Homologs in group_92

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11 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_09245 FBDBKF_09245 48.3 Morganella morganii S1 metC Cystathionine beta-lyase/cystathionine gamma-synthase
FBDBKF_10625 FBDBKF_10625 95.0 Morganella morganii S1 megL methionine gamma-lyase
EHELCC_10165 EHELCC_10165 48.3 Morganella morganii S2 metC Cystathionine beta-lyase/cystathionine gamma-synthase
EHELCC_14960 EHELCC_14960 95.0 Morganella morganii S2 megL methionine gamma-lyase
NLDBIP_10510 NLDBIP_10510 48.3 Morganella morganii S4 metC Cystathionine beta-lyase/cystathionine gamma-synthase
NLDBIP_14790 NLDBIP_14790 95.0 Morganella morganii S4 megL methionine gamma-lyase
LHKJJB_10845 LHKJJB_10845 48.3 Morganella morganii S3 metC Cystathionine beta-lyase/cystathionine gamma-synthase
LHKJJB_14555 LHKJJB_14555 95.0 Morganella morganii S3 megL methionine gamma-lyase
HKOGLL_13175 HKOGLL_13175 95.0 Morganella morganii S5 megL methionine gamma-lyase
HKOGLL_13905 HKOGLL_13905 48.3 Morganella morganii S5 metC Cystathionine beta-lyase/cystathionine gamma-synthase
F4V73_RS10725 F4V73_RS10725 47.5 Morganella psychrotolerans - PLP-dependent aspartate aminotransferase family protein

