bacillus subtilis (strain 168)
O26314 7.13e-34 126 31 10 272 1 MTH_212 DNA uridine endonuclease Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
A0MTA1 8.08e-33 125 31 9 267 1 apex1 DNA repair nuclease APEX1 Danio rerio
A1YES6 2.23e-27 110 27 9 268 3 APEX1 DNA repair nuclease/redox regulator APEX1 Gorilla gorilla gorilla
P23196 6.14e-27 109 27 9 268 1 APEX1 DNA repair nuclease/redox regulator APEX1 Bos taurus
A2T6Y4 9.19e-27 108 27 9 268 3 APEX1 DNA repair nuclease/redox regulator APEX1 Pan troglodytes
A1YFZ3 9.19e-27 108 27 9 268 3 APEX1 DNA repair nuclease/redox regulator APEX1 Pan paniscus
P27695 1.21e-26 108 27 9 268 1 APEX1 DNA repair nuclease/redox regulator APEX1 Homo sapiens
P27864 2.06e-26 111 30 7 270 1 Rrp1 Recombination repair protein 1 Drosophila melanogaster
A2T7I6 1.25e-25 105 27 10 268 3 APEX1 DNA repair nuclease/redox regulator APEX1 Pongo pygmaeus
P28352 5.87e-25 104 26 9 268 1 Apex1 DNA repair nuclease/redox regulator APEX1 Mus musculus
P51173 1.39e-24 103 28 7 270 2 apeA DNA-(apurinic or apyrimidinic site) endonuclease Dictyostelium discoideum
P43138 1.54e-24 103 26 9 268 1 Apex1 DNA repair nuclease/redox regulator APEX1 Rattus norvegicus
P45951 6.62e-19 89 28 14 273 1 ARP DNA-(apurinic or apyrimidinic site) endonuclease, chloroplastic Arabidopsis thaliana
P0A2X4 3.16e-17 82 27 13 300 3 exoA Exodeoxyribonuclease Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
P0A2X3 3.16e-17 82 27 13 300 3 exoA Exodeoxyribonuclease Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Q6DDT4 3.18e-12 69 25 12 312 1 apex2.L DNA-(apurinic or apyrimidinic site) endonuclease 2 Xenopus laevis
Q68G58 2.42e-10 63 27 16 328 1 Apex2 DNA-(apurinic or apyrimidinic site) endonuclease 2 Mus musculus
Q9UBZ4 2.45e-10 63 26 16 333 1 APEX2 DNA-(apurinic or apyrimidinic site) endonuclease 2 Homo sapiens
Q5E9N9 3.04e-10 63 25 16 332 2 APEX2 DNA-(apurinic or apyrimidinic site) endonuclease 2 Bos taurus
F4JNY0 4.78e-09 60 24 10 289 1 APE2 DNA-(apurinic or apyrimidinic site) endonuclease 2 Arabidopsis thaliana

  • Number of RefSeq hits:

General

Source Morganella morganii S3
Locus tag LHKJJB_12400
Feature type CDS
Gene xthA
Product exodeoxyribonuclease III
Location 94335 - 95144 (strand: -1)
Length 810 (nucleotides) / 269 (amino acids)

Contig

Accession ZDB_369
Length 181491 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_975
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF03372 Endonuclease/Exonuclease/phosphatase family

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0708 Replication, recombination and repair (L) L Exonuclease III

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01142 exodeoxyribonuclease III [EC:3.1.11.2] Base excision repair -

Protein Sequence

MKFVSFNINGLRARPHQLEAIIAQHQPDVIGLQETKVHDEMFPLDDLKHLGYHIFYHGQKSHYGVALLTKAEPVAVRKGFAGDDEDAQRRLIMADIDTPAGVLTVINGYFPQGESRDHPLKFPAKTKFYQDLQDYLSGRSNQDPIVIMGDMNISPQDIDIGIGDANRKRWLKTGKCSFLPEEREWMDRLLSWGLTDTYRAMYPDADDRFSWFDYRSRGFDDNRGLRIDLILASNSLAPRCTATGIDYEIRGMEKPSDHAPIWAEFDLTR

Flanking regions ( +/- flanking 50bp)

CTGCGATCTGTTACTCTTTTGTTGTTAACTCATCAACCGGTTGGAATTCTATGAAGTTTGTCTCTTTTAACATTAACGGGTTAAGAGCCCGGCCTCACCAGCTGGAAGCGATTATCGCACAGCATCAGCCTGATGTTATCGGCCTCCAGGAAACCAAAGTCCATGACGAGATGTTCCCGCTCGATGACCTGAAACACCTCGGCTACCACATTTTTTATCACGGCCAGAAATCCCATTACGGTGTCGCCCTGCTGACCAAAGCAGAGCCGGTTGCCGTGCGCAAAGGCTTCGCAGGAGATGATGAAGATGCCCAGCGCCGTCTGATTATGGCGGATATTGATACCCCGGCCGGGGTACTGACAGTGATTAATGGTTATTTCCCCCAGGGAGAGAGCCGCGACCACCCGCTGAAATTCCCGGCGAAAACCAAGTTCTATCAGGATTTACAGGACTATCTGTCCGGGCGCTCCAACCAGGATCCGATTGTTATTATGGGTGATATGAATATCAGCCCGCAGGATATTGATATCGGAATTGGTGACGCCAACCGCAAACGCTGGCTGAAGACCGGCAAATGCTCTTTCCTGCCGGAAGAGCGCGAGTGGATGGATCGCCTGCTCAGCTGGGGACTGACTGACACTTACCGCGCGATGTATCCGGATGCAGACGACCGTTTCTCGTGGTTCGATTACCGTTCACGCGGCTTTGATGACAACCGGGGACTGCGGATTGACCTGATTCTGGCAAGCAACTCGCTGGCACCACGCTGTACCGCCACCGGCATTGATTATGAAATCCGTGGTATGGAAAAACCCTCTGACCACGCGCCAATCTGGGCTGAATTTGATTTAACCCGCTGATAAAAAAATGTCCCGCAGTGCGGGACATTTTTTATTCTTCTTCCTGTAGC