VFG048826
Help to interpret the results
Three outputs have been generated:
General: this result contains the description and frequency of the selected Virulence factors VFG048826, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Virulence factors
within the database. 7 occurences are identified.
The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Virulence factor(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factors has been clustered.
In red the Virulence factors with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Virulence factors prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factors.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factors prediction.
Description
Protein |
glucose-1-phosphate thymidylyltransferase |
VF ID |
VF0560 |
Category |
Immune modulation |
Protein ID |
YP_005227857 |
Characteristics |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
Function |
Assisting in evading the host immune system by protecting bacteria from opsonophagocytosis and serum killing |
Vf_category_id |
VFC0258 |
Occurence in the database
VFG048826 is associated with 7 different proteins (see tab "Protein list" and "Profile") |
The 7 proteins are classified into 1 different orthogroup(s)
|
# |
Orthogroup |
Locus |
Start |
Stop |
S. |
Gene |
Product |
Organism |
0 |
group_1333 |
FBDBKF_08245 |
27477 |
28358 |
1 |
rfbA |
glucose-1-phosphate thymidylyltransferase RfbA |
Morganella morganii S1 |
1 |
group_1333 |
EHELCC_13280 |
135367 |
136248 |
-1 |
rfbA |
glucose-1-phosphate thymidylyltransferase RfbA |
Morganella morganii S2 |
2 |
group_1333 |
NLDBIP_13620 |
135367 |
136248 |
-1 |
rfbA |
glucose-1-phosphate thymidylyltransferase RfbA |
Morganella morganii S4 |
3 |
group_1333 |
LHKJJB_12935 |
26195 |
27076 |
1 |
rfbA |
glucose-1-phosphate thymidylyltransferase RfbA |
Morganella morganii S3 |
4 |
group_1333 |
HKOGLL_12095 |
135367 |
136248 |
-1 |
rfbA |
glucose-1-phosphate thymidylyltransferase RfbA |
Morganella morganii S5 |
5 |
group_1333 |
F4V73_RS18795 |
28638 |
29519 |
1 |
rfbA |
glucose-1-phosphate thymidylyltransferase RfbA |
Morganella psychrotolerans |
6 |
group_1333 |
PMI_RS16505 |
3640871 |
3641752 |
1 |
rfbA |
glucose-1-phosphate thymidylyltransferase RfbA |
Proteus mirabilis HI4320 |