Distribution of the homologs in the orthogroup group_92

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_92

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q8L0X4 1.56e-178 505 60 2 389 1 mgl L-methionine gamma-lyase Fusobacterium nucleatum subsp. polymorphum
Q73KL7 1.23e-176 500 59 2 392 1 megL L-methionine gamma-lyase Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
Q8RDT4 7.94e-174 493 58 2 394 1 FN1419 L-methionine gamma-lyase Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
Q7MX71 1.28e-173 493 59 2 392 1 mgl L-methionine gamma-lyase Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
P13254 5.99e-145 420 51 1 391 1 mdeA L-methionine gamma-lyase Pseudomonas putida
A0A0J6G7P5 3.37e-139 405 50 3 400 3 megL L-methionine gamma-lyase Pseudomonas deceptionensis
Q83A83 2.01e-124 367 47 3 385 1 metC Cystathionine beta-lyase Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Q55DV9 6.35e-120 356 46 4 392 1 cysA Cystathionine gamma-lyase Dictyostelium discoideum
O05394 6.68e-120 355 48 4 383 1 mccB Cystathionine gamma-lyase Bacillus subtilis (strain 168)
P56069 1e-115 345 46 4 385 1 metB Cystathionine gamma-synthase Helicobacter pylori (strain ATCC 700392 / 26695)
Q1M0P5 1.15e-115 345 46 4 385 1 metB Cystathionine gamma-synthase Helicobacter pylori
Q9WZY4 1.41e-115 346 43 6 428 1 TM_0882 O-acetyl-L-homoserine sulfhydrylase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
P55218 6.01e-113 338 44 2 392 1 metZ O-succinylhomoserine sulfhydrylase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9ZMW7 2.38e-112 336 45 4 385 3 metB Cystathionine gamma-synthase Helicobacter pylori (strain J99 / ATCC 700824)
Q60HG7 1.92e-111 335 44 5 389 2 CTH Cystathionine gamma-lyase Macaca fascicularis
A2RM21 2e-111 334 45 5 386 1 metC Cystathionine beta-lyase Lactococcus lactis subsp. cremoris (strain MG1363)
P0A4K2 2e-111 334 45 5 386 3 metC Cystathionine beta-lyase Lactococcus lactis subsp. lactis (strain IL1403)
Q8VCN5 1.35e-110 332 44 5 394 1 Cth Cystathionine gamma-lyase Mus musculus
P9WGB7 9.44e-110 330 43 5 387 1 metB Cystathionine gamma-synthase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGB6 9.44e-110 330 43 5 387 3 metB Cystathionine gamma-synthase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P66876 9.44e-110 330 43 5 387 3 metB Cystathionine gamma-synthase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
O31632 1.38e-109 330 42 4 390 1 metC Cystathionine beta-lyase MetC Bacillus subtilis (strain 168)
P0C2T9 6e-109 328 45 5 386 1 metC Cystathionine beta-lyase Lactococcus lactis subsp. cremoris
P94890 6.05e-109 330 42 6 428 1 metY O-acetyl-L-homoserine sulfhydrylase Leptospira meyeri
P18757 9.69e-109 328 43 5 394 1 Cth Cystathionine gamma-lyase Rattus norvegicus
Q19QT7 1.66e-108 327 44 5 390 2 CTH Cystathionine gamma-lyase Sus scrofa
P55216 3.22e-105 318 44 6 393 3 cth-2 Putative cystathionine gamma-lyase 2 Caenorhabditis elegans
Q58DW2 3.8e-103 314 44 6 372 2 CTH Cystathionine gamma-lyase Bos taurus
Q5SK88 1.21e-102 313 40 5 420 1 oah1 O-acetyl-L-homoserine sulfhydrylase 1 Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
S0DUX5 1.38e-102 313 41 5 425 1 FUB7 Sulfhydrylase FUB7 Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831)
A0A0D2YG02 2.1e-102 313 43 4 425 1 FUB7 Sulfhydrylase FUB7 Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)
P46807 2.58e-102 311 41 4 386 3 metB Cystathionine gamma-synthase Mycobacterium leprae (strain TN)
W7MS09 2.84e-102 312 41 5 425 1 FUB7 Sulfhydrylase FUB7 Gibberella moniliformis (strain M3125 / FGSC 7600)
O13326 1.04e-101 311 42 4 420 1 met17 Homocysteine synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P24601 3.3e-101 306 46 4 328 3 metB Probable cystathionine gamma-synthase (Fragment) Herpetosiphon aurantiacus
P32929 5.11e-100 306 44 6 390 1 CTH Cystathionine gamma-lyase Homo sapiens
Q79VI4 1.86e-99 305 40 7 434 1 metY O-acetyl-L-homoserine sulfhydrylase Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
P55217 8.67e-99 308 40 3 383 1 CGS1 Cystathionine gamma-synthase 1, chloroplastic Arabidopsis thaliana
P50125 4.1e-98 302 41 4 429 1 cysD Homocysteine synthase Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
P9WGB5 4.24e-97 298 39 2 368 1 metZ O-succinylhomoserine sulfhydrylase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGB4 4.24e-97 298 39 2 368 3 metZ O-succinylhomoserine sulfhydrylase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P31373 7.98e-93 287 42 9 395 1 CYS3 Cystathionine gamma-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P53780 1.3e-90 283 39 5 383 1 At3g57050 Cystathionine beta-lyase, chloroplastic Arabidopsis thaliana
