Homologs in group_262

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7 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_04725 FBDBKF_04725 100.0 Morganella morganii S1 pDC1 TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase
EHELCC_06015 EHELCC_06015 100.0 Morganella morganii S2 pDC1 TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase
NLDBIP_06335 NLDBIP_06335 100.0 Morganella morganii S4 pDC1 TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase
LHKJJB_03215 LHKJJB_03215 100.0 Morganella morganii S3 pDC1 TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase
F4V73_RS09200 F4V73_RS09200 80.9 Morganella psychrotolerans - thiamine pyrophosphate-binding protein
PMI_RS01075 PMI_RS01075 32.8 Proteus mirabilis HI4320 - thiamine pyrophosphate-binding protein
PMI_RS04150 PMI_RS04150 67.2 Proteus mirabilis HI4320 - thiamine pyrophosphate-binding protein

Distribution of the homologs in the orthogroup group_262

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_262

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q09737 5.28e-116 358 36 10 542 3 SPAC13A11.06 Putative pyruvate decarboxylase C13A11.06 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P23234 6.71e-115 354 37 4 528 1 ipdC Indole-3-pyruvate decarboxylase Enterobacter cloacae
Q9CBD6 1.66e-114 354 37 7 534 3 kdc Alpha-keto-acid decarboxylase Mycobacterium leprae (strain TN)
A0QBE6 1.93e-112 348 36 7 542 3 kdc Alpha-keto-acid decarboxylase Mycobacterium avium (strain 104)
Q742Q2 5.35e-112 347 36 7 552 3 kdc Alpha-keto-acid decarboxylase Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
O42873 1.16e-111 347 37 11 540 3 SPAC3G9.11c Putative pyruvate decarboxylase C3G9.11c Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P06169 6.22e-110 342 37 9 538 1 PDC1 Pyruvate decarboxylase isozyme 1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P34734 1.85e-109 341 37 7 511 3 PDC Pyruvate decarboxylase Hanseniaspora uvarum
P26263 6.81e-109 339 37 8 525 1 PDC6 Pyruvate decarboxylase isozyme 3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q2UKV4 7.88e-109 339 38 10 526 3 pdcA Pyruvate decarboxylase Aspergillus oryzae (strain ATCC 42149 / RIB 40)
P9WG37 2.47e-108 338 35 7 549 1 kdc Alpha-keto-acid decarboxylase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
A5U0P1 2.47e-108 338 35 7 549 3 kdc Alpha-keto-acid decarboxylase Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
A1KGY5 2.47e-108 338 35 7 549 3 kdc Alpha-keto-acid decarboxylase Mycobacterium bovis (strain BCG / Pasteur 1173P2)
Q7U140 2.47e-108 338 35 7 549 3 kdc Alpha-keto-acid decarboxylase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P16467 1.21e-107 336 37 8 553 1 PDC5 Pyruvate decarboxylase isozyme 2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P9WG36 1.3e-107 336 35 7 549 3 kdc Alpha-keto-acid decarboxylase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P83779 7.59e-107 334 36 10 537 1 PDC11 Pyruvate decarboxylase Candida albicans (strain SC5314 / ATCC MYA-2876)
A0PL16 7.62e-107 334 35 5 548 3 kdc Alpha-keto-acid decarboxylase Mycobacterium ulcerans (strain Agy99)
Q6FJA3 5.17e-106 332 37 8 522 1 PDC1 Pyruvate decarboxylase Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
P33149 3.71e-105 330 36 9 548 3 PDC1 Pyruvate decarboxylase Kluyveromyces marxianus
Q12629 1.15e-104 328 36 9 553 1 PDC1 Pyruvate decarboxylase Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Q07471 1.24e-104 330 33 7 543 1 THI3 Thiamine metabolism regulatory protein THI3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A0R480 1.71e-104 328 37 6 552 3 kdc Alpha-keto-acid decarboxylase Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
Q0CNV1 3.6e-104 327 38 11 519 3 pdcA Pyruvate decarboxylase Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Q4WXX9 1e-103 326 38 10 525 3 pdcA Pyruvate decarboxylase Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)
P87208 9.05e-103 323 38 11 527 3 pdcA Pyruvate decarboxylase Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
P51844 3.41e-79 262 31 14 574 3 pdcA Pyruvate decarboxylase Aspergillus parasiticus
Q9M040 1.41e-78 261 33 10 553 2 PDC4 Pyruvate decarboxylase 4 Arabidopsis thaliana
A2XFI3 8.1e-78 259 32 14 565 2 PDC2 Pyruvate decarboxylase 2 Oryza sativa subsp. indica
Q0DHF6 2.02e-77 258 33 13 557 2 PDC1 Pyruvate decarboxylase 1 Oryza sativa subsp. japonica
O82647 2.8e-77 258 32 10 553 2 PDC1 Pyruvate decarboxylase 1 Arabidopsis thaliana
