VFG049098


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Virulence factor VFG049098
Protein list: lists the 5 occurences of the Virulence factor within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Virulence factor of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factor has been clustered.
Orthogroups are shown in red if they are annotated with that particular Virulence factor in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Virulence factor prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factor.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factor prediction.

Description

Protein NAD-dependent epimerase
VF ID VF0561
Category Immune modulation
Protein ID WP_014838941
Characteristics In K. pneumoniae there are nine main O-serotypes. Three of these, O1, O2, and O3, are responsible for almost 80% of all Klebsiella infections.; Compared with other Enterobacteriaceae, such as Escherichia coli 161 defined O serotypes and Shigella flexneri at least 47 O serotypes, Klebsiella has a surprisingly low number of reported O serotypes which promises a more viable alternative for vaccine development compared with K-antigen-based vaccines; The O-antigen biosynthesis enzymes are encoded on the rfb locus.
Function Resistant to serum complement; also play a role in protecting bacteria from antimicrobial peptides, including polymyxin antibiotics
Vf_category_id VFC0258

Occurence in the database

VFG049098 is associated with 5 different proteins
The 5 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_249 FBDBKF_05350 78768 79781 -1 wcaG Nucleoside-diphosphate-sugar epimerase Morganella morganii S1
1 group_249 EHELCC_12240 101713 102726 1 wcaG Nucleoside-diphosphate-sugar epimerase Morganella morganii S2
2 group_249 NLDBIP_12580 101668 102681 1 wcaG Nucleoside-diphosphate-sugar epimerase Morganella morganii S4
3 group_249 LHKJJB_12440 101713 102726 1 wcaG Nucleoside-diphosphate-sugar epimerase Morganella morganii S3
4 group_249 HKOGLL_11055 101713 102726 1 wcaG Nucleoside-diphosphate-sugar epimerase Morganella morganii S5