Q5MNH8 1.58e-90 283 38 6 419 2 lolC2 Sulfhydrylase-like protein lolC2 Epichloe uncinata
Q92441 3.79e-90 281 38 7 433 3 MET17 Homocysteine/cysteine synthase Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Q9C876 5.72e-88 275 38 3 376 3 CGS2 Probable cystathionine gamma-synthase 2 Arabidopsis thaliana
P00935 4.17e-87 272 40 4 387 1 metB Cystathionine gamma-synthase Escherichia coli (strain K12)
O31631 4.57e-87 271 37 5 386 1 metI Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase Bacillus subtilis (strain 168)
A0A0M3VI47 1.52e-86 273 38 5 387 1 CBL Cystathionine beta-lyase, chloroplastic Mimosa pudica
P44502 1.98e-86 270 40 8 387 3 metB Cystathionine gamma-synthase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P0DXD3 2.07e-86 271 37 6 396 1 Rleg2_5066 Canavanine gamma-lyase Rhizobium leguminosarum bv. trifolii (strain WSM2304)
P0DXC4 4.56e-86 270 37 6 389 1 JFQ02_10020 Canavanine gamma-lyase Pseudomonas canavaninivorans
Q4L332 6.22e-85 266 40 6 367 1 metC Cystathionine beta-lyase MetC Staphylococcus haemolyticus (strain JCSC1435)
Q8J0B2 1.92e-84 268 38 6 425 2 lolC1 Sulfhydrylase-like protein lolC1 Epichloe uncinata
P06106 5.45e-84 266 37 7 438 1 MET17 Homocysteine/cysteine synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q9X0Z7 1.15e-82 260 38 6 387 1 aar L-alanine/L-glutamate racemase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
A8CEI3 2.51e-82 261 39 6 375 1 None Mimosinase, chloroplastic Leucaena leucocephala
Q5SJ58 1.88e-81 258 38 10 414 1 oah2 O-acetyl-L-homoserine sulfhydrylase 2 Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
U6BYK3 1.43e-77 249 36 6 385 1 None Mimosinase, chloroplastic Mimosa pudica
Q826W3 2.38e-77 248 40 11 397 1 mgl L-methionine gamma-lyase Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Q1K8G0 3.11e-74 241 37 6 376 1 met-2 Cystathionine beta-lyase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
O94350 4.07e-72 233 35 9 391 3 str3 Cystathionine beta-lyase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q07703 6.93e-71 231 33 7 404 1 metC Cystathionine beta-lyase Bordetella avium
Q52811 4.05e-65 216 32 7 399 3 metC Putative cystathionine beta-lyase Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841)
Q59829 1.17e-60 204 37 7 342 3 cysA Putative cystathionine gamma-lyase Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q9SGU9 8.26e-59 200 37 10 361 1 MGL Methionine gamma-lyase Arabidopsis thaliana
Q73GL9 1.59e-58 199 30 7 401 1 aar L-alanine/L-glutamate racemase Wolbachia pipientis wMel
P06721 9.22e-54 186 31 8 404 1 metC Cystathionine beta-lyase MetC Escherichia coli (strain K12)
P44527 1.5e-52 183 29 7 396 3 metC Cystathionine beta-lyase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P18949 1.38e-51 180 30 8 404 3 metC Cystathionine beta-lyase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P53101 8.39e-51 180 31 12 414 1 STR3 Cystathionine beta-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P43623 3.78e-41 151 28 4 341 1 IRC7 Putative cystathionine beta-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P38716 2.71e-31 125 27 15 402 1 YHR112C Uncharacterized trans-sulfuration enzyme YHR112C Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
O42851 8.15e-27 113 28 14 404 1 SPAC23A1.14c Uncharacterized trans-sulfuration enzyme C23A1.14c Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P38675 5.98e-13 73 28 6 246 3 met-7 Cystathionine gamma-synthase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
P47164 6.5e-12 70 27 10 262 1 STR2 Cystathionine gamma-synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
O74314 9.6e-12 70 25 9 310 3 SPBC15D4.09c Probable cystathionine gamma-synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A0A0C2WKN7 6.15e-11 67 23 8 293 2 iboG1 Cystathionine gamma-synthase-like enzyme iboG1 Amanita muscaria (strain Koide BX008)
A0A397HQN2 7.71e-10 64 22 11 353 1 ankD Cystathionine gamma-synthase-like protein ankD Aspergillus thermomutatus
Q04533 3.55e-09 62 25 18 412 1 YML082W Putative cystathionine gamma-synthase YML082W Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
G8XHD7 8.13e-09 60 25 8 244 1 besB L-2-amino-4-chloropent-4-enoate dechlorinase/desaturase Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057)
Q12198 8.47e-09 60 25 15 357 1 HSU1 Homocysteine/cysteine synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A0A2I1D2M7 1.47e-06 53 22 11 285 3 ungC' Alanine racemase ungC' Aspergillus campestris (strain IBT 28561)
A0A2V5GUR2 2.54e-05 50 23 9 277 1 ungC Alanine racemase ungC Aspergillus violaceofuscus (strain CBS 115571)