Q10MW3 7.48e-77 257 32 14 564 2 PDC2 Pyruvate decarboxylase 2 Oryza sativa subsp. japonica
A2Y5L9 9.04e-77 256 33 13 557 2 PDC1 Pyruvate decarboxylase 1 Oryza sativa subsp. indica
P06672 3.11e-76 254 32 7 563 1 pdc Pyruvate decarboxylase Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
P51846 9.38e-76 254 31 12 582 2 PDC2 Pyruvate decarboxylase 2 Nicotiana tabacum
Q9M039 1.57e-75 253 32 11 557 2 PDC3 Pyruvate decarboxylase 3 Arabidopsis thaliana
Q9FFT4 2.76e-75 253 32 13 557 2 PDC2 Pyruvate decarboxylase 2 Arabidopsis thaliana
Q9P7P6 2.89e-75 252 30 8 530 3 SPAC186.09 Probable pyruvate decarboxylase C186.09 Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q92345 2.96e-75 252 33 7 524 1 SPAC1F8.07c Probable pyruvate decarboxylase C1F8.07c Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P51850 1.15e-73 248 32 10 558 2 PDC1 Pyruvate decarboxylase 1 Pisum sativum
P28516 7.69e-73 246 32 11 553 2 PDC1 Pyruvate decarboxylase 1 Zea mays
A2YQ76 1.58e-71 242 32 16 563 3 PDC3 Pyruvate decarboxylase 3 Oryza sativa subsp. indica
Q0D3D2 1.94e-71 242 32 16 563 2 PDC3 Pyruvate decarboxylase 3 Oryza sativa subsp. japonica
Q06408 6.31e-67 231 28 16 594 1 ARO10 Transaminated amino acid decarboxylase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P33287 1.09e-61 216 30 10 525 1 cfp Pyruvate decarboxylase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
P51845 1.72e-52 187 32 8 427 2 PDC1 Pyruvate decarboxylase 1 (Fragment) Nicotiana tabacum
P51852 1.73e-41 160 27 18 564 1 ipdC Indole-3-pyruvate decarboxylase Azospirillum brasilense
P51851 1.33e-35 140 31 7 322 2 PDC2 Pyruvate decarboxylase 2 (Fragment) Pisum sativum
P0DUV9 5.11e-19 94 24 20 572 1 None 2-hydroxyacyl-CoA lyase Actinomycetospora chiangmaiensis (strain DSM 45062 / JCM 15998 / CCTCC AA 205017 / NBRC 104400 / YIM 0006)
Q05327 2.6e-18 87 32 4 183 2 PDC3 Pyruvate decarboxylase 3 (Fragment) Zea mays
Q57725 4.91e-17 87 24 21 561 3 ilvB Probable acetolactate synthase large subunit Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
O78518 9.77e-17 87 23 13 482 3 ilvB Acetolactate synthase large subunit Guillardia theta
P0A623 1.74e-16 86 23 20 536 3 ilvB Acetolactate synthase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P9WG41 1.74e-16 86 23 20 536 1 ilvB1 Acetolactate synthase large subunit IlvB1 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WG40 1.74e-16 86 23 20 536 3 ilvB1 Acetolactate synthase large subunit IlvB1 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
A3SR25 8.46e-16 84 22 20 569 1 xsc Sulfoacetaldehyde acetyltransferase Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM)
P0DP90 3.77e-15 82 24 16 475 1 ilvG Acetolactate synthase isozyme 2 large subunit Escherichia coli (strain K12)
Q84H41 2.09e-14 79 23 20 568 1 xsc Sulfoacetaldehyde acetyltransferase Alcaligenes xylosoxydans xylosoxydans
Q59498 2.66e-14 79 23 19 565 3 ilvB Acetolactate synthase Mycobacterium avium
P45261 2.96e-14 79 22 19 558 3 ilvI Acetolactate synthase large subunit Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q9RQ65 3.77e-14 79 23 17 491 3 ilvI Acetolactate synthase large subunit Buchnera aphidicola subsp. Schlechtendalia chinensis
D5AKX8 4.51e-14 78 22 23 601 2 xsc Sulfoacetaldehyde acetyltransferase Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
O08353 6.44e-14 78 22 19 549 3 ilvB Probable acetolactate synthase large subunit Methanococcus aeolicus
P69684 4.93e-13 75 22 14 482 3 ilvB Acetolactate synthase large subunit Porphyra umbilicalis
P69683 4.93e-13 75 22 14 482 3 ilvB Acetolactate synthase large subunit Porphyra purpurea
Q02137 7.01e-13 74 23 16 483 3 ilvB Acetolactate synthase large subunit Lactococcus lactis subsp. lactis (strain IL1403)
P14874 8.4e-13 74 22 15 473 3 None Acetolactate synthase 2, chloroplastic Brassica napus
P27819 1.18e-12 74 22 17 537 3 None Acetolactate synthase 3, chloroplastic Brassica napus
Q89AP7 1.57e-12 73 22 13 484 3 ilvI Acetolactate synthase large subunit Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
P09342 2.35e-12 73 22 15 479 1 ALS Acetolactate synthase 1, chloroplastic Nicotiana tabacum SURA
Q7U5G1 2.48e-12 73 23 15 475 3 ilvB Acetolactate synthase large subunit Parasynechococcus marenigrum (strain WH8102)
P17597 2.49e-12 73 23 17 484 1 ALS Acetolactate synthase, chloroplastic Arabidopsis thaliana
P27818 2.62e-12 73 22 17 537 3 None Acetolactate synthase 1, chloroplastic Brassica napus
