Homologs in group_1380

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
EHELCC_12995 EHELCC_12995 100.0 Morganella morganii S2 tlyC Hemolysin-related protein, contains CBS domains, UPF0053 family
NLDBIP_13335 NLDBIP_13335 100.0 Morganella morganii S4 tlyC Hemolysin-related protein, contains CBS domains, UPF0053 family
LHKJJB_13220 LHKJJB_13220 100.0 Morganella morganii S3 tlyC Hemolysin-related protein, contains CBS domains, UPF0053 family
HKOGLL_11810 HKOGLL_11810 100.0 Morganella morganii S5 tlyC Hemolysin-related protein, contains CBS domains, UPF0053 family
F4V73_RS09755 F4V73_RS09755 91.6 Morganella psychrotolerans - hemolysin family protein
PMI_RS16865 PMI_RS16865 78.8 Proteus mirabilis HI4320 - hemolysin family protein

Distribution of the homologs in the orthogroup group_1380

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_1380

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
A0A0F6BAS6 0.0 669 70 1 448 3 paeA Polyamine export protein Salmonella typhimurium (strain 14028s / SGSC 2262)
P0AE45 0.0 665 70 0 445 1 paeA Polyamine export protein Escherichia coli (strain K12)
P0AE46 0.0 665 70 0 445 3 paeA Polyamine export protein Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P0AE47 0.0 665 70 0 445 3 paeA Polyamine export protein Escherichia coli O157:H7
P44717 1.91e-156 453 50 3 432 3 paeA Polyamine export protein Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P74409 3.76e-71 234 31 7 433 3 sll0260 UPF0053 protein sll0260 Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
P54428 6.38e-38 146 22 8 433 3 yrkA UPF0053 protein YrkA Bacillus subtilis (strain 168)
O05241 8.43e-37 143 22 6 423 3 yugS UPF0053 protein YugS Bacillus subtilis (strain 168)
O07589 1.22e-33 135 22 7 430 3 yhdT UPF0053 protein YhdT Bacillus subtilis (strain 168)
P76389 2.61e-33 135 35 6 236 3 yegH UPF0053 protein YegH Escherichia coli (strain K12)
Q83KI8 2.66e-33 135 35 6 236 3 yegH UPF0053 protein YegH Shigella flexneri
Q84R21 8.98e-32 131 25 6 405 2 CBSDUFCH2 DUF21 domain-containing protein At1g55930, chloroplastic Arabidopsis thaliana
O07585 1.93e-31 128 21 7 446 3 yhdP UPF0053 protein YhdP Bacillus subtilis (strain 168)
P37908 6.6e-31 126 23 14 438 1 yfjD UPF0053 inner membrane protein YfjD Escherichia coli (strain K12)
Q9LK65 1.43e-29 125 26 7 359 4 CBSDUFCH1 Putative DUF21 domain-containing protein At3g13070, chloroplastic Arabidopsis thaliana
Q8K9M0 3.65e-28 120 26 2 254 3 BUsg_314 UPF0053 protein BUsg_314 Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
P0AEC0 4.08e-28 120 28 3 240 1 yoaE UPF0053 inner membrane protein YoaE Escherichia coli (strain K12)
P0AEC1 4.08e-28 120 28 3 240 3 yoaE UPF0053 inner membrane protein YoaE Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P0AEC2 4.08e-28 120 28 3 240 3 yoaE UPF0053 inner membrane protein YoaE Escherichia coli O157:H7
P54505 2.53e-27 117 21 9 413 3 yqhB UPF0053 protein YqhB Bacillus subtilis (strain 168)
P57408 1.28e-26 115 28 4 237 3 BU323 UPF0053 protein BU323 Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Q57017 1.92e-26 114 21 12 435 1 HI_0107 UPF0053 protein HI_0107 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q48445 3.02e-25 108 35 7 208 3 None UPF0053 protein in cps region (Fragment) Klebsiella pneumoniae
Q89AI6 4.44e-25 111 27 3 232 3 bbp_300 UPF0053 protein bbp_300 Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
P9WLQ6 4.7e-24 105 24 5 329 3 MT1889 Uncharacterized protein MT1889 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P9WLQ7 5.83e-24 105 24 5 329 1 Rv1841c Uncharacterized protein Rv1841c Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P74078 2.46e-23 103 27 4 252 3 sll1254 UPF0053 protein sll1254 Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q54318 4.49e-20 93 26 3 220 3 tlyC Hemolysin C Brachyspira hyodysenteriae
