VFG048620


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Virulence factors VFG048620, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Virulence factors within the database. 5 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Virulence factor(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factors has been clustered.
In red the Virulence factors with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Virulence factors prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factors.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factors prediction.

Description

Protein ferric aerobactin receptor IutA
VF ID VF0565
Category Nutritional/Metabolic factor
Protein ID WP_014907843
Characteristics Aer is typically plasmid-encoded; the siderophore Aer has been distinguished as the most common siderophore secreted by hypervirulent K. pneumoniae
Function Citrate-hydroxamate siderophore aerobactin is needed for successful infection by hypervirulent K. pneumoniae in pneumonic infections
Vf_category_id VFC0272

Occurence in the database

VFG048620 is associated with 5 different proteins (see tab "Protein list" and "Profile")
The 5 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_3034 FBDBKF_18090 18796 21009 1 cirA Outer membrane receptor protein, Fe transport Morganella morganii S1
1 group_3034 EHELCC_16790 18796 21009 1 cirA Outer membrane receptor protein, Fe transport Morganella morganii S2
2 group_3034 NLDBIP_17660 34757 36970 -1 cirA Outer membrane receptor protein, Fe transport Morganella morganii S4
3 group_3034 LHKJJB_17580 34757 36970 -1 cirA Outer membrane receptor protein, Fe transport Morganella morganii S3
4 group_3034 HKOGLL_17395 34757 36970 -1 cirA Outer membrane receptor protein, Fe transport Morganella morganii S5