P42463 2.81e-12 73 23 19 560 3 ilvB Acetolactate synthase large subunit Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
Q84H44 9.85e-12 71 21 16 561 1 xsc Sulfoacetaldehyde acetyltransferase Castellaniella defragrans
P09114 1.13e-11 71 22 15 479 1 ALS Acetolactate synthase 2, chloroplastic Nicotiana tabacum SURB
O06335 1.22e-11 70 24 20 500 2 ilvB2 Putative acetolactate synthase large subunit IlvB2 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
O85293 1.31e-11 70 23 16 489 3 ilvI Acetolactate synthase large subunit Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Q1XDF6 1.48e-11 70 21 13 480 3 ilvB Acetolactate synthase large subunit Neopyropia yezoensis
Q92UW6 3.55e-11 69 21 24 594 3 xsc Probable sulfoacetaldehyde acetyltransferase Rhizobium meliloti (strain 1021)
P08142 6.54e-11 68 23 14 476 1 ilvB Acetolactate synthase isozyme 1 large subunit Escherichia coli (strain K12)
O33112 8.56e-11 68 22 19 535 3 ilvB Acetolactate synthase Mycobacterium leprae (strain TN)
P00893 1.39e-10 67 22 13 490 1 ilvI Acetolactate synthase isozyme 3 large subunit Escherichia coli (strain K12)
P37251 1.64e-10 67 21 17 482 1 ilvB Acetolactate synthase large subunit Bacillus subtilis (strain 168)
P27868 1.72e-10 67 21 14 506 3 ilvY Acetolactate synthase (Fragment) Arthrospira platensis
P40811 2.62e-10 66 23 14 484 3 ilvI Acetolactate synthase isozyme 3 large subunit Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q41768 4.19e-10 66 22 17 493 3 ALS1 Acetolactate synthase 1, chloroplastic Zea mays
P07342 1.65e-09 64 21 22 570 1 ILV2 Acetolactate synthase catalytic subunit, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
O19929 1.86e-09 63 22 9 344 3 ilvB Acetolactate synthase large subunit Cyanidium caldarium
P0AEP7 3.36e-09 63 22 17 488 1 gcl Glyoxylate carboligase Escherichia coli (strain K12)
P0AEP8 3.36e-09 63 22 17 488 3 gcl Glyoxylate carboligase Escherichia coli O157:H7
P0CH62 4.04e-09 62 21 19 553 1 None Cyclohexane-1,2-dione hydrolase Azoarcus sp.
Q9HUR2 8.37e-09 61 22 20 534 3 mdlC Benzoylformate decarboxylase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9LF46 1.13e-08 61 21 28 593 1 HACL 2-hydroxyacyl-CoA lyase Arabidopsis thaliana
Q6K2E8 1.87e-08 60 21 13 480 2 ALS1 Acetolactate synthase 1, chloroplastic Oryza sativa subsp. japonica
P07003 1.96e-08 60 21 17 557 1 poxB Pyruvate dehydrogenase [ubiquinone] Escherichia coli (strain K12)
A0A2I2F2I5 2.46e-08 60 22 26 582 3 cfoL Acetolactate synthase catalytic subunit, mitochondrial Aspergillus candidus
P96591 3.43e-08 60 20 18 553 2 ydaP Putative thiamine pyrophosphate-containing protein YdaP Bacillus subtilis (strain 168)
Q6SSJ3 9.06e-08 58 20 23 579 3 ILV2 Acetolactate synthase, mitochondrial Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
Q5KPJ5 1.07e-07 58 20 23 579 3 ILV2 Acetolactate synthase, mitochondrial Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Q6NV04 3.2e-07 57 21 18 512 2 ilvbl 2-hydroxyacyl-CoA lyase 2 Danio rerio
P36620 3.65e-07 56 21 16 505 3 ilv1 Acetolactate synthase, mitochondrial Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q0JMH0 3.88e-07 56 26 4 169 3 Os01g0505400 2-hydroxyacyl-CoA lyase Oryza sativa subsp. japonica
P20906 6.92e-07 55 22 3 198 1 mdlC Benzoylformate decarboxylase Pseudomonas putida
P0DP89 1.32e-06 54 23 12 345 5 ilvG Putative acetolactate synthase isozyme 2 large subunit Escherichia coli (strain K12)
P57321 7.41e-06 52 45 0 55 3 ilvI Acetolactate synthase large subunit Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
P57321 0.000251 47 34 1 100 3 ilvI Acetolactate synthase large subunit Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Q04789 1.18e-05 52 20 19 577 2 alsS Acetolactate synthase Bacillus subtilis (strain 168)
O53554 1.78e-05 51 31 7 194 1 ilvX Putative acetolactate synthase large subunit IlvX Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Q41769 4.47e-05 50 21 16 489 3 ALS2 Acetolactate synthase 2, chloroplastic Zea mays
O61856 5.41e-05 49 24 6 187 3 T26C12.1 2-hydroxyacyl-CoA lyase 2 Caenorhabditis elegans
Q9HUI8 0.000127 48 29 3 135 1 aruI Probable 2-ketoarginine decarboxylase AruI Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9LCV9 0.000393 47 28 4 147 1 ceaS N(2)-(2-carboxyethyl)arginine synthase Streptomyces clavuligerus
P37063 0.000486 46 22 14 400 1 pox5 Pyruvate oxidase Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)