P9WFP2 5.76e-20 95 22 8 437 3 MT1890 UPF0053 protein MT1890 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P9WFP3 6.26e-20 95 22 8 437 1 Rv1842c UPF0053 protein Rv1842c Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P67131 3.37e-18 90 24 7 308 3 BQ2027_MB2387C UPF0053 protein Mb2387c Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P9WFP1 3.37e-18 90 24 7 308 1 Rv2366c UPF0053 protein Rv2366c Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WFP0 3.37e-18 90 24 7 308 3 MT2435 UPF0053 protein MT2435 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Q9KTE3 4.55e-17 84 25 7 279 3 corC Magnesium and cobalt efflux protein CorC Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q89AC1 1.52e-16 83 21 4 268 3 corC Magnesium and cobalt efflux protein CorC Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Q9CM13 1.59e-16 83 25 5 270 3 corC Magnesium and cobalt efflux protein CorC Pasteurella multocida (strain Pm70)
Q1RGX2 1.77e-16 83 24 8 281 3 tlyC Possible hemolysin C Rickettsia bellii (strain RML369-C)
P0A2L3 4.86e-16 81 24 6 281 1 corC Magnesium and cobalt efflux protein CorC Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P0A2L4 4.86e-16 81 24 6 281 3 corC Magnesium and cobalt efflux protein CorC Salmonella typhi
P0AE81 1.16e-15 80 23 6 281 3 corC Magnesium and cobalt efflux protein CorC Shigella flexneri
P0AE78 1.16e-15 80 23 6 281 1 corC Magnesium and cobalt efflux protein CorC Escherichia coli (strain K12)
P0AE79 1.16e-15 80 23 6 281 3 corC Magnesium and cobalt efflux protein CorC Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P0AE80 1.16e-15 80 23 6 281 3 corC Magnesium and cobalt efflux protein CorC Escherichia coli O157:H7
Q57368 2.04e-15 80 23 7 276 3 corC Magnesium and cobalt efflux protein CorC Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
A8GUH1 1.84e-14 77 23 8 285 3 tlyC Possible hemolysin C Rickettsia bellii (strain OSU 85-389)
Q4UK99 2.63e-14 76 25 8 252 3 tlyC Hemolysin C Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
A8F2M1 3e-14 76 25 8 252 3 tlyC Hemolysin C homolog Rickettsia massiliae (strain Mtu5)
A8GPR9 4.75e-14 76 25 8 252 3 tlyC Possible hemolysin C Rickettsia akari (strain Hartford)
P57518 8.2e-14 75 22 7 277 3 corC Magnesium and cobalt efflux protein CorC Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
A8GTI4 1.76e-13 74 24 8 252 3 tlyC Hemolysin C homolog Rickettsia rickettsii (strain Sheila Smith)
Q92GI2 2e-13 74 24 8 252 3 tlyC Hemolysin C homolog Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Q68W10 2.64e-13 73 23 6 247 1 tlyC Hemolysin C Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Q8K9C0 2.81e-13 73 20 5 278 3 corC Magnesium and cobalt efflux protein CorC Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
P75586 1.58e-12 72 21 5 258 3 MPN_159 UPF0053 protein MG146 homolog Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)
Q49399 5.55e-12 70 19 7 357 3 MG146 UPF0053 protein MG146 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
O05961 9.88e-12 69 24 6 229 2 tlyC Hemolysin C Rickettsia prowazekii (strain Madrid E)
A8EZU0 1.6e-10 65 23 9 269 3 tlyC Possible hemolysin C Rickettsia canadensis (strain McKiel)

  • Number of RefSeq hits:

General

Source Morganella morganii S1
Locus tag FBDBKF_08530
Feature type CDS
Gene tlyC
Product Hemolysin-related protein, contains CBS domains, UPF0053 family
Location 85520 - 86890 (strand: -1)
Length 1371 (nucleotides) / 456 (amino acids)

Contig

Accession contig_9
Length 163724 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_1380
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF01595 Cyclin M transmembrane N-terminal domain
PF03471 Transporter associated domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG1253 General function prediction only (R) R Hemolysin-related protein, contains CBS domains, UPF0053 family

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K03699 magnesium and cobalt exporter, CNNM family - -

Virulence factor Annotation(s)

