Homologs in group_3778

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1 homologs were identified in 1 genome with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_20230 FBDBKF_20230 100.0 Morganella morganii S1 blaTEM-1 broad-spectrum class A beta-lactamase TEM-1

Distribution of the homologs in the orthogroup group_3778

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_3778

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P62594 0.0 591 100 0 286 3 bla Beta-lactamase TEM Salmonella typhi
P62593 0.0 591 100 0 286 1 bla Beta-lactamase TEM Escherichia coli
Q48406 0.0 588 99 0 286 1 blaT-12b Beta-lactamase TEM-12 Klebsiella oxytoca
P0AD64 5.88e-137 391 65 0 284 1 bla Beta-lactamase SHV-1 Klebsiella pneumoniae
P0AD63 5.88e-137 391 65 0 284 1 bla Beta-lactamase SHV-1 Escherichia coli
Q9S424 1.13e-136 390 65 0 284 3 bla Beta-lactamase SHV-13 Klebsiella pneumoniae
P0AA00 1.19e-136 390 65 0 284 3 bla Beta-lactamase SHV-2 Salmonella typhimurium
P0A9Z8 1.19e-136 390 65 0 284 3 bla Beta-lactamase SHV-2 Klebsiella pneumoniae
O08337 2.91e-136 389 65 0 284 3 bla Beta-lactamase SHV-8 Escherichia coli
P0A9Z9 5.08e-136 388 65 0 284 3 bla Beta-lactamase SHV-2 Klebsiella pneumoniae subsp. ozaenae
P0A9Z7 5.08e-136 388 65 0 284 1 bla Beta-lactamase SHV-2 Escherichia coli
Q9S169 9.8e-136 388 65 0 284 1 bla Beta-lactamase SHV-24 Escherichia coli
Q9AHN9 1.01e-135 387 64 0 284 3 bla Beta-lactamase SHV-29 Klebsiella pneumoniae
P30896 1.12e-135 387 65 0 284 1 bla Beta-lactamase SHV-3 Klebsiella pneumoniae
P0A3M2 1.91e-135 387 64 0 284 3 bla Beta-lactamase SHV-5 Pseudomonas aeruginosa
P0A3M1 1.91e-135 387 64 0 284 3 bla Beta-lactamase SHV-5 Klebsiella pneumoniae
Q93LM8 6.88e-135 385 64 0 284 3 bla Beta-lactamase SHV-34 Escherichia coli
Q848S4 9.65e-135 385 64 0 284 3 bla Beta-lactamase SHV-46 Klebsiella oxytoca
P05192 7.18e-131 375 63 0 277 3 None Beta-lactamase Klebsiella pneumoniae
P37323 2.15e-130 373 67 0 262 1 bla Beta-lactamase SHV-4 Klebsiella pneumoniae
P18251 1.53e-125 362 61 0 284 3 None Beta-lactamase Ohio-1 Enterobacter cloacae
P96348 7.89e-125 359 66 0 260 3 bla Beta-lactamase SHV-6 (Fragment) Klebsiella pneumoniae
P30897 1.15e-88 269 47 2 280 1 blaP Beta-lactamase Proteus mirabilis
Q44056 8.74e-76 236 45 4 279 3 aer1 Beta-lactamase AER-1 Aeromonas hydrophila
P37322 1.86e-68 217 43 3 281 3 carB3 Beta-lactamase CARB-3 Pseudomonas aeruginosa
P16897 1.97e-68 217 42 3 281 1 pse4 Beta-lactamase PSE-4 Pseudomonas aeruginosa
P81781 3.38e-68 216 42 3 284 1 carB6 Beta-lactamase CARB-6 Vibrio cholerae
Q03170 5.1e-68 216 42 3 281 1 pse1 Beta-lactamase PSE-1 Pseudomonas aeruginosa
Q9EZQ7 6.47e-67 214 46 1 243 1 bla Beta-lactamase AST-1 Nocardia asteroides
P14171 1.11e-63 205 42 3 264 3 None Beta-lactamase Rhodobacter capsulatus
Q5YXD6 2.36e-62 202 46 1 211 1 bla Beta-lactamase FAR-1 Nocardia farcinica (strain IFM 10152)
Q01166 3.27e-62 201 39 4 269 1 blaA Beta-lactamase Yersinia enterocolitica
Q51355 5.18e-62 200 41 3 270 3 carB4 Beta-lactamase CARB-4 Pseudomonas aeruginosa
P23954 6.19e-62 200 42 3 246 1 bla Beta-lactamase OXY-2 Klebsiella oxytoca
Q9F663 7.06e-62 200 44 2 228 1 bla Carbapenem-hydrolyzing beta-lactamase KPC Klebsiella pneumoniae
Q848S6 7.06e-62 200 44 2 228 1 bla Carbapenem-hydrolyzing beta-lactamase KPC Klebsiella oxytoca
P39824 3.09e-61 199 43 2 243 1 penP Beta-lactamase Bacillus subtilis (strain 168)
P22391 8.8e-61 197 41 2 248 1 bla Beta-lactamase OXY-1 Klebsiella oxytoca
Q44674 2.11e-60 197 43 2 243 3 penP Beta-lactamase Bacillus amyloliquefaciens
Q06316 2.69e-60 196 43 2 228 3 bla Beta-lactamase Amycolatopsis lactamdurans
P67919 1.3e-59 194 42 5 253 3 rob1 Beta-lactamase ROB-1 Mannheimia haemolytica
P67918 1.3e-59 194 42 5 253 3 rob1 Beta-lactamase ROB-1 Haemophilus influenzae