  • Number of RefSeq hits:

General

Source Morganella morganii S5
Locus tag HKOGLL_06690
Feature type CDS
Gene pDC1
Product TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase
Location 147589 - 149238 (strand: 1)
Length 1650 (nucleotides) / 549 (amino acids)

Contig

Accession ZDB_683
Length 224720 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_262
Orthogroup size 8
N. genomes 7

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Genomic region

Domains

PF00205 Thiamine pyrophosphate enzyme, central domain
PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG3961 Carbohydrate transport and metabolism (G)
Coenzyme transport and metabolism (H)
General function prediction only (R)		 GHR TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K04103 indolepyruvate decarboxylase [EC:4.1.1.74] Tryptophan metabolism
Metabolic pathways		 -

Protein Sequence

MTKSVIEHVLSRLADLGITDVFGVAGDFAFPIEDAVCDGNTQRWIGNCNELNAAYAADGYARIKGAAALSTTFGVGELSAINGIAGSYAENLPVFHLVGMPASGVQKSGRLVHHTLGDGNFSLFCELGQRLSCAHAIMTPENCVAETERLIAAALRERRPVYMGFPFDYATQPVQIPEHLTAPAQPVSDKTALTEAVAAIRAKLADSPSACILPGMLAARSGLIDDVQVLIRQTGLPYATMFMDKAIISESDPHYAGMYNGQLMNPQVREFVENSDCVLGIGAVMTDFNTGSFTADIAPEKLISIMADHVRVGTKTWHNVYMRDLLPALAAGLSHRECHIPAATGLGKPVADASGNITPSYLYPRFEQLFRKDDIIIAETGTVSMGLGFALLPEGAQFHNQTLWGSIGWATPAAVGAAIAAPDRRVILITGEGSHQLTVQEISQFGRFGLKPLIFVLNNDGYLIERLLCKDPEAVYNDLPQWRYAQLPQALGCDNWYCRRVTTCTELDEAIREAETGDRAAYIEIITERYAASDLAKKLGESVATLYSF