VF gene ID Protein VF ID Category
VFG038900 Hemolysin A VF0646 Exotoxin

Protein Sequence

MLNSLLIVLLLCAISAFFSLSEISLAASRRIKLKVMIDEGNTNAAHVLRLQEAPGMFFTVVQIGLNAVAILAGIVGESAFSPALRTLFGNFMADAAAQQLGSVLSFIIVTSMFILLADLTPKRLGMIKPEAVAIRIVQPMRFCLTVLRPLAWLFNGLSNLFFKLFKIPLARNEDITSDDIYAVVEAGAVAGVLRKQEHELIENVFELESRTVPSAMTSRESVVYFDKQENEESIKEKISTQPHSKFLVCDGGLDHVLGYVDSKDLLNRVLNGQSLNLHEGVQIRPALMIPDTLSLSDTLESFKNAGEDFAIILNEYAMVMGVITINDVMITLMGDLVGQGQEEQIVARDENSWLIEGGTPIEDVQRVLDIDEFPDDSNYETIAGFLMYKLRRIPKRTDSVKFSGFKFEVVDIDNYKIDQLLVTRIPDAPVVPRPSAAESGKKGQSDVAHNEQHQKP

Flanking regions ( +/- flanking 50bp)

ATCAACAACAGCGCGCCCAGAGGCAATCGTGCCGGCCATTCGGAACTTATATGTTAAATAGTTTATTAATCGTCCTGTTACTGTGCGCGATCAGCGCATTCTTTTCGTTATCTGAAATATCACTGGCCGCCTCGCGGCGTATCAAACTCAAAGTCATGATTGACGAAGGCAATACCAATGCCGCCCATGTGCTCCGTTTGCAGGAAGCACCGGGGATGTTCTTCACCGTGGTGCAAATCGGCCTGAACGCCGTGGCGATCCTCGCCGGTATTGTCGGTGAATCGGCCTTTTCACCGGCGCTGCGCACCCTGTTCGGCAATTTTATGGCCGATGCCGCCGCACAGCAGCTCGGCTCAGTATTGTCATTTATTATCGTGACCTCCATGTTTATCCTGCTGGCGGATCTGACCCCGAAACGTCTCGGGATGATCAAACCGGAAGCGGTCGCCATCCGGATTGTCCAGCCGATGCGTTTTTGCCTGACAGTACTGCGCCCGCTGGCCTGGCTGTTTAACGGATTATCCAACCTGTTCTTTAAATTATTCAAAATCCCGCTGGCGCGAAATGAAGATATCACTTCTGATGATATTTACGCGGTGGTGGAAGCAGGTGCGGTCGCCGGTGTGCTGCGCAAGCAGGAGCACGAACTGATCGAAAACGTGTTTGAGCTGGAATCCCGTACTGTGCCGTCTGCTATGACCTCCCGTGAGAGCGTGGTCTATTTCGACAAGCAGGAAAACGAAGAGAGCATCAAAGAGAAGATCTCCACACAGCCGCACTCAAAATTCCTGGTGTGCGACGGCGGTCTGGATCATGTGCTCGGTTATGTCGATTCCAAAGATCTGCTCAACCGCGTGCTGAACGGCCAGAGCCTGAATCTGCATGAAGGTGTGCAAATCCGCCCGGCACTGATGATCCCGGATACCCTGAGCCTGTCAGACACCCTGGAGAGCTTTAAAAATGCCGGGGAAGACTTCGCAATCATTCTGAATGAATACGCCATGGTGATGGGTGTTATCACTATCAATGACGTGATGATTACCCTGATGGGAGATCTGGTCGGTCAGGGGCAGGAAGAGCAGATTGTCGCCCGTGATGAAAATTCCTGGCTGATTGAAGGCGGTACACCGATTGAGGATGTGCAGCGGGTGCTGGATATTGATGAGTTCCCGGATGACAGCAACTACGAAACCATCGCCGGCTTCCTGATGTATAAGCTGCGCCGTATCCCGAAACGGACCGATTCCGTGAAATTCTCGGGCTTTAAGTTTGAAGTGGTGGATATCGACAACTACAAGATTGACCAGCTGCTGGTTACACGGATCCCGGATGCACCGGTTGTCCCGCGTCCGTCAGCGGCGGAAAGCGGCAAAAAGGGTCAGTCTGACGTGGCACACAACGAACAGCACCAGAAACCGTAAAACTAACCCTTCTTCATCAGACAGGTATTGTGGTTACGCCAGCTGCGCCT