VFG037990


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Virulence factors VFG037990, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Virulence factors within the database. 6 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Virulence factor(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Virulence factors has been clustered.
In red the Virulence factors with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Virulence factors prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Virulence factors.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Virulence factors prediction.

Description

Protein UDP-glucose/GDP-mannose dehydrogenase family protein
VF ID VF0465
Category Immune modulation
Protein ID WP_000705810
Characteristics A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide.
Function Plays an important role in protecting bacteria from the host innate immune response
Vf_category_id VFC0258

Occurence in the database

VFG037990 is associated with 6 different proteins (see tab "Protein list" and "Profile")
The 6 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_970 FBDBKF_05355 79790 81133 -1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S1
1 group_970 EHELCC_12235 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S2
2 group_970 NLDBIP_12575 100316 101659 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S4
3 group_970 LHKJJB_12435 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S3
4 group_970 HKOGLL_11050 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S5
5 group_970 F4V73_RS05810 1236699 1238042 -1 UDP-glucose/GDP-mannose dehydrogenase family protein Morganella psychrotolerans