VFG037990


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Virulence factor VFG037990
Protein list: lists the 6 occurences of the Virulence factor within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Virulence factor of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factor has been clustered.
Orthogroups are shown in red if they are annotated with that particular Virulence factor in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Virulence factor prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factor.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factor prediction.

Description

Protein UDP-glucose/GDP-mannose dehydrogenase family protein
VF ID VF0465
Category Immune modulation
Protein ID WP_000705810
Characteristics A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide.
Function Plays an important role in protecting bacteria from the host innate immune response
Vf_category_id VFC0258

Occurence in the database

VFG037990 is associated with 6 different proteins
The 6 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_462 FBDBKF_05355 79790 81133 -1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S1
1 group_462 EHELCC_12235 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S2
2 group_462 NLDBIP_12575 100316 101659 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S4
3 group_462 LHKJJB_12435 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S3
4 group_462 HKOGLL_11050 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S5
5 group_462 F4V73_RS05810 1236699 1238042 -1 UDP-glucose/GDP-mannose dehydrogenase family protein Morganella psychrotolerans