P67920 1.3e-59 194 42 5 253 3 rob1 Beta-lactamase ROB-1 Actinobacillus pleuropneumoniae
P80545 1.68e-59 193 39 2 258 1 None Beta-lactamase Serratia fonticola
A0A649V088 9.34e-59 192 38 3 280 1 bla Beta-lactamase CTX-M-14 Escherichia coli
Q47066 1.78e-58 191 36 6 294 1 bla Beta-lactamase Toho-1 Escherichia coli
P14560 4.15e-58 191 44 4 226 3 blaU Beta-lactamase 2 Streptomyces cacaoi
P74841 4.66e-58 190 36 6 294 3 bla Beta-lactamase CTX-M-2 Salmonella typhimurium
P35392 5.16e-58 191 44 4 228 3 blaF Beta-lactamase Streptomyces fradiae
P28585 1.14e-57 189 38 3 261 1 bla Beta-lactamase CTX-M-1 Escherichia coli
E1ANH6 1.85e-57 189 38 3 252 1 bla Beta-lactamase CTX-M-97 Escherichia coli
A0A5R8T042 3.94e-57 188 38 3 262 1 bla Beta-lactamase CTX-M-15 Escherichia coli O25b:H4
P22390 4.07e-57 188 40 6 272 1 None Beta-lactamase Citrobacter koseri
Q9RMT4 5.05e-57 187 38 3 259 1 bla Beta-lactamase CTX-M-8 Citrobacter amalonaticus
O33807 8.41e-56 184 35 6 294 1 bla Beta-lactamase CTX-M-4 Salmonella typhimurium
P10424 2.22e-55 184 39 2 249 1 penPC Beta-lactamase 1 Bacillus cereus
O65975 2.58e-55 183 35 6 294 3 bla Beta-lactamase CTX-M-5 Salmonella typhimurium
Q45726 2.68e-55 184 39 2 250 3 bla Beta-lactamase Bacillus thuringiensis
P00809 4.27e-55 183 41 2 225 3 blaY Beta-lactamase 1 Bacillus cereus
P52682 8.69e-55 182 35 5 280 1 smeA Carbapenem-hydrolyzing beta-lactamase Sme-1 Serratia marcescens
O65976 1.12e-54 181 35 6 294 3 bla Beta-lactamase CTX-M-6 Salmonella typhimurium
P00808 3.24e-54 181 41 3 226 1 penP Beta-lactamase Bacillus licheniformis
P52663 3.4e-54 180 33 4 281 1 nmcA Imipenem-hydrolyzing beta-lactamase Enterobacter cloacae
P28018 6.21e-54 180 38 2 250 3 blaCI Beta-lactamase 1 Bacillus mycoides
Q8KSA6 2.88e-53 178 38 1 247 1 bla Beta-lactamase CTX-M-25 Escherichia coli
Q59517 3.67e-53 177 46 5 228 1 blaF Beta-lactamase Mycolicibacterium fortuitum
Q03680 4.91e-53 178 38 4 258 1 blaL Beta-lactamase 1 Streptomyces cacaoi
P10509 1.27e-52 177 41 4 238 3 bla Beta-lactamase Kitasatospora aureofaciens
Q06650 1.62e-52 177 43 4 234 3 bla Beta-lactamase Streptomyces cellulosae
P80298 1.97e-52 175 40 1 218 1 None Beta-lactamase Proteus vulgaris
P52664 3.06e-52 176 41 1 218 1 blaB Beta-lactamase Proteus vulgaris
P35393 3.29e-52 176 38 4 271 3 None Beta-lactamase Streptomyces lavendulae
P06548 3.97e-52 176 37 3 249 1 blaZ Beta-lactamase 3 Bacillus cereus
P96465 7.39e-51 172 42 2 246 3 None Beta-lactamase L2 Stenotrophomonas maltophilia
Q93F76 1.3e-50 171 38 3 246 1 blaGES-2 Beta-lactamase GES-2 Pseudomonas aeruginosa
Q09HD0 9.69e-50 169 38 3 246 1 blaGES-5 Beta-lactamase GES-5 Klebsiella pneumoniae
Q9KJY7 1.21e-49 168 38 3 246 1 ges-1 Beta-lactamase GES-1 Klebsiella pneumoniae
P14559 3.62e-49 168 40 4 233 1 None Beta-lactamase Streptomyces albus G
P35391 6.92e-49 167 39 5 237 3 None Beta-lactamase Streptomyces badius
O69395 1.09e-46 161 36 7 287 3 bla Beta-lactamase Toho-2 Escherichia coli
P9WKD3 1.82e-44 155 40 5 231 1 blaC Beta-lactamase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WKD2 1.82e-44 155 40 5 231 3 blaC Beta-lactamase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
A5U493 1.82e-44 155 40 5 231 1 blaC Beta-lactamase Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
P0A5I7 1.82e-44 155 40 5 231 3 blaC Beta-lactamase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P00807 1.9e-43 152 32 5 279 1 blaZ Beta-lactamase Staphylococcus aureus
Q59514 6.34e-40 144 34 7 255 3 bla Beta-lactamase BRO-1 Moraxella catarrhalis
P37321 2.88e-16 80 28 7 223 1 per1 Extended-spectrum beta-lactamase PER-1 Pseudomonas aeruginosa
P30898 6.19e-14 73 24 9 289 3 cblA Beta-lactamase Bacteroides uniformis
P30899 7.47e-06 50 24 5 193 3 cfxA Beta-lactamase Phocaeicola vulgatus