Flanking regions ( +/- flanking 50bp)

CATAACACGTGGTTCGTTCTGAATAAACGGTGTGATCGGAGAAGATAACAATGACAAAAAGCGTAATTGAGCATGTTTTAAGCCGTTTGGCAGATTTGGGCATCACCGATGTTTTCGGTGTCGCGGGAGATTTTGCGTTCCCCATTGAAGATGCGGTCTGCGACGGTAACACACAACGCTGGATTGGTAACTGTAACGAACTGAACGCCGCCTATGCCGCAGATGGCTACGCGCGGATCAAGGGTGCCGCGGCGCTTTCCACCACATTCGGCGTGGGTGAATTAAGCGCGATCAACGGTATTGCCGGATCCTATGCAGAAAATCTGCCGGTTTTTCATCTGGTCGGCATGCCTGCCAGTGGTGTACAAAAGAGTGGCCGTCTGGTGCATCACACCCTGGGCGATGGTAATTTCAGCCTGTTCTGTGAACTGGGGCAGCGCCTTTCCTGTGCCCACGCCATAATGACCCCGGAGAACTGTGTGGCGGAGACAGAACGCCTGATTGCTGCCGCGCTGCGCGAGCGCCGTCCGGTCTATATGGGTTTCCCGTTTGATTACGCCACACAGCCGGTTCAGATACCGGAACACCTTACCGCACCGGCACAACCGGTCAGTGACAAAACCGCGCTCACTGAAGCGGTTGCCGCGATCAGGGCAAAACTGGCGGACAGCCCGTCTGCCTGTATCCTGCCGGGCATGCTGGCCGCACGTTCCGGACTGATTGATGACGTACAGGTGCTTATCCGTCAGACCGGGCTGCCGTACGCCACCATGTTTATGGATAAAGCCATCATCAGTGAATCCGACCCGCATTACGCCGGGATGTATAACGGTCAGCTGATGAATCCGCAGGTCAGGGAATTTGTTGAAAACAGTGACTGTGTGCTGGGTATCGGAGCGGTGATGACAGACTTTAACACCGGCAGTTTTACCGCTGATATCGCCCCGGAAAAACTGATCAGTATTATGGCGGATCATGTCCGGGTTGGCACAAAAACCTGGCATAATGTGTATATGCGGGATCTGCTGCCTGCCCTGGCCGCCGGACTTTCGCACAGAGAATGTCATATTCCGGCAGCAACCGGGCTGGGTAAACCGGTGGCTGACGCTTCCGGTAATATTACCCCGTCGTATCTGTATCCCCGTTTTGAACAATTGTTCAGAAAAGACGACATTATCATCGCCGAAACCGGCACCGTTTCTATGGGGCTCGGCTTTGCGCTGCTGCCGGAAGGGGCGCAATTCCATAACCAGACGTTATGGGGATCAATCGGCTGGGCAACACCTGCGGCCGTTGGAGCCGCCATCGCGGCGCCTGATCGCAGAGTGATTCTGATCACCGGGGAAGGCTCACACCAGCTGACCGTCCAGGAAATCAGCCAGTTTGGCCGTTTTGGTCTGAAACCACTTATTTTCGTGCTGAATAATGACGGCTATCTCATTGAGCGCCTGCTGTGCAAAGACCCGGAAGCCGTTTATAACGACCTGCCGCAGTGGCGTTACGCACAACTGCCGCAGGCGCTGGGATGCGATAACTGGTATTGCCGCCGCGTCACCACCTGCACGGAGCTGGATGAGGCAATCCGGGAAGCGGAAACCGGTGACCGCGCCGCCTATATTGAAATCATTACGGAGCGCTATGCCGCATCCGATCTGGCAAAAAAACTCGGTGAATCAGTAGCAACACTGTACTCGTTTTAACTCTCCGGTGATCCGGATGCAGCCCCCGCGGCATCCGGATATTAAAACCC