  • Number of RefSeq hits:

General

Source Morganella psychrotolerans
Locus tag F4V73_RS14335
Feature type CDS
Gene megL
Product methionine gamma-lyase
Location 89915 - 91111 (strand: -1)
Length 1197 (nucleotides) / 398 (amino acids)

Contig

Accession term accessions NZ_VXKB01000004 accessions NZ_VXKB01000000 Name: value, dtype: object
Length 258164 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_92
Orthogroup size 12
N. genomes 6

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Genomic region

Domains

PF01053 Cys/Met metabolism PLP-dependent enzyme

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0626 Amino acid transport and metabolism (E) E Cystathionine beta-lyase/cystathionine gamma-synthase

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K01761 methionine-gamma-lyase [EC:4.4.1.11] Cysteine and methionine metabolism
Selenocompound metabolism
Metabolic pathways		 -

Protein Sequence

MHDYSNKGYDTKIVHAGQQPDPLTGALSTPIYQTSTFVFDSAEQGAARFALEEEGYIYSRLGNPTNAALEEKMRVLENGEAALVTASGISAISTTILTMCGQGDHIVASDTLYGCTYALLSHSLPKFGIEVTFVRADNPENIKAAMKPNTKMVYVETPANPTLAMIDLEAAANVAHEGGAMLVVDNTFMSPYCQRPLELGADIVVHSVTKYINGHGDVIGGVIVGPADFLVPARLVGVKDITGGVMSPFNAWLTLRGLKTLHVRMERHCSNAMKVAEYLETNPNITSVFYPGLPSHPQHELAKKQMSGFGGMISFEIKGGIEAGRKVMNSVELCLLAVSLGDTETLIQHPASMTHSPIPAEERLKAGITDGLIRISVGLETAEDIIADLEQAIAKAVA

Flanking regions ( +/- flanking 50bp)

ACTGCAACAACACATGTTGGCAAAATAAAAAATTTTATCCTGGAGGATATATGCACGATTATTCGAATAAAGGTTATGACACTAAGATTGTTCACGCTGGTCAGCAACCTGATCCACTGACAGGTGCGTTATCAACCCCAATCTATCAGACCTCTACATTCGTTTTTGACAGCGCAGAGCAAGGGGCAGCACGTTTCGCATTAGAAGAAGAAGGTTATATCTACTCCCGTTTAGGTAACCCGACTAACGCAGCATTAGAAGAAAAAATGCGTGTTCTGGAAAACGGCGAAGCCGCTCTGGTAACAGCATCCGGTATCTCTGCAATCTCCACCACTATTCTGACCATGTGCGGTCAGGGCGACCACATCGTTGCTTCTGACACTCTGTATGGTTGTACTTATGCACTGCTGTCTCACTCTCTGCCTAAGTTCGGTATCGAAGTAACATTCGTTCGTGCTGATAATCCGGAAAACATCAAAGCAGCAATGAAACCAAACACCAAAATGGTGTATGTCGAAACGCCTGCTAACCCGACTCTGGCAATGATCGACCTCGAAGCTGCTGCAAATGTTGCTCACGAAGGCGGCGCTATGCTGGTTGTGGATAACACCTTTATGTCTCCGTACTGCCAGCGTCCGCTGGAATTAGGTGCAGACATCGTGGTTCACAGTGTCACTAAATACATCAATGGTCACGGCGACGTTATCGGTGGTGTGATTGTCGGTCCTGCTGACTTCCTGGTTCCTGCCCGTCTGGTGGGTGTTAAAGACATCACCGGTGGCGTCATGAGCCCGTTCAACGCATGGTTAACTCTGCGTGGTCTGAAAACGCTGCATGTGCGCATGGAACGTCACTGCTCTAACGCAATGAAAGTTGCTGAATACTTAGAAACTAACCCGAACATCACATCTGTATTCTATCCGGGCCTCCCATCTCACCCGCAGCACGAATTAGCGAAAAAACAGATGAGCGGCTTCGGCGGTATGATCAGCTTTGAAATCAAAGGTGGTATTGAAGCCGGCCGTAAAGTAATGAATTCCGTTGAATTATGTCTGCTGGCAGTAAGCCTCGGCGATACTGAAACCCTGATCCAACACCCTGCTTCAATGACTCACTCACCGATCCCGGCTGAAGAGCGTCTGAAAGCAGGTATCACTGACGGCCTGATTCGTATCTCCGTCGGTCTGGAAACAGCTGAAGACATCATTGCCGACCTGGAACAAGCCATCGCGAAAGCGGTTGCTTAAGACCTGAGTGAAAAATTAAGTCATCAGTAATGTACTCACCCCGTCGTGTT