  • Number of RefSeq hits:

General

Source Morganella morganii S2
Locus tag EHELCC_19595
Feature type CDS
Gene blaTEM-1
Product broad-spectrum class A beta-lactamase TEM-1
Location 3428 - 4288 (strand: -1)
Length 861 (nucleotides) / 286 (amino acids)

Contig

Accession ZDB_248
Length 10748 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_3778
Orthogroup size 2
N. genomes 2

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Genomic region

Domains

PF13354 Beta-lactamase enzyme family

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG2367 Defense mechanisms (V) V Beta-lactamase class A

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K18698 beta-lactamase class A TEM [EC:3.5.2.6] beta-Lactam resistance -

AMR gene Annotation(s)

Gene Description Scope Type Class Subclass HMM
blaTEM-1 broad-spectrum class A beta-lactamase TEM-1 core AMR BETA-LACTAM BETA-LACTAM NF000531 

Protein Sequence

MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW

Flanking regions ( +/- flanking 50bp)

TGAGACAATAACCCTGGTAAATGCTTCAATAATATTGAAAAAGGAAGAGTATGAGTATTCAACATTTTCGTGTCGCCCTTATTCCCTTTTTTGCGGCATTTTGCCTTCCTGTTTTTGCTCACCCAGAAACGCTGGTGAAAGTAAAAGATGCTGAAGATCAGTTGGGTGCACGAGTGGGTTACATCGAACTGGATCTCAACAGCGGTAAGATCCTTGAGAGTTTTCGCCCCGAAGAACGTTTTCCAATGATGAGCACTTTTAAAGTTCTGCTATGTGGTGCGGTATTATCCCGTGTTGACGCCGGGCAAGAGCAACTCGGTCGCCGCATACACTATTCTCAGAATGACTTGGTTGAGTACTCACCAGTCACAGAAAAGCATCTTACGGATGGCATGACAGTAAGAGAATTATGCAGTGCTGCCATAACCATGAGTGATAACACTGCTGCCAACTTACTTCTGACAACGATCGGAGGACCGAAGGAGCTAACCGCTTTTTTGCACAACATGGGGGATCATGTAACTCGCCTTGATCGTTGGGAACCGGAGCTGAATGAAGCCATACCAAACGACGAGCGTGACACCACGATGCCTGCAGCAATGGCAACAACGTTGCGCAAACTATTAACTGGCGAACTACTTACTCTAGCTTCCCGGCAACAATTAATAGACTGGATGGAGGCGGATAAAGTTGCAGGACCACTTCTGCGCTCGGCCCTTCCGGCTGGCTGGTTTATTGCTGATAAATCTGGAGCCGGTGAGCGTGGGTCTCGCGGTATCATTGCAGCACTGGGGCCAGATGGTAAGCCCTCCCGTATCGTAGTTATCTACACGACGGGGAGTCAGGCAACTATGGATGAACGAAATAGACAGATCGCTGAGATAGGTGCCTCACTGATTAAGCATTGGTAACTGTCAGACCAAGTTTACTCATATATACTTTAGATTGATTTAAAACTTCA